Maunyolo Aulere Waulere

Zamkati

• Kodi kuyesa kwaunyolo kwaulere ndi chiyani?
• Amagwiritsidwa ntchito yanji?
• Chifukwa chiyani ndikufunika kuyesedwa kwaulere kwa unyolo?
• Kodi chimachitika ndi chiyani poyesedwa kwaulere?
• Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?
• Kodi pali zoopsa zilizonse poyesa unyolo waulere?
• Kodi zotsatirazi zikutanthauza chiyani?
• Kodi pali china chilichonse chomwe ndiyenera kudziwa za kuyesedwa kwaulere kwa unyolo?
• Zolemba

Kodi kuyesa kwaunyolo kwaulere ndi chiyani?

Maunyolo owala ndi mapuloteni opangidwa ndi maselo am'magazi, mtundu wamaselo oyera amwazi. Maselo a m'magazi amapanganso ma immunoglobulins (ma antibodies). Ma immunoglobulins amateteza thupi kumatenda ndi matenda. Ma immunoglobulins amapangidwa ngati maunyolo opepuka amalumikizana ndi unyolo wolemera, mtundu wina wa mapuloteni. Pamene maunyolo opepuka amalumikizana ndi maunyolo olemera, amadziwika kuti womangidwa maunyolo owala.

Nthawi zambiri, maselo am'magazi am'magazi amadzipangira maunyolo owerengeka owonjezera omwe samangirizidwa ndi maunyolo olemera. M'malo mwake amatulutsidwa m'magazi. Maunyolo osalumikizidwa amadziwika kuti kwaulere maunyolo owala.

Pali mitundu iwiri ya maunyolo owala: lambda ndi kappa maunyolo owala. Kuyesa kwa unyolo waulere kumayeza kuchuluka kwa maunyolo owala a lambda ndi kappa mumwazi. Ngati kuchuluka kwa maunyolo aulere ndikotsika kapena kutsika kuposa zachilendo, kungatanthauze kuti muli ndi vuto lama cell a plasma. Izi zimaphatikizapo ma myeloma angapo, khansa yamagazi am'magazi, ndi amyloidosis, zomwe zimayambitsa mapuloteni owopsa m'magulu osiyanasiyana.

Mayina ena: kappa / lambda ratio yaulere, kappa / lambda wowerengeka wowala, freelite, kappa ndi lambda wowala maunyolo, maunyolo a immunoglobulin aulere

Amagwiritsidwa ntchito yanji?

Kuyesa kwaunyolo kwaulere kumagwiritsidwa ntchito kuthandizira kuzindikira kapena kuwunika zovuta zamaselo a plasma.

Chifukwa chiyani ndikufunika kuyesedwa kwaulere kwa unyolo?

Mungafunike mayesowa ngati muli ndi zizindikiro za matenda am'magazi. Kutengera matenda am'magazi omwe mungakhale nawo komanso ziwalo zomwe zakhudzidwa, zizindikilo zanu zimatha kuphatikiza:

• Kupweteka kwa mafupa
• Kutopa
• Dzanzi kapena kumva kulasalaza m'manja ndi m'miyendo
• Lilime likutupa
• Mawanga ofiira pakhungu

Kodi chimachitika ndi chiyani poyesedwa kwaulere?

Katswiri wa zamankhwala adzatenga magazi kuchokera mumtsinje uli m'manja mwanu, pogwiritsa ntchito singano yaying'ono. Singanoyo italowetsedwa, magazi ang'onoang'ono amatengedwa mu chubu choyesera. Mutha kumva kuluma pang'ono singano ikamalowa kapena kutuluka. Izi nthawi zambiri zimatenga mphindi zosakwana zisanu.

Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?

Simukusowa kukonzekera kulikonse kwapadera kwa mayeso omasuka a unyolo.

Kodi pali zoopsa zilizonse poyesa unyolo waulere?

Pali chiopsezo chochepa kwambiri choyesedwa magazi. Mutha kukhala ndi ululu pang'ono kapena kuvulala pamalo pomwe singano idayikidwapo, koma zizindikiro zambiri zimatha msanga.

Kodi zotsatirazi zikutanthauza chiyani?

Zotsatira zanu ziwonetsa kuchuluka kwa maunyolo owala a lambda ndi kappa. Ikuperekanso kufananiza pakati pa awiriwa. Ngati zotsatira zanu sizinali zabwinobwino, zitha kutanthauza kuti muli ndi vuto la plasma, monga:

• Myeloma yambiri
• Amyloidosis
• MGUS (monoclonal gammopathy yofunika osadziwika). Izi ndizomwe mumakhala ndimapuloteni ambiri. Nthawi zambiri sizimabweretsa mavuto kapena zizindikilo, koma nthawi zina zimayamba kukhala myeloma yambiri.
• Waldenstrom macroglobulinemia (WM), khansara yamagazi oyera. Ndi mtundu wosakhala Hodgkin lymphoma.

Dziwani zambiri zamayeso a labotale, magawo owerengera, ndi zotsatira zakumvetsetsa.

Kodi pali china chilichonse chomwe ndiyenera kudziwa za kuyesedwa kwaulere kwa unyolo?

Kuyesa kwaunyolo kwaulere kumalamulidwa nthawi zambiri ndi mayeso ena, kuphatikiza kuyesa magazi, kuti zithandizire kutsimikizira kuti matendawa ndi otani.

Zolemba

1. American Cancer Society [Intaneti]. Atlanta: Bungwe la American Cancer Society Inc .; c2019. Kuyesa Kupeza Myeloma Yambiri; [yasinthidwa 2018 Feb 28; adatchulidwa 2019 Dec 21]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/testing.html
2. American Cancer Society [Intaneti]. Atlanta: Bungwe la American Cancer Society Inc .; c2019. Kodi Waldenstrom Macroglobulinemia ndi chiyani?; [yasinthidwa 2018 Jul 29; adatchulidwa 2019 Dec 21]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.cancer.org/cancer/waldenstrom-macroglobulinemia/about/what-is-wm.html
3. American Society of Hematology [Intaneti]. Washington DC: American Society of Hematology; c2019. Myeloma; [adatchula 2019 Dec 21]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.hematology.org/Patients/Cancers/Myeloma.aspx
4. International Myeloma Foundation [intaneti]. North Hollywood (CA): International Myeloma Foundation; Kumvetsetsa Kuyesedwa kwa Freelite ndi Hevylite; [adatchula 2019 Dec 21]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.myeloma.org/sites/default/files/resource/u-freelite_hevylite.pdf
5. Kuyesa kwa Labu Paintaneti [Intaneti]. Washington DC: American Association for Clinical Chemistry; c2001–2019. Maunyolo a Serum Free Light; [zasinthidwa 2019 Oct 24; adatchulidwa 2019 Dec 21]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://labtestsonline.org/tests/serum-free-light-chains
6. Chipatala cha Mayo [Intaneti]. Mayo Foundation for Medical Education and Research; c1998–2019. Matenda a monoclonal gammopathy ofunikira osadziwika (MGUS): Zizindikiro ndi zoyambitsa; 2019 Meyi 21; [adatchula 2019 Dec 21]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.mayoclinic.org/diseases-conditions/mgus/symptoms-causes/syc-20352362
7. Chipatala cha Mayo: Mayo Medical Laboratories [Internet]. Mayo Foundation for Medical Education and Research; c1995–2019. Chidziwitso Cha Mayeso: FLCP: Maunyolo Osefukira a Immunoglobulin, Seramu: Zachipatala ndi Otanthauzira; [adatchula 2019 Dec 21; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/84190
8. National Cancer Institute [Intaneti]. Bethesda (MD): U.S. Department of Health and Human Services Plasma Cell Neoplasms (Kuphatikiza Multiple Myeloma) Treatment (PDQ®) -Patient Version; [yasinthidwa 2019 Nov 8; adatchulidwa 2019 Dec 21]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq
9. National Heart, Lung, ndi Blood Institute [Internet]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Kuyesa Magazi; [adatchula 2019 Dec 21]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.nhlbi.nih.gov/health-topics/blood-tests
10. University of Rochester Medical Center [Intaneti]. Rochester (NY): Yunivesite ya Rochester Medical Center; c2019. Health Encyclopedia: Maunyolo Ounika Aulere (Magazi); [adatchula 2019 Dec 21]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=serum_free_light_chains

Zomwe zili patsamba lino siziyenera kugwiritsidwa ntchito m'malo mwa chithandizo chamankhwala kapena upangiri. Lumikizanani ndi othandizira azaumoyo ngati muli ndi mafunso okhudzana ndi thanzi lanu.