Mayeso a Antimitochondrial Antibody (AMA)

Zamkati

• Chifukwa chiyani mayeso a AMA amalamulidwa?
• Kodi mayeso a AMA amayendetsedwa bwanji?
• Kodi kuopsa kwa mayeso a AMA ndi kotani?
• Kumvetsetsa zotsatira zanu za AMA

Kodi mayeso a antimitochondrial antibody ndi ati?

Mitochondria imapanga mphamvu kuti maselo mthupi lanu agwiritse ntchito. Zimakhala zofunikira pakuchita bwino kwa maselo onse.

Maantimitochondrial antibodies (AMAs) ndi chitsanzo cha kuyankha kwadzidzidzi komwe kumachitika thupi likamatsutsana ndi maselo ake, ziwalo zawo, ndi ziwalo zawo. Izi zikachitika, chitetezo cha mthupi chimagonjetsa thupi ngati kuti ndi matenda.

Chiyeso cha AMA chimazindikiritsa kuchuluka kwa ma antibodies m'magazi anu. Chiyesochi chimagwiritsidwa ntchito nthawi zambiri kuti chizindikire vuto lomwe limadziwika kuti primary biliary cholangitis (PBC), lomwe limadziwika kuti biliary cirrhosis.

Chifukwa chiyani mayeso a AMA amalamulidwa?

PBC imayambitsidwa ndi chitetezo cha mthupi pamagulu ang'onoang'ono amkati mwa chiwindi. Ma ducts owonongeka amayambitsa zipsera, zomwe zingayambitse chiwindi. Matendawa amabweretsanso chiopsezo chowopsa cha khansa ya chiwindi.

Zizindikiro za PBC zimaphatikizapo:

• kutopa
• khungu loyabwa
• chikasu cha khungu, kapena jaundice
• kupweteka kumtunda chakumanja
• kutupa, kapena edema ya manja ndi mapazi
• timadzi tambiri m'mimba
• pakamwa pouma ndi maso
• kuonda

Kuyezetsa kwa AMA kumagwiritsidwa ntchito kuthandizira kutsimikizira kuchipatala kwa PBC. Kuyesedwa kwachilendo kwa AMA kokha sikokwanira kuti munthu adziwe matendawa. Izi zikachitika, dokotala wanu atha kuyitanitsa mayeso ena, kuphatikiza izi:

Ma anti-nyukiliya (ANA): Odwala ena omwe ali ndi PBC amayesetsanso kukhala ndi ma antibodies awa.

Kutulutsa magazi: Mavitamini a alanine transaminase ndi aspartate transaminase ndi ofanana ndi chiwindi. Kuyesedwa kumazindikira kuchuluka kwakukwera, komwe nthawi zambiri kumakhala chizindikiro cha matenda a chiwindi.

Bilirubin: Ichi ndi chinthu chomwe thupi limatulutsa maselo ofiirawa akawonongeka. Imatulutsidwa kudzera mumkodzo ndi chopondapo. Kuchuluka kwambiri kumatha kuwonetsa matenda a chiwindi.

Albumin: Izi ndi zomanga thupi zopangidwa m'chiwindi. Magulu otsika amatha kuwonetsa kuwonongeka kwa chiwindi kapena matenda.

Mapuloteni othandizira C: Mayesowa amalamulidwa kuti azindikire matenda a lupus kapena mtima, koma amathanso kukhala chisonyezero cha zovuta zina zomwe zimangokhala zokha.

Ma anti-smooth muscle antibodies (ASMA): Mayesowa amaperekedwa limodzi ndi mayeso a ANA ndipo amathandiza pakuzindikira matenda a chiwindi.

Kuyezetsa magazi kwa AMA kungagwiritsidwenso ntchito kukuyang'anirani ngati muli ndi PBC ngati kuyezetsa magazi nthawi zonse kukuwonetsa kuti muli ndi alkaline phosphatase (ALP) kuposa masiku onse. Mulingo wokwera wa ALP ukhoza kukhala chizindikiro cha bile kapena matenda a ndulu.

Kodi mayeso a AMA amayendetsedwa bwanji?

Mayeso a AMA ndi kuyesa magazi. Namwino kapena waluso amakoka magazi anu kuchokera mumtsempha pafupi ndi chigongono kapena dzanja lanu. Magazi awa amatengedwa mu chubu ndi kutumizidwa ku labu kuti akawunikenso.

Dokotala wanu adzakufunsani kuti akufotokozereni zotsatira zanu zikadzapezeka.

Kodi kuopsa kwa mayeso a AMA ndi kotani?

Mutha kukhala ndi vuto lina mukalandira magazi. Pakhoza kukhala zowawa pamalo obowola panthawi yoyesa kapena itatha. Mwambiri, zowopsa zokoka magazi ndizochepa.

Zowopsa zomwe zingachitike ndi izi:

• kuvuta kupeza zitsanzo, zomwe zimabweretsa timitengo tingapo ta singano
• kutuluka magazi kwambiri pamalo osungilako singano
• kukomoka chifukwa chotaya magazi
• kudzikundikira kwa magazi pansi pa khungu, lotchedwa hematoma
• matenda pamalo opumira

Palibe kukonzekera kofunikira pakuyesaku.

Kumvetsetsa zotsatira zanu za AMA

Zotsatira zoyeserera zabwinobwino ndizosavomerezeka kwa AMA. AMA wabwino amatanthauza kuti pamakhala magazi omwe amapezeka m'magazi. Ngakhale kuyesa kwabwino kwa AMA nthawi zambiri kumalumikizidwa ndi PBC, itha kukhala yothandizanso pakudziyambitsa matenda a chiwindi, lupus, nyamakazi, ndi matenda olumikizirana. Ma antibodies awa ndi gawo limodzi lokha lomwe thupi limadzipangira lokha.

Ngati muli ndi zotsatira zabwino, mungafunike kuyesedwa kowonjezera kuti mutsimikizire matenda anu. Makamaka, dokotala wanu amatha kuyitanitsa chiwindi kuti atenge zitsanzo kuchokera pachiwindi. Dokotala wanu amathanso kuyitanitsa CT kapena MRI ya chiwindi chanu.