Spironolactone (Aldactone)

Zamkati

• Ndi chiyani
• Momwe mungatenge
• 1. Ofunika matenda oopsa
• 2. Kulephera Kwa Mtima Kwambiri
• 3. Matenda a chiwindi
• 4. Nephrotic Syndrome
• 5. Edema
• 6. Hypokalemia / hypomagnesaemia
• 7. Chithandizo cha preoperative cha Primary Hyperaldosteronism
• 8. Matenda oopsa
• Njira yogwirira ntchito
• Zotsatira zoyipa
• Zotsutsana

Spironolactone, yomwe imadziwika kuti Aldactone, imagwira ntchito ngati diuretic, ikuthandizira kuthana ndi madzi kudzera mumkodzo, komanso ngati antihypertensive, ndipo itha kugwiritsidwa ntchito pochiza kuthamanga kwa magazi, kutupa komwe kumakhudzana ndi zovuta pakugwira kwa mtima kapena matenda m'chiwindi ndi impso, hypokalemia kapena pochiza hyperaldosteronism, mwachitsanzo.

Nthawi zina, chithandizochi chitha kuperekedwa pochizira ziphuphu komanso kupewa kutayika kwa tsitsi, komabe kugwiritsa ntchito kumeneku si gawo lazizindikiro zazikulu za spironolactone, komanso sanatchulidwe mu phukusi.

Spironolactone itha kugulidwa kuma pharmacies, pamtengo wokwera pafupifupi 14 mpaka 45 reais, kutengera ngati munthu wasankha chizindikirocho kapena generic, chofunikira kuti aperekedwe mankhwala.

Ndi chiyani

Spironolactone imasonyezedwa ndi:

• Ofunika matenda oopsa;
• Edema chifukwa cha mavuto amtima, impso kapena chiwindi;
• Ediopathic edema;
• Chithandizo chothandizira mu matenda oopsa;
• Hypokalemia pamene njira zina zimaonedwa ngati zosayenera kapena zosakwanira;
• Kupewa hypokalemia ndi hypomagnesaemia mwa anthu omwe amatenga okodzetsa;
• Kuzindikira ndikuchiza kwa hyperaldosteronism.

Phunzirani za mitundu ina ya okodzetsa ndikuphunzirani momwe amagwirira ntchito.

Momwe mungatenge

Mlingowo umadalira vuto lomwe angalandire:

1. Ofunika matenda oopsa

Mlingo wachizolowezi ndi 50 mg / tsiku mpaka 100 mg / tsiku, womwe pamavuto olimba kapena owopsa amatha kuwonjezeka pang'onopang'ono, pakadutsa milungu iwiri, mpaka 200 mg / tsiku. Chithandizo chikuyenera kupitilizidwa kwa milungu iwiri osachepera kuti muwonetsetse kuti mukumvera bwino. Mlingowo uyenera kusinthidwa pakufunika kutero.

2. Kulephera Kwa Mtima Kwambiri

Mlingo woyambira tsiku lililonse ndi 100 mg muyezo umodzi kapena wogawanika, womwe umatha kusiyanasiyana pakati pa 25 mg ndi 200 mg tsiku lililonse. Muyeso wokhazikika wokonzekera uyenera kutsimikiziridwa kwa munthu aliyense.

3. Matenda a chiwindi

Ngati potaziyamu potaziyamu potaziyamu ndi yayikulu kuposa 1, mulingo woyenera ndi 100 mg / tsiku. Ngati chiwerengerochi ndi chochepera 1, mlingo woyenera ndi 200 mg / tsiku mpaka 400 mg / tsiku. Muyeso wokhazikika wokonzekera uyenera kutsimikiziridwa kwa munthu aliyense.

4. Nephrotic Syndrome

Mlingo wachizolowezi mwa akulu ndi 100 mg / tsiku mpaka 200 mg / tsiku.

5. Edema

Mlingo wamba ndi 100 mg patsiku kwa akulu komanso pafupifupi 3.3 mg pa kg ya kulemera komwe kumayikidwa pang'ono. Mlingowo uyenera kusinthidwa kutengera kuyankha komanso kulolerana kwa munthu aliyense.

6. Hypokalemia / hypomagnesaemia

Mlingo wa 25 mg / tsiku mpaka 100 mg / tsiku umalimbikitsidwa pochiza hypopotassemia ndi / kapena hypomagnesemia yoyambitsidwa ndi diuretics, pomwe potaziyamu wamlomo ndi / kapena zowonjezera ma magnesium sizokwanira.

7. Chithandizo cha preoperative cha Primary Hyperaldosteronism

Matenda a hyperaldosteronism akakhazikitsidwa bwino ndi mayeso owoneka bwino, spironolactone imatha kuperekedwa muyezo wa 100 mg mpaka 400 mg pokonzekera opaleshoni.

8. Matenda oopsa

Iyenera kugwiritsidwa ntchito ngati chithandizo chothandizira komanso pakakhala katulutsidwe wochulukirapo wa aldosterone, hypokalemia ndi metabolic alkalosis. Mlingo woyambira ndi 100 mg / tsiku, womwe ungathe kuwonjezeka, pakufunika, pakadutsa milungu iwiri, mpaka 400 mg / tsiku.

Njira yogwirira ntchito

Spironolactone ndi wotsutsana ndi aldosterone, makamaka m'malo osinthanitsa ndi aldosterone ndi potaziyamu, yomwe ili m'chifuwa cha impso, zomwe zimapangitsa kuti sodium ndi madzi zichotsedwe komanso kuti potaziyamu asungidwe.

Zotsatira zoyipa

Zina mwa zoyipa za spironolactone zitha kuphatikizira zotupa za m'mawere zotupa, leukopenia, thrombocytopenia, kusokonekera kwa ma elektroni, kusintha kwa libido, chisokonezo, chizungulire, matenda am'mimba ndi nseru, chiwindi chachilendo, matenda a Steve-Johnson, kutaya, hypertrichosis, kuyabwa, ming'oma, kupweteka kwa mwendo, kulephera kwa impso, kupweteka kwa m'mawere, kusamba kwa msambo, gynecomastia ndi malaise.

Zotsutsana

Spironolactone sayenera kugwiritsidwa ntchito ndi anthu omwe ali ndi vuto loganizira kwambiri za fomuyi, anthu omwe ali ndi vuto lalikulu la impso, kuwonongeka kwakukulu kwa ntchito ya impso, anuria, matenda a Addison, hyperkalaemia kapena omwe akugwiritsa ntchito mankhwala otchedwa eplerenone.