Kodi Matenda a Parkinson Angayambitse Zolakwika?

Zamkati

• Kulumikizana pakati pa matenda a Parkinson ndi kuyerekezera zinthu m'maganizo
• Mitundu yazolowera
• Zosokonezeka kuchokera ku matenda a Parkinson
• Kutalika kwa moyo
• Ndi mankhwala ati omwe amapezeka ku Parkinson's psychosis?
• Mankhwala othandizira kuchiza matenda a Parkinson psychosis
• Zomwe zimayambitsa kuyerekezera zinthu m'maganizo ndi zonyenga?
• Mankhwala
• Kusokonezeka maganizo
• Delirium
• Matenda okhumudwa
• Zoyenera kuchita ngati wina ali ndi malingaliro kapena zosokoneza
• Tengera kwina

Zolota komanso zopeka zimakhala zovuta za matenda a Parkinson (PD). Amatha kukhala ovuta mokwanira kusankhidwa kukhala PD psychosis.

Malingaliro olingalira ndi malingaliro omwe sali kwenikweni pamenepo. Zosokonekera ndi zikhulupiriro zomwe sizili zenizeni. Chitsanzo chimodzi ndi paranoia yomwe imapitilira ngakhale munthu akapatsidwa umboni wosiyana.

Zolingalira zamkati mwa PD zitha kukhala zowopsa komanso zofooketsa.

Pali zinthu zambiri zomwe zingayambitse kuyerekezera zinthu mwa anthu omwe ali ndi PD. Koma milandu yambiri imachitika ngati zovuta za mankhwala a PD.

Kulumikizana pakati pa matenda a Parkinson ndi kuyerekezera zinthu m'maganizo

Zolota komanso zosokonekera mwa anthu omwe ali ndi PD nthawi zambiri zimakhala gawo la psych psychosis.

Psychosis imafala kwambiri kwa anthu omwe ali ndi PD, makamaka omwe ali kumapeto kwa matendawa. Ofufuzawo akuti zimachitika kwa anthu omwe ali ndi PD.

Onetsani kuti zizindikilo za psychosis ndizokhudzana ndi zochitika zapamwamba zamagulu amubongo otchedwa dopamine. Izi nthawi zambiri zimachitika chifukwa cha mankhwala omwe amagwiritsidwa ntchito pochiza PD.

Komabe, chifukwa chomwe anthu ena omwe ali ndi PD amadwala matenda amisala pomwe ena samamvetsetsa mpaka pano.

Mitundu yazolowera

Malingaliro ambiri okhala ndi PD amakhala ochepa ndipo samakhala ovulaza. Zitha kukhala zowopsa kapena zosokoneza, komabe, makamaka ngati zimachitika pafupipafupi.

Ziwerengero zitha kukhala:

• zowoneka (zowoneka)
• anamva (zomvetsera)
• kununkhiza (zowonjezera)
• anamva (wogwira)
• kulawa (gustatory)

Zosokonezeka kuchokera ku matenda a Parkinson

Zosokoneza zimakhudza pafupifupi 8% ya anthu omwe ali ndi PD. Zisokonezo zimakhala zovuta kwambiri kuposa kuyerekezera zinthu m'maganizo. Atha kukhala ovuta kuwachiritsa.

Zosokonekera nthawi zambiri zimayamba ngati chisokonezo chomwe chimayamba kukhala malingaliro omveka bwino osakhazikika pazowona. Zitsanzo zamitundu yachinyengo yomwe anthu omwe ali ndi chidziwitso cha PD ndi awa:

• Nsanje kapena kukhala ndi katundu. Munthuyo amakhulupirira kuti wina m'moyo wawo ndiwosakhulupirika kapena wosakhulupirika.
• Kuzunza. Amakhulupirira kuti winawake akufuna kuwapeza kapena kuwavulaza mwanjira ina.
• Somatic. Amakhulupirira kuti ali ndi vuto kapena vuto lina lachipatala.
• Kudziimba Mlandu. Yemwe ali ndi PD amadzimva kuti ndi wolakwa osati chifukwa cha machitidwe kapena zochita zenizeni.
• Zonyenga zosakanikirana. Amakumana ndi zinyengo zambiri.

Paranoia, nsanje, ndi kuzunza ndizofalitsa zomwe zimafotokozedwa kwambiri. Amatha kukhala pachiwopsezo choteteza osamalira komanso kwa munthu yemwe ali ndi PD iwowo.

Kutalika kwa moyo

PD siyowopsa, ngakhale zovuta zamatenda zimatha kupangitsa kuti moyo uzikhala waufupi.

Matenda a dementia ndi zisonyezo zina zama psychosis monga kuyerekezera zinthu m'maganizo ndi zonyenga zimathandizira kukulitsa zipatala komanso.

Kafukufuku wina wochokera ku 2010 adapeza kuti anthu omwe ali ndi PD omwe adakumana ndi zonyenga, kuyerekezera zinthu m'maganizo, kapena zizindikilo zina zama psychosis anali pafupi kufa msanga kuposa omwe alibe izi.

Koma kupewa koyambirira kwakukula kwa zizindikiritso zama psychosis kumathandizira kukulitsa chiyembekezo cha moyo kwa anthu omwe ali ndi PD.

Ndi mankhwala ati omwe amapezeka ku Parkinson's psychosis?

Dokotala wanu akhoza kuyamba kuchepetsa kapena kusintha mankhwala a PD omwe mumamwa kuti muwone ngati izi zimachepetsa zizindikiritso zama psychosis. Izi ndikuti mupeze malire.

Anthu omwe ali ndi PD angafunike kuchuluka kwa mankhwala a dopamine kuti athandizire kuthana ndi zizindikilo zamagalimoto. Koma zochitika za dopamine siziyenera kuwonjezeka kwambiri kotero kuti zimabweretsa kuyerekezera kwachinyengo ndi kusokeretsa. Dokotala wanu adzagwira nanu ntchito kuti mupeze malirewo.

Mankhwala othandizira kuchiza matenda a Parkinson psychosis

Dokotala wanu angaganize zoperekera mankhwala oletsa antipsychotic ngati kuchepetsa mankhwala anu a PD sikuthandizira kuthana ndi zotsatirazi.

Mankhwala a antipsychotic ayenera kugwiritsidwa ntchito mosamala kwambiri kwa anthu omwe ali ndi PD. Zitha kuyambitsa zovuta zoyipa ndipo zitha kupangitsanso kuyerekezera zinthu zopanda pake kapena kunyengerera.

Mankhwala omwe amachiritsa antipsychotic monga olanzapine (Zyprexa) amatha kupititsa patsogolo malingaliro, koma nthawi zambiri amachititsa kuti zizindikilo za PD zikule.

Clozapine (Clozaril) ndi quetiapine (Seroquel) ndi mankhwala ena awiri opatsirana ndi ma psychotic omwe madokotala nthawi zambiri amawapatsa pamlingo wochepa kuti athetse PD psychosis. Komabe, pali nkhawa zokhudzana ndi chitetezo chawo komanso kuchita bwino kwawo.

Mu 2016, adavomereza mankhwala oyamba omwe angagwiritsidwe ntchito mu PD psychosis: pimavanserin (NuPlazid).

Mu, pimavanserin adawonetsedwa kuti amachepetsa pafupipafupi komanso kuopsa kwa kuyerekezera zinthu kopusitsa komanso kuwonongeka popanda kukulitsa zizindikilo zoyambira za PD.

Mankhwalawa sayenera kugwiritsidwa ntchito kwa anthu omwe ali ndi matenda amisala chifukwa changozi yakufa.

Zizindikiro zama psychosis zomwe zimachitika chifukwa cha delirium zimatha kusintha pokhapokha ngati vutoli lathandizidwa.

Zomwe zimayambitsa kuyerekezera zinthu m'maganizo ndi zonyenga?

Pali zifukwa zingapo zomwe munthu yemwe ali ndi PD amatha kuwona zabodza kapena kuyerekezera zinthu.

Mankhwala

Anthu omwe ali ndi PD nthawi zambiri amayenera kumwa mankhwala angapo. Mankhwalawa amathandizira kuchiza PD ndi zina zomwe zimakhudzana ndi ukalamba. Komabe, mankhwalawa amatha kukhala ndi zovuta zambiri.

Kutenga mankhwala omwe amakhudza ma dopamine receptors ndi chiopsezo chachikulu. Izi ndichifukwa choti mankhwala ena a PD amakulitsa zochitika za dopamine. Ntchito yayikulu ya dopamine imatha kubweretsa malingaliro ndi zizindikiritso mwa anthu omwe ali ndi PD.

Mankhwala omwe angapangitse kuyerekezera kapena kusokonekera kwa anthu omwe ali ndi PD ndi awa:

• amantadine (Symmetrel)
• Mankhwala oletsa kulanda
• anticholinergics, monga trihexyphenidyl (Artane) ndi benztropine
  mesylate (Cogentin)
• carbidopa / levodopa (Sinemet)
• COMT inhibitors, monga entacapone (Comtan) ndi tolcapone (Tasmar)
• dopamine agonists, kuphatikiza rotigotine (NeuPro), pramipexole
  (Mirapex), ropinirole (Requip), pergolide (Permax), ndi bromocriptine
  (Parlodel)
• MaO-B inhibitors, monga selegiline (Eldepryl, Carbex) ndi rasagiline (Azilect)
• mankhwala okhala ndi codeine kapena morphine
• NSAID, monga ibuprofen (Motrin IB, Advil)
• mankhwala ogonetsa
• mankhwala

Kusokonezeka maganizo

Kusintha kwamankhwala komanso kwakuthupi muubongo kumathandizira pakuyerekeza ndi kuyerekezera zinthu. Izi zimawoneka kawirikawiri mukamakhala ndi matenda amisala ndi matupi a Lewy. Matupi a Lewy ndimadontho achilendo otchedwa alpha-synuclein.

Puloteni iyi imamangidwa m'malo am'magazi omwe amalamulira:

• khalidwe
• kuzindikira
• mayendedwe

Chizindikiro chimodzi cha vutoli chimakhala ndi zovuta komanso zowoneka bwino.

Delirium

Kusintha kwamalingaliro kapena kuzindikira kwa munthu kumayambitsa kusokonekera. Pali zochitika zambiri zomwe zimatha kuyambitsa gawo lakanthawi lazachisokonezo.

Anthu omwe ali ndi PD amamvetsetsa kusintha kumeneku. Zitha kuphatikiza:

• kusintha kwa malo kapena malo osadziwika
• matenda
• Kusamvana kwa electrolyte
• malungo
• mavitamini
• kugwa kapena kuvulala kumutu
• ululu
• kusowa kwa madzi m'thupi
• vuto lakumva

Matenda okhumudwa

Kukhumudwa pakati pa anthu omwe ali ndi PD ndizofala. Ochita kafukufuku akuti pafupifupi anthu 50 pa 100 aliwonse omwe ali ndi PD adzadwala matenda ovutika maganizo. Kuvulala kwa matenda a PD kumatha kuwononga thanzi lam'mutu ndi malingaliro amunthu.

Anthu omwe ali ndi vuto lalikulu lachisokonezo amathanso kukhala ndi zizindikilo za psychosis, kuphatikizapo kuyerekezera zinthu m'maganizo. Izi zimatchedwa kukhumudwa kwa psychotic.

Anthu omwe ali ndi PD omwe ali ndi nkhawa amatha kumwa mowa mwauchidakwa kapena zinthu zina. Izi zingayambitsenso magawo a psychosis.

Antidepressants atha kugwiritsidwa ntchito kuthana ndi kukhumudwa kwa anthu omwe ali ndi PD. Mankhwala omwe amagwiritsidwa ntchito kwambiri mu PD ndi serotonin reuptake inhibitors (SSRIs), monga fluoxetine (Prozac).

Zoyenera kuchita ngati wina ali ndi malingaliro kapena zosokoneza

Kukangana ndi munthu yemwe ali ndi malingaliro kapena kunyengerera sikothandiza kwenikweni. Zabwino zomwe mungachite ndikuyesera kukhala odekha ndikuvomereza malingaliro amunthuyo.

Cholinga ndikuchepetsa nkhawa zawo kuti asachite mantha.

Psychosis ndi vuto lalikulu. Zitha kupangitsa kuti munthu adzivulaze kapena kuvulaza ena. Malingaliro ambiri mwa anthu omwe ali ndi PD amawoneka. Siziwopseza moyo nthawi zambiri.

Njira ina yothandizira ndikulemba zolemba pazizindikiro za munthuyo, monga zomwe anali kuchita zisanachitike kuyerekezera zinthu zabodza kapena zonyenga, komanso malingaliro amtundu wanji omwe amati amadzakumana nawo. Kenako mutha kugawana nawo izi komanso adotolo awo.

Anthu omwe ali ndi PD psychosis amakonda kukhala chete pazomwe akumana nazo ngati izi, koma ndikofunikira kuti gulu lawo lazachipatala limvetsetse zizindikiritso zawo zonse.

Tengera kwina

Ndikofunika kudziwa kuti kukumana ndi kuyerekezera zinthu m'maganizo kapena kusokonekera chifukwa cha PD sikutanthauza kuti munthu ali ndi matenda amisala.

Nthawi zambiri, PD psychosis ndi zotsatira zoyipa za mankhwala ena a PD.

Lankhulani ndi dokotala wanu ngati inu kapena munthu amene mukumusamalira akukumana ndi malingaliro.

Ngati zizindikiro za psychosis sizikusintha ndikusintha kwa mankhwala, dokotala akhoza kukupatsani mankhwala ochepetsa matenda a psychotic.