Jekeseni wa Granisetron

Zamkati

• Musanagwiritse ntchito jakisoni wa granisetron,
• Jakisoni wa granisetron amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Jekeseni wotulutsidwa mwachangu wa Granisetron amagwiritsidwa ntchito popewa mseru ndi kusanza komwe kumayambitsidwa ndi chemotherapy ya khansa komanso kupewa ndi kuchiza nseru ndi kusanza zomwe zingachitike mutachitidwa opaleshoni. Jekeseni wa Granisetron wotulutsa nthawi yayitali amagwiritsidwa ntchito ndi mankhwala ena kuti apewe nseru ndi kusanza komwe kumayambitsidwa ndi chemotherapy ya khansa yomwe imatha kuchitika nthawi yomweyo kapena masiku angapo atalandira mankhwala a chemotherapy. Granisetron ali mgulu la mankhwala otchedwa 5-HT₃ otsutsana nawo. Zimagwira ntchito poletsa serotonin, chinthu chachilengedwe mthupi chomwe chimayambitsa nseru ndi kusanza.

Jekeseni wotulutsa pompopompo wa Granisetron umabwera ngati yankho (madzi) kuti alowemo kudzera m'mitsempha (mumtsempha) ndipo jakisoni wokulitsa wa granisetron amabwera ngati madzi olowetsedwa pansi pake (pansi pa khungu). Pofuna kupewa kunyansidwa ndi kusanza komwe kumayambitsidwa ndi chemotherapy ya khansa, ma granisetron amamasulidwa mwachangu komanso ma jekeseni otulutsa nthawi zambiri amaperekedwa ndi othandizira azaumoyo kuchipatala kapena kuchipatala pasanathe mphindi 30 chemotherapy isanayambe. Pofuna kupewa kunyansidwa ndi kusanza komwe kumachitika chifukwa cha opareshoni, granisetron yotulutsidwa mwachangu nthawi zambiri imaperekedwa nthawi ya opaleshoni. Pofuna kuchiza nseru ndi kusanza komwe kumachitika chifukwa cha opareshoni, granisetron imaperekedwa msanga mseru ndikusanza kumachitika.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa granisetron,

• uzani dokotala wanu komanso wamankhwala ngati mukugwirizana ndi granisetron, alosetron (Lotronex), dolasetron (Anzemet), ondansetron (Zofran, Zuplenz), palonosetron (Aloxi, ku Akynzeo), mankhwala ena aliwonse, kapena chilichonse mwazinthu zopangira jekeseni ya granisetron. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: amiodarone (Cordarone, Nexterone, Pacerone); azithromycin (Zithromax), chlorpromazine, citalopram (Celexa); clarithromycin (Biaxin, mu Prevpac); erythromycin (EES, ERYC, Erythrocin, ena); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Subsys); ketoconazole (Nizoral); lifiyamu (Lithobid); mankhwala a mavuto amtima; mankhwala ochizira migraines monga almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, ku Treximet), ndi zolmitriptan (Zomig); mirtazapine (Remeron); monoamine oxidase (MAO) inhibitors kuphatikiza isocarboxazid (Marplan), methylene buluu; linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate); moxifloxacin (Avelox); pimozide (Orap); phenobarbital; serotonin reuptake inhibitors (SSRIs) monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, ku Symbyax, ena), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), ndi sertraline (Zoloft) ; mankhwala a serotonin-norepinephrine reuptake inhibitors (SNRI) a desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), ndi venlafaxine; sotalol (Betapace, Sorine); thioridazine; ndi tramadol (Conzip, Ultram, mu Ultracet). Ngati mukulandira jakisoni wokulutsani, uzani dokotala wanu ngati mukumwa mankhwala opha tizilombo ('opopera magazi') monga warfarin (Coumadin, Jantoven); mankhwala antiplatelet monga cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, mu Aggrenox), prasugrel (Effient), kapena ticlopidine. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala pazotsatira. Mankhwala ena ambiri amathanso kulumikizana ndi granisetron, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu ngati mwangoyamba kumene kuchitidwa opaleshoni ya m'mimba kapena kudzimbidwa. Komanso, uzani dokotala ngati inu kapena wina aliyense m'banja mwanu adakhalapo kapena adakhalapo ndi matenda a QT (zomwe zimawonjezera chiopsezo chokhala ndi kugunda kwamtima kosasunthika komwe kumatha kukomoka kapena kufa mwadzidzidzi), mtundu wina wamgwirizano wamtima wosasinthasintha kapena vuto la mtima, Kusalinganika kwa electrolyte, kapena impso kapena matenda amtima.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa granisetron, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jakisoni wa granisetron amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kudzimbidwa
• kuvuta kugona kapena kugona

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi:

• ming'oma
• zidzolo
• kuchapa
• kuyabwa
• kuvuta kupuma kapena kumeza
• kupuma movutikira
• kutupa kwa maso, nkhope, pakamwa, lilime, kapena pakhosi
• kupweteka pachifuwa
• kufiira kwa malo obayira jekeseni, kutupa, kapena kutentha kapena opanda malungo (pa jekeseni womasulidwa)
• jekeseni wamagazi magazi, kuvulala, kapena kupweteka (kwa jekeseni womasulidwa)
• kupweteka kwa m'mimba kapena kutupa
• chizungulire, mutu wopepuka, ndi kukomoka
• kusintha kwa kugunda kwa mtima
• mukubwadamuka, kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe). kusintha kwa malingaliro, kapena kukomoka (kutaya chidziwitso)
• kunjenjemera, kutayika kwa mgwirizano, kapena kuuma kapena kupindika kwa minofu
• malungo
• thukuta kwambiri
• chisokonezo
• nseru, kusanza, ndi kutsegula m'mimba
• kugwidwa

Jakisoni wa Granisetron amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• mutu

Sungani maimidwe onse ndi dokotala wanu.

Musanayezetsedwe kwa labotale (makamaka yomwe imakhudza methylene buluu), uzani adotolo ndi ogwira nawo ntchito kuti mukulandira jakisoni wa granisetron.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Sustol^®