Jekeseni wa Fludarabine

Zamkati

• Asanalandire jakisoni wa fludarabine,
• Jekeseni wa Fludarabine imatha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo:

Jekeseni wa Fludarabine uyenera kuperekedwa moyang'aniridwa ndi dokotala yemwe amadziwa bwino kupereka mankhwala a chemotherapy a khansa.

Jekeseni wa Fludarabine ungayambitse kuchepa kwa maselo amwazi omwe amapangidwa ndi mafupa. Kuchepetsa kumeneku kumatha kukupangitsani kukhala ndi zizindikiritso zowopsa ndipo kumawonjezera chiopsezo chanu chokhala ndi matenda akulu kapena owopsa. Dokotala wanu akhoza kukupatsani mankhwala ena kuti muchepetse chiopsezo choti mungakhale ndi matenda akulu mukamalandira chithandizo. Uzani dokotala wanu ngati mwakhalapo ndi mtundu wochepa kwambiri wamaselo amwazi m'magazi anu kapena vuto lililonse lomwe limakhudza chitetezo chanu chamthupi komanso ngati mwadwalapo matenda chifukwa ma cell am'magazi anu anali ochepa kwambiri. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: kupuma movutikira; kugunda kwamtima; mutu; chizungulire; khungu lotumbululuka; kutopa kwambiri; kutuluka mwachilendo kapena kuvulala; wakuda, wodikira, kapena chopondapo chamagazi; kusanza komwe kuli kwamagazi kapena komwe kumawoneka ngati malo a khofi; ndi malungo, kuzizira, chifuwa, zilonda zapakhosi, zovuta, zopweteka, kapena kukodza pafupipafupi, kapena zizindikilo zina za matenda.

Jekeseni wa Fludarabine amathanso kuwononga dongosolo lamanjenje. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo: khunyu, kusokonezeka, chisokonezo, ndi kukomoka (kutaya chidziwitso kwakanthawi).

Jekeseni wa Fludarabine imatha kubweretsa zoopsa kapena zoopsa zomwe thupi limagunda ndikuwononga maselo ake amwazi. Uzani dokotala wanu ngati mudakhalapo ndi izi mutalandira fludarabine m'mbuyomu. Ngati mukumane ndi izi, itanani dokotala wanu mwachangu: mkodzo wakuda, khungu lachikaso, timadontho tofiira tofiira kapena tofiirira pakhungu, magazi a m'mphuno, kutuluka magazi msambo, magazi mkodzo, kutsokomola magazi, kapena kupuma movutikira chifukwa chakutuluka magazi kummero.

Pa kafukufuku wamankhwala, anthu omwe ali ndi khansa ya m'magazi ya lymphocytic omwe amagwiritsa ntchito jakisoni wa fludarabine limodzi ndi pentostatin (Nipent) anali pachiwopsezo chotenga mapapo. Nthawi zina, kuwonongeka kwamapapu kumeneku kumapha. Chifukwa chake, dokotala wanu sangakupatseni jakisoni wa fludarabine kuti apatsidwe pamodzi ndi pentostatin (Nipent).

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti muwone momwe thupi lanu limayankhira jakisoni wa fludarabine.

Lankhulani ndi dokotala wanu za kuopsa kolandila jekeseni wa fludarabine.

Jekeseni wa Fludarabine amagwiritsidwa ntchito pochiza khansa ya m'magazi (CLL; mtundu wa khansa yamagazi oyera) mwa akulu omwe adalandira kale mankhwala osachepera amodzi ndipo sanakhale bwino. Jekeseni wa Fludarabine ili mgulu la mankhwala otchedwa purine analogs. Zimagwira pochepetsa kapena kuletsa kukula kwa maselo a khansa mthupi lanu.

Jekeseni wa Fludarabine umabwera ngati ufa woti uwonjezeredwe pamadzimadzi ndikubayidwa mphindi 30 mkati mwa mtsempha (ndi mtsempha) ndi dokotala kapena namwino kuofesi yazachipatala kapena kuchipatala cha odwala kuchipatala. Nthawi zambiri amabayidwa kamodzi patsiku kwa masiku 5 motsatizana. Nthawi yamankhwala iyi imatchedwa kuzungulira, ndipo kuzungulira kumatha kubwereza masiku 28 aliwonse kwa nthawi zingapo.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu kapena kusintha mlingo wanu ngati mukukumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira jekeseni wa fludarabine.

Jekeseni wa Fludarabine imagwiritsidwanso ntchito pochiza non-Hodgkin's lymphoma (NHL; khansa yomwe imayambira mumtundu wama cell oyera omwe nthawi zambiri amalimbana ndi matenda) ndi mycosis fungoides (mtundu wa lymphoma womwe umakhudza khungu). Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa fludarabine,

• auzeni adotolo ndi azachipatala ngati muli ndi matupi awo sagwirizana ndi fludarabine, mankhwala aliwonse, kapena china chilichonse mu jakisoni wa fludarabine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe adatchulidwa mu gawo LOFUNIKA CHENJEZO kapena cytarabine (Cytosar-U, DepoCyt). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mwakhalapo ndi matenda a impso Komanso muuzeni dokotala zamankhwala ena onse omwe mwalandira ndi ngati mwalandirapo mankhwala a radiation (chithandizo cha khansa chomwe chimagwiritsa ntchito mafunde amphamvu kwambiri kupha ma cell a khansa. ). Musanalandire chemotherapy kapena radiation radiation mtsogolo, uzani dokotala kuti mwalandira mankhwala a fludarabine.
• muyenera kudziwa kuti jakisoni wa fludarabine itha kusokoneza nthawi yanthawi yakusamba mwa azimayi ndipo imatha kusiya kupanga umuna mwa amuna. Komabe, musaganize kuti inu kapena mnzanuyo simungakhale ndi pakati. Ngati muli ndi pakati kapena mukuyamwitsa, muyenera kuuza dokotala musanayambe kulandira mankhwalawa. Simuyenera kukonzekera kukhala ndi ana mukalandira jakisoni wa fludarabine kapena kwa miyezi isanu ndi umodzi mutalandira chithandizo. Gwiritsani ntchito njira yodalirika yolerera popewa kutenga pathupi panthawiyi. Lankhulani ndi dokotala wanu kuti mumve zambiri. Jekeseni wa Fludarabine itha kuvulaza mwana wosabadwayo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukulandira jakisoni wa fludarabine.
• muyenera kudziwa kuti jakisoni wa fludarabine imatha kubweretsa kutopa, kufooka, chisokonezo, kusokonezeka, kugwidwa, komanso kusintha kwa masomphenya. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• lankhulani ndi dokotala musanalandire katemera aliyense mukamamwa mankhwala a jekeseni wa fludarabine.
• muyenera kudziwa kuti mutha kukhala ndi vuto lalikulu kapena loopseza moyo ngati mukufuna kulandira magazi mukamalandira jekeseni wa fludarabine kapena nthawi iliyonse mukalandira chithandizo. Onetsetsani kuti muuze dokotala kuti mukulandira kapena mwalandira jakisoni wa fludarabine musanalandire magazi.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jekeseni wa Fludarabine imatha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kusowa chilakolako
• nseru
• kusanza
• kudzimbidwa
• kutsegula m'mimba
• zilonda mkamwa
• kutayika tsitsi
• dzanzi, kutentha, kupweteka, kapena kumva kulasalasa m'manja, mikono, mapazi, kapena miyendo
• kupweteka kwa minofu kapena molumikizana
• mutu
• kukhumudwa
• mavuto ogona

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

• kupweteka pachifuwa kapena kusapeza bwino
• kuthamanga kapena kusakhazikika kwamtima
• kutaya kumva
• ululu m'mbali mwa thupi
• kutupa kwa mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
• zidzolo
• ming'oma
• kuvuta kupuma kapena kumeza
• khungu losenda kapena lotupa

Jekeseni wa Fludarabine imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• kuvulaza kapena kutuluka mwachilendo
• malungo, kuzizira, chifuwa, zilonda zapakhosi, kapena zizindikilo zina za matenda
• kuchedwa khungu
• chikomokere

Funsani dokotala wanu kapena wamankhwala ngati muli ndi mafunso okhudza jekeseni wa fludarabine.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Fludara^®

• 2-Fluoro-ara-A Monophosphate, 2-Fluoro-ara AMP, FAMP