Kuyesa kwa PTH (parathormone): chomwe chiri ndi zomwe zotsatira zake zikutanthauza

Zamkati

• Momwe mayeso amachitikira
• Zotsatira zingatanthauze chiyani

Kuyezetsa kwa PTH kumafunsidwa kuti muwone momwe matenda amtundu wa parathyroid amagwirira ntchito, omwe ndi tiziwalo tating'onoting'ono tomwe timakhala ndi chithokomiro chomwe chimagwira ntchito yotulutsa parathyroid hormone (PTH). PTH imapangidwa kuti iteteze hypocalcemia, ndiye kuti, kutsika kwa calcium m'magazi, komwe kumatha kubweretsa kukomoka komanso kulephera kwa mtima pamavuto owopsa komanso ngati kulibe chithandizo. Dziwani zambiri za hypocalcemia ndi zomwe zingayambitse.

Kuyesaku sikutanthauza kusala kudya ndipo kumachitika ndi pang'ono magazi. Mlingo wa PTH umafunsidwa makamaka kuti upeze hypo kapena hyperparathyroidism, koma umafunikanso pakutsata kwa odwala omwe ali ndi vuto lopweteka kwambiri, ndipo amafunsidwa limodzi ndi kuchuluka kwa calcium m'magazi. Mwa anthu osasintha chilichonse pakupanga mahomoni, mfundo zabwinobwino m'magazi ayenera pakati pa 12 ndi 65 pg / mL, zingasiyane malinga ndi labotale.

Ngakhale kukonzekera sikofunikira mayeso asanayesedwe, ndikofunikira kudziwitsa adotolo za momwe angagwiritsire ntchito mankhwala aliwonse, makamaka mankhwala opatsirana, monga Propofol, mwachitsanzo, chifukwa amatha kuchepetsa kuchuluka kwa PTH, zomwe zimasokoneza kumasulira kwa zotsatira zake ndi dokotala. Kuphatikiza apo, tikulimbikitsidwa kuti zosonkhanitsazo zizipangidwira labotale yodalirika kapena chipatala ndi akatswiri ophunzitsidwa bwino, popeza hemolysis, yomwe nthawi zambiri imayamba chifukwa cha zolakwika mumsonkhanowu, imatha kusokoneza zotsatira zoyeserera.

Momwe mayeso amachitikira

Kuyesaku sikusowa kukonzekera kulikonse, komabe tikulimbikitsidwa kuti zosonkhetsa m'mawa, chifukwa momwe zimakhalira zimatha kusiyanasiyana tsiku lonse. Magazi omwe asonkhanitsidwawo amatumizidwa ku labotale, komwe amawakonza ndikuwayika muchida chomwe amawunikira. Zotsatira zake zimatulutsidwa pafupifupi maola 24 mutasonkhanitsa.

Mahomoni otchedwa parathyroid amapangidwa chifukwa cha kuchepa kwa calcium m'magazi. Amagwira ntchito pamafupa, impso ndi matumbo kuti athandize kupezeka kwa calcium m'magazi ndikupewa hypocalcemia. Kuphatikiza apo, PTH imathandizira kukulitsa kuyamwa kwa vitamini D kuchokera m'matumbo.

Zochita za PTH zimayendetsedwa ndi mahomoni ena, calcitonin, omwe amayamba kupangidwa kashiamu atakhala okwera kwambiri, motero kumachepetsa kupanga kwa PTH ndikulimbikitsa kutulutsa kashiamu mumkodzo, mwachitsanzo. Mvetsetsani momwe zimachitikira komanso mayeso a calcitonin.

Zotsatira zingatanthauze chiyani

Zotsatira za mayeso zimamasuliridwa ndi dokotala limodzi ndi kuchuluka kwa calcium, popeza kupanga parathormone kumadalira kuchuluka kwa calcium m'magazi.

• Hormone yapamwamba ya parathyroid: Nthawi zambiri zimawonetsa hyperparathyroidism, makamaka ngati calcium calcium yamagazi ndiyokwera. Kuphatikiza pa hyperparathyroidism, PTH itha kukwezedwa pakakhala kulephera kwa impso, kuchepa kwa vitamini D ndi hypercalciuria. Mvetsetsani tanthauzo la hyperparathyroidism komanso momwe mungachitire.
• Mahomoni ochepa a parathyroid: Ndi chisonyezero cha hypoparathyroidism, makamaka ngati kuchuluka kwa calcium m'magazi ndikotsika. PTH yotsika kapena yosaoneka imatha kuwonetsanso matenda amthupi okha, kukula kolakwika kwa gland kapena pambuyo pochita opaleshoni. Onani zomwe hypoparathyroidism ndi momwe mungazindikire.

Kuyezetsa kwa PTH kumafunsidwa ndi dokotala akakayikira za hypo kapena hyperparathyroidism, asanachite kapena atachita opareshoni yokhudza chithokomiro kapena ngati pali zizindikiro za hypo kapena hypercalcemia, monga kutopa ndi kupweteka m'mimba, mwachitsanzo. Pezani zomwe zimayambitsa calcium yochulukirapo m'magazi ndi momwe angachiritsire.