Kodi mayeso a Calcitonin ndi ati ndipo amachitika bwanji

Zamkati

• Ndi chiyani
• Momwe mayeso amachitikira
• Momwe mungayesere zotsatira zamayeso

Calcitonin ndi mahomoni opangidwa ndi chithokomiro, omwe ntchito yake ndikuwongolera kuchuluka kwa calcium yomwe imazungulira m'magazi, kudzera pazotsatira monga kupewa kuyambiranso kashiamu m'mafupa, kuchepetsa kuyamwa kwa calcium m'matumbo ndikuwonjezera kutuluka kwa impso.

Chizindikiro chachikulu cha mayeso a calcitonin ndikutulukira kwa khansa ya chithokomiro yotchedwa medullary thyroid carcinoma, yomwe imadziwika kuti ndi chotupa cha matendawa, chifukwa imayambitsa kukwera kwa mahomoni. Kuyesa kupezeka kwa chithokomiro C-cell hyperplasia ndichizindikiro china chofala, ngakhale hormone iyi imathanso kukwezedwa munthawi zina, monga khansa ya m'mapapo kapena m'mawere.

Monga mankhwala, kugwiritsa ntchito calcitonin kumatha kuwonetsedwa pochiza matenda monga kufooka kwa mafupa, calcium yochulukirapo m'magazi, matenda a Paget kapena Reflex systematic dystrophy. Ngati mukufuna kudziwa zambiri za calcitonin, onani zomwe calcitonin ndi zomwe amachita.

Ndi chiyani

Mayeso a calcitonin atha kuyitanidwa kuti:

• Kuunikira kukhalapo kwa medullary chithokomiro carcinoma;
• Kufufuza kwa hyperplasia yama cell C, omwe ndi maselo amtundu wa chithokomiro omwe amatulutsa calcitonin;
• Kuwunika kwa achibale a odwala omwe ali ndi medullary chithokomiro carcinoma, kuti adziwe chotupacho;
• Kuwona kuyankha kwachithandizo cha medullary chithokomiro carcinoma;
• Kutsatira khansa pambuyo pochotsa chithokomiro, monga zikuyembekezeredwa kuti mikhalidweyo imakhala yotsika ngati ingachiritsidwe.

Ngakhale izi ndizizindikiro zazikulu, ziyenera kukumbukiridwa kuti calcitonin imathanso kuwonjezeka munthawi zina, monga mitundu ina ya khansa, monga khansa ya m'magazi, mapapo, kapamba, khansa ya m'mawere kapena prostate, pamaso pa matenda a impso, matenda a bakiteriya, hypergastrinemia, kapena chifukwa cha hyperparathyroidism hypercalcemia kapena zinthu zina.

Momwe mayeso amachitikira

Mlingo wa Calcitonin umachitika mu labotale, popempha dokotala, pomwe magazi amatengedwa kuti apeze magawo oyambira.

Makhalidwe a Calcitonin amakhudzidwa ndimikhalidwe ingapo, yomwe imaphatikizapo kugwiritsa ntchito mankhwala ena, monga Omeprazole kapena corticosteroids, zaka, kutenga pakati, kusuta fodya komanso kumwa mowa, kotero njira yodziwitsira kuti mayesowo akhale odalirika ndikuchita limodzi ndi adotolo kuyezetsa calcium kapena pentagastrin kulowetsedwa, kupatula zowonjezera zotsekemera za calcitonin.

Chiyeso cha calcitonin chosakaniza ndi calcium kulowetsedwa ndichomwe chimapezeka, ndipo chimachitika m'mawa, pamimba yopanda kanthu. Kalasiamu imayikidwa kudzera mumitsempha, pa 0, 2, 5 ndi 10 mphindi mutalowetsedwa, kuti muwone ngati chiwonjezerekocho chimawoneka chachilendo kapena ayi.

Momwe mungayesere zotsatira zamayeso

Makhalidwe abwinobwino a calcitonin amasiyana malinga ndi labotale yomwe imayesa. Makhalidwe abwinobwino ndi omwe amakhala pansipa 8.4 pg / ml mwa amuna ndi 5 pg / ml mwa akazi. Pambuyo pa kukondoweza kwa calcium, omwe ali pansi pa 30 pg / ml komanso abwino ataposa 100 pg / ml atha kuonedwa ngati abwinobwino. Pakati pa 30 ndi 99 pg / dl, kuyezetsa kumawerengedwa kuti sikokwanira, ndipo kuyesedwa kwina kuyenera kuchitidwa kuti mutsimikizire matendawa.