Chilichonse Chimene Muyenera Kudziwa Zokhudza ADPKD

Zamkati

• Zizindikiro za ADPKD
• Chithandizo cha ADPKD
• Zotsatira zoyipa za chithandizo cha ADPKD
• Kuunikira kwa ADPKD
• Kuzindikira kwa ADPKD
• Zomwe zimayambitsa ADPKD
• Zovuta
• Kutalika kwa moyo ndi malingaliro

Matenda a impso a Autosomal opatsirana kwambiri (ADPKD) ndi matenda osachiritsika omwe amachititsa kuti ziphuphu zikule mu impso.

National Institute of Diabetes and Digestive and Kidney Diseases akuti imakhudza pafupifupi munthu m'modzi mwa anthu 400 mpaka 1,000.

Werengani kuti mudziwe zambiri za izi:

• zizindikiro
• zimayambitsa
• mankhwala

Zizindikiro za ADPKD

ADPKD imatha kuyambitsa zizindikilo zosiyanasiyana, kuphatikiza:

• mutu
• kupweteka kumbuyo kwako
• kupweteka m'mbali zanu
• magazi mkodzo wanu
• kukula kukula kwa m'mimba
• kudzaza m'mimba mwako

Zizindikiro nthawi zambiri zimakula munthu atakula, azaka zapakati pa 30 ndi 40, ngakhale amathanso kuwonekera atakalamba kwambiri. Nthawi zina, zizindikiro zimawoneka muubwana kapena unyamata.

Zizindikiro za matendawa zimangowonjezereka pakapita nthawi.

Chithandizo cha ADPKD

Palibe mankhwala odziwika a ADPKD. Komabe, mankhwala alipo kuti athandizire kuthana ndi matendawa komanso zovuta zake.

Pofuna kuchepetsa kukula kwa ADPKD, dokotala wanu akhoza kukupatsani tolvaptan (Jynarque).

Ndiwo mankhwala okhawo omwe Food and Drug Administration (FDA) avomereza makamaka kuchiza ADPKD. Mankhwalawa atha kuthandiza kuchepetsa kapena kulepheretsa impso kulephera.

Malingana ndi momwe mukufunira komanso chithandizo cha mankhwala, dokotala wanu akhoza kuwonjezera chimodzi kapena zingapo zotsatirazi pa dongosolo lanu la mankhwala:

• Kusintha kwa moyo kumathandizira kuthamanga kwa magazi ndikulimbikitsa thanzi la impso
• mankhwala othandizira kuchepetsa kuthamanga kwa magazi, kuchepetsa ululu, kapena kuchiza matenda omwe angachitike mu impso, kwamikodzo, kapena madera ena
• Kuchotsa ma cysts omwe akupweteka kwambiri
• kumwa madzi tsiku lonse ndikupewa caffeine kuti ichepetse kukula kwa zotupa (ofufuza akuphunzira momwe hydration imakhudzira ADPKD)
• kudya magawo ang'onoang'ono a mapuloteni apamwamba
• kuchepetsa mchere, kapena sodium, mu zakudya zanu
• kupewa potaziyamu wambiri ndi phosphorous mu zakudya zanu
• kuchepetsa kumwa mowa

Kusamalira ADPKD ndikutsatira ndondomeko yanu ya chithandizo kungakhale kovuta, koma ndikofunikira kuti muchepetse kukula kwa matendawa.

Ngati dokotala wanu akukulemberani tolvaptan (Jynarque), muyenera kuyesedwa pafupipafupi kuti muwone thanzi la chiwindi chanu chifukwa mankhwalawo amatha kuwononga chiwindi.

Dokotala wanu amayang'anitsitsa thanzi la impso zanu kuti awone ngati zinthu zili bwino kapena zikuyenda bwino.

Mukayamba kulephera kwa impso, muyenera kulandira dialysis kapena kumuika impso kuti mulipirire kutayika kwa impso.

Lankhulani ndi dokotala wanu kuti mudziwe zambiri zamankhwala omwe mungasankhe, kuphatikiza phindu, zoopsa, komanso mtengo wamankhwala osiyanasiyana.

Zotsatira zoyipa za chithandizo cha ADPKD

Mankhwala ambiri omwe dokotala angawaganizire kuti athandizire kapena kuwongolera ADPKD amakhala ndi zovuta zina.

Mwachitsanzo, Jynarque imatha kuchititsa ludzu kwambiri, kukodza pafupipafupi, ndipo nthawi zina, kuwonongeka kwakukulu kwa chiwindi. Pakhala pali malipoti okhudzana ndi chiwindi choopsa chomwe chimafuna kumuika chiwindi anthu omwe amatenga Jynarque.

Mankhwala ena omwe amalimbana ndi zizindikiro za ADPKD amathanso kubweretsa mavuto. Kuti mudziwe zambiri pazotsatira zamankhwala osiyanasiyana, lankhulani ndi dokotala wanu.

Ngati mukuganiza kuti mwina mwakhala mukukumana ndi zovuta zamankhwala, dziwitsani dokotala nthawi yomweyo. Angalimbikitse kusintha kwa mapulani anu.

Dokotala wanu amathanso kuyitanitsa mayeso a nthawi zonse mukamalandira mankhwala ena kuti muwone ngati chiwindi chikuwonongeka kapena zovuta zina.

Kuunikira kwa ADPKD

Matenda a impso a Polycystic (PKD) ndimatenda amtundu.

Kuyesa kwa DNA kulipo, ndipo pali mitundu iwiri yoyesera:

• Kuyesa kulumikizana kwa Gene. Kuyesaku kumasanthula zolembera zina mu DNA ya mamembala omwe ali ndi PKD. Amafuna zitsanzo zamagazi kuchokera kwa inu komanso mamembala angapo am'banja omwe akukhudzidwa komanso osakhudzidwa ndi PKD.
  
• Kusanthula kwatsatanetsatane / kusanja kwa DNA. Chiyesochi chimafuna mtundu umodzi wokha kuchokera kwa inu. Imafufuza mwachindunji DNA ya majini a PKD.

Kuzindikira kwa ADPKD

Kuti mupeze ADPKD, dokotala wanu adzakufunsani za:

• zizindikiro zanu
• mbiri yazachipatala
• mbiri yazachipatala yabanja

Amatha kuyitanitsa mayeso a ultrasound kapena mayeso ena kuti awone ngati ali ndi zotupa komanso zina zomwe zingayambitse matenda anu.

Angathenso kuyitanitsa kuyesa kwa majini kuti muphunzire ngati muli ndi kusintha kwa majini komwe kumayambitsa ADPKD. Ngati muli ndi jini lomwe lakhudzidwa komanso muli ndi ana, atha kuwalimbikitsa kuti nawonso ayesedwe.

Zomwe zimayambitsa ADPKD

ADPKD ndi chibadwa chobadwa nacho.

Nthawi zambiri, zimachokera pakusintha kwa jini la PKD1 kapena mtundu wa PKD2.

Kuti apange ADPKD, munthu ayenera kukhala ndi mtundu umodzi wa jini lomwe lakhudzidwa. Nthawi zambiri amatenga jini lomwe lakhudzidwa ndi m'modzi mwa makolo awo, koma nthawi zambiri, kusinthako kumatha kuchitika zokha.

Ngati muli ndi ADPKD ndipo wokondedwa wanu alibe ndipo mwasankha kuyambitsa banja limodzi, ana anu adzakhala ndi mwayi wokhala ndi matendawa 50%.

Zovuta

Matendawo amakhalanso pachiwopsezo chazovuta, monga:

• kuthamanga kwa magazi
• matenda opatsirana mumkodzo
• zotupa pachiwindi kapena kapamba
• ma valve amtima osazolowereka
• aneurysm yaubongo
• impso kulephera

Kutalika kwa moyo ndi malingaliro

Kutalika kwa moyo wanu komanso malingaliro anu ndi ADPKD zimadalira pazinthu zingapo, kuphatikiza:

• kusintha komwe kumayambitsa ADPKD
• zovuta zilizonse zomwe mumakhala nazo
• chithandizo chomwe mumalandira komanso momwe mumatsatirira ndondomeko yanu yamankhwala
• thanzi lanu lonse komanso moyo wanu

Lankhulani ndi dokotala wanu kuti mudziwe zambiri za matenda anu komanso malingaliro anu. ADPKD ikapezeka msanga ndikuwongoleredwa moyenera, anthu amatha kukhala ndi moyo wathanzi.

Mwachitsanzo, anthu ambiri omwe ali ndi ADPKD omwe akugwirabe ntchito akawapeza amatha kupitiliza ntchito zawo.

Kuchita zizolowezi zabwino ndikutsatira dongosolo lomwe dokotala akuvomerezani kungakuthandizeni kupewa zovuta ndikupangitsa impso zanu kukhala zathanzi kwanthawi yayitali.