Khansa Yapamwamba Ya M'mawere Asanapite Patsogolo Komanso Akamaliza Kusamba

Zamkati

• 1.Kodi njira yoyamba yothandizira khansa ya m'mawere yomwe imalandira khansa ya m'mawere ndi iti?
• 2. Kodi khansa ya m'mawere imathandizidwa bwanji mwa amayi omwe asanabadwe?
• 3. Kodi ndi chithandizo chanji chomwe chaperekedwa kwa amayi omwe atha msambo?
• 4. Kodi chemotherapy kapena chithandizo chamankhwala chimagwiritsidwa ntchito liti pochiza khansa ya m'mawere?

Chidule

Khansa ya m'mawere yamatenda (yomwe imadziwikanso kuti khansa ya m'mawere) amatanthauza kuti khansara yafalikira kuchokera pachifuwa kupita kumalo ena mthupi. Amadziwikabe kuti khansa ya m'mawere chifukwa ma metastases ali ndi mtundu womwewo wamaselo a khansa.

Njira zamankhwala zimadalira mawonekedwe apadera a chotupacho, monga ngati ali ndi cholandilira cha hormone komanso ngati ali ndi HER2-positive. Zina mwazinthu zimaphatikizapo thanzi lamakono, chithandizo chilichonse chomwe mudalandira kale, komanso kuti khansa idatenga nthawi yayitali bwanji kuti ibwererenso.

Chithandizo chimadaliranso momwe khansa iliri komanso momwe mwadutsamo. Nawa mafunso omwe mungafunse dokotala wanu za khansa ya m'mawere yapamtima yokhudzana ndi kusamba.

1.Kodi njira yoyamba yothandizira khansa ya m'mawere yomwe imalandira khansa ya m'mawere ndi iti?

Thandizo la mahormonal, kapena endocrine therapy, nthawi zambiri limakhala gawo loyambirira la chithandizo cha azimayi omwe ali ndi khansa ya m'mawere yolandila mahomoni. Nthawi zina amatchedwa anti-hormone treatment chifukwa imakhala ngati yotsutsana ndi mankhwala obwezeretsa mahomoni (HRT).

Cholinga ndikuchepetsa mayendedwe a estrogen ndi progesterone mthupi kuti atseke mahomoniwa kuti asafike ku maselo a khansa ndikupeza estrogen yomwe akufunikira kuti ikule.

Thandizo la mahormoni lingagwiritsidwe ntchito kusokoneza chidwi cha mahomoni pakukula kwa maselo ndikugwira ntchito kwathunthu. Ngati mahomoni atsekedwa kapena kuchotsedwa, ma cell a khansa sangakhale ndi moyo.

Thandizo la mahomoni limayimitsanso maselo am'mabere athanzi kuti asalandire mahomoni omwe amatha kupangitsa kuti maselo a khansa abwererenso mkati mwa bere kapena kwina kulikonse.

2. Kodi khansa ya m'mawere imathandizidwa bwanji mwa amayi omwe asanabadwe?

Chithandizo cha khansa ya m'mawere mwa azimayi omwe ali ndi khansa yamankhwala am'mimba amayamba kuponderezedwa ndi ovari. Njirayi imachepetsa mahomoni m'thupi kuti muchepetse chotupa cha estrogen chomwe chimayenera kukula.

Kupondereza kwamchiberekero kumatheka mwa njira ziwiri izi:

• Mankhwala osokoneza bongo amatha kuletsa thumba losunga mazira kupanga estrogen, yomwe imapangitsa kusamba kwakanthawi.
• Kuchita opaleshoni yotchedwa oophorectomy kumatha kuchotsa mazira m'mimba ndikuimitsa kupanga kwa estrogen kosatha.

Aromatase inhibitor itha kuperekedwa kwa azimayi omwe ali ndi vuto loyambitsa matendawa potengera kupondereza kwa ovari. Aromatase inhibitors atha kukhala:

• anastrozole (Arimidex)
• exemestane (Aromasin)
• letrozole (Femara)

Tamoxifen, antiestrogen, imagwiritsidwanso ntchito pochiza khansa ya m'mawere m'mayi azimayi omwe ali ndi vuto la premenopausal. Imatha kuletsa khansara kubwerera kapena kufalikira kwina.

Tamoxifen sangakhale yotheka ngati khansara ipita patsogolo pa chithandizo cham'mbuyomu cha tamoxifen. Kuphatikiza kuponderezedwa kwa ovari ndi tamoxifen kwapezeka kuti kumathandizira kupulumuka poyerekeza ndi tamoxifen yokha.

3. Kodi ndi chithandizo chanji chomwe chaperekedwa kwa amayi omwe atha msambo?

Kupondereza kwamchiberekero sikofunikira kwa amayi omwe atha msinkhu. Mimba yawo yambiri yasiya kale kupanga kuchuluka kwa estrogen. Amangopanga zochepa m'matupi awo amafuta ndi adrenal gland.

Mankhwala a Postmenopausal hormone nthawi zambiri amakhala ndi aromatase inhibitor. Mankhwalawa amachepetsa kuchuluka kwa estrogen m'thupi poletsa minofu ndi ziwalo kupatula thumba losunga mazira kupanga estrogen.

Zotsatira zoyipa za aromatase inhibitors ndi monga:

• kutentha
• nseru
• kusanza
• mafupa kapena mafupa opweteka

Zotsatira zoyipa zazikulu zimaphatikizapo kupatulira mafupa komanso kuchuluka kwa cholesterol.

Amayi a Postmenopausal amatha kupatsidwa tamoxifen kwa zaka zingapo, nthawi zisanu kapena kupitilira apo. Ngati mankhwalawa agwiritsidwa ntchito kwa zaka zosakwana zisanu, aromatase inhibitor nthawi zambiri amatha kupatsidwa zaka zotsalazo.

Mankhwala ena omwe angaperekedwe ndi CDK4 / 6 inhibitors kapena fulvestrant.

4. Kodi chemotherapy kapena chithandizo chamankhwala chimagwiritsidwa ntchito liti pochiza khansa ya m'mawere?

Chemotherapy ndiyo njira yayikulu yothandizira khansa yamawere yamagazi (ma receptor receptor-negative ndi HER2-negative). Chemotherapy itha kugwiritsidwanso ntchito limodzi ndi njira zochiritsira za HER2 za khansa ya m'mawere ya HER2.

Chemotherapy itha kugwiritsidwa ntchito pamavuto akulu a khansa yolandila mahomoni, khansa ya HER2-negative.

Ngati mankhwala oyamba a chemotherapy, kapena kuphatikiza mankhwala, atasiya kugwira ntchito ndipo khansa imafalikira, mankhwala achiwiri kapena achitatu atha kugwiritsidwa ntchito.

Kupeza chithandizo choyenera kumatha kuyesedwa. Zomwe zili zoyenera kwa wina sizingakhale zoyenera kwa inu. Tsatirani dongosolo lanu la mankhwala ndikulankhulana ndi dokotala wanu. Adziwitseni ngati china chake chikuchitika kapena sichikugwira ntchito.

Mutha kukhala ndi masiku ovuta m'tsogolomu, koma zimathandiza kudziwa njira zonse zamankhwala zomwe mungasankhe.