Kodi mapiritsi a Alli Zakudya (Orlistat) Amagwira Ntchito? Kubwereza Kotsimikizika

Zamkati

• Kodi Alli (Orlistat) ndi Chiyani?
• Kodi Alli Amagwira Ntchito Motani?
• Alli Atha Kukuthandizani Kuchepetsa Kuchepetsa Kunenepa
• Kafukufuku Wambiri
• Kodi Mapiritsi A Alli Ali Ndi Ubwino Wina Wathanzi?
• Zotsatira zoyipa, Mlingo ndi Momwe Mungagwiritsire Ntchito
• Kodi Muyesetse Alli?

Kuchepetsa thupi kumakhala kovuta kwambiri.

Kafukufuku wina akuwonetsa kuti 85% ya anthu amalephera kugwiritsa ntchito njira zodziwikira (1).

Izi zimapangitsa anthu ambiri kufunafuna njira zina, monga mapiritsi azakudya, kuti awathandize.

Alli ndi umodzi mwa mapiritsi azakudya zotere, koma ndi mankhwala opangira mankhwala osati chowonjezera chazomera.

Mankhwalawa amachepetsa kuchuluka kwa mafuta omwe matupi athu amatenga, omwe amachepetsa kudya kwa kalori ndikupangitsa kuti muchepetse thupi.

Uku ndikuwunikanso mwatsatanetsatane mapiritsi a Alli: zomwe ali, momwe amagwirira ntchito, komanso ngati ali oyenera inu.

Kodi Alli (Orlistat) ndi Chiyani?

Alli ndiwosagwiritsa ntchito mankhwala osokoneza bongo otchedwa orlistat.

Mtundu wokhawo wamankhwala umatchedwa Xenical, womwe umakhala ndi mulingo wokwera. Mapiritsi a Alli ali ndi 60 mg ya orlistat, pomwe mapiritsi a Xenical amakhala ndi 120 mg.

Mankhwalawa adavomerezedwa koyamba ndi a FDA mu 1999. Nthawi zambiri amapatsidwa malangizo othandizira kuti azitha kunenepa kwambiri kwakanthawi yayitali, limodzi ndi zakudya zonenepa kwambiri, zoperewera kalori.

Alli ndi mtundu wa orlistat, mankhwala omwe amagwiritsidwa ntchito kuthana ndi kunenepa kwambiri. Ikupezekanso mwa mankhwala monga Xenical.

Kodi Alli Amagwira Ntchito Motani?

Alli amagwira ntchito poletsa thupi kuti lisamwe mafuta azakudya.

Makamaka, imatchinga ma enzyme m'matumbo otchedwa lipase.

Lipase ndilofunikira pakupukusa mafuta omwe timadya. Zimathandizira kuwononga mafuta kukhala mafuta aulere omwe amatha kutengedwa ndi thupi.

Popanda enzyme iyi, mafuta azakudya amadutsa chimbudzi kenako amachotsedwa mthupi.

Monga lipase-inhibitor, Alli adawonetsedwa kuti amachepetsa kuyamwa kwa mafuta azakudya pafupifupi 30% ().

Chifukwa mafuta amadzimadzi amakhala ndi ma calories ambiri, izi zimabweretsa kuchepa kwa ma calories m'thupi, zomwe zimapangitsa kuti muchepetse thupi.

Alli amasokoneza chimbudzi cha mafuta azakudya ndikuletsa pafupifupi 30% yamafuta kuti asatengeke. Izi zimabweretsa kuchepa kwathunthu kwa kalori.

Alli Atha Kukuthandizani Kuchepetsa Kuchepetsa Kunenepa

Kafukufuku wochuluka wa anthu wachitidwa pa orlistat, mankhwala opangira mapiritsi a Alli.

Chodziwika bwino kwambiri ndi kafukufuku waku Sweden XENDOS, yemwe adaphatikizira anthu 3,305 onenepa kwambiri ndipo adakhala zaka 4 (3).

Panali magulu awiri mu phunziroli. Mmodzi adatenga 120 mg ya orlistat, katatu tsiku lililonse, pomwe gulu linalo lidatenga placebo.

Onse omwe adatenga nawo gawo adauzidwa kuti azidya zopatsa mphamvu zochepa 800 patsiku, ndikuchepetsa mafuta azakudya mpaka 30% yama calories. Amalimbikitsidwanso kuyenda masiku onse.

Chithunzichi chikuwonetsa kusintha kwakulemera m'magulu awiriwa pazaka 4 (3):

M'chaka choyamba, ochepera omwe anali m'gulu la orlistat anali mapaundi 23.3 (10.6 kg), pomwe gulu la placebo lidangotsika makilogalamu 6.2.

Monga tawonera pa graph, panali kulemera kwakukulu m'magulu onse pazaka zitatu zotsalazo. Odwala omwe amathandizidwa ndi Orlistat adatsika ndi mapaundi 12.8 (5.8 kg), poyerekeza ndi 6.6 mapaundi (3.0 kg) mwa omwe amalandira malowa.

Malinga ndi kafukufukuyu, orlistat kuphatikiza zakudya ndi masewera olimbitsa thupi zitha kukupangitsani kuti muchepetse kuwirikiza kawiri kuposa zakudya ndi masewera olimbitsa thupi nokha.

Kafukufuku Wambiri

Malinga ndi kafukufuku waposachedwa, kuchepa kwa miyezi 12 kwa achikulire omwe amatenga orlistat ndi pafupifupi 7.5 lbs (3.4 kg) kuposa placebo ().

Izi zikufikira ku 3.1% ya kulemera koyamba, zomwe sizosangalatsa kwenikweni. Zikuwonekeranso kuti kulemera kumayambiranso pang'onopang'ono pambuyo pa chaka choyamba chamankhwala.

Chosangalatsa ndichakuti kafukufuku wina adawonetsa kuti zakudya zopanda mafuta ochepa kwambiri zimathandizanso ngati ma orlistat komanso zakudya zamafuta ochepa kuphatikiza ().

Alli / orlistat ndi mankhwala ochepetsa anti-kunenepa kwambiri, omwe amachepetsa kwambiri miyezi 12 kukhala 3.4 kg (7.5 lbs) wamkulu kuposa placebo.

Kodi Mapiritsi A Alli Ali Ndi Ubwino Wina Wathanzi?

Alli adalumikizidwanso ndi maubwino ena angapo azaumoyo, mwina chifukwa cha kuchepa kwa thupi.

• Kuchepetsa mtundu wa 2 matenda ashuga: Pakafukufuku wa XENDOS, kugwiritsa ntchito orlistat zaka 4 kunachepetsa chiopsezo chokhala ndi matenda a shuga amtundu wa 2 ndi 37% (3).
• Kuchepetsa kuthamanga kwa magazi: Kafukufuku akuwonetsa kuti Alli atha kuchepetsa kuthamanga kwa magazi (,).
• Kuchepetsa kwathunthu- ndi LDL-cholesterol: Kafukufuku akuwonetsa kuti Alli atha kukopa ma cholesterol (,).

Kugwiritsa ntchito Alli kwa nthawi yayitali kumachepetsa chiopsezo cha mtundu wachiwiri wa shuga ndikuthandizira kuteteza matenda amtima.

Zotsatira zoyipa, Mlingo ndi Momwe Mungagwiritsire Ntchito

Mapiritsi azakudya a Alli ali ndi zovuta zina zolembedwa zomwe ziyenera kuzindikiridwa ().

Pamene amaletsa kuyamwa kwa mafuta, kupezeka kwa mafuta osagwiritsidwa ntchito m'matumbo kumatha kuyambitsa matenda am'mimba, monga kupweteka m'mimba, kutsegula m'mimba komanso kupsa mtima.

Anthu ena amakhalanso ndi vuto lodzitchinjiriza komanso kutayirira, chopondapo mafuta.

Kupitiliza kugwiritsa ntchito Alli kumatha kusokonezanso kuyamwa kwa michere yosungunuka mafuta monga mavitamini A, D, E ndi K.

Pachifukwa ichi, kumwa multivitamin limodzi ndi chithandizo ndikulimbikitsidwa.

Alli amathanso kusokoneza kuyamwa kwamankhwala ena, ndipo milandu ingapo ya kulephera kwa chiwindi ndi poyizoni wa impso akuti.

Anthu omwe akumwa mankhwala kapena ali ndi mtundu wina uliwonse wamankhwala ayenera kufunsa adokotala asanamwe mapiritsi a Alli.

Kutengera ndi kuchuluka kwakanthawi kwakanthawi komwe kulipo, malangizo ambiri azachipatala amalimbikitsa kuti Alli asagwiritsidwe ntchito mosalekeza kwa miyezi yoposa 24.

Mulingo woyenera womwe umagwiritsidwa ntchito m'maphunzirowa ndi 120 mg, katatu patsiku.

Mapiritsi a Alli ali ndi zovuta zambiri. Amatha kubweretsa zovuta m'mimba ndi kuchepa kwa michere, komanso amathanso kusokoneza mankhwala ena. Mlingo wophunziridwa bwino kwambiri ndi 120 mg, katatu patsiku.

Kodi Muyesetse Alli?

Mapiritsi azakudya a Alli ndi ena mwazithandizo zochepa zochepa zomwe zimagwira ntchito pamlingo winawake. Komabe, zotsatira zake sizabwino monga momwe anthu ambiri amafunira.

Pomwepo, mutha kuchepa pang'ono, koma pokhapokha kuphatikiza ndi kuchepetsa thupi zakudya ndi masewera olimbitsa thupi.

Kuphatikiza apo, zopindulitsa pakuchepetsa thupi zimayenera kuyezedwa ndi zovuta zoyambitsa vuto lakugaya chakudya komanso kuperewera kwa michere.

Popanda kutchula, muyeneranso kudya zakudya zopanda mafuta, zomwe sizosangalatsa anthu ambiri.

Ngati mukufunitsitsadi kuchepa thupi ndipo sungani, ndiye kudya ma protein ambiri ndi ma carbs ochepa ndi njira yothandiza komanso yokhazikika.