Medullary Carcinoma ya M'chifuwa

Zamkati

• Kodi zizindikiro za medullary carcinoma ya m'mawere ndi ziti?
• Nchiyani chimayambitsa medullary carcinoma ya m'mawere?
• Kodi ndi zoopsa ziti za medullary carcinoma?
• Kodi njira zamankhwala za medullary carcinoma za m'mawere ndi ziti?
• Kodi matenda am'mimba am'mamankhwala amapezeka bwanji?
• Kodi malingaliro akuti medullary carcinoma a m'mawere ndi ati?
• Kodi malingaliro a medullary carcinoma a m'mawere ndi otani?

Chidule

Medullary carcinoma ya m'mawere ndi gawo laling'ono la ductal carcinoma. Ndi mtundu wa khansa ya m'mawere yomwe imayamba mumayendedwe amkaka. Khansara ya m'mawere imeneyi imadziwika chifukwa chotupacho chimafanana ndi gawo la ubongo lotchedwa medulla. Medullary carcinoma ya m'mawere imayimira pafupifupi 3 mpaka 5 peresenti ya onse omwe amapezeka ndi khansa ya m'mawere.

Medullary carcinoma nthawi zambiri imafalikira ku ma lymph node ndipo imamvera chithandizo chamankhwala kuposa mitundu yodziwika bwino ya khansa ya m'mawere. Kuzindikira koyambirira kumeneku kumatha kukonza zamankhwala osokoneza bongo ndikuchepetsa kufunikira kwa chithandizo chowonjezera kupatula kuchotsa chotupacho.

Kodi zizindikiro za medullary carcinoma ya m'mawere ndi ziti?

Nthawi zina medullary carcinoma imatha kuyambitsa zizindikilo zochepa. Mkazi akhoza kuyamba kuwona chotupa m'chifuwa chake. Medullary carcinoma ya m'mawere imakonda kugawa maselo a khansa mwachangu. Chifukwa chake, azimayi ambiri amatha kuzindikira kuchuluka kwa bere lawo lomwe limatha kukula. Chotupacho chimakhala chofewa komanso chofewa, kapena cholimba mpaka kukhudza ndi malire. Ma carcinomas ambiri am'munsi amakhala ochepera masentimita awiri kukula.

Amayi ena amatha kukhala ndi zizindikilo zina zokhudzana ndi medullary carcinoma, kuphatikiza:

• chikondi cha m'mawere
• ululu
• kufiira
• kutupa

Ngati mukukumana ndi izi, muyenera kupita kukaonana ndi dokotala.

Nchiyani chimayambitsa medullary carcinoma ya m'mawere?

Pachikhalidwe, zotupa za khansa za m'mawere zimatha kukhala ndi mphamvu m'thupi. Medullary carcinoma ya m'mawere, komabe, nthawi zambiri sichimakhudzidwa ndi mahomoni. M'malo mwake, mzimayi amasintha kusintha kwamaselo am'mabere mwake. Izi zimapangitsa kuti maselo amakula mosalamulirika (khansa). Madokotala sakudziwa chifukwa chake kusinthaku kumachitika kapena momwe zimakhudzira medullary carcinoma ya m'mawere.

Kodi ndi zoopsa ziti za medullary carcinoma?

Amayi ena omwe ali ndi kusintha kwa majini otchedwa BRCA-1 ali pachiwopsezo chachikulu chopezeka ndi medullary carcinoma ya m'mawere, malinga ndi a Johns Hopkins Medicine. Jini imeneyi imakonda kuyenda m'mabanja. Chifukwa chake, ngati mayi ali ndi mbiri yokhudza khansa ya m'mawere mwa abale ake apafupi, ali pachiwopsezo chachikulu chotenga matendawa. Komabe, ngati mayi ali ndi jini iyi, izi sizitanthauza kuti apeza ma medullary carcinoma wa m'mawere.

Kuzindikira kwa medullary carcinomas kuli pakati pa zaka 45 ndi 52. Izi zimakhala zazing'ono kwambiri kuposa azimayi omwe amapezeka ndi medullary carcinomas, omwe amapezeka ali ndi zaka 55 kapena kupitilira apo.

Kodi njira zamankhwala za medullary carcinoma za m'mawere ndi ziti?

Dokotala amatha kuyesa njira zingapo zamankhwala zamankhwala a medullary carcinoma. Adzaganizira kukula kwa chotupacho, mtundu wa selo, ndipo ngati chotupacho chafalikira kumatenda apafupi. Chifukwa chotupacho nthawi zambiri sichimafalikira, madokotala ena amalimbikitsa kuti achotse chotupacho osangotsata chithandizo chilichonse. Izi ndizowona pomwe chotupacho ndi "medullary yoyera" ndipo chimangokhala ndi maselo omwe amafanana ndi medullary carcinoma.

Komabe, adokotala amalimbikitsanso kuchotsa chotupacho komanso mitundu ina ya chithandizo cha khansa. Izi ndizowona pomwe khansara itha kukhala ndi "ma medullary features". Izi zikutanthauza kuti maselo ena amawoneka ngati medullary carcinoma pomwe ena amawoneka ngati olanda ductal cell carcinoma. Dokotala angalimbikitsenso mankhwala ena ngati khansara yafalikira ku ma lymph node. Mankhwalawa atha kuphatikizira chemotherapy (mankhwala opha maselo omwe akukula mwachangu) kapena radiation.

Mankhwala ena omwe amagwiritsidwa ntchito kale pochiza khansa ya m'mawere nthawi zambiri sagwira bwino ntchito pa medullary carcinoma ya m'mawere. Izi zimaphatikizapo mankhwala okhudzana ndi mahomoni monga tamoxifen kapena aromatase inhibitors. Khansa ya m'mawere yambiri ndi khansa "yopanda katatu". Izi zikutanthauza kuti khansara siyankha ma hormone progesterone ndi / kapena estrogen kapena protein ina yotchedwa HER2 / neu protein.

Kodi matenda am'mimba am'mamankhwala amapezeka bwanji?

Chifukwa medullary carcinoma ya m'mawere ndiyosowa kwambiri, madokotala amatha kukhala ndi vuto poyesa kuzindikira mtundu wa khansa. Amatha kuzindikira chotupa cha m'mawere pa mammogram, yomwe ndi mtundu wapadera wa kujambula kwa X-ray komwe kumagwiritsidwa ntchito poyesa bere. Chotupacho nthawi zambiri chimakhala chozungulira kapena chowulungika ndipo sichikhala ndi malire oyenera. Dokotala amathanso kuyitanitsa maphunziro ena ojambula. Izi zitha kuphatikizira kusanthula kwa ultrasound kapena magnetic resonance imaging (MRI).

Ma medullary carcinomas a m'mawere amatha kukhala osiyana ndi matendawa. Nthawi zina, mzimayi amatha kuzindikira zotupa za khansa kudzera pakumverera, kuposa zomwe zimawoneka paphunziro lazithunzi. Pachifukwa ichi, ndikofunikira kuti mayi azidziyesa mabere mwezi uliwonse, komwe amamverera minofu yake ya m'mawere ndi nsonga zamabele.

Ngati dokotala atazindikira chotupa pogwira kapena kujambula, atha kunena kuti biopsy ya chotupacho. Izi zimaphatikizapo kuchotsa ma cell kapena chotupa chokha kuti chikayesedwe. Dokotala yemwe amachita bwino kupenda ma cell kuti akumane ndi zovuta amadziwika kuti ndi matenda. Wodwala amafufuza ma cell pansi pa microscope. Maselo a khansa ya Medullary amakhalanso ndi kusintha kwa majini p53. Kuyesedwa kwa kusinthaku kumatha kuthandizira kupeza matenda a medullary carcinoma, ngakhale kuti si mitundu yonse ya khansa yamankhwala omwe ali ndi kusintha kwa p53.

Kodi malingaliro akuti medullary carcinoma a m'mawere ndi ati?

Kuchuluka kwa zaka zisanu za medullary carcinoma ya m'mawere kumakhala kulikonse kuyambira 89 mpaka 95 peresenti. Izi zikutanthauza kuti zaka zisanu atapezeka ndi matendawa, azimayi 89 mpaka 95 mwa amayi 100 aliwonse omwe ali ndi khansa akadali ndi moyo.

Kodi malingaliro a medullary carcinoma a m'mawere ndi otani?

Medullary carcinoma ya m'mawere imakonda kuyankha bwino kuchipatala cha khansa ya m'mawere kuposa mitundu ina ya ma ductal carcinomas. Ndi kuzindikira koyambirira ndi chithandizo chamankhwala, kuyerekezera matendawa komanso kuchuluka kwa moyo ndizabwino.