Latuda (lurasidone): ndi chiani, momwe mungamwere ndi zotsatirapo zake
Zamkati
Lurasidone, wodziwika ndi dzina lantchito Latuda, ndi mankhwala m'kalasi la ma antipsychotic, omwe amagwiritsidwa ntchito pochiza matenda a schizophrenia ndi kukhumudwa komwe kumachitika chifukwa cha matenda osokoneza bongo.
Mankhwalawa adavomerezedwa posachedwapa ndi Anvisa ogulitsa m'masitolo ku Brazil, 20mg, 40mg ndi 80mg mapiritsi, m'mapaketi a mapiritsi 7, 14, 30 kapena 60, ndipo amatha kupezeka kapena kuyitanidwa m'masitolo akuluakulu. Popeza ndi antipsychotic, Lurasidone ndi gawo limodzi la mankhwala omwe amagulitsidwa ndipo amangogulitsidwa ndi mankhwala apadera m'makope awiri.
Ndi chiyani
Lurasidone imagwiritsidwa ntchito pochiza:
- Schizophrenia, mwa akulu ndi achinyamata azaka zapakati pa 13 mpaka 18;
- Matenda okhumudwa omwe amabwera chifukwa cha kupuma, mwa akulu, ngati mankhwala amodzi kapena mogwirizana ndi ena, monga lithiamu kapena valproate.
Mankhwalawa ndi antipsychotic, omwe amachita ngati njira yolepheretsa zotsatira za dopamine ndi monoamine, omwe ndi ma neurotransmitters aubongo, ofunikira pakukonzanso zizindikilo.
Komabe, imagwira ntchito ndi zina zotsogola poyerekeza ndi ma antipsychotic achikulire, monga kusintha pang'ono pakapangidwe kazakudya, kukhala ndi zotsatira zochepa pakulemera komanso kusintha kwamafuta amthupi ndi shuga.
Momwe mungatenge
Mapiritsi a Lurasidone ayenera kumamwa pakamwa, kamodzi patsiku, limodzi ndi chakudya, ndipo tikulimbikitsidwa kuti azimwa nthawi yomweyo. Kuphatikiza apo, mapiritsiwa ayenera kumezedwa kwathunthu, kupewa kukoma kwawo.
Zotsatira zoyipa
Zotsatira zoyipa kwambiri za Lurasidone ndi kusowa tulo, kusakhazikika, chizungulire, mayendedwe osachita chilichonse, kusowa tulo, kusokonezeka, nkhawa kapena kunenepa.
Zina zomwe zingachitike ndi kugwidwa, kuchepa kwa njala, kutopa, kusawona bwino, tachycardia, kusintha kwa kuthamanga kwa magazi, chizungulire kapena kusintha kwa kuchuluka kwa magazi, mwachitsanzo.
Yemwe sayenera kutenga
Lurasidone imatsutsana pamaso pa:
- Hypersensitivity kwa chinthu chogwiritsidwa ntchito kapena china chilichonse chowonjezera pa piritsi;
- Kugwiritsa ntchito mankhwala osokoneza bongo a CYP3A4, monga Boceprevir, Clarithromycin, Voriconazole, Indinavir, Itraconazole kapena Ketoconazole, mwachitsanzo;
- Kugwiritsa ntchito mankhwala osokoneza bongo a CYP3A4, monga Carbamazepine, Phenobarbital, Phenytoin, Rifampicin kapena St. John's wort, mwachitsanzo.
Chifukwa chothandizana ndi mankhwalawa, mndandanda wa mankhwala omwe amagwiritsidwa ntchito ayenera kudziwitsidwa kwa dokotala yemwe akutsatira.
Lurasidone iyenera kugwiritsidwa ntchito mosamala ndi anthu omwe ali ndi matenda a impso kapena matenda owopsa a chiwindi, matenda a Parkinson, zovuta zamagulu, matenda amtima kapena matenda amanjenje. Kuphatikiza apo, mankhwalawa sanayesedwe kwa odwala okalamba omwe ali ndi matenda amisala kapena ana, chifukwa chake kugwiritsa ntchito kuyenera kupewedwa pazochitikazi.