Ketoconazole

Zamkati

• Musanamwe ketoconazole,
• Ketoconazole imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Zizindikiro zotsatirazi sizachilendo, koma ngati mungakumane ndi zina mwazomwe zalembedwa m'gawo la CHENJEZO, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Ketoconazole iyenera kugwiritsidwa ntchito kokha kuchiza matenda a mafangasi ngati mankhwala ena sapezeka kapena sangaloledwe.

Ketoconazole imatha kuwononga chiwindi, nthawi zina imakhala yayikulu mokwanira kufuna kuziyika chiwindi kapena kupha. Kuwonongeka kwa chiwindi kumatha kupezeka mwa anthu omwe alibe matenda a chiwindi kapena zina zilizonse zomwe zimawonjezera chiopsezo choti chiwindi chidzawonongeka. Uzani dokotala wanu ngati mumamwa kapena mumamwa mowa wambiri komanso ngati mwakhalapo ndi matenda a chiwindi. Musamwe zakumwa zoledzeretsa zilizonse mukamamwa mankhwala a ketoconazole chifukwa kumwa zakumwa zoledzeretsa kumawonjezera chiopsezo choti chiwindi chimawonongeka.Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: kutopa kwambiri, kusowa chilakolako, kuchepa thupi, nseru, kusanza, chikasu pakhungu kapena maso, mkodzo wachikaso wakuda, mipando yotumbululuka, ululu kumtunda kwakumanja kwa m'mimba, malungo, kapena zidzolo.

Ketoconazole imatha kuyambitsa kutalikirana kwa QT (mtima wosasintha wamtima womwe ungayambitse kukomoka, kutaya chidziwitso, kugwidwa, kapena kufa mwadzidzidzi). Musatenge disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), pimozide (Orap), quinidine (Quinidex, Quinaglute), cisapride (Propulsid; sichikupezeka ku US), methadone (Dolophine, Methadose), ndi ranolazine (Ranexa) mukamamwa ketoconazole. Ngati mukukumana ndi zina mwazizindikiro izi, siyani kumwa ketoconazole ndipo itanani dokotala wanu mwachangu: mwachangu, mwamphamvu, kapena kugunda kwamtima mosasinthasintha; kukomoka; chizungulire; mutu wopepuka; kapena kutaya chidziwitso.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti aone momwe thupi lanu likuyankhira ketoconazole.

Dokotala wanu kapena wamankhwala amakupatsirani pepala lazidziwitso za wopanga (Medication Guide) mukayamba kulandira mankhwala ndi ketoconazole ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kwa kumwa ketoconazole.

Ketoconazole imagwiritsidwa ntchito pochiza matenda a mafangasi ngati mankhwala ena sapezeka kapena sangaloledwe. Ketoconazole sayenera kugwiritsidwa ntchito pochiza fungal meningitis (matenda amimbidwe oyandikira ubongo ndi msana wam'mimba chifukwa cha fungus) kapena matenda amisomali am'fungasi. Ketoconazole ali mgulu la antifungals lotchedwa imidazoles. Zimagwira ntchito pochepetsa kukula kwa bowa komwe kumayambitsa matenda.

Ketoconazole imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku Imwani ketoconazole mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani ketoconazole ndendende monga mwadongosolo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu akhoza kukulitsa mlingo wanu ngati vuto lanu silikuyenda bwino.

Mungafunike kumwa ketoconazole kwa miyezi 6 kapena kupitilira apo kuti muchiritse matenda anu. Pitirizani kumwa ketoconazole mpaka dokotala atakuuzani kuti muyenera kusiya, ngakhale mutakhala bwino. Osasiya kumwa ketoconazole osalankhula ndi dokotala. Mukasiya kumwa ketoconazole posachedwa, matenda anu amatha kubwerera patapita nthawi yochepa.

Mlingo waukulu wa ketoconazole nthawi zina amagwiritsidwa ntchito pochiza matenda a Cushing (zomwe zimachitika pakakhala mahomoni ochulukirapo m'thupi) komanso khansa ya Prostate (khansa ya chiberekero chamwamuna). Ketoconazole sanawonetsedwe kuti ndi yotetezeka kapena yogwira ntchito izi. Lankhulani ndi dokotala wanu za kugwiritsa ntchito ketoconazole pa matenda anu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanamwe ketoconazole,

• auzeni adotolo ndi azachipatala ngati mankhwala a ketoconazole kapena mankhwala ena aliwonse sagwirizana ndi mapiritsi a ketoconazole. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu ngati mukumwa alprazolam (Niravam, Xanax); eplerenone (Inspra); ergot alkaloids monga ergotamine (Ergomar, ku Cafergot, ku Migergot), dihydroergotamine (DHH 45, Migranal), ndi methylergonovine (Methergine); felodipine (Kukongola); irinotecan (Camptosar); lovastatin (Mevacor); lurasidone (Latuda); midazolam (Ndime); nisoldipine (Sular); simvastatin (Zocor); tolvaptan (Samsca); ndi triazolam (Halcion). Dokotala wanu angakuuzeni kuti musamwe ketoconazole ngati mukumwa mankhwala amodzi kapena angapo kapena mankhwala aliwonse omwe ali mgawo la CHENJEZO LOFUNIKA.
• uzani dokotala ndi wamankhwala mankhwala ena akuchipatala ndi osapereka, mavitamini, zowonjezera zakudya, ndi mankhwala omwe mumamwa. Onetsetsani kuti mwatchula mankhwala omwe adatchulidwa mu gawo LOFUNIKITSA CHENJEZO ndi zina mwa izi: aliskiren (Tekturna, ku Valturna, ku Amturnide); anticoagulants ('magazi ochepetsa magazi') monga dabigatran (Pradaxa), rivaroxaban powder (Xarelto) ndi warfarin (Coumadin); Aprepitant (Emend); aripiprazole (Limbikitsani); atorvastatin (Lipitor); chifuwa (Tracleer); budesonide (Uceris); buspirone (BuSpar); carbamazepine (Tegretol); zotchinga calcium monga amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), nifedipine (Adalat, Procardia), ndi verapamil (Calan, Covera, Isoptin, Verelan); mankhwala a khansa monga bortezomib (Velcade); busulfan (Myleran); dasatinib (Sprycel); docetaxel (Taxotere), erlotinib (Tarceva); mapiritsi a powder (Ixempra); lapatinib (Tykerb); nilotinib (Tasigna); paclitaxel (Taxol), trimetrexate (Neutrexin), vincristine (Vincasar), vinblastine, ndi vinorelbine (Navelbine); ciclesonide (Alvesco); cilostazol (Pletal); cinacalcet (Sensipar); colchicine (Colcrys, mu Col-Probenecid); dexamethasone; digoxin (Lanoxin); eletriptan (Relpax); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis); fesoterodine (Toviaz); fluticasone (Flonase, Flovent); haloperidol (Haldol); Mankhwala a HIV monga darunavir (Prezista), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), maraviroc (Selzentry), nevirapine (Viramune), ritonavir (Norvir), ndi saquinavir (Invirase, Fortovase); ma immunosuppressants monga cyclosporine (Neoral, Sandimmune), everolimus (Afinitor, Zortress), sirolimus (Rapamune), ndi tacrolimus (Prograf); imatinib (Gleevec); mankhwala a erectile dysfunction monga sildenafil (Viagra), tadalafil (Cialis), ndi vardenafil (Levitra); mankhwala a kudzimbidwa, kutentha pa chifuwa, kapena zilonda monga cimetidine (Tagamet), famotidine (Pepcid), lansoprazole (Prevacid), nizatidine (Axid), omeprazole (Prilosec), ndi ranitidine (Zantac); mankhwala ochizira TB monga isoniazid (INH, Nydrazid), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane); methylprednisolone (Medrol); kusokoneza (Corgard); oxycodone (Oxecta, Oxy Contin, ku Percocet, ena); phenytoin (Dilantin); praziquantel (Biltricide); quetiapine (Seroquel); mphukira (Rozerem); repaglinide (Prandin, mu PrandiMet); risperidone (Risperdal); salmeterol (Serevent, ku Advair); saxagliptin (Onglyza); solifenacin (Vesicare); ma immunosuppressants monga cyclosporine (Neoral, Sandimmune), sirolimus (Rapamune), ndi tacrolimus (Prograf); tamsulosin (Flomax, ku Jalyn); telithromycin (Ketek); ndi tolterodine (Detrol). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi ketoconazole, chifukwa chake onetsetsani kuti mumauza dokotala za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• ngati mukumwa mankhwala ophera asidi okhala ndi aluminium, calcium, kapena magnesium (Maalox, Mylanta, Tums, ndi ena), tengani ola limodzi musanadye kapena maola awiri mutamwa ketoconazole.
• uzani adotolo ngati mwakhala mukukhalapo ndi zomwe zatchulidwa mgawo LOFUNIKITSA CHENJEZO kapena kusakwanira kwa adrenal (mkhalidwe womwe zopangitsa za adrenal sizimapanga mahomoni okwanira a steroid).
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga ketoconazole, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa ketoconazole.
• muyenera kudziwa kuti kumwa zakumwa zoledzeretsa (kuphatikizapo vinyo, mowa, ndi mankhwala omwe ali ndi mowa monga mankhwala a chifuwa) mukamamwa ketoconazole kumawonjezera chiopsezo choti chiwindi chitha kuwonongeka ndipo zimatha kuyambitsa zizindikilo zosasangalatsa monga kuphulika, kuthamanga, mseru, kupweteka mutu, ndi kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi ngati mumamwa mowa mukamwa ketoconazole.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Ketoconazole imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kupweteka m'mimba
• kutsegula m'mimba
• kudzimbidwa
• kutentha pa chifuwa
• mpweya
• kusintha kwa kulawa chakudya
• pakamwa pouma
• sinthani mtundu wa lilime
• kuvuta kugona kapena kugona
• manjenje
• dzanzi, kutentha, kapena kumva kulira kwa manja kapena mapazi
• kupweteka kwa minofu
• kutayika tsitsi
• kuchapa
• kuzizira
• kutengeka ndi kuwala
• mwazi wa m'mphuno
• kukulitsa mawere mwa amuna
• kuchepa mphamvu zogonana

Zotsatira zina zoyipa zingakhale zazikulu. Zizindikiro zotsatirazi sizachilendo, koma ngati mungakumane ndi zina mwazomwe zalembedwa m'gawo la CHENJEZO, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• zidzolo
• ming'oma
• kuyabwa
• kutupa kwa maso, nkhope, milomo, lilime, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• kuvuta kupuma kapena kumeza
• kutopa kapena kufooka

Ketoconazole imatha kuchepa umuna (umuna wamwamuna woberekera) womwe umatulutsidwa, makamaka ukamamwa kwambiri. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati ndinu bambo ndipo mukufuna kukhala ndi ana.

Ketoconazole imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musanayezetsedwe kwa labotale, uzani adotolo ndi ogwira nawo ntchito kuti mukumwa ketoconazole.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu ngati muli ndi mafunso okhudza kudzaza mankhwala anu. Ngati muli ndi zizindikiro za matenda mukamaliza ketoconazole, itanani dokotala wanu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Nizoral^®