Jekeseni wa Leuprolide

Zamkati

• Musanalandire jakisoni wa leuprolide,
• Kubayira kwa Leuprolide kumatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

Jekeseni wa Leuprolide (Eligard, Lupron Depot) amagwiritsidwa ntchito pochiza matenda omwe amabwera ndi khansa ya prostate. Jekeseni wa Leuprolide (Lupron Depot-PED, Fensolvi) amagwiritsidwa ntchito kwa ana azaka 2 kapena kupitilira kuti athetse msinkhu wapakati (CPP; zomwe zimapangitsa atsikana [nthawi zambiri ochepera zaka 8) ndi anyamata [nthawi zambiri amakhala ochepera zaka 9 msinkhu] kulowa msinkhu msanga msanga, zomwe zimabweretsa kufulumira kuposa kukula kwamfupa ndikukula kwamakhalidwe azakugonana). Jekeseni wa Leuprolide (Lupron Depot) amagwiritsidwa ntchito payekha kapena ndi mankhwala ena (norethindrone) kuchiza endometriosis (vuto lomwe mtundu wa minofu yomwe imayendetsa chiberekero [chiberekero] umakula m'malo ena amthupi ndipo umayambitsa kupweteka, kusamba kwambiri kapena kusamba nthawi zonse [nthawi], ndi zizindikiro zina). Jekeseni wa Leuprolide (Lupron Depot) imagwiritsidwanso ntchito ndi mankhwala ena kuchiza kuchepa kwa magazi (kuchuluka kocheperako kwama cell ofiira ofiira) oyambitsidwa ndi uterine fibroids (zopitilira muyeso m'mimba mwa chiberekero). Jakisoni wa Leuprolide ali mgulu la mankhwala otchedwa gonadotropin-release hormone (GnRH) agonists. Zimagwira ntchito pochepetsa kuchuluka kwa mahomoni ena m'thupi.

Jakisoni wa Leuprolide amabwera ngati kuyimitsidwa kwanthawi yayitali (Lupron) komwe kumabayidwa mu mnofu (mu mnofu) ndi dokotala kapena namwino kuofesi yazachipatala kapena kuchipatala ndipo nthawi zambiri amapatsidwa kamodzi pamwezi (Lupron Depot, Lupron Depot-PED) kapena iliyonse Miyezi 3, 4, kapena 6 (Lupron Depot-3 mwezi, Lupron Depot-PED-3 mwezi, Lupron Depot-4 mwezi, Lupron Depot-Mwezi 6). Jakisoni wa Leuprolide amabweranso ngati kuyimitsidwa kwanthawi yayitali (Eligard) komwe kumabayidwa pansi (pansi pa khungu) ndi dokotala kapena namwino kuofesi yazachipatala kapena kuchipatala ndipo nthawi zambiri amapatsidwa miyezi 1, 3, 4, kapena 6 iliyonse. Jakisoni wa Leuprolide amabweranso ngati kuyimitsidwa kwanthawi yayitali (Fensolvi) komwe kumabayidwa mozungulira (pansi pa khungu) ndi dokotala kapena namwino kuofesi yazachipatala kapena kuchipatala ndipo nthawi zambiri amapatsidwa miyezi isanu ndi umodzi iliyonse. Dokotala wanu angakuuzeni kuti chithandizo chanu ndi jakisoni wa leuprolide chikhala motalika bwanji. Mukagwiritsidwa ntchito mwa ana omwe ali ndi msinkhu wotha msinkhu, jekeseni wa leuprolide (Lupron Depot-PED, Lupron Depot-PED-3 mwezi, Fensolvi) mwina adzaimitsidwa ndi dokotala wa mwana wanu asanakwanitse zaka 11 mwa atsikana komanso azaka 12 mwa anyamata.

Mukalandira kuyimitsidwa kwa leuprolide kwa nthawi yayitali (Eligard) ngati jakisoni wocheperako, mutha kuwona khunyu kakang'ono pomwe jekeseni munapatsidwa mukamalandira mankhwala. Bump iyi iyenera kutha.

Leuprolide imatha kubweretsa kuwonjezeka kwa mahomoni ena m'masabata angapo oyamba atalandira jakisoni. Dokotala wanu adzakuyang'anirani mosamala pazizindikiro zatsopano kapena zowonjezereka panthawiyi.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanalandire jakisoni wa leuprolide,

• uzani adotolo ndi wazamankhwala ngati muli ndi vuto la leuprolide, goserelin (Zoladex), histrelin (Supprelin LA, Vantas), nafarelin (Synarel), triptorelin (Triptodur, Trelstar), mankhwala ena aliwonse, kapena chilichonse chothandizira mu jakisoni wa leuprolide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala ena am'magazi osagwirizana monga amiodarone (Cordarone), disopyramide (Norpace), procainamide (Procanbid), quinidine, ndi sotalol (Betapace, Betapace AF, Sorine); buproprion (Aplenzin, Forfivo, Wellbutrin, mu Contrave); mankhwala a khunyu; oral steroids monga dexamethasone (Hemady), methylprednisolone (Medrol), ndi prednisone (Rayos); ndi serotonin reuptake inhibitors (SSRIs) monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, mu Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil), ndi sertraline (Zoloft). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi leuprolide, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• Uzani dokotala wanu ngati muli ndi magazi achilendo azimayi. Dokotala wanu angakuuzeni kuti musagwiritse ntchito jakisoni wa leuprolide.
• auzeni adotolo ngati inu kapena wina aliyense m'banja mwanu adadwala matenda a osteoporosis (momwe mafupa amafupikira komanso amatha kuthyoka); ngati muli ndi mbiri yakumwa mowa kapena kugwiritsa ntchito fodya kwanthawi yayitali; kapena ngati mwakhalapo ndi vuto lakukhumudwa, khunyu, zotupa zamaubongo, khansa yomwe yafalikira msana (msana), matenda ashuga, kutsekeka kwamikodzo (kutsekeka komwe kumayambitsa kukodza), magazi mumkodzo wanu, nthawi yayitali ya QT (chosowa vuto la mtima lomwe lingayambitse kugunda kwamtima, kukomoka, kapena kufa mwadzidzidzi), matenda am'mitsempha (kutseka kapena kufooketsa mitsempha yamagazi mkati mwaubongo kapena kupita kuubongo), matenda amtima, kapena potaziyamu, calcium, kapena magnesium magazi anu.
• Muyenera kudziwa kuti leuprolide sayenera kugwiritsidwa ntchito kwa amayi omwe ali ndi pakati, atha kutenga pakati, kapena akuyamwitsa. Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Dokotala wanu amatha kuyesa kuti akhale ndi pakati kuti atsimikizire kuti mulibe pakati mukayamba kulandira jakisoni wa leuprolide. Muyenera kugwiritsa ntchito njira yodalirika yopewera mahomoni kuti muchepetse kutenga pakati mukalandira jakisoni wa leuprolide. Lankhulani ndi dokotala wanu za mitundu yoletsa yomwe ili yoyenera kwa inu, ndipo pitirizani kugwiritsa ntchito njira zolerera ngakhale simukuyenera kusamba nthawi zonse mukamalandira chithandizo. Ngati mukuganiza kuti mwakhala ndi pakati mukalandira jakisoni wa leuprolide, itanani dokotala wanu mwachangu. Jekeseni ya Leuprolide itha kuvulaza mwana wosabadwayo.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya nthawi yoti mulandire jakisoni wa leuprolide, muyenera kuyitanitsa omwe amakuthandizani nthawi yomweyo kuti akonzenso nthawi yanu.

Kubayira kwa Leuprolide kumatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutopa
• kutentha (kutentha kwadzidzidzi kwa kutentha thupi kapena kutentha), thukuta, kapena kuwuma
• kupweteka kwa m'mawere, kupweteka, kapena kusintha kwa kukula kwa bere mwa abambo ndi amai
• kutuluka kwa ukazi, kuuma, kapena kuyabwa mwa amayi
• kutuluka (kutuluka magazi kumaliseche) kapena kusamba (nthawi)
• kuchepa kwa machende
• amachepetsa kuthekera kwakugonana kapena chilakolako
• kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi
• kupweteka, kuwotcha, kapena kumva kulasalasa m'manja kapena m'mapazi
• kupweteka, kuwotcha, kufinya, kufiira, kapena kuumitsa pamalo pomwe kunabayidwa jakisoni
• kusintha kulemera
• kupweteka kwa minofu kapena molumikizana
• chimfine, kukhosomola, zilonda zapakhosi, kapena zizindikiro zonga chimfine
• malungo
• kupweteka m'mimba
• kudzimbidwa
• mutu
• ziphuphu
• kukhumudwa
• osatha kuletsa kukhumudwa komanso kusinthasintha kwamalingaliro
• manjenje
• Kumva kusapeza bwino kapena kusakhazikika
• kuvuta ndi kukumbukira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• kuyabwa, zidzolo, kapena ming'oma
• kuvuta kupuma kapena kumeza
• kupweteka kwa mikono, kumbuyo, chifuwa, khosi, kapena nsagwada
• mawu odekha kapena ovuta
• chizungulire kapena kukomoka
• kufooka, dzanzi, kapena kulephera kusuntha mkono kapena mwendo
• kupweteka kwa mafupa
• pokodza mopweteka, pafupipafupi, kapena movutikira
• magazi mkodzo
• ludzu lokwanira
• kufooka
• pakamwa pouma
• nseru
• kusanza
• mpweya womwe umanunkhira zipatso
• kuchepa chikumbumtima
• mutu mwadzidzidzi
• kusawona bwino
• masomphenya amasintha
• zovuta kusuntha maso
• zikope zothothoka
• chisokonezo
• kugwidwa

Jakisoni wa Leuprolide atha kubweretsa kuchepa kwa kuchuluka kwa mafupa anu komwe kumatha kuwonjezera mwayi wamafupa osweka. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ndikupeza zomwe mungachite kuti muchepetse zoopsa izi.

Kwa ana omwe alandila jakisoni wa leuprolide (Lupron Depot-PED, Fensolvi) kuti atha msinkhu msanga, zizindikilo zatsopano kapena zowonjezereka zakukula pogonana zitha kuchitika m'masabata angapo oyamba achipatala. Atsikana omwe amalandira jakisoni wa leuprolide (Lupron Depot-PED) chifukwa chotha msinkhu, kuyamba kusamba kapena kuwona (kutuluka magazi kumaliseche) kumatha kuchitika m'miyezi iwiri yoyambirira yothandizidwa. Ngati magazi akupitirira kupitirira mwezi wachiwiri, itanani dokotala wanu.

Kubayira kwa Leuprolide kungayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu ndikutenga miyezo inayake kuti muwone momwe thupi lanu lingayankhire jakisoni wa leuprolide. Magazi anu a shuga ndi hemoglobin (HbA1c) yama glycosylated amathanso kuwunikidwa pafupipafupi.

Funsani wamankhwala wanu mafunso aliwonse omwe ali nawo okhudza jakisoni wa leuprolide.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Eligard^®
• Fensolvi^®
• Lupron^®
• Lupron Depot^®
• Lupron Depot-PED^®
• Lupaneta Pack^® (monga chinthu chophatikizira chomwe chili ndi Leurprolide, Norethindrone)

• Leuprorelin Acetate