Chiyeso cha Chibadwa cha BRAF
Zamkati
- Kodi mayeso amtundu wa BRAF ndi chiyani?
- Amagwiritsidwa ntchito yanji?
- Chifukwa chiyani ndikufunika mayeso amtundu wa BRAF?
- Kodi chimachitika ndi chiyani pakuyesedwa kwa majini a BRAF?
- Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?
- Kodi pali zoopsa zilizonse pamayeso?
- Kodi zotsatirazi zikutanthauza chiyani?
- Kodi pali china chilichonse chomwe ndiyenera kudziwa pamayeso a BRAF?
- Zolemba
Kodi mayeso amtundu wa BRAF ndi chiyani?
Kuyesedwa kwa majeremusi a BRAF kumayang'ana kusintha, kotchedwa kusintha, mu jini yotchedwa BRAF. Chibadwa ndiye gawo lobadwa kuchokera kwa amayi ndi abambo ako.
Gulu la BRAF limapanga mapuloteni omwe amathandiza kuchepetsa kukula kwa maselo. Amadziwika kuti oncogene. Oncogene imagwira ntchito ngati chopangira mafuta pagalimoto. Nthawi zambiri, oncogene amasintha kukula kwama cell pakufunika. Koma ngati muli ndi kusintha kwa BRAF, zili ngati kuti gasi wakhazikika, ndipo jini silingaletse maselo kukula. Kukula kosalamulirika kwama cell kumatha kubweretsa khansa.
Kusintha kwa BRAF kumatha kubadwa kuchokera kwa makolo anu kapena kudzapezedwa mutakula. Kusintha komwe kumachitika mtsogolo m'moyo nthawi zambiri kumachitika chifukwa cha chilengedwe kapena chifukwa chakulakwitsa komwe kumachitika mthupi lanu panthawi yamagawi. Kusintha kwa cholowa cha BRAF ndikosowa kwambiri, koma kumatha kuyambitsa mavuto akulu azaumoyo.
Zosintha (zomwe zimadziwikanso kuti somatic) kusintha kwa BRAF kumakhala kofala kwambiri. Kusintha kumeneku kwapezeka pafupifupi theka la matenda onse a khansa ya pakhungu. Kusintha kwa BRAF kumapezekanso pamavuto ena ndi mitundu ingapo ya khansa, kuphatikiza khansa ya m'matumbo, chithokomiro, ndi mazira. Khansa yokhala ndi kusintha kwa BRAF imakonda kukhala yayikulu kuposa omwe sanasinthe.
Mayina ena: Kusanthula kwa majini a BRAF, Melanoma, BRAF V600 mutation, cobas
Amagwiritsidwa ntchito yanji?
Mayesowa amagwiritsidwa ntchito nthawi zambiri kufunafuna kusintha kwa BRAF kwa odwala khansa ya khansa kapena khansa ina yokhudzana ndi BRAF. Mankhwala ena a khansa amathandiza makamaka kwa anthu omwe ali ndi kusintha kwa BRAF. Mankhwala omwewo sagwira ntchito ndipo nthawi zina amakhala owopsa kwa anthu omwe alibe kusintha.
Kuyesedwa kwa BRAF kungathenso kugwiritsidwa ntchito kuti muwone ngati muli pachiwopsezo cha khansa kutengera mbiri ya banja lanu kapena / kapena mbiri yaumoyo wanu.
Chifukwa chiyani ndikufunika mayeso amtundu wa BRAF?
Mungafunike kuyesedwa kwa BRAF ngati mwapezeka kuti muli ndi khansa ya khansa kapena mtundu wina wa khansa. Kudziwa ngati mukusintha kungathandize omwe akukuthandizani kuti apereke chithandizo choyenera.
Mwinanso mungafunike mayesowa kuti muwone ngati muli pachiwopsezo chachikulu chotenga khansa. Zowopsa zimaphatikizira mbiri ya khansa komanso / kapena kukhala ndi khansa adakali aang'ono. Zaka zimadalira mtundu wa khansa.
Kodi chimachitika ndi chiyani pakuyesedwa kwa majini a BRAF?
Mayeso ambiri a BRAF amachitika motsatira njira yotchedwa chotupa chotupa. Pakati pa biopsy, wothandizira zaumoyo amatenga kachidutswa kakang'ono podula kapena kupukuta pamwamba pa chotupa. Ngati wothandizira wanu akuyenera kuyesa zotupa mkati mwa thupi lanu, atha kugwiritsa ntchito singano yapadera kuti atulutse nyembazo.
Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?
Nthawi zambiri simusowa zokonzekera zapadera za mayeso a BRAF.
Kodi pali zoopsa zilizonse pamayeso?
Mutha kukhala ndi mikwingwirima kapena kutuluka magazi pamalo omwe mumapezeka biopsy. Muthanso kukhala ndi vuto pang'ono patsambalo kwa tsiku limodzi kapena awiri.
Kodi zotsatirazi zikutanthauza chiyani?
Ngati muli ndi khansa ya khansa kapena mtundu wina wa khansa, ndipo zotsatira zikuwonetsa kuti muli ndi kusintha kwa BRAF, omwe amakupatsirani akhoza kukupatsani mankhwala omwe apangidwa kuti akwaniritse kusinthaku. Mankhwalawa amatha kugwira ntchito kuposa mankhwala ena.
Ngati muli ndi khansa ya khansa kapena mtundu wina wa khansa, ndipo zotsatira zikuwonetsani osatero mutasintha, omwe akukuthandizani adzakupatsani mitundu yosiyanasiyana ya mankhwala ochizira khansa yanu.
Ngati simunapezeke ndi khansa ndipo zotsatira zanu zikuwonetsa kuti muli ndi kusintha kwa majini a BRAF, ndizo satero zikutanthauza kuti muli ndi khansa, koma muli ndi chiopsezo chachikulu cha khansa. Koma kuwunika khansa pafupipafupi, monga kuyesa khungu, kumatha kuchepetsa ngozi. Mukamayesa khungu, wothandizira zaumoyo amayang'anitsitsa khungu lanu mthupi lonse kuti awone ngati pali timadontho tambiri komanso zophulika zina zokayikitsa.
Lankhulani ndi omwe amakupatsani zomwe mungachite kuti muchepetse chiopsezo chanu.
Dziwani zambiri zamayeso a labotale, magawo owerengera, ndi zotsatira zakumvetsetsa.
Kodi pali china chilichonse chomwe ndiyenera kudziwa pamayeso a BRAF?
Mutha kumva omwe amakupatsani mwayi akunena za kusintha kwa V600E. Pali mitundu yosiyanasiyana ya kusintha kwa BRAF. V600E ndiye mtundu wofala kwambiri wa kusintha kwa BRAF.
Zolemba
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- American Cancer Society [Intaneti]. Atlanta: Bungwe la American Cancer Society Inc .; c2018. Oncogenes ndi majini opondereza chotupa; [yasinthidwa 2014 Jun 25; yatchulidwa 2018 Jul 10]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://www.cancer.org/cancer/cancer-causes/genetics/genes-and-cancer/oncogenes-tumor-suppressor-genes.html
- American Cancer Society [Intaneti]. Atlanta: Bungwe la American Cancer Society Inc .; c2018. Chithandizo Choyang'aniridwa ndi Khansa ya Khungu la Melanoma; [yasinthidwa 2018 Jun 28; yatchulidwa 2018 Jul 10]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.cancer.org/cancer/melanoma-skin-cancer/treating/targeted-therapy.html
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Zomwe zili patsamba lino siziyenera kugwiritsidwa ntchito m'malo mwa chithandizo chamankhwala kapena upangiri. Lumikizanani ndi othandizira azaumoyo ngati muli ndi mafunso okhudzana ndi thanzi lanu.