Pambuyo pa Kuzindikira kwa AHP: Mwachidule cha Acute Hepatic Porphyria

Zamkati

• Matendawa
• Kuwunika zizindikiro
• Chithandizo
• Mayesero azachipatala
• Kuthetsa ziwopsezo
• Kusintha moyo
• Kupsinjika ndi thanzi lamaganizidwe
• Kuyesedwa kwachibadwa
• Tengera kwina

Pachimake hepatic porphyria (AHP) imaphatikizapo kutayika kwa mapuloteni a heme omwe amathandizira kupanga maselo ofiira athanzi. Zinthu zina zambiri zimagawana zizindikilo za matendawa, chifukwa chake kuyesa kwa AHP kumatha kutenga nthawi.

Dokotala wanu adzakuuzani kuti muli ndi AHP pambuyo poyesa magazi, mkodzo, komanso majini. Mukazindikira, chithandizo ndi kasamalidwe kanu kangayambike.

Kuzindikira kwa AHP kumatha kubweretsa mafunso ambiri. Mutha kudabwa za njira zanu zamankhwala ndi zina zomwe mungachite kuti muteteze zamtsogolo.

Phunzirani zambiri za zomwe inu ndi dokotala mungachite mutatsata matenda a AHP.

Matendawa

Zimakhala zachilendo kuti AHP ikhale yoyamba chifukwa cha kuchepa kwake komanso zizindikiro zazikulu. Gulu lanu lazachipatala lidzagwiritsa ntchito mayesero angapo kuti liwone ngati ali ndi matendawa ndikuwona ngati ali ndi vuto lodana ndi porphyria.

Mayeso ndi awa:

• kuyesa kwamkodzo kwa porphobilinogen (PBG)
• kujambulidwa kwa tomography (CT)
• X-ray pachifuwa
• Echocardiogram (EKG)
• kuwerengera magazi kwathunthu (CBC)
• kuyesa majini

Kuyesedwa kwa mkodzo wa PBG nthawi zambiri kumawoneka kuti ndikofunikira kwambiri chifukwa mkodzo PBG umakwezedwa nthawi yayikulu.

Matendawa nthawi zambiri amatsimikiziridwa ndi kuyesa kwa majini kwa munthu amene akuyesedwa komanso abale ake.

Kuwunika zizindikiro

Chimodzi mwadongosolo labwino la kasamalidwe ka AHP ndikumvetsetsa zizindikiritso. Izi zikuthandizani kudziwa nthawi yoyenera kuchitapo kanthu isanatenge zovuta zina.

Malinga ndi National Institutes of Health, kupweteka m'mimba ndichizindikiro chodziwika bwino cha kuukira kwa AHP. Ululu ukhoza kufalikira mbali zina za thupi lanu, monga:

• mikono
• miyendo
• kubwerera

Kuukira kwa AHP kungayambitsenso:

• kupuma movutikira, monga kupuma kapena kumva pakhosi panu
• kudzimbidwa
• mkodzo wamtundu wakuda
• kuvuta kukodza
• kuthamanga kwa magazi
• kuchuluka kwa kugunda kwa mtima kapena kugunda kwamtima koonekera
• nseru
• ludzu lomwe limasandulika kukhala kusowa kwa madzi m'thupi
• khunyu kapena kuyerekezera zinthu m'maganizo
• kusanza
• minofu yofooka

Itanani dokotala wanu ngati mukumane ndi izi. Dokotala wanu angakutsogolereni kuchipatala kuti mukalandire chithandizo.

Chithandizo

Njira zodzitetezera ndizofunikira kuti muchepetse ziwopsezo za AHP ndikukhalitsa moyo wanu wabwino. Dokotala wanu angakupatseni mtundu wina wa heme wotchedwa hemin, womwe ungathandize thupi lanu kupanga mapuloteni a hemoglobin.

Heme amapezeka ngati mankhwala akumwa, koma amathanso kuperekedwa ngati jakisoni. Ma Hemin IV amagwiritsidwa ntchito mzipatala nthawi ya AHP.

Malingana ndi momwe mulili, adokotala angavomereze izi:

• Mavitamini a shuga atha kupatsidwa pakamwa ngati mapiritsi a shuga kapena kudzera mu minyewa kuthandiza thupi lanu kukhala ndi shuga wokwanira kupanga maselo ofiira.
• Gonadotropin-yotulutsa hormone agonist Ndi mankhwala omwe amagwiritsidwa ntchito kwa azimayi omwe amataya heme pakusamba.
• Phlebotomy ndi njira yochotsera magazi yomwe imagwiritsidwa ntchito pochotsa chitsulo chochuluka mthupi.
• Mankhwala a Gene monga givosiran, yomwe mu Novembala 2019.

Givosiran adatsimikiza kuti achepetse kuchuluka kwa zopangidwa ndi poizoni zomwe zimapangidwa m'chiwindi, zomwe zimapangitsa kuti AHP isamawonongeke pang'ono.

Kusankha mankhwala oyenera kumafunikanso kuyezetsa magazi pafupipafupi. Dokotala wanu amatha kuyeza heme, chitsulo, ndi zinthu zina kuti awone ngati chithandizo chanu chikugwira ntchito kapena ngati mungafune kusintha zina ndi zina panjira yanu ya AHP.

Mayesero azachipatala

Ofufuza akuyesera kuzindikira ndikupanga mankhwala atsopano monga givosiran kuti athetse vutoli. Mutha kulingalira kufunsa adotolo za mayesero aliwonse azachipatala omwe angakhale oyenera kwa inu.

Mayeserowa atha kupereka chithandizo chaulere, komanso kulipidwa. Muthanso kuphunzira zambiri kudzera ku ClinicalTrials.gov.

Kuthetsa ziwopsezo

Kusamalira AHP nthawi zambiri kumadalira kuyang'anira zoyambitsa. Koma chiwembucho chikachitika, ndikofunikira kupeza chithandizo chamankhwala kuti muchepetse ululu.

Kuukira kwa AHP nthawi zambiri kumafuna kuchipatala. Kumeneku mungapatsidwe heme kudzera m'mitsempha poyang'aniridwa ngati muli ndi vuto la impso kapena chiwindi.

Sikuti ziwonetsero zonse za AHP zimafunikira kupita kuchipatala. Komabe, kupweteka kwambiri kapena zizindikilo zazikulu zimafunikira chisamaliro chadzidzidzi.

Dokotala wanu akhoza kukupatsani mankhwala, monga beta-blockers a kuthamanga kwa magazi, antiemetic wosanza, kapena mankhwala othandizira kupweteka, kuti athetse matenda

Kusintha moyo

Ngakhale palibe dongosolo lachikhalidwe lomwe lingapangitse AHP kuchoka, pali zina zomwe zimayambitsa AHP zomwe muyenera kudziwa.

Izi zikuphatikiza:

• kudya mapuloteni ambiri
• kusala kudya
• kudya kwambiri chitsulo
• mankhwala obwezeretsa mahomoni
• chakudya chochepa cha kalori
• Zakudya zochepa za carb
• zowonjezera zitsulo (OTC kapena mankhwala)
• kusuta

Kupsinjika ndi thanzi lamaganizidwe

Kukhala ndi matenda osachiritsika ngati AHP kumatha kukhala kopanikiza, makamaka popeza ndi matenda osowa. Ndikofunika kuti muchepetse nkhawa zanu momwe mungathere.

Ngakhale kupsinjika mtima sikomwe kumayambitsa kuukira kwa AHP, kumatha kukulitsa chiopsezo chanu.

Ma Porphyrias amathanso kubweretsa zovuta zina, monga:

• nkhawa
• kukhumudwa
• chisokonezo
• phobias

Onetsetsani kuti othandizira anu azaumoyo akusinthidwa pazizindikiro zilizonse zamatenda omwe mwina mukukumana nawo, monga:

• mantha
• kusowa tulo
• kupsa mtima
• kutaya chidwi ndi zochitika zanu zanthawi zonse

Zizindikiro zoterezi zitha kutchulidwa ngati gawo lamaphunziro anu azaumoyo.

Simuli nokha polimbana ndi zizindikilo zanu za AHP, kotero kufikira ena kumatha kukhala kothandiza kwambiri.

Kuyesedwa kwachibadwa

Ngati mwapezeka ndi AHP, dokotala wanu angakulimbikitseni kuyesa kwa majini kwa ana anu kapena abale anu ena.

Dokotala wanu amatha kuyang'ana michere m'chiwindi kuti akuthandizeni kudziwa ngati abale anu ali pachiwopsezo cha AHP.

Kuyesedwa kwa majini sikungalepheretse kuyambika kwa AHP, koma kumatha kuthandiza okondedwa anu kuti ayang'anire kukulitsa zizindikilo zokhudzana nazo.

Tengera kwina

Kupeza matenda a AHP kungakhale kovuta poyamba, koma dokotala wanu alipo kuti ayankhe mafunso anu onse ndikuonetsetsa kuti mulandila chithandizo chabwino kwambiri.

Maganizo a anthu omwe ali ndi AHP ndiabwino. Kuwongolera zizindikilo zanu ndi chithandizo chamankhwala ndikusintha kwa moyo wanu, kumatha kukuthandizani kuti muzichita zochitika zanu za tsiku ndi tsiku ndi zochepa.