Lactic Acidosis: Zomwe Muyenera Kudziwa

Zamkati

• Zizindikiro zake ndi ziti?
• Zimayambitsa ndi chiyani?
• Matenda a mtima
• Matenda oopsa (sepsis)
• HIV
• Khansa
• Matenda amfupi (matumbo amfupi)
• Ntchito ya Acetaminophen
• Kuledzera kosatha
• Kuchita masewera olimbitsa thupi kwambiri kapena kulimbitsa thupi
• Lactic acidosis ndi matenda ashuga
• Kodi amapezeka bwanji?
• Kodi njira zamankhwala ndi ziti?
• Kodi malingaliro ake ndi otani?
• Kupewa lactic acidosis

Kodi lactic acidosis ndi chiyani?

Lactic acidosis ndi mtundu wa kagayidwe kachakudya acidosis komwe kamayamba munthu akagulitsa kapena kugwiritsa ntchito lactic acid, ndipo thupi lawo silimatha kusintha kusintha kumeneku.

Anthu omwe ali ndi lactic acidosis amatha (ndipo nthawi zina impso zawo) amatha kuchotsa asidi owonjezera mthupi lawo. Ngati lactic acid imakhazikika mthupi mwachangu kuposa momwe ingachotsedwere, kuchuluka kwa acidity m'madzi amthupi - monga magazi.

Kuchuluka kwa asidi kumeneku kumayambitsa kusalinganika kwa pH ya thupi, yomwe nthawi zonse iyenera kukhala yamchere pang'ono m'malo mwa acidic. Pali mitundu ingapo ya acidosis.

Lactic acid buildup imachitika ngati mulibe oxygen yokwanira m'minyewa yothira glucose ndi glycogen. Izi zimatchedwa anaerobic metabolism.

Pali mitundu iwiri ya lactic acid: L-lactate ndi D-lactate. Mitundu yambiri ya lactic acidosis imayamba chifukwa cha L-lactate yambiri.

Pali mitundu iwiri ya lactic acidosis, Type A ndi Type B:

• Lembani A lactic acidosis amayamba chifukwa cha hypoperfusion ya minofu chifukwa cha hypovolemia, kulephera kwamtima, sepsis, kapena kumangidwa kwa mtima.
• Mtundu B lactic acidosis amayamba chifukwa cha kuwonongeka kwa magwiridwe antchito am'deralo komanso malo am'madera okhala ndi hypoperfusion ya minofu.

Lactic acidosis ili ndi zifukwa zambiri ndipo imatha kuchiritsidwa. Koma ngati sanalandire chithandizo, atha kukhala owopsa.

Zizindikiro zake ndi ziti?

Zizindikiro za lactic acidosis ndizofala pazinthu zambiri zathanzi. Ngati mukumane ndi izi, muyenera kufunsa dokotala nthawi yomweyo. Dokotala wanu akhoza kukuthandizani kudziwa zomwe zimayambitsa.

Zizindikiro zingapo za lactic acidosis zimayimira zachipatala:

• mpweya wonunkhira (womwe ungakhale vuto lalikulu la matenda ashuga, wotchedwa ketoacidosis)
• chisokonezo
• jaundice (chikasu cha khungu kapena azungu amaso)
• kuvuta kupuma kapena kupuma pang'ono, kupuma mwachangu

Ngati mukudziwa kapena mukuganiza kuti muli ndi lactic acidosis ndipo muli ndi zizindikilozi, imbani foni ku 911 kapena pitani kuchipatala mwadzidzidzi nthawi yomweyo.

Zizindikiro zina za lactic acidosis ndi monga:

• kutopa kapena kutopa kwambiri
• kukokana kwa minofu kapena kupweteka
• kufooka kwa thupi
• Kukhumudwa kwathunthu kwakuthupi
• kupweteka m'mimba kapena kusapeza bwino
• kutsegula m'mimba
• kuchepa kwa njala
• mutu
• kugunda kwamtima mwachangu

Zimayambitsa ndi chiyani?

Lactic acidosis ili ndi zifukwa zosiyanasiyana, kuphatikizapo poizoni wa carbon monoxide, kolera, malungo, ndi kupuma. Zina mwazomwe zimayambitsa ndi monga:

Matenda a mtima

Zinthu monga kumangidwa kwa mtima komanso kupindika kwa mtima kumachepetsa magazi ndi mpweya mthupi lonse. Izi zitha kuwonjezera milingo ya lactic acid.

Matenda oopsa (sepsis)

Mtundu uliwonse wamatenda akulu kapena bakiteriya amatha kuyambitsa sepsis. Anthu omwe ali ndi sepsis amatha kukhala ndi zotupa mu lactic acid, chifukwa cha kuchepa kwa mpweya.

HIV

Mankhwala a HIV, monga nucleoside reverse transcriptase inhibitors, amatha kutulutsa ma lactic acid. Zikhozanso kuwononga chiwindi. Izi zimapangitsa kuti zikhale zovuta kuti thupi lizigwiritsa ntchito lactate.

Khansa

Maselo a khansa amapanga lactic acid. Kuchuluka kwa lactic acid kumatha kupitilira pamene munthu ataya thupi ndipo matendawa amapita patsogolo.

Matenda amfupi (matumbo amfupi)

Pomwe, anthu omwe ali ndi matumbo amfupi amatha kukhala ndi kuchuluka kwa D-lactic acid, yoyambitsidwa ndi kuchuluka kwa bakiteriya m'matumbo ang'onoang'ono. Anthu omwe adachitidwa opaleshoni ya m'mimba amathanso kulandira D-lactic acidosis.

Ntchito ya Acetaminophen

Kugwiritsa ntchito acetaminophen (Tylenol) pafupipafupi kumatha kuyambitsa lactic acidosis, ngakhale mutamwa mulingo woyenera. Izi ndichifukwa choti zimatha kuyambitsa kuchuluka kwa pyroglutamic acid m'magazi.

Kuledzera kosatha

Kumwa mowa mopitirira muyeso kwa nthawi yayitali kumatha kuyambitsa lactic acidosis ndi ketoacidosis yoledzeretsa. Ketoacidosis yoledzeretsa imatha kupha ngati singalandire chithandizo, koma imatha kulimbana ndi mtsempha wa magazi (IV) hydration ndi glucose.

Mowa umawonjezera milingo ya phosphate, yomwe imakhudza impso. Izi zimapangitsa pH ya thupi kukhala yowonjezereka. Ngati mukuvutikira kuchepetsa kumwa mowa, magulu othandizira angathandize.

Kuchita masewera olimbitsa thupi kwambiri kapena kulimbitsa thupi

Kukhazikika kwakanthawi kwa lactic acid kumatha kubwera chifukwa cholimbitsa thupi mwamphamvu ngati thupi lanu lilibe mpweya wokwanira woti uwononge shuga m'magazi. Izi zitha kuyambitsa moto pakati pamagulu omwe mumagwiritsa ntchito. Zikhozanso kuyambitsa nseru komanso kufooka.

Lactic acidosis ndi matenda ashuga

Gulu linalake la mankhwala a shuga am'kamwa, otchedwa biguanides, atha kuyambitsa kuchuluka kwa milingo ya lactic acid.

Metformin (Glucophage) ndi imodzi mwa mankhwalawa. Amagwiritsidwa ntchito pochiza matenda ashuga ndipo amathanso kulembedwa pazinthu zina, monga kusowa kwa impso. Metformin imagwiritsidwanso ntchito ngati chizindikiro pochiza matenda a polycystic ovarian.

Mwa anthu omwe ali ndi matenda ashuga, lactic acidosis itha kukhala yovuta kwambiri ngati matenda a impso alipo. Ngati muli ndi matenda ashuga ndipo mukukumana ndi vuto lililonse la lactic acidosis, itanani 911 kapena pitani kuchipatala mwadzidzidzi.

Kodi amapezeka bwanji?

Lactic acidosis imapezeka kudzera pakuyesa magazi mwachangu. Dokotala wanu akhoza kukulangizani kuti musadye kapena kumwa chilichonse kwa maola 8 kapena 10 musanayezetse. Muthanso kulangizidwa kuti muchepetse magwiridwe antchito anu m'maola omwe akutsogolera mayeso.

Mukamayesa, adokotala angakuuzeni kuti musamange nkhonya, chifukwa izi zitha kupangitsa kuchuluka kwa asidi. Kumangiriza lamba pamanja kungathenso kukhala ndi zotsatirazi.

Pazifukwa izi, kuyezetsa magazi kwa lactic acidosis nthawi zina kumachitika chifukwa chopeza mtsempha kumbuyo kwa dzanja m'malo mwa mkono.

Kodi njira zamankhwala ndi ziti?

Njira yabwino kwambiri yochizira lactic acidosis ndikuthandizira zomwe zimayambitsa. Pachifukwachi, mankhwala amasiyana.

Lactic acidosis nthawi zina imayimira zachipatala. Izi zimafunikira kuchiza zizindikiritso, mosatengera zomwe zimayambitsa. Kuchulukitsa mpweya kumatumba ndikupatsanso madzi amadzimadzi a IV amagwiritsidwa ntchito pochepetsa asidi wa lactic.

Lactic acidosis yoyambitsa masewera olimbitsa thupi imatha kuchiritsidwa kunyumba. Kuyimitsa zomwe mukuchita kuti mupumule ndikupumula, nthawi zambiri kumathandiza. Zakumwa zamasewera zosinthira zamagetsi, monga Gatorade, zimathandiza ndi madzi, koma madzi nthawi zambiri amakhala abwino.

Kodi malingaliro ake ndi otani?

Kutengera pazomwe zimayambitsa, chithandizo cha lactic acidosis nthawi zambiri chimachira, makamaka ngati chithandizo chikufulumira. Nthawi zina, kulephera kwa impso kapena kupuma kungachitike. Ngati sanalandire chithandizo, lactic acidosis imatha kupha.

Kupewa lactic acidosis

Kupewa kwa Lactic acidosis kumatsimikizidwanso ndi zomwe zingayambitse. Ngati muli ndi matenda a shuga, HIV, kapena khansa, kambiranani za matenda anu komanso mankhwala omwe mukufuna ndi dokotala wanu.

Lactic acidosis yochita masewera olimbitsa thupi itha kupewedwa ndikukhala ndi hydrated ndikudzipumulira nthawi yayitali pakati pazochita zolimbitsa thupi.

Ndikofunika kwambiri kupewa kumwa mowa mopitirira muyeso. Kambiranani za njira zakukonzanso ndi magawo 12 ndi dokotala kapena mlangizi.