Kuchiza Migraines ndi Antidepressants

Zamkati

• Kodi mitundu yosiyanasiyana ndi iti?
• Kusankha serotonin reuptake inhibitors (SSRIs)
• Serotonin-norepinephrine reuptake inhibitors (SNRIs)
• Tricyclic antidepressants
• Monoamine oxidase inhibitors (MAOIs)
• Kodi antidepressants amapewa bwanji migraines?
• Kodi zotsatira zoyipa za antidepressants ndi ziti?
• Kodi mankhwala opatsirana pogonana ali otetezeka?
• Matenda a Serotonin
• Mfundo yofunika

Kodi antidepressants ndi chiyani?

Antidepressants ndi mankhwala omwe amathandizira kuthana ndi zipsinjo. Ambiri mwa iwo amasintha mtundu wamankhwala wotchedwa neurotransmitter. Izi zimanyamula mauthenga pakati pa ma cell muubongo wanu.

Ngakhale ali ndi dzina, antidepressants amatha kuthana ndi zovuta zosiyanasiyana kuphatikiza kukhumudwa, kuphatikiza:

• nkhawa ndi mantha
• mavuto a kudya
• kusowa tulo
• kupweteka kosalekeza
• kutentha

Ma anti-depressants amathanso kupewa migraines. Werengani kuti mudziwe zambiri.

Kodi mitundu yosiyanasiyana ndi iti?

Pali mitundu inayi yayikulu ya antidepressants:

Kusankha serotonin reuptake inhibitors (SSRIs)

SSRIs imakulitsa kuchuluka kwa neurotransmitter serotonin muubongo wanu. Madokotala nthawi zambiri amapereka izi koyamba chifukwa zimayambitsa zovuta zochepa.

Serotonin-norepinephrine reuptake inhibitors (SNRIs)

SNRIs imakulitsa kuchuluka kwa serotonin ndi norepinephrine muubongo wanu.

Tricyclic antidepressants

Mankhwalawa, omwe amadziwikanso kuti cyclic antidepressants, amawonjezera kuchuluka kwa serotonin ndi norepinephrine.

Monoamine oxidase inhibitors (MAOIs)

Serotonin, norepinephrine, ndi dopamine onse ndi monoamines. Thupi lanu mwachilengedwe limapanga enzyme yotchedwa monoamine oxidase yomwe imawawononga. MAOIs amagwira ntchito poletsa mavitaminiwa kuti asamagwiritse ntchito ma monoamine muubongo wanu.

MAOIs satchulidwanso chifukwa amayambitsa zovuta zina.

Kodi antidepressants amapewa bwanji migraines?

Akatswiri sadziwa chomwe chimayambitsa mutu waching'alang'ala. Malinga ndi Chipatala cha Mayo, kusalinganika kwa ma neurotransmitters kumatha kutengapo gawo. Maselo a Serotonin amathanso kutsika panthawi ya migraine. Izi zikhoza kufotokoza chifukwa chake mankhwala opatsirana pogonana amawoneka kuti amathandiza kupewa.

Tricyclic antidepressants ndi amodzi mwamankhwala omwe amaperekedwa kuti ateteze migraine. Komabe, kafukufuku yemwe adalipo kale anapeza kuti ma SSRI ndi ma SNRI amagwiranso ntchito chimodzimodzi. Izi ndizofunikira chifukwa ma SSRIs ndi ma SNRI amakonda kuyambitsa zovuta zochepa kuposa tricyclic antidepressants.

Ngakhale maphunziro omwe atchulidwa pamwambapa akulonjeza, olembawo akuwona kuti maphunziro ambiri akulu, owongoleredwa amafunikira kuti amvetsetse momwe antidepressants amakhudzira migraines.

Ngati mumalandira mutu waching'alang'ala womwe sunayankhidwe ndi mankhwala ena, funsani dokotala wanu za kuyesa mankhwala opatsirana pogonana. Kumbukirani kuti antidepressants amagwiritsidwa ntchito popewa mutu waching'alang'ala, osachiza omwe akuchita.

Kodi zotsatira zoyipa za antidepressants ndi ziti?

Ma anti-depressants amatha kuyambitsa zovuta zingapo. SSRIs nthawi zambiri imayambitsa zovuta zochepa, chifukwa chake dokotala angaganize zoyesa mtundu uwu poyamba.

Zotsatira zoyipa pamitundu yosiyanasiyana ya mankhwala opanikizika ndi monga:

• pakamwa pouma
• nseru
• manjenje
• kusakhazikika
• kusowa tulo
• mavuto azakugonana, monga kutha kwa erectile kapena kuchedwa kukodzera

Tricyclic antidepressants, kuphatikiza amitriptyline, zimatha kuyambitsa zovuta zina, monga:

• kusawona bwino
• kudzimbidwa
• akutsikira kuthamanga kwa magazi ataimirira
• kusunga kwamikodzo
• Kusinza

Zotsatira zoyipa zimasiyananso pakati pa mankhwala, ngakhale mwa mtundu womwewo wa antidepressant. Gwiritsani ntchito ndi dokotala wanu kuti musankhe mankhwala opatsirana omwe amapindulitsa kwambiri ndi zotsatira zochepa kwambiri. Muyenera kuyesa zingapo musanapeze zomwe zimagwira ntchito.

Kodi mankhwala opatsirana pogonana ali otetezeka?

Ma anti-depressants amakhala otetezeka. Komabe, kumwa mankhwala opatsirana pogonana kuti muchiritse mutu wa migraine kumawonedwa ngati kosagwiritsidwa ntchito. Izi zikutanthawuza kuti opanga mankhwala oponderezana sanayesenso mayesero ofanana omwewo kuti ateteze ndi kugwiritsidwa ntchito pochiza mutu waching'alang'ala. Madokotala ambiri samapereka mankhwala kuti azigwiritsidwa ntchito pokhapokha ngati mankhwala ena alephera.

Dokotala wanu akhoza kukuthandizani kuti muone zaubwino komanso kuopsa kogwiritsa ntchito mankhwala opatsirana pogonana.

Mankhwala olepheretsa kupanikizika amathanso kuyanjana ndi mankhwala ena, chifukwa chake uzani dokotala wanu zamankhwala onse (OTC) ndi mankhwala omwe mumamwa. Izi zimaphatikizapo mavitamini ndi zowonjezera.

Muyeneranso kuuza dokotala ngati muli ndi:

• cholesterol yambiri
• mbiri ya matenda amtima
• chiopsezo chowonjezeka cha matenda a mtima kapena sitiroko
• khungu
• prostate wokulitsidwa

Matenda a Serotonin

Matenda a Serotonin ndi osowa koma oopsa omwe amapezeka pamene ma serotonin anu ali okwera kwambiri. Zimakonda kuchitika mukamamwa mankhwala opatsirana, makamaka MAOIs, ndi mankhwala ena, zowonjezera, kapena mankhwala osokoneza bongo omwe amachulukitsa kuchuluka kwanu kwa serotonin.

Musamwe mankhwala opatsirana pogonana ngati mutamwa kale mankhwala aliwonse a migraine:

• almotriptan (Axert)
• naratriptan (Amerge)
• sumatriptan (Imitrex)

Zinthu zina zomwe zingagwirizane ndi antidepressants ndikupangitsa matenda a serotonin ndi awa:

• dextromethorphan, chinthu chofala m'mankhwala ozizira a OTC ndi chifuwa
• zowonjezera zitsamba, kuphatikizapo ginseng ndi St. John's wort
• mankhwala ena opatsirana pogonana
• mankhwala osokoneza bongo, kuphatikizapo chisangalalo, cocaine, ndi amphetamines

Funsani chithandizo chamankhwala mwadzidzidzi ngati mungakumane ndi zovuta izi mukamamwa mankhwalawa:

• chisokonezo
• kutuluka kwa minofu ndi kunjenjemera
• kukhwimitsa minofu
• kunjenjemera
• kugunda kwamtima mwachangu
• malingaliro opitilira muyeso
• ana otayirira
• kugwidwa
• kusayankha

Mfundo yofunika

Chithandizo cha Migraine ndichimodzi mwazomwe anthu ambiri amagwiritsa ntchito mankhwala opatsirana pogonana. Ngakhale kuli kwakuti kwakukulu, maphunziro apamwamba amafunikira, kafukufuku amene alipo alipo akuwonetsa kuti mankhwala opatsirana amatha kukhala othandiza popewera ngati wina sakuyankha bwino mankhwala ena. Ngati mumalandira mutu waching'alang'ala womwe sukuyankhidwa ndi mankhwala ena, lankhulani ndi dokotala wanu za kuyesa mankhwala opatsirana pogonana.