EGCG (Epigallocatechin Gallate): Ubwino, Mlingo, ndi Chitetezo

Zamkati

• Kodi EGCG ndi chiyani?
• Mwachilengedwe zimapezeka mu zakudya zosiyanasiyana
• Mutha kupereka zabwino zamathanzi
• Antioxidant ndi anti-inflammatory zotsatira
• Thanzi lamtima
• Kuchepetsa thupi
• Thanzi laubongo
• Mlingo ndi zotsatira zoyipa zomwe zingachitike
• Zotsatira zoyipa
• Mfundo yofunika

Epigallocatechin gallate (EGCG) ndi chomera chapadera chomwe chimapereka chidwi chochuluka pazomwe zingakhudze thanzi.

Amaganiziridwa kuti amachepetsa kutupa, kuthandizira kuchepa thupi, ndikuthandizira kupewa matenda amtima ndi ubongo.

Nkhaniyi ikuwunikanso EGCG, kuphatikiza maubwino ake azaumoyo komanso zoyipa zomwe zingachitike.

Kodi EGCG ndi chiyani?

Amadziwika kuti epigallocatechin gallate, EGCG ndi mtundu wa kapangidwe kazomera kotchedwa catechin. Makatekini amatha kugawidwa m'magulu akulu azomera zotchedwa polyphenols ().

EGCG ndi makatekini ena okhudzana ndi mankhwalawa amakhala ngati ma antioxidants omwe amateteza ku kuwonongeka kwa ma cell chifukwa cha ma radicals aulere ().

Zoyeserera zaulere ndi tinthu tating'onoting'ono tomwe timapangidwa mthupi lanu zomwe zitha kuwononga maselo anu kuchuluka kwawo kukakhala kochuluka kwambiri. Kudya zakudya zokhala ndi ma antioxidants monga makatekini kumatha kuchepetsa kuwonongeka kwakukulu kwaulere.

Kuphatikiza apo, kafukufuku akuwonetsa kuti makatekini monga EGCG amatha kuchepetsa kutupa ndikupewa matenda ena, kuphatikiza matenda amtima, matenda ashuga, ndi khansa zina (,).

EGCG imakhalapo mwachilengedwe muzakudya zingapo zopangidwa kuchokera kuzomera koma imapezekanso ngati chowonjezera pazakudya chomwe chimagulitsidwa ngati chotulutsa.

EGCG ndi mtundu wa chomera chotchedwa catechin. Kafukufuku akuwonetsa kuti makatekini monga EGCG atha kutengapo gawo poteteza maselo anu kuti asawonongeke komanso kupewa matenda.

Mwachilengedwe zimapezeka mu zakudya zosiyanasiyana

EGCG mwina imadziwika bwino chifukwa cha udindo wawo monga chida chachikulu chogwiritsira ntchito tiyi wobiriwira.

M'malo mwake, maubwino ambiri azaumoyo omwe amabwera chifukwa chomwa tiyi wobiriwira amadziwika kuti ndi EGCG ().

Ngakhale EGCG imapezeka kwambiri mu tiyi wobiriwira, imapezekanso pang'ono muzakudya zina, monga (3):

• Tiyi: zobiriwira, zoyera, oolong, ndi tiyi wakuda
• Zipatso: cranberries, strawberries, mabulosi akuda, kiwis, yamatcheri, mapeyala, mapichesi, maapulo, ndi mapeyala
• Mtedza: pecans, pistachios, ndi mtedza

Ngakhale EGCG ndi katekin wofufuzidwa kwambiri komanso wamphamvu, mitundu ina monga epicatechin, epigallocatechin, ndi epicatechin 3-gallate itha kuperekanso chimodzimodzi. Kuphatikiza apo, ambiri aiwo amapezeka pamagawo azakudya (3,).

Vinyo wofiira, chokoleti chakuda, nyemba, ndi zipatso zambiri ndi zitsanzo zochepa za zakudya zomwe zimapereka katekisimu wolimbikitsa thanzi ().

EGCG imapezeka kwambiri mu tiyi wobiriwira komanso imapezekanso mumitundu ingapo ya tiyi, zipatso, ndi mtedza wina. Makatekini ena olimbikitsa thanzi amakhala ochuluka mu vinyo wofiira, chokoleti chakuda, nyemba, ndi zipatso zambiri.

Mutha kupereka zabwino zamathanzi

Thupi loyesera, nyama, ndi kafukufuku wowerengeka wa anthu akuwonetsa kuti EGCG imapereka maubwino ambiri azaumoyo, kuphatikiza kuchepa kwa kutupa, kuchepa thupi, komanso thanzi la mtima ndi ubongo.

Pomaliza, kafukufuku wina amafunika kuti timvetsetse momwe EGCG ingagwiritsidwire ntchito ngati chida choletsera kapena kuchiza matenda, ngakhale zambiri pakadali pano zikulonjeza.

Antioxidant ndi anti-inflammatory zotsatira

Zambiri zomwe EGCG imadzinenera kutchuka zimachokera ku mphamvu yake yamphamvu ya antioxidant komanso kuthekera kochepetsa kupsinjika ndi kutupa.

Zoyeserera zaulere ndi tinthu tating'onoting'ono tomwe timatha kuwononga maselo anu. Kugwiritsa ntchito mopitilira muyeso kumabweretsa kupsinjika kwama oxidative.

Monga antioxidant, EGCG imateteza ma cell anu kuwonongeka komwe kumakhudzana ndi kupsinjika kwa oxidative ndipo imapondereza magwiridwe anthawi yotulutsa mankhwala opangidwa mthupi lanu, monga chotupa necrosis factor-alpha (TNF-alpha) ().

Kupsinjika ndi kutupa kumalumikizidwa ndi matenda osiyanasiyana osiyanasiyana, kuphatikiza khansa, matenda ashuga, ndi matenda amtima.

Chifukwa chake, zotsatira zotsutsana ndi zotupa komanso antioxidant za EGCG zimaganiziridwa kuti ndichimodzi mwazifukwa zazikulu zakulepheretsa kugwiritsa ntchito matendawa).

Thanzi lamtima

Kafukufuku akuwonetsa kuti EGCG mu tiyi wobiriwira imatha kuthandizira thanzi la mtima pochepetsa kuthamanga kwa magazi, cholesterol, komanso kuchuluka kwa zolembera m'mitsempha yamagazi - zonse zomwe zimayambitsa matenda amtima (,).

Pakafukufuku wamasabata asanu ndi atatu mwa anthu 33, kumwa 250 mg ya tiyi wobiriwira wokhala ndi EGCG tsiku lililonse zidapangitsa kutsika kwa 4.5% kwa LDL (koipa) cholesterol ().

Kafukufuku wosiyana mwa anthu a 56 adapeza kuchepa kwakukulu kwa magazi, cholesterol, ndi zotupa mwa iwo omwe amamwa tsiku lililonse 379 mg wa tiyi wobiriwira pamiyezi itatu ().

Ngakhale zotsatirazi ndizolimbikitsa, kafukufuku wina amafunika kuti mumvetsetse momwe EGCG mu tiyi wobiriwira ingachepetse chiwopsezo cha matenda amtima.

Kuchepetsa thupi

EGCG ingalimbikitsenso kutaya thupi, makamaka ikamayikidwa limodzi ndi caffeine yomwe imapezeka mu tiyi wobiriwira.

Ngakhale zambiri zomwe zimachitika chifukwa cha kuchuluka kwa kulemera kwa EGCG ndizosagwirizana, kafukufuku wina wazaka zambiri akuti kudya makapu awiri (14.7 ounces kapena 434 ml) wa tiyi wobiriwira patsiku kumalumikizidwa ndi mafuta ochepa thupi ndi kulemera ().

Kafukufuku wowonjezerapo wa anthu apeza kuti kutenga 100-460 mg ya EGCG limodzi ndi 80-300 mg wa caffeine kwa milungu yosachepera 12 kumalumikizidwa ndi kuchepa kwakanthawi kwamafuta ndi kuchepa kwamafuta amthupi ().

Komabe, kusintha kwa kulemera kapena kapangidwe ka thupi sikuwoneka nthawi zonse pamene EGCG imamwedwa popanda caffeine.

Thanzi laubongo

Kafukufuku woyambirira akuwonetsa kuti EGCG mu tiyi wobiriwira itha kutengapo gawo pakukweza magwiridwe antchito amitsempha ndikupewa kufooka kwa matenda amubongo.

M'maphunziro ena, jakisoni wa EGCG wakulitsa kwambiri kutupa, komanso kuchira ndi kusinthanso kwama cell a neural mu mbewa ndi kuvulala kwa msana (,).

Kuphatikiza apo, kafukufuku wowerengeka mwa anthu adapeza kulumikizana pakati pa kumwa kwambiri tiyi wobiriwira komanso kuchepa kwa chiwopsezo cha kuchepa kwa ubongo, komanso matenda a Alzheimer's and Parkinson. Komabe, zomwe zilipo sizigwirizana ().

Kuphatikiza apo, sizikudziwika ngati EGCG makamaka kapena mwina zida zina zamatiyi obiriwira zimakhala ndi zotsatirazi.

Kafukufuku wowonjezereka amafunikira kuti mumvetsetse bwino ngati EGCG itha kupewa kapena kuchiza matenda opatsirana aubongo mwa anthu.

EGCG mu tiyi wobiriwira atha kupereka zabwino zosiyanasiyana zaumoyo, monga kuchepa kwa kutupa, kuchepa thupi, komanso kupewa matenda amtima ndi ubongo. Komabe, kafukufuku wambiri pazakufunika kwake amafunikira.

Mlingo ndi zotsatira zoyipa zomwe zingachitike

Ngakhale EGCG yakhala ikuwerengedwa kwazaka zambiri, zovuta zake zimakhala zosiyanasiyana.

Akatswiri ena amakhulupirira kuti izi zitha kukhala chifukwa EGCG imanyoza mosavuta mpweya wa oxygen ulipo, ndipo anthu ambiri samayamwa bwino munjira yogaya chakudya ().

Chifukwa cha izi sichimveka bwino, koma chikhoza kukhala chokhudzana ndi kuti EGCG yambiri imadutsa m'mimba mwakachetechete kwambiri ndipo imamaliza kuwonongeka ndi mabakiteriya m'matumbo akulu ().

Izi zapangitsa kuti mapulani amiyeso yovuta akhale ovuta.

Chikho chimodzi (ma ola 8 kapena 250 ml) ya tiyi wobiriwira wobiriwira amakhala pafupifupi 50-100 mg wa EGCG. Mlingo womwe umagwiritsidwa ntchito m'maphunziro asayansi nthawi zambiri umakhala wokwera kwambiri, koma ndalama zenizeni sizimagwirizana (,).

Kudyetsa tsiku ndi tsiku kofanana kapena kupitirira 800 mg ya EGCG patsiku kumawonjezera kuchuluka kwa magazi a ma transaminases, chizindikiritso cha kuwonongeka kwa chiwindi (17).

Gulu limodzi la ofufuza limanena kuti mulingo woyenera wa 338 mg wa EGCG patsiku mukamamwa mawonekedwe owonjezera olimba (18).

Zotsatira zoyipa

Ndikofunika kuzindikira kuti EGCG siyotetezeka 100% kapena yopanda chiopsezo. M'malo mwake, zowonjezera za EGCG zakhala zikuphatikizidwa ndi zovuta zoyipa, monga ():

• chiwindi ndi impso kulephera
• chizungulire
• shuga wotsika magazi
• kuchepa kwa magazi m'thupi

Akatswiri ena amati zovuta izi zitha kukhala zokhudzana ndi kuipitsidwa kwa poizoni kwa zowonjezera osati EGCG yomwe, koma mosasamala kanthu, muyenera kukhala osamala kwambiri ngati mukuganiza zakumwa izi.

Kutenga mankhwala owonjezera a EGCG sikuvomerezeka ngati muli ndi pakati, chifukwa kungasokoneze kagayidwe kake ka folate - vitamini B wofunikira pakukula kwa fetus - kukulitsa chiopsezo cha zopunduka monga spina bifida ().

Sizikudziwika ngati ma EGCG othandizira ndi otetezeka kwa azimayi omwe akuyamwitsa, chifukwa chake ndibwino kuti mupewe mpaka kafukufuku wina atapezeka ().

EGCG itha kusokonezanso kuyamwa kwa mankhwala ena akuchipatala, kuphatikiza mitundu ina ya mafuta ochepetsa mafuta m'thupi komanso ma antipsychotic ().

Kuti muwonetsetse chitetezo, nthawi zonse funsani omwe amakuthandizani asanayambe zakudya zina.

Pakadali pano palibe malingaliro omveka bwino a EGCG, ngakhale 800 mg tsiku lililonse mpaka milungu inayi yakhala ikugwiritsidwa ntchito mosamala m'maphunziro. Zowonjezera za EGCG zalumikizidwa ndi zovuta zoyipa ndipo zimatha kusokoneza kuyamwa kwamankhwala.

Mfundo yofunika

EGCG ndichida champhamvu chomwe chitha kupindulitsa thanzi pochepetsa kutupa, kuthandiza kuwonda, komanso kupewa matenda ena akulu.

Imakhala ndi tiyi wobiriwira kwambiri komanso imapezekanso muzakudya zina zamasamba.

Akatengedwa ngati chowonjezera, EGCG nthawi zina imalumikizidwa ndi zovuta zoyipa. Njira yotetezeka kwambiri ndikufunsana ndi omwe amakuthandizani musanawonjezere EGCG pazomwe mumachita kuti muwonetsetse kuti chowonjezerachi ndichabwino kwa inu.