Kuyesedwa Kwachibadwa kwa Khansa ya M'mawere ya Metastatic: Mafunso Ofunsa Dokotala Wanu

Zamkati

• Kodi kuyesa majini ndi chiyani? Zimatheka bwanji?
• Kodi ndiyenera kuyezetsa majini a khansa ya m'mawere?
• Kodi kuyezetsa majini kumathandizira bwanji pachithandizo changa cha khansa ya m'mawere?
• Chifukwa chiyani kusintha kwa majini kumakhudza chithandizo? Kodi masinthidwe ena ndi 'oyipa' kuposa ena?
• Kusintha kwa PIK3CA ndi chiyani? Amachizidwa bwanji?
• Ndinawerenga za mayesero azachipatala a khansa ya m'mawere. Ngati ndili woyenera, kodi izi ndi zotetezeka?
• Kodi pali zoopsa zilizonse pakuyesedwa kwa majini?
• Zitenga nthawi yayitali bwanji kuti mupeze zotsatira kuchokera kukayezetsa majini?
• Kodi zotsatira zake zidzaperekedwa bwanji kwa ine? Ndani ati apite ndi ine zotsatira zake ndipo zikutanthauza chiyani?

Kodi kuyesa majini ndi chiyani? Zimatheka bwanji?

Kuyesedwa kwa majini ndi mtundu wa mayeso a labotale omwe amapereka chidziwitso chodziwikiratu chokhudza ngati munthu ali ndi zachilendo m'matenda awo, monga kusintha.

Kuyesaku kumachitika mu labu, makamaka ndi sampuli yamagazi a wodwalayo kapena maselo am'kamwa.

Zosintha zina zamtundu zimalumikizidwa ndi khansa zina, monga Zamgululi1 kapena Zamgululi majini a khansa ya m'mawere.

Kodi ndiyenera kuyezetsa majini a khansa ya m'mawere?

Kuyezetsa magazi kumatha kukhala kothandiza kwa aliyense amene ali ndi khansa ya m'mawere, koma sikofunikira. Aliyense atha kuyesedwa ngati akufuna atatero. Gulu lanu la oncology lingakuthandizeni kupanga chisankho.

Anthu omwe amakwaniritsa zofunikira zina atha kusintha majini. Izi zikuphatikiza:

• kukhala ochepera zaka 50
• kukhala ndi mbiri yolimba ya khansa ya m'mawere
• kukhala ndi khansa ya m'mawere m'mawere onse awiri
• kukhala ndi khansa ya m'mawere yopanda katatu

Pali njira zapadera zothandizira odwala khansa ya m'mawere omwe amayesa kusintha kwa majini, chifukwa chake onetsetsani kuti mufunse za kuyesa kwa majini.

Kodi kuyezetsa majini kumathandizira bwanji pachithandizo changa cha khansa ya m'mawere?

Chithandizo cha khansa ya m'mawere chimagwirizana ndi munthu aliyense, kuphatikiza iwo omwe ali ndi vuto lakuthwa. Kwa odwala omwe amasintha ndi kusintha kwa majini, pali njira zingapo zamankhwala zomwe angapangire.

Mwachitsanzo, mankhwala apadera monga PI3-kinase (PI3K) inhibitors amapezeka kwa anthu omwe ali ndi kusintha kwa majini PIK3CA jini ngati akwaniritsa njira zina zotengera mahomoni.

PARP inhibitors ndi njira kwa anthu omwe ali ndi khansa ya m'mawere yomwe ili ndi Zamgululi1 kapena Zamgululi kusintha kwa majini. Ziyeso zamankhwala pazithandizo izi zikupitilira. Dokotala wanu akhoza kukudziwitsani ngati mukufuna.

Chifukwa chiyani kusintha kwa majini kumakhudza chithandizo? Kodi masinthidwe ena ndi 'oyipa' kuposa ena?

Zina mwazomwe zimakhudzana ndi kusintha kwa majini zitha kulumikizidwa ndi mankhwala apadera omwe amadziwika kuti amakhudza zotsatira zake.

Kusintha kosiyanasiyana kwa majini kumalumikizidwa ndi zoopsa zosiyanasiyana. Chimodzi sichili "choyipa kwambiri" kuposa china, koma kusintha kwanu komwe kumakhudza mwachindunji chithandizo chomwe mungalandire.

Kusintha kwa PIK3CA ndi chiyani? Amachizidwa bwanji?

PIK3CA ndi jini lofunikira pakugwira ntchito kwama cell. Zovuta (mwachitsanzo, kusintha) mu jini sizimalola kuti zizichita bwino. Kafukufuku akuwonetsa kuti kusinthaku ndikofala kwa anthu omwe ali ndi khansa ya m'mawere. Ndikulimbikitsidwa kuti anthu ena, kuphatikiza omwe ali ndi khansa ya m'mawere, ayesedwe majini kuti awone ngati asintha.

Ngati muli nacho, mutha kukhala ofuna kulandira chithandizo monga PI3K inhibitor, yomwe imafotokoza makamaka za zomwe zasintha.

Ndinawerenga za mayesero azachipatala a khansa ya m'mawere. Ngati ndili woyenera, kodi izi ndi zotetezeka?

Mayesero azachipatala ndi njira yabwino kwa anthu ambiri omwe ali ndi khansa ya m'mawere. Chiyeso chimayenera kuyankha mafunso ofunika okhudza chithandizo chabwino kwambiri. Atha kukupatsirani mwayi wopeza ma protocol omwe mwina simungalandire mwanjira ina.

Pakhoza kukhala zoopsa pakuyesedwa kwamankhwala. Zoopsa zodziwika ziyenera kugawidwa nanu musanayambe. Mukadziwa zonse za kafukufukuyu ndi kuopsa kwake, muyenera kupereka chilolezo musanayambe. Gulu loyeserera nthawi zonse limayang'ana zoopsa ndikugawana zambiri zatsopano.

Kodi pali zoopsa zilizonse pakuyesedwa kwa majini?

Pali zoopsa pakuyesedwa kwa majini potengera anthu omwe akupatsidwa chidziwitso chofunikira chokhudza majini awo. Izi zitha kupangitsa nkhawa.

Pakhoza kukhalanso zopanikizika pazachuma kutengera mtundu wa inshuwaransi yanu. Muyeneranso kulingalira momwe mudzaululira uthengawu kwa abale anu. Gulu lanu losamalira lingathandize pa chisankhochi.

Zotsatira zabwino zoyeserera zitha kuwonetsanso kuti mukufunikira njira yayikulu yothandizira.

Zitenga nthawi yayitali bwanji kuti mupeze zotsatira kuchokera kukayezetsa majini?

Ndibwino kukambirana za kuyesa kwa majini ndi dokotala wanu mwachangu mukamapezeka chifukwa zotsatira zake zimatenga nthawi kuti zisinthe.

Mayeso ambiri amtundu amatenga milungu iwiri kapena 4 kuti apeze zotsatira.

Kodi zotsatira zake zidzaperekedwa bwanji kwa ine? Ndani ati apite ndi ine zotsatira zake ndipo zikutanthauza chiyani?

Nthawi zambiri, dotolo amene adalamula kuti akayezetse kapena wobadwa nawo azikupatsirani zotsatira. Izi zitha kuchitika payekha kapena pafoni.

Zimalimbikitsidwanso kuti muwone mlangizi wama genetiki kuti awunikenso zotsatira zanu.

Dr.Michelle Azu ndi dokotala wochita opaleshoni wodziwika bwino pa zamankhwala komanso matenda am'mabere. Dr. Azu anamaliza maphunziro awo ku University of Missouri-Columbia ku 2003 ndi digiri yake ya udokotala. Pakadali pano ndi director of services opaleshoni yam'chipatala cha New York-Presbyterian / Lawrence. Amagwiranso ntchito ngati pulofesa wothandizira ku Columbia University Medical Center ndi Rutgers School of Public Health. Mu nthawi yake yopuma, Dr. Azu amakonda kuyenda komanso kujambula zithunzi.