Cyclosporine, Kapiso Wamlomo

Zamkati

• Mfundo zazikulu za cyclosporine
• Kodi cyclosporine ndi chiyani?
• Chifukwa chimagwiritsidwa ntchito
• Momwe imagwirira ntchito
• Zotsatira zoyipa za cyclosporine
• Zotsatira zofala kwambiri
• Zotsatira zoyipa
• Momwe mungatengere cyclosporine
• Mlingo wa nyamakazi ya nyamakazi
• Mlingo wa psoriasis
• Mlingo wopewa kukanidwa kwa impso, chiwindi, ndi mtima
• Maganizo apadera
• Tengani monga mwalamulidwa
• Machenjezo a Cyclosporine
• Machenjezo a FDA
• Chenjezo la kuwonongeka kwa chiwindi
• Kuchuluka kwa potaziyamu kuchenjeza
• Chenjezo la kuyanjana kwa chakudya
• Machenjezo kwa anthu omwe ali ndi matenda ena
• Machenjezo kwa magulu ena
• Cyclosporine imatha kulumikizana ndi mankhwala ena
• Maantibayotiki
• Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)
• Zosakaniza
• Mankhwala osokoneza bongo a acid
• Mankhwala oletsa kubereka
• Mankhwala osokoneza bongo
• Mankhwala osokoneza bongo a cholesterol
• Mankhwala osokoneza bongo
• Corticosteroid
• Ma anticonvulsants
• Zitsamba
• Gout mankhwala
• Mankhwala a HIV
• Mankhwala ochepetsa madzi
• Mankhwala a khansa
• Mankhwala ena
• Zofunikira pakumwa cyclosporine
• Zonse
• Yosungirako
• Zowonjezeranso
• Kuyenda
• Kudziyang'anira pawokha
• Kuwunika kuchipatala
• Kupezeka
• Chilolezo chisanachitike
• Kodi pali njira zina?

Mfundo zazikulu za cyclosporine

1. Cyclosporine oral capsule imapezeka ngati mankhwala achibadwa komanso ngati mankhwala osokoneza bongo. Mayina a Brand: Gengraf, Neoral, Sandimmune. Chonde dziwani kuti Neoral ndi Gengraf (cyclosporine modified) sanatengeke mofanana ndi Sandimmune (cyclosporine osasinthidwa), chifukwa chake mankhwalawa sangathe kugwiritsidwa ntchito mosinthana.
2. Cyclosporine imabwera ngati kapisozi wamlomo, yankho la m'kamwa, madontho amaso, ndi mawonekedwe ojambulidwa.
3. Cyclosporine m'kamwa kapisozi amagwiritsidwa ntchito pochizira kutupa kwa nyamakazi ndi psoriasis. Amagwiritsidwanso ntchito popewera kukana kuyika kwa chiwalo.

Kodi cyclosporine ndi chiyani?

Cyclosporine ndi mankhwala akuchipatala. Zimabwera ngati kapisozi wamlomo, yankho la m'kamwa, ndi madontho amaso. Imabweranso m'njira yojambulidwa, yomwe imangoperekedwa ndi othandizira azaumoyo.

Cyclosporine oral capsule imapezeka ngati dzina lodziwika bwino la mankhwala Gengraf, Zosowa, ndi Sandimmune. Ikupezekanso ngati mankhwala achibadwa.

Mankhwala achibadwa nthawi zambiri amakhala otsika poyerekeza ndi mtundu wamaina. Nthawi zina, sangapezeke mwamphamvu zonse kapena mitundu yonse monga dzina lodziwika bwino la mankhwalawa.

Chonde dziwani kuti Neoral ndi Gengraf sizingagwiritsidwe ntchito mosinthana ndi Sandimmune.

Chifukwa chimagwiritsidwa ntchito

Cyclosporine imagwiritsidwa ntchito popewa kukana chiwalo choikidwa. Amagwiritsidwanso ntchito kuchepetsa kutupa kwa nyamakazi ya nyamakazi (RA) komanso psoriasis yoopsa.

Mtundu wa dzina lake wotchedwa Sandimmune umangogwiritsidwa ntchito popewa kukana chiwalo choikidwa.

Momwe imagwirira ntchito

Cyclosporine ndi gulu la mankhwala otchedwa immunosuppressants. Gulu la mankhwala ndi gulu la mankhwala omwe amagwiranso ntchito chimodzimodzi. Mankhwalawa amagwiritsidwa ntchito pochiza zofananira.

Cyclosporine imagwira ntchito pochepetsa chitetezo chamthupi. Maselo oyera a magazi, gawo limodzi la chitetezo chanu cha mthupi, nthawi zambiri amalimbana ndi zinthu m'thupi lanu zomwe sizikhala mwachilengedwe, monga chiwalo choikidwa. Cyclosporine imayimitsa maselo oyera am'magazi kuti asawononge chiwalo china.

Pankhani ya RA kapena psoriasis, cyclosporine imayimitsa chitetezo chanu chamthupi kuti chisasokoneze matupi anu.

Zotsatira zoyipa za cyclosporine

Cyclosporine imatha kuyambitsa zovuta zochepa kapena zoyipa. Mndandanda wotsatira uli ndi zovuta zina zomwe zingachitike mukamamwa cyclosporine.

Mndandandawu sungaphatikizepo zovuta zonse zomwe zingachitike. Kuti mumve zambiri pazomwe zingachitike chifukwa cha cyclosporine, kapena maupangiri amomwe mungathanirane ndi zovuta zina, lankhulani ndi dokotala kapena wamankhwala.

Cyclosporine oral capsule sichimayambitsa kugona.

Zotsatira zofala kwambiri

Zotsatira zoyipa zomwe zimachitika ndi cyclosporine ndi monga:

• kuthamanga kwa magazi
• magulu otsika a magnesium mthupi lanu
• magazi aundana mu impso zanu
• kupweteka m'mimba
• kukula kwa tsitsi m'malo ena
• ziphuphu
• kunjenjemera
• mutu
• kukula kukula kwa m'kamwa mwanu

Ngati zotsatirazi ndizochepa, zimatha kutha masiku angapo kapena milungu ingapo. Ngati ali ovuta kwambiri kapena osapita, lankhulani ndi dokotala kapena wamankhwala.

Zotsatira zoyipa

Itanani dokotala wanu nthawi yomweyo ngati muli ndi zovuta zina. Itanani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukukumana ndi zachipatala. Zotsatira zoyipa komanso zizindikilo zake zimatha kukhala izi:

Kuwonongeka kwa chiwindi. Zizindikiro zimaphatikizapo:

• magazi mkodzo
• mkodzo wakuda
• mipando yotumbululuka
• chikasu cha khungu lako kapena kuyera kwa maso ako
• ululu m'mimba mwanu chapamwamba

Kuwonongeka kwa impso. Zizindikiro zimaphatikizapo:

• magazi mkodzo

Mavuto amtima. Zizindikiro zimaphatikizapo:

• kutupa kwa mapazi anu kapena miyendo yakumunsi

Mavuto am'mapapo. Zizindikiro zimaphatikizapo:

• kuvuta kupuma

Momwe mungatengere cyclosporine

Mlingo wa cyclosporine omwe dokotala amakupatsani umadalira pazinthu zingapo. Izi zikuphatikiza:

• mtundu ndi kuuma kwa chikhalidwe chomwe mukugwiritsa ntchito cyclosporine kuchiza
• zaka zanu
• mawonekedwe a cyclosporine omwe mumatenga
• matenda ena omwe mungakhale nawo

Nthawi zambiri, dokotala wanu amakupangitsani muyeso wochepa ndikusintha pakapita nthawi kuti mufike pamlingo woyenera kwa inu. Potsirizira pake adzapereka mankhwala ochepetsetsa omwe amapereka zomwe mukufuna.

Chidziwitso chotsatirachi chimalongosola miyezo yomwe amagwiritsidwa ntchito kwambiri kapena amalimbikitsidwa. Komabe, onetsetsani kuti mwatenga mlingo womwe dokotala akukulemberani. Dokotala wanu adzazindikira mlingo woyenera kuti ugwirizane ndi zosowa zanu.

Mlingo ndi mafomu onse omwe sangakhale nawo sangaphatikizidwe pano.

Mlingo wa nyamakazi ya nyamakazi

Zowonjezera: Cyclosporine

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: Mamiligalamu 25 (mg), 50 mg, ndi 100 mg

Mtundu: Gengraf

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mtundu: Zosowa

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mlingo wachikulire (wazaka 18 kapena kupitirira)

Mlingo umatengera kulemera.

• Mlingo woyambira: Ma milligram 2.5 pa kilogalamu (mg / kg) patsiku, ogawa magawo awiri (1.25 mg / kg pa mlingo).
• Zolemba malire mlingo: 4 mg / kg pa tsiku.
• Zindikirani: Ngati mulibe zotsatira zabwino pambuyo pa chithandizo chamasabata a 16, dokotala wanu akuyimitsani kusiya kumwa cyclosporine.

Mlingo wa ana (zaka 0-17 zaka)

Mlingo sunakhazikitsidwe kwa anthu ochepera zaka 17.

Mlingo wa psoriasis

Zowonjezera: Cyclosporine

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg, 50 mg, ndi 100 mg

Mtundu: Gengraf

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mtundu: Zosowa

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mlingo wachikulire (wazaka 18 kapena kupitirira)

Mlingo umatengera kulemera.

• Mlingo woyambira: 2.5 mg / kg pa tsiku, ogawa magawo awiri (1.25 mg / kg pa mlingo).
• Zolemba malire mlingo: 4 mg / kg pa tsiku.
• Zindikirani: Ngati mulibe zotsatira zabwino pambuyo pa masabata a 6 pamlingo wololera kwambiri, dokotala wanu akuyimitsani kumwa cyclosporine.

Mlingo wa ana (zaka 0-17 zaka)

Mlingo sunakhazikitsidwe kwa anthu ochepera zaka 17.

Mlingo wopewa kukanidwa kwa impso, chiwindi, ndi mtima

Zowonjezera: Cyclosporine

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg, 50 mg, ndi 100 mg

Mtundu: Gengraf

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mtundu: Zosowa

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mtundu: Sandimmune

• Mawonekedwe: kapisozi wamlomo
• Mphamvu: 25 mg ndi 100 mg

Mlingo wachikulire (wazaka 18 kapena kupitirira)

Mlingo wa cyclosporine umatha kusiyanasiyana, kutengera kulemera kwa thupi lanu, chiwalo chomwe chadulidwa, ndi mankhwala ena omwe mukumwa.

• Neoral, Gengraf, ndi generic: Mlingo umasiyana. Mlingo wamba wamasiku onse ndi ma 7-9 milligrams pa kilogalamu (mg / kg) ya kulemera kwa thupi komwe kumatengedwa muyezo umodzi wofanana ngakhale tsiku lonse.
• Sandimmune ndi generic:
  • Tengani mlingo wanu woyamba kutatsala maola 4 mpaka 12 musanabadwe. Mlingowu umakhala wa 15 mg / kg. Dokotala wanu akhoza kukupatsani mlingo wa 10-14 mg / kg pa tsiku.
  • Pitirizani kumwa mlingo womwewo mutapatsidwa opaleshoni ya masabata 1-2. Pambuyo pake, muchepetse ndi 5% sabata kuti musamalire 5-10 mg / kg pa tsiku.

Mlingo wa ana (zaka 1-17 zaka)

Mlingo wa cyclosporine umasiyana kutengera kulemera kwa thupi la mwana wanu, chiwalo chomwe waikidwa, ndi mankhwala ena omwe mwana wanu amamwa.

• Neoral, Gengraf, ndi generic: Mlingo umasiyana. Mlingo woyambirira wamasiku onse ndi 7-9 milligram pa kilogalamu (mg / kg) ya kulemera kwa thupi yogawika magawo awiri ofanana tsiku lililonse.
• Sandimmune ndi generic:
  • Tengani mlingo wanu woyamba kutatsala maola 4 mpaka 12 musanabadwe. Mlingowu umakhala wa 15 mg / kg. Dokotala wanu akhoza kukupatsani mlingo wa 10-14 mg / kg pa tsiku.
  • Pitirizani kumwa mlingo womwewo mutapatsidwa opaleshoni ya masabata 1-2. Pambuyo pake, muchepetse ndi 5% sabata kuti musamalire 5-10 mg / kg pa tsiku.

Mlingo wa ana (miyezi 0-11 miyezi)

Mlingo sunakhazikitsidwe kwa ana ochepera miyezi 12.

Maganizo apadera

• Kwa anthu omwe ali ndi vuto la impso: Cyclosporine imatha kuyambitsa matenda a impso. Ngati muli ndi vuto la impso, dokotala wanu akhoza kukupatsani kuchepa kwa cyclosporine.
• Kwa anthu omwe ali ndi vuto la chiwindi: Cyclosporine imatha kuyambitsa matenda a chiwindi. Ngati muli ndi vuto la chiwindi, dokotala wanu akhoza kukupatsani kuchepa kwa cyclosporine.

Tengani monga mwalamulidwa

Cyclosporine imagwiritsidwa ntchito pochiza kwa nthawi yayitali. Zimabwera ndi zoopsa zazikulu ngati simukuzitenga monga mwalamulo.

Mukasiya kumwa mankhwalawa kapena osamwa konse: Thupi lanu limakana chiwalo chanu choikidwa kapena zizindikiro zanu za RA kapena psoriasis zitha kubwerera.

Ngati mwaphonya Mlingo kapena osazitenga nthawi yake: Thupi lanu limakana kukayika kwanu, kumayambitsa mavuto akulu azaumoyo. Kapena zizindikiro zanu za RA kapena psoriasis zitha kubwerera.

Ngati mutenga zochuluka kwambiri: Mutha kukhala ndimankhwala owopsa mthupi lanu. Zizindikiro za bongo za mankhwalawa zingaphatikizepo:

• chikasu cha khungu lako kapena kuyera kwa maso ako
• kutupa kwa mikono yanu, manja, mapazi, akakolo, kapena miyendo yakumunsi

Ngati mukuganiza kuti mwamwa kwambiri mankhwalawa, itanani dokotala wanu kapena funsani malangizo kuchokera ku American Association of Poison Control Center ku 800-222-1222 kapena kudzera pa chida chawo pa intaneti. Koma ngati matenda anu akukulira, itanani 911 kapena pitani kuchipatala chapafupi pomwepo.

Zomwe muyenera kuchita mukaphonya mlingo: Ngati mwaphonya mlingo, tengani msanga momwe mungathere. Komabe, ngati kwangotsala maola ochepa kuti muyambe kumwa mankhwala, tsatirani mlingo womwe mwaphonyawo.

Musayese kugwira mwakumwa miyezo iwiri nthawi imodzi. Izi zitha kubweretsa zovuta zoyipa.

Momwe mungadziwire ngati mankhwalawa akugwira ntchito: Mutha kudziwa kuti mankhwalawa akugwira ntchito ngati:

• thupi lanu samakana chiwalo choikidwa kapena minofu
• muli ndi zizindikiro zochepa za RA
• muli ndi ma psoriasis ochepa

Machenjezo a Cyclosporine

Mankhwalawa amabwera ndi machenjezo osiyanasiyana.

Machenjezo a FDA

• Mankhwalawa ali ndi machenjezo a bokosi lakuda. Chenjezo la bokosi lakuda ndi chenjezo loopsa kwambiri kuchokera ku Food and Drug Administration (FDA). Chenjezo la bokosi lakuda limachenjeza madokotala ndi odwala za zovuta zamankhwala zomwe zitha kukhala zowopsa.
• Chenjezo la matenda. Cyclosporine imatha kukulitsa chiopsezo cha matenda opatsirana. Zingakulitsenso chiopsezo chanu chotupa chotupa kapena khansa yapakhungu.
• Chenjezo la matenda akhungu. Ngati muli ndi psoriasis ndipo mwalandira psoralen kuphatikiza ma ultraviolet A therapy, methotrexate, tar tar, therapy radiation, kapena ultraviolet light therapy, mutha kukhala ndi mwayi wambiri wodwala matenda akhungu mukamamwa makapisozi a cyclosporine.
• Kuthamanga kwa magazi ndi matenda a impso. Mankhwalawa amatha kuyambitsa kuthamanga kwa magazi komanso matenda a impso.
• Chenjezo la adotolo. Othandizira azaumoyo okha omwe ali ndi vuto la kasamalidwe ka chitetezo chamthupi cha matendawa ndi omwe ayenera kupatsidwa cyclosporine. "Systemic immunosuppressive therapy" ndi chithandizo cha matenda amthupi (momwe chitetezo chamthupi cha munthu chimagwirira thupi lawo).
• Chenjezo lachilengedwe. Kuyamwa kwa makapisozi a Sandimmune (cyclosporine osasinthidwa) ndi yankho pakamwa pakagwiritsidwe ntchito kwanthawi yayitali kumatha kukhala kosayembekezereka. Ndikulimbikitsidwa kuti anthu omwe amamwa makapisozi a Sandimmune kapena yankho pakamwa kwakanthawi amayang'aniridwa ndi cyclosporine yamagazi kuti apewe poizoni komanso kukanidwa kwa ziwalo.
• Chenjezo la Gengraf ndi Neoral. Gengraf ndi Neoral (cyclosporine modified) amalowetsedwa kwambiri ndi thupi poyerekeza ndi makapisozi a Sandimmune ndi yankho la m'kamwa. Chifukwa chake mankhwalawa sangathe kugwiritsidwa ntchito mosinthana popanda kuyang'aniridwa ndi wothandizira zaumoyo.

Chenjezo la kuwonongeka kwa chiwindi

Kutenga cyclosporine kumatha kuyambitsa kuwonongeka kwa chiwindi komanso kulephera kwa chiwindi, makamaka mukamwa kwambiri. Mwinanso akhoza kupha.

Kuchuluka kwa potaziyamu kuchenjeza

Kumwa mankhwalawa kumakweza potaziyamu wanu.

Chenjezo la kuyanjana kwa chakudya

Pewani kudya zipatso zamtengo wapatali kapena kumwa madzi amphesa mukamamwa mankhwalawa. Kugwiritsa ntchito zipatso zamphesa kumatha kuwonjezera kuchuluka kwa cyclosporine mthupi lanu.

Machenjezo kwa anthu omwe ali ndi matenda ena

Kwa anthu omwe ali ndi vuto la impso ndi chiwindi: Cyclosporine imatha kuyambitsa matenda a impso ndi chiwindi. Ngati muli ndi vuto la impso kapena chiwindi, kuchuluka kwa cyclosporine kumatha kukulitsa.

Kwa anthu omwe ali ndi matenda akulu: Cyclosporine imatha kukulitsa chiopsezo cha matenda opatsirana kwambiri a virus, monga matenda a polyomavirus. Izi zitha kukhala zowopsa kwambiri, ngakhale kupha.

Machenjezo kwa magulu ena

Kwa amayi apakati: Cyclosporine ndi gulu C la mankhwala osokoneza bongo. Izi zikutanthauza zinthu ziwiri:

1. Kafukufuku wazinyama awonetsa zovuta kwa mwana wosabadwa mayi atamwa mankhwalawo.
2. Sipanakhale maphunziro okwanira omwe adachitika mwa anthu kuti atsimikizire momwe mankhwalawo angakhudzire mwana wosabadwayo.

Lankhulani ndi dokotala ngati muli ndi pakati kapena mukufuna kutenga pakati. Cyclosporine iyenera kugwiritsidwa ntchito panthawi yapakati pokhapokha phindu lomwe lingakhalepo likutsimikizira kuwopsa kwa mwana wosabadwayo.

Kwa amayi omwe akuyamwitsa: Cyclosporine imadutsa mkaka wa m'mawere ndipo imatha kubweretsa zovuta zoyipa. Uzani dokotala wanu ngati mukuyamwitsa. Inu ndi dokotala muyenera kusankha ngati mungayamwitse kapena kumwa cyclosporine.

Makapisozi a Sandimmune omwe ali ndi dzina amakhala ndi mowa (mowa). Ethanol ndi zinthu zina zomwe zili mu mankhwalawa zimatha kudutsa mkaka wa m'mawere ndipo zimabweretsa zovuta kwa mwana yemwe akuyamwitsa.

Kwa okalamba: Ngati muli ndi zaka 65 kapena kupitilira apo, mumakhala ndi vuto la kuthamanga kwa magazi mukamagwiritsa ntchito cyclosporine. Mukamakalamba, ziwalo zanu, monga chiwindi ndi impso, sizigwira ntchito monga kale. Pofuna kupewa kuwonongeka kwa impso, dokotala wanu akhoza kukuyambitsani pamlingo wochepa.

Kwa ana:

• Ndani adasamutsidwa impso, chiwindi, kapena mtima: Ana azaka zapakati pa miyezi 6 kapena kupitilira apo omwe adalandira ziwalo zina ndikuchiritsidwa ndi cyclosporine sanakhale ndi zovuta zina.
• Ndani ali ndi nyamakazi kapena psoriasis: Mankhwalawa sanakhazikitsidwe ngati otetezeka kapena othandiza kuti agwiritsidwe ntchito kwa anthu ochepera zaka 18 omwe ali ndi nyamakazi kapena psoriasis.

Cyclosporine imatha kulumikizana ndi mankhwala ena

Cyclosporine imatha kulumikizana ndi mankhwala ena angapo. Kuyanjana kosiyanasiyana kumatha kubweretsa zovuta zosiyanasiyana. Mwachitsanzo, ena amatha kusokoneza momwe mankhwala amagwirira ntchito, pomwe ena amatha kuyambitsa zovuta zina.

M'munsimu muli mndandanda wa mankhwala omwe angagwirizane ndi cyclosporine. Mndandandawu mulibe mankhwala onse omwe angagwirizane ndi cyclosporine.

Musanagwiritse ntchito cyclosporine, onetsetsani kuti mukuwuza dokotala komanso wamankhwala zamankhwala onse, pa-counter, ndi mankhwala ena omwe mumamwa. Auzeni za mavitamini, zitsamba, ndi zowonjezera zilizonse zomwe mumagwiritsa ntchito. Kugawana izi kungakuthandizeni kupewa kuyanjana komwe kungachitike.

Ngati muli ndi mafunso okhudzana ndi mankhwala omwe angakukhudzeni, funsani dokotala kapena wamankhwala.

Maantibayotiki

Kutenga cyclosporine ndi maantibayotiki ena kumatha kubweretsa chiopsezo chowonjezeka cha kuwonongeka kwa impso. Zitsanzo za mankhwalawa ndi monga:

• ciprofloxacin
• alireza
• magwire
• trimethoprim / sulfamethoxazole
• alireza

Maantibayotiki otsatirawa atha kubweretsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuwonjezera chiopsezo chanu chazovuta. Zitsanzo za mankhwalawa ndi monga:

• azithromycin
• chithuchithu
• erythromycin
• quinupristin / dalfopristin

Maantibayotiki otsatirawa amachepetsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kupangitsa kuti cyclosporine isagwire ntchito moyenera. Pamene cyclosporine imagwiritsidwa ntchito pokana kukana kwa ziwalo, izi zimatha kubweretsa kukanidwa kwa chiwalo choikidwa. Mankhwalawa ndi awa:

• nafcillin
• rifampin

Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)

Kutenga cyclosporine ndi mankhwalawa kumatha kukulitsa chiopsezo cha impso. Zitsanzo za mankhwalawa ndi monga:

• ibuprofen
• sulindac
• naproxen
• diclofenac

Zosakaniza

Kutenga cyclosporine ndi mankhwala ena ophera fungal kumatha kubweretsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuyambitsa zovuta zina kapena kukulitsa chiopsezo cha impso. Zitsanzo za mankhwalawa ndi monga:

• amphotericin B
• ketoconazole
• fluconazole
• chithu
• alireza

Terbinafine, mankhwala ena antifungal, amachepetsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kupangitsa kuti cyclosporine isagwire ntchito moyenera. Pamene cyclosporine imagwiritsidwa ntchito popewera kukanidwa, izi zimatha kubweretsa kukana chiwalo choikidwa.

Mankhwala osokoneza bongo a acid

Kutenga cyclosporine ndi mankhwalawa kumatha kukulitsa chiopsezo cha impso. Zitsanzo za mankhwalawa ndi monga:

• anayankha
• cimetidine

Mankhwala oletsa kubereka

Kutenga cyclosporine ndi mankhwala omwe amagwiritsidwa ntchito poletsa kubereka kumatha kuwonjezera kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuyambitsa zovuta zina.

Mankhwala osokoneza bongo

Kutenga tacrolimus ndi cyclosporine imatha kuwonjezera chiopsezo cha impso.

Mankhwala osokoneza bongo a cholesterol

Kutenga cyclosporine ndi mankhwala otsatirawa a cholesterol kungapangitse ngozi yanu kuwonongeka kwa impso:

• fenofibrate
• alireza

Mukamwa cyclosporine ndi mankhwala ena a cholesterol, kuchuluka kwa mankhwalawa kumatha kuchuluka. Izi zitha kuyambitsa zovuta zina monga kupweteka kwa minofu ndi kufooka. Mankhwalawa ndi awa:

• alirezatalischi
• alirezatalischi
• alireza
• alireza
• fluvastatin

Mankhwala osokoneza bongo

Kumwa mankhwalawa ndi cyclosporine kumatha kukulitsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuyambitsa zovuta zina. Zitsanzo za mankhwalawa ndi monga:

• alireza
• alireza
• alireza

Corticosteroid

Kutenga methylprednisolone ndi cyclosporine imatha kuwonjezera kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuyambitsa zovuta zina.

Ma anticonvulsants

Kumwa mankhwalawa ndi cyclosporine kumachepetsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kupangitsa kuti cyclosporine isagwire ntchito moyenera. Pamene cyclosporine imagwiritsidwa ntchito pokana kukana kwa ziwalo, izi zimatha kubweretsa kukanidwa kwa chiwalo choikidwa. Zitsanzo za mankhwalawa ndi monga:

• carbamazepine
• kutchfuneralhome
• anayankha
• muthoni

Zitsamba

Kutenga Wort wa St. ndi cyclosporine ingachepetse kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kupangitsa kuti cyclosporine isagwire ntchito moyenera. Pamene cyclosporine ikugwiritsidwa ntchito pokana kukana kwa ziwalo, izi zimatha kubweretsa kukanidwa kwa chiwalo choikidwa.

Gout mankhwala

Kutenga alirakhalid ndi cyclosporine imatha kukulitsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuwonjezera chiopsezo chanu chazovuta.

Kutenga colchicine ndi cyclosporine akhoza azitaya kuwonongeka impso.

Mankhwala a HIV

Ngati mukumwa mankhwala otchedwa protease inhibitors kuti muthane ndi kachilombo ka HIV, pitani kuchipatala musanamwe cyclosporine. Dokotala wanu angafunikire kuchepetsa kuchuluka kwa cyclosporine kuti muchepetse zovuta zomwe zingayambike chifukwa chomwa mankhwalawa ndi cyclosporine. Zitsanzo za mankhwalawa ndi monga:

• kutchfuneralhome
• alireza
• mwambo
• alireza

Mankhwala ochepetsa madzi

Musatenge cyclosporine ndi mankhwalawa. Itha kuwonjezera potaziyamu mthupi lanu ndipo imatha kuyambitsa mavuto. Zotsatirazi zimatha kuphatikizira kugunda kwa mtima, kutopa, kufooka kwa minofu, ndi nseru. Zitsanzo za mankhwalawa ndi monga:

• alireza
• amiloride

Mankhwala a khansa

Kutenga cyclosporine ndi mankhwala ena omwe amagwiritsidwa ntchito pochiza khansa kumatha kukulitsa kuchuluka kwa mankhwala m'thupi lanu. Izi zitha kuwonjezera chiopsezo chanu chazovuta. Zitsanzo za mankhwalawa ndi monga:

• alireza
• kutuloji
• etoposide
• kutchfuneralhome

Kutenga nyimbo, Mankhwala ena a khansa, omwe ali ndi cyclosporine akhoza kuwonjezera ngozi yanu ya kuwonongeka kwa impso.

Mankhwala ena

Kutenga cyclosporine ndi mankhwala aliwonse omwe ali pansipa kungayambitse kuchuluka kwa mankhwala m'thupi lanu. Izi zitha kuwonjezera chiopsezo chanu chazovuta. Zitsanzo za mankhwalawa ndi monga:

• alireza
• aliskiren
• chithu
• alireza
• Chinthaka
• chibadul
• repanlinide
• sirolimus

Mankhwala ena amatha kuwonjezera kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kuyambitsa zovuta zina. Zitsanzo za mankhwalawa ndi monga:

• kutchfun
• bromocriptine
• danazol
• imatinib
• metoclopramide
• nefazodone

Mankhwala ena amachepetsa kuchuluka kwa cyclosporine mthupi lanu. Izi zitha kupangitsa kuti cyclosporine isagwire ntchito moyenera. Pamene cyclosporine imagwiritsidwa ntchito pokana kukana kwa ziwalo, izi zimatha kubweretsa kukanidwa kwa chiwalo choikidwa. Zitsanzo za mankhwalawa ndi monga:

• chithu
• ootetsa
• mndandanda
• alireza
• ticlopidine

Zofunikira pakumwa cyclosporine

Kumbukirani izi ngati dokotala wanu akukulemberani cyclosporine.

Zonse

• Tengani cyclosporine nthawi yomweyo tsiku lililonse.
• Osaphwanya, kutafuna, kapena kudula makapisozi a cyclosporine.
• Dziwani kuti mutha kumva fungo mukatsegula chidebecho koyamba. Izi zidzatha pakapita nthawi.

Yosungirako

• Sungani kutentha kwapakati pakati pa 68 ° F mpaka 77 ° F (20 ° C ndi 25 ° C).
• Sungani mankhwalawa kutali ndi kutentha komanso kutentha.
• Musasunge mankhwalawa m'malo onyowa kapena onyowa, monga mabafa.

Zowonjezeranso

Mankhwala a mankhwalawa amakonzanso. Simuyenera kusowa mankhwala atsopano kuti mankhwalawa adzazidwenso. Dokotala wanu adzalemba kuchuluka kwa mafuta obwezerezedwanso pamankhwala anu.

Kuyenda

Mukamayenda ndi mankhwala anu:

• Nthawi zonse muzinyamula mankhwala anu. Mukamauluka, musayikenso m'thumba lofufuzidwa. Sungani m'thumba lanu.
• Osadandaula za makina a X-ray pabwalo la ndege. Sangathe kuvulaza mankhwala anu.
• Mungafunike kuwonetsa ogwira ntchito ku eyapoti chizindikiro cha mankhwala anu. Nthawi zonse muzinyamula chidebe choyambirira cholembedwa ndi mankhwala.
• Musayike mankhwalawa m'galimoto yamagolovu amgalimoto yanu kapena siyani m'galimoto. Onetsetsani kuti musachite izi nyengo ikatentha kapena kuzizira kwambiri.
• Lankhulani ndi wamankhwala anu musanapite kukaonetsetsa kuti muli ndi mankhwalawa okwanira. Kutengera komwe mukupita, mutha kukhala ndi vuto kupeza mankhwalawa.

Kudziyang'anira pawokha

Ngati mukumwa generic cyclosporine kapena dzina la mankhwala ena kupatula Sandimmune, pewani kuwala kwambiri kwa dzuwa kapena malo okuchenjera.

Kuwunika kuchipatala

Dokotala wanu amatha kukuyang'anirani ndi mayeso ena amwazi musanamwe komanso mukamalandira chithandizo cha cyclosporine. Izi ndizowonetsetsa kuti ndizabwino kuti mutenge. Mayeso atha kuchitidwa kuti muwone zinthu monga zanu:

• magulu a cyclosporine
• chiwindi chimagwira
• ntchito ya impso
• mafuta m'thupi
• mulingo wa magnesium
• mulingo wa potaziyamu

Kupezeka

Osati mankhwala aliwonse omwe amakhala ndi mankhwalawa. Mukadzaza mankhwala anu, onetsetsani kuti mwayitanitsa patsogolo kuti mutsimikizire kuti mankhwala omwe muli nawo ali nawo.

Chilolezo chisanachitike

Makampani ambiri a inshuwaransi amafuna chilolezo choyambirira cha mankhwalawa. Izi zikutanthauza kuti dokotala wanu adzafunika kuvomerezedwa ndi kampani yanu ya inshuwaransi kampani yanu ya inshuwaransi isanakulipireni mankhwalawo.

Kodi pali njira zina?

Palinso mankhwala ena omwe amapezeka kuti athetse vuto lanu. Ena akhoza kukuyenererani kuposa ena. Lankhulani ndi dokotala wanu za mankhwala ena omwe angakuthandizeni.

Chodzikanira: Healthaline yayesetsa kwambiri kuti zidziwitso zonse zikhale zolondola, zomveka bwino, komanso zaposachedwa. Komabe, nkhaniyi sikuyenera kugwiritsidwa ntchito m'malo mwa chidziwitso ndi ukadaulo wa akatswiri pazachipatala. Muyenera kufunsa adotolo kapena akatswiri azaumoyo musanamwe mankhwala aliwonse.Zambiri zamankhwala zomwe zili pano zitha kusintha ndipo sizingapangidwe kuti zigwiritse ntchito, mayendedwe, zodzitetezera, machenjezo, kulumikizana ndi mankhwala, kusokonezeka, kapena zovuta zina. Kusapezeka kwa machenjezo kapena zidziwitso za mankhwala omwe apatsidwa sikuwonetsa kuti kuphatikiza mankhwala kapena mankhwalawa ndiwotetezeka, ogwira ntchito, komanso oyenera kwa odwala onse kapena ntchito zina zilizonse.