Zonisamide
Zamkati
- Musanatenge zonisamide,
- Zonisamide angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- Zotsatira zina zoyipa zingakhale zazikulu. Zizindikiro zotsatirazi sizachilendo, koma ngati mungakumane ndi zina mwazi, itanani dokotala wanu mwachangu:
- Zizindikiro za bongo zingaphatikizepo:
Zonisamide imagwiritsidwa ntchito limodzi ndi mankhwala ena kuti athetse matenda ena. Zonisamide ali mgulu la mankhwala otchedwa anticonvulsants. Zimagwira ntchito pochepetsa magwiridwe antchito amagetsi muubongo.
Zonisamide amabwera ngati kapisozi kuti atenge pakamwa. Nthawi zambiri amatengedwa kamodzi kapena kawiri patsiku kapena wopanda chakudya. Kukuthandizani kukumbukira kukumbukira kutenga zonisamide, tengani nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani zonisamide ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.
Kumeza makapisozi lonse; osagawana, kutafuna, kapena kuwaphwanya.
Dokotala wanu mwina angakuyambitseni pa mlingo wochepa wa zonisamide ndipo pang'onopang'ono muwonjezere mlingo wanu, osati kangapo kamodzi pa milungu iwiri iliyonse.
Zonisamide itha kuthandizira kuwongolera matenda anu koma sangachiritse. Zitha kutenga milungu iwiri kapena kupitilira apo kuti mumve kupindula ndi zonisamide. Pitirizani kutenga zonisamide ngakhale mukumva bwino. Osasiya kumwa zonisamide osalankhula ndi dokotala, ngakhale mutakhala ndi zovuta zina monga kusintha kosasintha kwamakhalidwe kapena malingaliro. Mukasiya mwadzidzidzi kutenga zonisamide, kugwidwa kwanu kumatha kukulira. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono.
Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi zonisamide ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.
Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.
Musanatenge zonisamide,
- uzani dokotala ndi wazamankhwala ngati simukugwirizana ndi zonisamide, diuretics ('mapiritsi amadzi'), mankhwala akumwa a shuga, mankhwala a sulfa, kapena mankhwala ena aliwonse.
- Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: amiodarone (Cordarone, Pacerone); ma antifungals monga itraconazole (Sporanox) ndi ketoconazole (Nizoral); carbonic anhydrase inhibitors monga acetazolamide (Diamox) ndi methazolamide; clarithromycin (Biaxin, mu Prevpac); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (EES, E-Mycin, Erythrocin); fluvoxamine (Luvox); HIV protease inhibitors monga indinavir (Crixivan), nelfinavir (Viracept), ndi ritonavir (Norvir, ku Kaletra); mankhwala a matenda opunduka, matumbo, matenda a Parkinson, zilonda, kapena mavuto amikodzo; Mankhwala ena ogwidwa kuphatikizapo carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin, Phenytek), ndi valproic acid (Depakene, Depakote); nefazodone (Serzone); njira zolerera za mahomoni (mapiritsi olera, zigamba, mphete, ndi jakisoni); pioglitazone (Actos, mu Actoplus, mu Duetact); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); troleandomycin (TAO) (sikupezeka ku U.S.); ndi verapamil (Calan, Covera, Isoptin, Verelan). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
- uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
- Uzani dokotala wanu ngati mukutsatira zakudya za ketogenic (mafuta ambiri, zakudya zopatsa mphamvu zama kabohydrate omwe amagwiritsidwa ntchito poletsa khunyu) kapena ngati mwakhala mukudwala kapena kupuma, chiwindi cha impso, kapena matenda am'mapapo. Muuzeni dokotala wanu ngati muli ndi matenda otsekula m'mimba tsopano, kapena ngati mukudwala m'mimba nthawi iliyonse mukamamwa mankhwala.
- Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamalandira chithandizo. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukatenga zonisamide, itanani dokotala wanu.
- uzani dokotala wanu ngati mukuyamwitsa. Mukamayamwitsa mukamamwa mankhwala, mwana wanu atha kulandira zonisamide mumkaka wa m'mawere. Onetsetsani mwana wanu kwambiri kuti agone tulo tachilendo kapena kunenepa kwambiri.
- ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa zonisamide.
- muyenera kudziwa kuti zonisamide imatha kukupangitsani kugona. Osayendetsa galimoto, kugwiritsa ntchito makina, kapena kuchita zinthu zowopsa kufikira mutadziwa momwe mankhwalawa amakukhudzirani.
- muyenera kudziwa kuti zonisamide imatha kuchepetsa thupi kutuluka thukuta ndikupangitsa kuti thupi lanu lizizizira kuzizira likatentha kwambiri. Izi zimachitika nthawi zambiri nyengo yotentha komanso kwa ana omwe amatenga zonisamide. (Ana sayenera kumwa zonisamide, koma nthawi zina, amatha kulembedwa ndi adotolo.) Muyenera kupewa kutentha ndi kuyimbira dokotala nthawi yomweyo ngati muli ndi malungo kapena / kapena simukutuluka thukuta mwachizolowezi.
- muyenera kudziwa kuti thanzi lanu lamisala lingasinthe m'njira zosayembekezereka ndipo mutha kudzipha (kuganiza zodzipweteka kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero) mukamamwa zonisamide kuti muzitha khunyu, matenda amisala, kapena mavuto ena. Chiwerengero chochepa cha achikulire ndi ana azaka 5 zakubadwa kapena kupitilira (pafupifupi 1 mwa anthu 500) omwe adatenga ma anticonvulsants monga zonisamide kuti athetse mavuto osiyanasiyana panthawi yamaphunziro azachipatala adadzipha panthawi yomwe amalandira chithandizo. Ena mwa anthuwa adayamba kudzipha pakangotha sabata limodzi atayamba kumwa mankhwalawo. Pali chiopsezo kuti mutha kusintha kusintha kwaumoyo wanu ngati mutamwa mankhwala a anticonvulsants monga zonisamide, koma pakhoza kukhala pachiwopsezo kuti mungasinthe thanzi lanu lam'mutu ngati matenda anu sakuchiritsidwa. Inu ndi dokotala wanu muwona ngati kuopsa kokumwa mankhwala a anticonvulsant ndiokulirapo kuposa kuopsa kosamwa mankhwalawo. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: mantha; kusakhazikika kapena kusakhazikika; kukwiya kwatsopano kapena kukulira, nkhawa, kapena kukhumudwa; kuchita zofuna zawo; kuvuta kugona kapena kugona; aukali, aukali, kapena achiwawa; mania (kukwiya, kusangalala modabwitsa); kuyankhula kapena kuganiza zofuna kudzipweteka kapena kudzipha; kudzipatula kwa abwenzi ndi abale; kutanganidwa ndi imfa ndi kufa; kupereka zinthu zamtengo wapatali; kapena kusintha kwina kulikonse pamakhalidwe kapena malingaliro. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.
Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.
Imwani magalasi 6-8 tsiku lililonse mukamachiza zonisamide.
Lankhulani ndi dokotala wanu zomwe mungachite ngati mwaphonya mlingo wa zonisamide. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.
Zonisamide angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- nseru
- kusanza
- kuonda
- kusintha kwa kukoma
- kutsegula m'mimba
- kudzimbidwa
- kutentha pa chifuwa
- pakamwa pouma
- mutu
- chizungulire
- chisokonezo
- kupsa mtima
- kuvuta kugona kapena kugona
- kuvuta ndi kukumbukira
- kupweteka, kuwotcha, kuchita dzanzi, kapena kumva kupweteka m'manja kapena m'mapazi
- mayendedwe osalamulirika amaso
- masomphenya awiri
Zotsatira zina zoyipa zingakhale zazikulu. Zizindikiro zotsatirazi sizachilendo, koma ngati mungakumane ndi zina mwazi, itanani dokotala wanu mwachangu:
- zidzolo
- kuphulika kapena khungu
- kuwonongeka kapena kugwidwa kwanthawi yayitali
- kupweteka msana
- kupweteka m'mimba
- kupweteka pokodza
- mkodzo wamagazi kapena wamdima
- malungo, zilonda zapakhosi, kuzizira, chifuwa, ndi zizindikiro zina za matenda
- zilonda mkamwa
- kuvulaza kosavuta
- kuvuta kuganiza kwamawu kapena kulephera kuyankhula
- kuvuta kuganiza kapena kusamala
- kusowa kwa mgwirizano
- kuyenda movutikira
- kufooka kwakukulu
- kupweteka kwambiri kwa minofu
- kutopa kwambiri
- kusowa chilakolako
- kuthamanga, kupuma pang'ono
- kugunda kwamtima kosasintha
- kutaya chidziwitso
Zonisamide angayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.
Zonisamide ingayambitse kagayidwe kachakudya acidosis (misinkhu yotsika modabwitsa ya chinthu china chachilengedwe m'magazi). Metabolic acidosis yomwe imasiyidwa osalandira chithandizo kwa nthawi yayitali imatha kuonjezera ngozi kuti mavuto ena azachipatala, kuphatikiza miyala ya impso ndi mafupa omwe angayambitse kusweka, adzayamba. Kusagwiritsa ntchito kagayidwe kachakudya acidosis kungayambitsenso kukula kocheperako komanso kutsika kwa kutalika komaliza kwa ana. Lankhulani ndi dokotala wanu za kuopsa kotenga zonisamide.
Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).
Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana.Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).
Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.
Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org
Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.
Zizindikiro za bongo zingaphatikizepo:
- kugunda kochedwa mtima
- kupuma pang'ono
- chizungulire
- kukomoka
- chikomokere (kutaya chidziwitso kwakanthawi)
Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena a labu kuti aone kuyankha kwa thupi lanu ku zonisamide.
Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.
Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.
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