Mitengo Yopulumuka ndi Chiwonetsero cha Matenda a m'magazi a Lymphocytic

Zamkati

• Kupulumuka kwamatenda a khansa ya m'magazi
• Zinthu zomwe zimakhudza malingaliro a khansa ya m'magazi ya lymphocytic
• Kodi tatsala pang'ono kuchiritsidwa?
• Kulimbana ndi chithandizo cha matenda a m'magazi a lymphocytic
• Nenani zakukhosi kwanu
• Dziphunzitseni nokha
• Khalani achangu
• Chotsani matenda anu

Matenda a m'magazi a lymphocytic

Matenda a lymphocytic leukemia (CLL) ndi mtundu wa khansa yomwe imakhudza magazi ndi mafupa. Mafupa ndi chinthu chofewa, chofewa mkati mwa mafupa omwe amatulutsa maselo amwazi. CLL ndi zotsatira za kusintha kosiyanasiyana kwa majini mu DNA yamaselo omwe amatulutsa magazi. Zomwe zimayambitsa kusintha kumeneku sizikudziwika. Kusintha uku kwa DNA kumachitika pakadutsa nthawi yamoyo, m'malo mongokhala ngati kusintha kwina kwamtundu komwe kumachitika asanabadwe.

Ngati muli ndi CLL, mafupa anu amapanga ma lymphocyte ambiri - mtundu wa khungu loyera la magazi. Ma lymphocyte awa sagwira ntchito moyenera. Amayambitsa mavuto ena chifukwa chotsatira njira zina zamagazi zomwe zimapangidwa.

Zizindikiro za CLL zimatha kusiyanasiyana kutengera gawo kapena kukula kwa matendawa. Simungakhale ndi zizindikilo koyambirira. Matendawa akamakula, zizindikiro zimaphatikizapo:

• ma lymph node owonjezera
• kutopa
• malungo
• thukuta usiku
• kuonda
• matenda pafupipafupi
• kukhuta m'mimba

Konzani nthawi yanu ndi dokotala ngati mungapeze zina mwazizindikiro pamwambapa. Mukazindikira kuti mukudwala matendawa, malingaliro anu amakhala abwino.

Kupulumuka kwamatenda a khansa ya m'magazi

CLL ili ndi chiopsezo chachikulu kuposa khansa zina zambiri. Zaka zisanu zapulumuka pafupifupi 83%. Izi zikutanthauza kuti anthu 83 pa anthu 100 alionse omwe ali ndi vutoli ali moyo zaka zisanu atawapeza. Komabe, kwa iwo azaka zopitilira 75, kupulumuka kwa zaka zisanu kutsikira kutsika mpaka 70%. Pamene ofufuza akupitiliza kuphunzira zambiri za CLL, zimawonekeratu momwe zimakhalira zovuta kulosera zotsatira. Pali zifukwa zambiri zofunika kuziganizira pa chithandizo ndi kupulumuka. Zotsatira za anthu omwe ali ndi CLL ndizovuta chifukwa chakusapezeka kapena kupezeka kwa ma cell osiyanasiyana, monga IGHV, CD38, ndi ZAP70, komanso kusintha kwa majini.

Malinga ndi National Cancer Institute, mu 2017 padzakhala milandu 20,100 yatsopano ya CLL ku United States. Ndipo matendawa adzapha anthu pafupifupi 4,660 mu 2017.

Anthu ena ali pachiwopsezo chachikulu chotenga CLL. Matendawa amapezeka kwambiri mwa abambo kuposa akazi, ndipo amatha kukhudza omwe ali ndi zaka zopitilira 60. M'malo mwake, pafupifupi 80% ya omwe atangopezeka ndi CLL ali ndi zaka zopitilira 60. Anthu aku Caucasus nawonso atha kutenga khansa yamtunduwu.

Kuphatikiza pa mtundu komanso jenda, mbiri yabanja ya CLL kapena zovuta zina zamagazi zimakulitsanso chiopsezo chanu. Kuwonetsedwa kwa mankhwala ena monga mankhwala ophera tizilombo ndi tizilombo toyambitsa matenda kumawonjezeranso ngozi.

Zinthu zomwe zimakhudza malingaliro a khansa ya m'magazi ya lymphocytic

Kwachidziwikire, matenda a khansa ya m'magazi amatha kupulumuka kwambiri, koma zinthu zingapo zimakhudza momwe mumaonera. Izi zimaphatikizaponso gawo la matendawa ndi momwe mumayankhira kuchipatala, komanso ma cell ndi ma genetic.

Pambuyo pozindikira, gawo lotsatira ndikutulutsa matendawa. Pakadali pano pali magawo awiri a CLL: Rai ndi Binet.

Rai imapezeka kwambiri ku United States, pomwe Binet imagwiritsidwa ntchito kwambiri ku Europe. Gawo la Rai limatanthauzira magawo 5 kuyambira 0 mpaka 4. Gawo 0 limawerengedwa kuti ndi lowopsa, gawo 1-2 limayesedwa ngati chiwopsezo chapakati, ndipo gawo la 3-4 limawoneka kuti ndiwowopsa. Chiwopsezo ndi momwe matendawa amapitilira msanga. Zowopsa kwambiri, CLL ikuyembekezeka kupita patsogolo mwachangu. Dongosolo la Binet limagwiritsa ntchito A, B, ndi C.

Kuyika masitepe kumatsimikizika potengera zinthu zosiyanasiyana monga kuwerengetsa magazi komanso kutenga ma lymph node, chiwindi, ndi ndulu. Njira zolumikizirana pakati panu ndi katswiri wa khansa, kapena oncologist, ndizofunikira. Ndiwothandiza kwambiri kuti mudziwe zambiri zamankhwala ndi chisamaliro chanu. Popeza matendawa ndi ovuta, amathanso kukupatsirani chitsogozo potengera vuto lanu la CLL.

Chithandizo sichingakhale chofunikira nthawi yomweyo ngati zotsatira za mafupa anu a m'mafupa, kuyerekezera kujambula, ndi kuyezetsa magazi kukuwonetsa koyambirira kokhala pachiwopsezo chochepa. Zaka, chiopsezo cha matenda ndi zizindikilo zonse zimathandizira kuthandizira kusankha njira zamankhwala. Chipatala cha Mayo akuti palibe umboni kuti kuchiza msanga CLL kutalikitsa miyoyo. Madokotala ambiri amasiya kulandira chithandizo adakali pano kuti anthu asamve zovuta komanso zovuta zina. Kumayambiriro kwa madokotala a CLL amayang'anira matendawa nthawi zonse, ndipo amayamba kulandira chithandizo pakapita.

Ngati muli ndi gawo lotsogola kwambiri la CLL lomwe lili pachiwopsezo chachikulu, mankhwala osiyanasiyana amatha kusintha kupulumuka kwanu. Mankhwalawa amaphatikizapo kuphatikiza mankhwala a chemotherapy kupha ma cell a khansa. Muthanso kukhala wokonzeka kupatsirana ma cell a mafupa. Pochita izi, mudzalandira maselo athanzi lamagazi athanzi kuchokera kwa woperekayo. Izi zitha kulimbikitsa kupangika kwa maselo amwazi anu athanzi.

Kodi tatsala pang'ono kuchiritsidwa?

Odwala achichepere omwe sanalandire chithandizo m'mbuyomu, omwe ali ndi thanzi labwino, komanso omwe ali ndi zida zina zabwino zamagulu, chemotherapy yophatikiza yotchedwa FCR (fludarabine, cyclophosphamide, rituximab) yawonetsa lonjezo lalikulu. Malinga ndi magazini ya Blood, chithandizo ichi chingapatse moyo kwa nthawi yayitali komanso mwina kuchiritsa anthu ena.

Vuto ndiloti mankhwalawa si a aliyense. Omwe ali ndi zaka zopitilira 65, anthu omwe ali ndi vuto la impso, komanso omwe ali ndi matenda ena sangalole chithandizo ichi. Kwa anthu ena, zitha kuwonjezera chiopsezo chotenga matenda ndi khansa zina.

Kulimbana ndi chithandizo cha matenda a m'magazi a lymphocytic

Kukhala ndi khansa kumabweretsa mitundu yosiyanasiyana yamalingaliro. Masiku ena mumamva bwino, komanso masiku ena, osakhala bwino. Nthawi zina mumatha kukhala ndi nkhawa, kukwiya, mantha, mantha, kapena chiyembekezo. Ngakhale mutakhala pachiwopsezo cha CLL ndipo simulandila chithandizo, mutha kuopa kuti matendawa akupita patsogolo.

Nenani zakukhosi kwanu

Osasunga malingaliro anu mkati. Mutha kusunga malingaliro anu kuti mupewe kukhumudwitsa abale kapena abwenzi. Koma kufotokoza momwe mukumvera ndikofunika kuthana ndi matendawa. Lankhulani ndi wachibale wokhulupirika kapena mnzanu kuti akutsimikizireni ndikuthandizani, ndipo mulole kuti mukhale ndi chisoni. Palibe vuto kulira. Nthawi zambiri, mumakhala bwino mukamasulidwa.

Ngati simukukhulupirira kulankhula ndi ena za matenda anu, lembani zakukhosi kwanu. Funsani dokotala wanu za magulu othandizira khansa. Kapenanso mutha kulankhula ndi mlangizi yemwe amagwira ntchito ndi anthu omwe ali ndi khansa.

Dziphunzitseni nokha

Kuzindikira khansa kumatha kubweretsa nkhawa komanso nkhawa. Koma mukamadziwa zambiri ndikumvetsetsa za vutoli, zidzakhala zosavuta kuvomereza zenizeni zanu zatsopano. American Cancer Society ikukulimbikitsani kuti mukhale oyimira kumbuyo kwanu. Musayembekezere dokotala wanu kuti akuphunzitseni pa CLL.

Fufuzani za vutoli ndikukhala ndi zatsopano zamankhwala aposachedwa kuti mufunse mafunso oganiza bwino. Lembani zolemba zanu panthawi yomwe mumadalira, ndipo funsani dokotala kuti akufotokozereni zomwe simukuzimvetsa. Ndikofunikanso kupeza zodalirika mukafuna intaneti. Funsani dokotala wanu kuti akufotokozereni komwe mungawerenge zambiri za matenda anu.

Khalani achangu

Kuchita masewera olimbitsa thupi ndi njira ina yolimbana ndi matenda a CLL. Kuchita masewera olimbitsa thupi ndikofunikira chifukwa zochitika zimapangitsa ubongo wanu kupanga ma endorphins. Awa ndi mahomoni "akumva bwino". Kuchita masewera olimbitsa thupi kumawongolera malingaliro anu. Ikhozanso kulimbitsa chitetezo cha mthupi lanu ndikukuthandizani kulimbana ndi matenda. Pitani kokayenda kapena kukwera njinga, kapena kupita kukalasi ya yoga kapena kalasi ina yochita masewera olimbitsa thupi.

Chotsani matenda anu

Zingakhale zovuta kuchotsa malingaliro anu pa khansa. Njira imodzi yothanirana ndikupeza zinthu zosangalatsa zomwe zingakuthandizeni kupumula komanso kupumula. Onani zosangalatsa, monga kujambula, zaluso, kuvina, kapena zaluso. Kuti mupumule, ganizirani za kusinkhasinkha kwa zithunzi. Njira imeneyi imakuthandizani kuti muziyang'ana pazithunzi zabwino zokuthandizani kupumula ndikuchepetsa nkhawa. Ndipo mukakhala ndi tsiku labwino, gwiritsani ntchito mphamvu zanu kuti mukhale ndi moyo mokwanira, zomwe zingachotse malingaliro anu pa thanzi lanu.