Kodi Hypokinesia ndi Chiyani Ndipo Zimakhudza Thupi?

Zamkati

• Zizindikiro zake ndi ziti?
• Zizindikiro zamagalimoto
• Zizindikiro zopanda magalimoto
• Kodi ndi zinthu ziti zomwe zimayambitsa hypokinesia?
• Kodi ndi njira ziti zamankhwala zomwe zingapezeke?
• Kodi hypokinesia ingayambitse zovuta zina zoyenda?
• Maganizo ake ndi otani?

Kodi hypokinesia ndi chiyani?

Hypokinesia ndi mtundu wamatenda oyenda. Zimatanthawuza makamaka kuti mayendedwe anu ali ndi "matalikidwe otsika" kapena sali akulu momwe mungayembekezere.

Hypokinesia ndi yokhudzana ndi akinesia, kutanthauza kuti kusayenda, komanso bradykinesia, kutanthauza kuti kuyenda pang'onopang'ono. Mawu atatuwa amasonkhanitsidwa pamodzi ndipo amatchulidwa pansi pa mawu akuti bradykinesia. Matendawa nthawi zambiri amakhala ofanana ndi matenda a Parkinson.

Hypokinesia ndiye mbali yina ya hyperkinesia. Hypokinesia imachitika mukamayendetsa pang'ono, ndipo hyperkinesia imachitika mukakhala ndi mayendedwe ambiri osagwira ntchito.

Zizindikiro zake ndi ziti?

Hypokinesia nthawi zambiri imawonedwa limodzi ndi akinesia ndi bradykinesia. Pamodzi ndi zovuta zowongolera magalimoto, kuphatikiza kwamavutowa kumatha kubweranso ndi zizindikilo zosiyanasiyana zomwe sizili zamagalimoto. Kuphatikizika kwa zizindikirazi nthawi zambiri kumalumikizidwa ndi matenda a Parkinson.

Zizindikiro zamagalimoto

Kusuntha kosazolowereka kumatha kuwonekera m'malo osiyanasiyana amthupi lanu m'njira zosiyanasiyana.

Zina mwazinthu monga:

• kuyang'ana pankhope panu (hypomimia)
• kuchepa kuphethira
• yang'anani mopanda kanthu m'maso mwanu
• mawu ofewa (hypophonia) osataya mphamvu (aprosody)
• kutsetsereka chifukwa umasiya kumeza zokha
• pewani phewa pang'onopang'ono ndikukweza mkono
• kugwedezeka kosalamulirika (kunjenjemera)
• zolemba zochepa, zochepa (micrographia)
• kuchepa kwa kugwedezeka kwa mkono poyenda
• kuyenda pang'onopang'ono, kocheperako potsegula ndikutseka manja anu kapena kugwedeza zala zanu
• kusachita bwino pakumeta, kutsuka mano, kapena kudzola mafuta
• kuyenda pang'onopang'ono, pang'ono pang'onopang'ono poponda mapazi anu kapena kugwedeza zala zanu
• kukhazikika patsogolo
• wodekha, wosuntha mozungulira
• kuvuta kuyambika kapena kuzizira pakuyenda
• kuvuta kukwera pampando, kutuluka mgalimoto yanu, ndi kugona pabedi

Zizindikiro zopanda magalimoto

Zizindikiro zamaganizidwe ndi thupi zomwe sizimayambitsa matenda a hypokinesia nthawi zambiri zimayandikira ndi hypokinesia ndi matenda a Parkinson.

Izi zikuphatikiza:

• kutaya kuthekera kwa ntchito zingapo ndikuganizira
• kuchedwa kuganiza
• kuyambika kwa matenda amisala
• kukhumudwa
• nkhawa
• psychosis kapena matenda ena amisala
• kusokonezeka kwa tulo
• kutopa
• kuthamanga kwa magazi mukaimirira
• kudzimbidwa
• ululu wosadziwika
• kutaya kununkhiza
• Kulephera kwa erectile
• dzanzi kapena kumverera kwa "zikhomo ndi singano"

Kodi ndi zinthu ziti zomwe zimayambitsa hypokinesia?

Hypokinesia imawonekera kwambiri m'matenda a Parkinson kapena ma syndromes onga a Parkinson. Ikhozanso kukhala chizindikiro cha zikhalidwe zina:

Matenda achizungu ndi zina zotha kuzindikira nthawi zambiri zimabwera ndimavuto amgalimoto monga hypokinesia. Zovuta zoyenda izi zimatha kuchitika chifukwa magawo osiyanasiyana aubongo "samalankhulana" molondola.

Dementia ndi matupi a Lewy ndi mawonekedwe amisala. Zizindikiro zimaphatikizaponso kuyerekezera zinthu m'maganizo, zovuta zamaganizidwe, zovuta zamagulu ngati hypokinesia, kugwa mobwerezabwereza, kukomoka, kusokonekera, kusowa tulo, komanso kukhumudwa.

Angapo dongosolo atrophy ndi gulu lamavuto amanjenje omwe amayambitsa hypokinesia, kusagwirizana, kusintha kwa malankhulidwe, kuuma, kufooka, kuwonongeka kwa erectile, mavuto amakodzo, komanso chizungulire akaimirira.

Kupita patsogolo kwa supranuclear palsy ndi matenda okhala ndi zizindikilo zamagalimoto ofanana ndi a Parkinson. Chizindikirocho ndi kulephera kuyendetsa maso anu mmwamba ndi pansi; Muthanso kukhala ndi vuto lotsegulira zikope zanu. Mutha kukhala ndi vuto ndi mayankhulidwe ndi kumeza, ndipo mungaganize pang'onopang'ono.

Sitiroko mu hypokinesia kapena vuto lina loyenda. Zikachitika, post-stroke hypokinesia imakhala bwino pakatha miyezi 6 mpaka 12.

Cortical basal ganglionic kuchepa ndi matenda osowa kwambiri ngati Parkinson. Mutha kukhala olimba mbali imodzi ya thupi lanu, kupweteka kwa minofu, komanso mavuto amawu. Nthawi zina mkono kapena mwendo wanu ungasunthire musanakuuzeni.

Kodi ndi njira ziti zamankhwala zomwe zingapezeke?

Muli ndi njira zambiri zochepetsera zizindikiro ndikukhalitsa moyo wabwino ngati muli ndi hypokinesia kapena matenda ena osunthika okhudzana ndi matenda a Parkinson. Njira yothandizirayi ingaphatikizepo mankhwala, kulimbikitsidwa kwa ubongo, komanso chithandizo chamankhwala.

Komabe, palibe mankhwala kapena chithandizo chomwe chilipo panthawiyi chomwe chingachedwetse kapena kuyimitsa kupita patsogolo kwa matendawa.

Ambiri mwa mankhwala ochizira magalimoto a Parkinson amachulukitsa kuchuluka kwa dopamine muubongo wanu. Mitundu ina yamankhwala ndi njira zochiritsira zimagwiritsidwa ntchito pochiza zizindikilo zomwe sizili zamagalimoto.

Zosankha zodziwika monga:

Levodopa amatembenuzidwa kukhala dopamine muubongo wanu ndipo ndiye mankhwala othandiza kwambiri a hypokinesia okhudzana ndi matenda a Parkinson. Nthawi zambiri zimaphatikizidwa carbidopa (Lodosyn), omwe ndi mankhwala omwe amaletsa kuwonongeka kwa levodopa mthupi kuti ifike kuubongo.

Agonist a Dopamine Ndi mtundu wina wa mankhwala omwe amachulukitsa kuchuluka kwanu kwa dopamine. Zitha kuphatikizidwa ndi levodopa. Mankhwalawa akuphatikizapo bromocriptine (Parlodel), pergolide (Permax), pramipexole (Mirapex), ndi ropinirole (Requip).

Monoamine oxidase (MAO) -B zoletsa chepetsani kuwonongeka kwa dopamine muubongo. Amalola kuti thupi lanu likhale ndi dopamine kuti ligwire ntchito nthawi yayitali. Mankhwalawa akuphatikizapo selegiline (Eldepryl) ndi rasagiline (Azilect).

Catechol-O-methyltransferase (COMT) zoletsa chepetsani kuwonongeka kwa levodopa mthupi, ndikulola levodopa yambiri kuti ifike kuubongo. Mankhwalawa akuphatikizapo entacapone (Comtan) ndi tolcapone (Tasmar).

Mankhwala oletsa anticholinergic kuchepetsa ubongo mankhwala acetylcholine ndikuthandizira kubwezeretsa bwino pakati pa acetylcholine ndi dopamine. Mankhwalawa akuphatikizapo trihexyphenidyl (Artane) ndi benztropine (Cogentin).

Amantadine (Symmetrel) imagwira ntchito m'njira ziwiri. Imawonjezera zochitika muubongo wanu. Zimakhudzanso dongosolo la glutamate muubongo wanu, kumachepetsa kuyenda kosalamulirika kwa thupi.

Kulimbikitsana kwa ubongo (DBS) Ndi njira yothandizira ngati njira zina zamankhwala sizikukuyenderani bwino. Zimagwira bwino ntchito kuchepetsa kuuma, kuchepa, ndi kunjenjemera.

Inu ndi adotolo mupitilira pazizindikiro zina zomwe sizingayende zomwe mungakhale nazo, monga zovuta zamaganizidwe, kutopa, kapena mavuto ogona. Pamodzi mutha kupeza njira yothandizira yomwe imaphatikizapo mankhwala ndi njira zina zothandizira kuti muchepetse zizindikilozo.

Dokotala wanu angakulimbikitseninso chithandizo chamankhwala, chithandizo chantchito, kugwiritsa ntchito zida zothandizira, kapena upangiri.

Kodi hypokinesia ingayambitse zovuta zina zoyenda?

Mitundu ingapo yamavuto oyenda imawonekera limodzi ndi mayendedwe ang'onoang'ono a hypokinesia. Mitundu yachilendo yamagalimoto imapezeka mwa munthu yemwe ali ndi matenda a Parkinson kapena amodzi mwa ma syndromes onga a Parkinson.

Zitsanzo ndi izi:

Akinesia: Ngati muli ndi akinesia, mudzakhala ndi vuto kapena kulephera kuyambitsa mayendedwe. Kuuma kwa minofu yanu kumayambira m'miyendo ndi m'khosi. Ngati akinesia imakhudza minofu yanu yakumaso, mutha kukhala ndi mawonekedwe ngati chigoba.

Bradykinesia: Ngati muli ndi bradykinesia, mayendedwe anu azachedwa. Popita nthawi, mutha kuyamba "kuzizira" pakati pa gulu ndipo zingatenge inu masekondi pang'ono kuti muyambirenso.

Dysarthria: Ngati muli ndi dysarthria, minofu yomwe mumagwiritsa ntchito polankhula idzakhala yofooka kapena mudzakhala ndi zovuta kuzilamulira. Kalankhulidwe kanu kangakhale koperewera kapena kosachedwa ndipo ena angavutike kuti akumvetseni.

Dyskinesia: Ngati muli ndi dyskinesia, mudzakhala ndi mayendedwe osalamulirika. Zitha kukhudza gawo limodzi la thupi - monga mkono wanu, mwendo, kapena mutu - kapena zingakhudze minofu mthupi lanu lonse. Dyskinesia imatha kuwoneka ngati kungoyenda, kukokota, kugwedezeka, kapena kudula mutu.

Dystonia: Ngati muli ndi dystonia, mudzakhala ndi zopweteka, zazitali zam'mimba zomwe zimayambitsa mayendedwe opindika komanso mawonekedwe achilengedwe. Zizindikirozo zimayamba m'dera limodzi koma zimafalikira kumadera ena.

Kukhwima: Ngati muli okhwima, mwendo umodzi kapena zingapo kapena ziwalo zina zimakhala zolimba modabwitsa. Ndi mbali imodzi yodziwika ya matenda a Parkinson.

Kusakhazikika kwanyengo: Mukakhala ndi kusakhazikika kwamasamba, mudzakhala ndi vuto poyesa kulumikizana bwino. Izi zitha kukupangitsani kuti musakhazikika mukayimirira kapena poyenda.

Maganizo ake ndi otani?

Palibe mankhwala a hypokinesia. Parkinson ndi matenda omwe akupita patsogolo, kutanthauza kuti adzafika poipa pakapita nthawi. Koma simungadziwitse kuti ndi ziti zomwe mungapeze kapena mudzazipeza liti. Zizindikiro zambiri zimatha kuchepetsedwa ndimankhwala ndi zina zochiritsira.

Zomwe munthu amakumana nazo ndi hypokinesia ndi matenda a Parkinson ndizosiyana. Dokotala wanu ndiye gwero lanu labwino kwambiri kuti mudziwe zambiri zamomwe mungaganizire.