Baricitinib: ndi chiani, momwe mungatengere ndi zoyipa zake

Zamkati

• Ndi chiyani
• Kodi baricitinib ikulimbikitsidwa kuchiza COVID-19?
• Momwe mungatenge
• Zotsatira zoyipa
• Yemwe sayenera kugwiritsa ntchito

Baricitinib ndi mankhwala omwe amachepetsa kuyankha kwa chitetezo cha mthupi, amachepetsa magwiridwe antchito a michere omwe amalimbikitsa kutupa komanso kuwonekera kwa ziwalo pangozi ya nyamakazi. Mwanjira iyi, chida ichi chimatha kuchepetsa kutupa, kuthetsa zizindikilo za matendawa monga kupweteka ndi kutupa kwamafundo.

Mankhwalawa amavomerezedwa ndi Anvisa kuti agwiritsidwe ntchito nyamakazi ya nyamakazi, ndi dzina loti Olumiant ndipo itha kugulidwa kuma pharmacies kokha ndi mankhwala, mwa mapiritsi a 2 kapena 4 mg.

Ndi chiyani

Baricitinib akuwonetsedwa kuti amachepetsa kupweteka, kuuma ndi kutupa kwa nyamakazi, kuphatikiza pakuchepetsa kukula kwa mafupa ndi ziwalo.

Mankhwalawa atha kugwiritsidwa ntchito payokha kapena kuphatikiza ndi methotrexate, pochiza nyamakazi.

Kodi baricitinib ikulimbikitsidwa kuchiza COVID-19?

Baricitinib imangovomerezedwa ku United States kuti ichiritse kachilombo koyambitsa matendawa kapena kutsimikiziridwa ndi kuyesa kwa labotale, ikagwiritsidwa ntchito limodzi ndi remdesivir, yomwe ndi ma virus. Remdesivir imavomerezedwa ndi Anvisa pamaphunziro oyesera a Covid-19.

Kafukufuku wina wasonyeza kuti mankhwalawa amatha kuthandiza kuletsa ma coronavirus kulowa m'maselo ndikuchepetsa nthawi yakufa komanso kufa kwakanthawi kochepa, kwa achikulire omwe ali mchipatala ndi ana azaka zopitilira ziwiri omwe amafunikira mpweya, makina opumira mpweya kapena oxygenation ndi nembanemba ya kunja. Onani mankhwala onse ovomerezeka ndi owerengera a Covid-19.

Malinga ndi Anvisa, kugula kwa baricitinib ku pharmacy ndikololedwa, koma kwa anthu okhawo omwe ali ndi mankhwala azachipatala a nyamakazi.

Momwe mungatenge

Baricitinib ayenera kumwedwa pakamwa malinga ndi upangiri wa zamankhwala, kamodzi patsiku, musanadye kapena mutadya.

Phaleli liyenera kutengedwa nthawi yofananira, koma mukaiwala, mlingowu uyenera kutengedwa mukangokumbukira ndikusintha magawo malinga ndi izi, ndikupitiliza kulandira chithandizo molingana ndi nthawi zomwe zakonzedwa. Osachulukitsa mlingowo kuti mupange mlingo woiwalika.

Asanayambe mankhwala ndi baricitinib, adotolo akuyenera kukulimbikitsani kuti mukayezetse kuti muwone ngati mulibe chifuwa chachikulu kapena matenda ena.

Zotsatira zoyipa

Zina mwazovuta zomwe zimachitika mukamamwa mankhwala a baricitinib ndizomwe zimapangitsa kuti mapiritsi azigwiritsidwa ntchito, nseru kapena chiopsezo chowonjezeka cha matenda omwe amaphatikizapo chifuwa chachikulu, fungal, bakiteriya kapena ma virus monga herpes simplex kapena herpes zoster.

Kuphatikiza apo, baricitinib itha kuwonjezera chiopsezo chokhala ndi lymphoma, mitsempha yayikulu yam'mimba kapena embolism ya m'mapapo.

Ndibwino kuti musiye kugwiritsa ntchito ndikufunafuna chithandizo chamankhwala mwachangu ngati ziwopsezo zowopsa za baricitinib zikuwoneka, monga kupuma movutikira, kumangika pakhosi, kutupa mkamwa, lilime kapena nkhope, kapena ming'oma, kapena ngati mutenga baricitinib mu Mlingo waukulu kuposa womwe umalimbikitsidwa pakutsata zizindikiritso za zovuta zoyipa.

Yemwe sayenera kugwiritsa ntchito

Baricitinib sayenera kugwiritsidwa ntchito ndi amayi apakati kapena oyamwitsa, ngati ali ndi chifuwa chachikulu kapena matenda a fungal monga candidiasis kapena pneumocystosis.

Mankhwalawa ayenera kugwiritsidwa ntchito mosamala kwa anthu omwe ali ndi mavuto okutira magazi, kuphatikiza okalamba, onenepa kwambiri, anthu omwe ali ndi mbiri ya thrombosis kapena embolism kapena anthu omwe ati achite opaleshoni ina ndipo amafunika kulephera. Kuphatikiza apo, kusamala kuyeneranso kugwiritsidwa ntchito kwa anthu omwe ali ndi vuto la chiwindi kapena impso, kuchepa magazi kapena anthu omwe ali ndi chitetezo chamthupi chofooka, omwe angafunikire kusintha kwa mankhwala.