Funsani Katswiri: Dr. Amesh Adalja pa Chithandizo Chatsopano cha Hepatitis C

Zamkati

• Kodi Hepatitis C ndi Chiyani, ndipo Imasiyana Bwanji ndi Mitundu Ina Ya Hepatitis?
• Kodi Njira Zothandizira Chithandizo Ndi Chiyani?
• Kodi Ndi Mitundu Yotani Ya Njira Zatsopano Zomwe Zikufalikira, Ndipo Zikuwoneka Zothandiza Motani?
• Kodi Mankhwala Atsopano Awa Akufanizirana Bwanji Ndi Mankhwala Ochiritsika?
• Kodi Odwala Amayenera Kupanga Zisankho Zawo Motani?

Tidafunsa Dr. Amesh Adalja, katswiri wa matenda opatsirana ku University of Pittsburgh Medical Center, za zomwe adakumana nazo pochiza matenda a chiwindi a C (HCV). Katswiri pankhaniyi, a Dr. Adalja amapereka chithunzithunzi cha HCV, chithandizo chamankhwala wamba, ndi mankhwala atsopano osangalatsa omwe angasinthe masewerawa kwa odwala matenda a hepatitis C kulikonse.

Kodi Hepatitis C ndi Chiyani, ndipo Imasiyana Bwanji ndi Mitundu Ina Ya Hepatitis?

Hepatitis C ndi mtundu wa matenda a chiwindi omwe amasiyana ndi mitundu ina ya matenda a chiwindi chifukwa amakhala ndi chizolowezi chofika nthawi yayitali ndipo amatha kudwala chiwindi, khansa ya chiwindi, ndi mavuto ena amachitidwe. Imafalikira pafupifupi ku US ndipo ndiyomwe imayambitsa kusoweka chiwindi. Imafalikira kudzera pakuwonekera magazi monga kuthiridwa magazi (musanayese), kugwiritsa ntchito mankhwala a jakisoni ndipo kawirikawiri kudzera pakugonana. Hepatitis A ilibe mawonekedwe okhalitsa, ndi katemera wotetezedwa, imafalikira ndi njira yachinyengo, ndipo siyitsogolera ku chiwindi cha chiwindi ndi / kapena khansa. Hepatitis B, yomwe imayambitsanso magazi komanso imayambitsa matenda a chiwindi ndi khansa, ndi katemera wotetezedwa ndipo umafalikira mosavuta kudzera mukugonana komanso kuchokera kwa amayi kupita kwa ana awo panthawi yapakati komanso yobereka. Hepatitis E ili ngati hepatitis A koma, nthawi zambiri, imatha kukhala yayitali, komanso imafa kwambiri mwa amayi apakati.

Kodi Njira Zothandizira Chithandizo Ndi Chiyani?

Njira zochizira matenda a hepatitis C zimadalira mtundu wa chiwindi cha hepatitis C womwe umakhalapo. Pali mitundu isanu ndi umodzi yamatenda amtundu wa hepatitis C ndipo ina ndiosavuta kuchiza kuposa ena. Kawirikawiri, chithandizo cha matenda a chiwindi a C chimaphatikizapo kuphatikiza mankhwala awiri kapena atatu, kuphatikiza interferon, omwe amapatsidwa milungu 12.

Kodi Ndi Mitundu Yotani Ya Njira Zatsopano Zomwe Zikufalikira, Ndipo Zikuwoneka Zothandiza Motani?

Chithandizo chatsopano chosangalatsa kwambiri ndi mankhwala ochepetsa ma virus a sofosbuvir, omwe awonetsedwa kuti samangothandiza kwambiri, komanso ali ndi kuthekera kofupikitsa kwambiri njira zochiritsira kuchokera ku mitundu yayitali kwambiri isanayambike.

Sofosbuvir imagwira ntchito poletsa mavitamini a RNA polymerase. Imeneyi ndi njira yomwe kachilomboka kamatha kupanga okha. M'mayesero azachipatala mankhwalawa, kuphatikiza, adawonetsedwa kuti ndi othandiza kwambiri kupewetsa kachilomboka mwachangu komanso molimba, kulola kufupikitsa kwakukulu kwa mankhwala. Ngakhale mankhwala ena adalowetsa enzyme iyi, kapangidwe ka mankhwalawa ndikuti amasintha mwachangu komanso moyenera kukhala mawonekedwe ake mthupi, kulola kuletsa kwa enzyme. Sofosbuvir anali

Komanso, nthawi zina, kuphatikiza mankhwala osachotsa ma interferon owopsa chifukwa cha mawonekedwe ake osakopa-atha kugwiritsidwanso ntchito. [Ngakhale imagwira ntchito, interferon imadziwika kuti imayambitsa kukhumudwa komanso ngati chimfine. Sofosbuvir ndiye mankhwala oyamba ovomerezedwa ndi a FDA kuti agwiritsidwe ntchito popanda kuthandizira kwa interferon nthawi zina.]

Kodi Mankhwala Atsopano Awa Akufanizirana Bwanji Ndi Mankhwala Ochiritsika?

Ubwino wake, monga ndanenera pamwambapa, ndikuti mitundu yatsopano ndi yayifupi, yolekerera komanso yothandiza. Chosavuta ndichakuti mankhwala atsopano amawononga ndalama zambiri. Komabe, ngati wina ayang'ana zonse zomwe zikuchitika, zomwe zimaphatikizapo ndalama zopangira mankhwala osokoneza bongo, chifukwa chokhoza kupewa zovuta zowopsa kwambiri zotenga matenda a hepatitis C, mankhwala atsopanowa ndiwowonjezera bwino pazida.

Kodi Odwala Amayenera Kupanga Zisankho Zawo Motani?

Ndikulangiza kuti odwala apange zisankho zamankhwala mothandizana ndi adotolo atakambirana za momwe matenda awo aliri, momwe chiwindi chawo chilili, komanso kuthekera kwawo kutsatira mankhwala.