Mlembi: Marcus Baldwin
Tsiku La Chilengedwe: 19 Kuni 2021
Sinthani Tsiku: 15 Novembala 2024
Anonim
Kuyesa kwa Alpha-Fetoprotein (AFP) - Mankhwala
Kuyesa kwa Alpha-Fetoprotein (AFP) - Mankhwala

Zamkati

Kodi mayeso a alpha-fetoprotein (AFP) ndi ati?

Alpha-fetoprotein (AFP) ndi mapuloteni omwe amapangidwa m'chiwindi cha mwana wosabadwa. Pakukula kwa mwana, AFP ina imadutsa mu placenta ndikulowa m'magazi a mayi. Kuyezetsa kwa AFP kumayesa kuchuluka kwa AFP mwa amayi apakati pa trimester yachiwiri yapakati. Kuchuluka kapena kuchepa kwambiri kwa AFP m'magazi a mayi kumatha kukhala chizindikiro cha chilema chobadwa kapena vuto lina. Izi zikuphatikiza:

  • Matenda a neural tube, vuto lalikulu lomwe limayambitsa kukula kwachilendo kwa mwana wakhanda yemwe akutukuka komanso / kapena msana
  • Down syndrome, matenda amtundu womwe amachititsa kupunduka kwakuchenjera ndikuchedwa kukula
  • Amapasa kapena kubadwa kangapo, chifukwa mwana wopitilira mmodzi akupanga AFP
  • Kuwerengera molakwika tsiku, chifukwa kuchuluka kwa AFP kumasintha nthawi yapakati

Mayina ena: AFP Amayi; Serum AFP yamayi; Chithunzi cha msAFP

Amagwiritsidwa ntchito yanji?

Kuyezetsa magazi kwa AFP kumagwiritsidwa ntchito poyang'ana mwana wosabadwa kuti akhale pachiwopsezo chobadwa ndi zovuta zamatenda, monga zotupa za neural tube kapena Down syndrome.


Chifukwa chiyani ndikufunika kuyesedwa kwa AFP?

American Pregnancy Association ikuti amayi onse apakati ayenera kupimidwa mayeso a AFP nthawi ina pakati pa sabata la 15 ndi la 20 la mimba. Mayesowa atha kulimbikitsidwa makamaka ngati:

  • Khalani ndi mbiri yabanja yolemala pobadwa
  • Ali ndi zaka 35 kapena kupitilira apo
  • Khalani ndi matenda ashuga

Kodi chimachitika ndi chiyani pa mayeso a AFP?

Katswiri wa zamankhwala adzatenga magazi kuchokera mumtsinje uli m'manja mwanu, pogwiritsa ntchito singano yaying'ono. Singanoyo italowetsedwa, magazi ang'onoang'ono amatengedwa mu chubu choyesera. Mutha kumva kuluma pang'ono singano ikamalowa kapena kutuluka. Izi nthawi zambiri zimatenga mphindi zosakwana zisanu.

Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?

Simukusowa kukonzekera kulikonse kwa mayeso a AFP.

Kodi pali zoopsa zilizonse pamayeso?

Pali chiopsezo chochepa kwambiri kwa inu kapena mwana wanu poyesedwa magazi a AFP. Mutha kukhala ndi ululu pang'ono kapena kuvulala pamalo pomwe singano idayikidwapo, koma zizindikiro zambiri zimatha msanga. Chiyeso china chotchedwa amniocentesis chimapereka chidziwitso chotsimikizika cha matenda a Down syndrome ndi zovuta zina zobereka, koma mayeserowa ali ndi chiopsezo chochepa chotenga padera.


Kodi zotsatirazi zikutanthauza chiyani?

Ngati zotsatira zanu zikuwonetsa kuposa AFP, zitha kutanthauza kuti mwana wanu ali ndi vuto la neural tube monga spina bifida, momwe mafupa a msana samatsekera mozungulira msana, kapena anencephaly, momwemo ubongo sukula bwino.

Ngati zotsatira zanu zikuwonetsa zocheperako kuposa milingo ya AFP, zitha kutanthauza kuti mwana wanu ali ndi vuto la majini monga Down syndrome, vuto lomwe limayambitsa mavuto anzeru ndi chitukuko.

Ngati milingo yanu ya AFP siili yachilendo, sizitanthauza kuti pali vuto ndi mwana wanu. Zitha kutanthauza kuti mukukhala ndi ana opitilira m'modzi kapena kuti tsiku lanu lolakwika ndi lolakwika. Muthanso kupeza zotsatira zabodza. Izi zikutanthauza kuti zotsatira zanu zikuwonetsa vuto, koma mwana wanu ndi wathanzi. Ngati zotsatira zanu zikuwonetsa kukwera kapena kutsika kwa AFP, mudzapeza mayeso ena kuti muthandizidwe.

Dziwani zambiri zamayeso a labotale, magawo owerengera, ndi zotsatira zakumvetsetsa.

Kodi pali china chilichonse chomwe ndiyenera kudziwa za mayeso a AFP?

Kuyesedwa kwa AFP nthawi zambiri kumakhala gawo la mayeso angapo obereka omwe amatchedwa mayimidwe angapo kapena mayeso atatu. Kuphatikiza pa AFP, kuyezetsa katatu kumaphatikizapo kuyesa kwa hCG, mahomoni opangidwa ndi placenta, ndi estriol, mtundu wa estrogen wopangidwa ndi mwana wosabadwa. Mayeserowa atha kuthandiza kuzindikira kuti Down syndrome ndi matenda ena amtundu.


Ngati muli pachiwopsezo chachikulu chokhala ndi mwana yemwe ali ndi zovuta zina zobadwa, woperekayo angalimbikitsenso kuyesedwa kwatsopano kotchedwa DNA yopanda ma cell (cfDNA). Uku kuyesa magazi komwe kumatha kuperekedwa koyambirira kwa 10th sabata la mimba. Ikhoza kuwonetsa imatha kuwonetsa ngati mwana wanu ali ndi mwayi waukulu wokhala ndi Down syndrome kapena matenda ena amtundu.

Zolemba

  1. American Pregnancy Association [Intaneti]. Irving (TX): Mgwirizano wa Amayi Achimereka; c2017. Kuwonetsetsa Kwa amayi a Serum Alpha-Fetoprotein (MSAFP) [kusinthidwa 2016 Sep 2; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein-screening
  2. American Pregnancy Association [Intaneti]. Irving (TX): Mgwirizano wa Amayi Achimereka; c2017. Kuyesa Kwazithunzi Zitatu [kusinthidwa 2016 Sep 2; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
  3. Manda JC, Miller KE, Ogulitsa AD. Kusanthula Kwamayi Kwa Amayi Ndi Mimba. Ndi Sing'anga Wodziwika [Internet]. 2002 Mar 1 [yotchulidwa 2017 Jun 5]; 65 (5): 915–921. Ipezeka kuchokera: https://www.aafp.org/afp/2002/0301/p915.html
  4. Johns Hopkins Medicine [Intaneti]. Johns Hopkins Mankhwala; Laibulale ya Zaumoyo: Mayeso Omwe Akakhala Ndi Mimba [otchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/pregnancy_and_childbirth/common_tests_during_pregnancy_85,p01241
  5. Kuyesa kwa Labu Paintaneti [Intaneti]. Washington DC: American Association for Clinical Chemistry; c2001–2019. Kuwonetsetsa Kwa Amayi Amayi, Second Trimester; [yasinthidwa 2019 Meyi 6; yatchulidwa 2019 Jun 4]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://labtestsonline.org/tests/maternal-serum-screening-second-trimester
  6. Kuyesa kwa Labu Paintaneti [Intaneti]. American Association for Chipatala Chemistry; c2001–2017. Zakumapeto: Spina Bifida [wotchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://labtestsonline.org/glossary/spina-bifida
  7. Merck Manual Consumer Version [Intaneti]. Kenilworth (NJ): Merck & Co. Inc. .; c2017. Kuyezetsa Matenda Oyembekezera [kusinthidwa 2017 Jun; yatchulidwa 2019 June 4]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: http://www.merckmanuals.com/home/women-s-health-issues/detection-of-genetic-disorders/prenatal-diagnostic-testing
  8. National Center for Advancing Translational Science / Genetic and Rare Diseases Information Center [Intaneti]. Gaithersburg (MD): Dipatimenti ya Zaumoyo ku United States; Zovuta Za Neural Tube [zosinthidwa 2013 Nov 6; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
  9. National Heart, Lung, ndi Blood Institute [Internet]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Kodi Kuopsa Kwa Kuyesedwa Kwa Magazi Ndi Chiyani? [yasinthidwa 2012 Jan 6; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 5]. Ipezeka kuchokera: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
  10. National Heart, Lung, ndi Blood Institute [Internet]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Zomwe Mungayembekezere Kuyesedwa kwa Magazi [kusinthidwa 2012 Jan 6; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://www.nhlbi.nih.gov/health-topics/blood-tests
  11. University of Rochester Medical Center [Intaneti]. Rochester (NY): Yunivesite ya Rochester Medical Center; c2017. Health Encyclopedia: Alpha-fetoprotein (AFP) [yotchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid;=P02426
  12. University of Rochester Medical Center [Intaneti]. Rochester (NY): Yunivesite ya Rochester Medical Center; c2017. Health Encyclopedia: Alpha-fetoprotein (Magazi) [otchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alpha_fetoprotein_maternal_blood
  13. UW Health [Intaneti]. Madison (WI): Zipatala za University of Wisconsin ndi Clinics Authority; c2017. Zambiri Zaumoyo: Alpha-Fetoprotein (AFP) m'magazi [yasinthidwa 2016 Jun 30; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 5]. Ipezeka kuchokera: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
  14. UW Health [Intaneti]. Madison (WI): Zipatala za University of Wisconsin ndi Clinics Authority; c2017. Zambiri Zaumoyo: Kuwonetsetsa katatu kapena Quad kwa Zofooka za Kubadwa [kusinthidwa 2016 Jun 30; yatchulidwa 2017 Jun 5]; [pafupifupi zowonetsera 5]. Ipezeka kuchokera: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-screening-test/ta7038.html#ta7038-sec

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