Jekeseni wa Vincristine

Zamkati

• Asanalandire vincristine,
• Vincristine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, pitani kuchipatala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo:

Vincristine ayenera kuperekedwa mumitsempha yokha. Komabe, imatha kutayikira minofu yoyandikana nayo yomwe imakhumudwitsa kwambiri kapena kuwonongeka. Dokotala wanu kapena namwino adzayang'anira tsamba lanu loyang'anira izi. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: kupweteka, kuyabwa, kufiira, kutupa, matuza, kapena zilonda m'malo omwe munabayira mankhwala.

Vincristine ayenera kuperekedwa kokha moyang'aniridwa ndi dokotala wodziwa kugwiritsa ntchito mankhwala a chemotherapy.

Vincristine imagwiritsidwa ntchito limodzi ndi mankhwala ena a chemotherapy kuti athetse mitundu ina ya leukemia (khansa yamagazi oyera), kuphatikiza khansa ya myeloid leukemia (AML, ANLL) ndi acute lymphoblastic leukemia (ALL), Hodgkin's lymphoma (matenda a Hodgkin), ndi -Hodgkin's lymphoma (mitundu ya khansa yomwe imayamba mumtundu wama cell oyera omwe nthawi zambiri amalimbana ndi matenda). Vincristine imagwiritsidwanso ntchito limodzi ndi mankhwala ena a chemotherapy kuti athetse chotupa cha Wilms (mtundu wa khansa ya impso yomwe imapezeka mwa ana), neuroblastoma (khansa yomwe imayamba m'mitsempha yamitsempha ndipo imachitika makamaka mwa ana), ndi rhabdomyosarcoma (khansa yomwe imapanga minofu mwa ana). Vincristine ali mgulu la mankhwala otchedwa vinca alkaloids. Zimagwira pochepetsa kapena kuletsa kukula kwa maselo a khansa mthupi lanu.

Vincristine amabwera ngati yankho (madzi) kuti alowe jakisoni (mumtsempha) ndi dokotala kapena namwino kuchipatala. Nthawi zambiri amaperekedwa kamodzi pamlungu. Kutalika kwa chithandizo kumatengera mitundu ya mankhwala omwe mukumwa, momwe thupi lanu limayankhira, komanso mtundu wa khansa yomwe muli nayo.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu kapena kusintha mlingo wanu ngati mukukumana ndi zovuta zina. Ndikofunika kuti muuze adotolo momwe mukumvera mukamalandira jakisoni wa vincristine.

Dokotala wanu angakuuzeni kuti mutenge chopukutira pansi kapena mankhwala ofewetsa tuvi tolimba kuti muteteze kudzimbidwa mukamamwa jakisoni wa vincristine.

Vincristine amagwiritsidwanso ntchito pochiza mitundu ina ya zotupa zamaubongo, mitundu ina ya khansa yamapapo, multipleeloma (mtundu wa khansa ya m'mafupa), khansa ya m'magazi (CLL; mtundu wa khansa yamagazi oyera), Kaposi's sarcoma (mtundu wa khansa womwe umayambitsa minofu yosazolowereka kumera m'malo osiyanasiyana amthupi) wokhudzana ndi matenda a immunodeficiency (AIDS), Ewings sarcoma (mtundu wa khansa m'mafupa kapena minofu), ndi zotupa za gestational trophoblastic (mtundu wa chotupa zomwe zimapanga mkati mwa chiberekero cha mayi ali ndi pakati). Vincristine nthawi zina amagwiritsidwanso ntchito pochizira thrombotic thrombocytopenic purpura (TPP; matenda amwazi omwe amachititsa kuti magazi aumbike m'mitsempha yaying'ono mthupi). Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire vincristine,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la vincristine, mankhwala ena aliwonse, kapena zina zilizonse zopangira jekeseni ya vincristine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala ndi wamankhwala mankhwala ena omwe mumalandira kapena mavitamini omwe mumamwa kapena mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: aprepitant (Emend); carbamazepine (Tegretol); antifungals ena monga itraconazole (Sporanox), ketoconazole (Nizoral), voriconazole (Vfend), ndi posaconazole (Noxafil); clarithromycin (Biaxin, mu Prevpac); darifenacin (Enablex); dexamethasone (Decadron); fesoterodine (Toviaz); HIV protease inhibitors kuphatikiza atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); nefazodone; oxybutynin (Ditropan, Ditropan XL, Oxytrol); phenobarbital; phenytoin (Dilantin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); rifapentine (Priftin); solifenacin (Vesicare); telithromycin (Ketek); trospium (Sanctura); kapena tolterodine (Detrol, Detrol LA). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• Uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi vuto lomwe limakhudza mitsempha yanu. Dokotala wanu sangakonde kuti mulandire jakisoni wa vincristine.
• uzani dokotala wanu ngati mukumva kapena mwakhalapo ndi mankhwala a radiation (x-ray), ngati muli ndi matenda, kapena ngati mwakhalapo ndi matenda am'mapapo kapena a chiwindi.
• muyenera kudziwa kuti vincristine imatha kusokoneza msambo mwa azimayi ndipo amatha kuyimitsa umuna mwa amuna kwakanthawi kochepa kapena kosatha. Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Simuyenera kutenga pakati kapena kuyamwa mukalandira jekeseni wa vincristine. Mukakhala ndi pakati mukalandira jakisoni wa vincristine, itanani dokotala wanu. Vincristine atha kuvulaza mwana wosabadwayo.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Vincristine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• zilonda mkamwa ndi pakhosi
• kusowa chilakolako kapena kunenepa
• kupweteka m'mimba
• kutsegula m'mimba
• mutu
• kutayika tsitsi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, pitani kuchipatala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• ming'oma
• zidzolo
• kuyabwa
• kuvuta kupuma kapena kumeza
• kudzimbidwa
• kuchulukitsa kapena kuchepa pokodza
• kutupa kwa nkhope, mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
• kutuluka mwachilendo kapena kuphwanya
• kutopa kapena kufooka kosazolowereka
• kupweteka, dzanzi, kutentha, kapena kumva kulasalasa m'manja kapena m'mapazi
• kuyenda movutikira kapena kuyenda mosakhazikika
• kupweteka kwa minofu kapena molumikizana
• kusintha kwadzidzidzi m'masomphenya, kuphatikizapo kutayika kwa masomphenya
• kutaya kumva
• chizungulire
• kutaya mphamvu yosuntha minofu ndikumverera gawo la thupi
• kusasamala kapena kulephera kuyankhula mofuula
• kugwidwa
• kupweteka kwa nsagwada
• malungo, zilonda zapakhosi, kuzizira, kapena zizindikiro zina za matenda

Vincristine akhoza kuonjezera chiopsezo kuti mudzadwala khansa zina. Lankhulani ndi dokotala wanu za kuopsa kolandila jakisoni wa vincristine.

Vincristine amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• kugwidwa
• kudzimbidwa kwakukulu
• kupweteka m'mimba
• kutuluka mwachilendo kapena kuphwanya

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti aone momwe thupi lanu lingayankhire vincristine.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Oncovin^®¶
• Vincasar^® Zolemba
• Vincrex^®¶

• Leurocristine Sulfate
• LCR
• VCR

^¶ Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.