Zizindikiro za Parkinson: Amuna ndi Akazi
Zamkati
- Kupereka zizindikiro
- Mphamvu zamaganizidwe ndi kusuntha kwa minofu
- Kufotokozera ndi kutanthauzira kutengeka
- Kusiyana kogona
- Kuteteza kwa Estrogen
- Mavuto azithandizo
- Kulimbana ndi PD
Matenda a Parkinson mwa amuna ndi akazi
Amuna ambiri kuposa akazi amapezeka ndi matenda a Parkinson (PD) pafupifupi 2 mpaka 1 malire. Kafukufuku angapo amathandizira nambalayi, kuphatikiza kafukufuku wamkulu mu American Journal of Epidemiology.
Nthawi zambiri pamakhala chifukwa chakuthupi chosiyanitsa matenda pakati pa abambo ndi amai. Kodi kukhala mkazi kumateteza bwanji ku PD? Ndipo kodi azimayi ndi abambo amakumana ndi zizindikiro za PD mosiyana?
Kupereka zizindikiro
Amayi amakhala ndi PD pafupipafupi kuposa amuna. Akayamba PD, zaka zoyambira zimakhala zaka ziwiri pambuyo pake kuposa amuna.
Akazi akapezeka koyamba, kunjenjemera kumakhala chizindikiro chachikulu. Chizindikiro choyambirira mwa amuna nthawi zambiri chimakhala kuyenda pang'onopang'ono kapena kolimba (bradykinesia).
Mtundu waukulu wa PD umalumikizidwa ndi kuchepa kwa matenda komanso moyo wabwino.
Komabe, amayi nthawi zambiri amafotokoza kukhutira pang'ono ndi moyo wawo, ngakhale ali ndi zofananira.
Mphamvu zamaganizidwe ndi kusuntha kwa minofu
PD imatha kukhudza mphamvu zamaganizidwe ndi mphamvu komanso kuwongolera minofu.
Pali umboni wina wosonyeza kuti abambo ndi amai amakhudzidwa mosiyanasiyana. Mwachitsanzo, abambo amawoneka kuti ali ndi kuthekera kwakumvetsetsa komwe kumakhala malo. Akazi, kumbali inayo, amasunga mawu momasuka.
Maluso amtunduwu samakhudzidwa ndi kugonana kokha, komanso ndi "mbali" ya zizindikilo za PD. Chizindikiro chakumanzere kapena chakumanja chakuwonekera kwa chizindikiro chikuwonetsa mbali yomwe ubongo uli ndi vuto lalikulu kwambiri la dopamine.
Mwachitsanzo, mutha kukhala ndi zovuta zambiri pakulamulira minofu kumanzere kwa thupi lanu ngati muli ndi vuto la dopamine kumanja kwa ubongo wanu.
Maluso osiyanasiyana, monga kuthekera kwa malo, amapezeka kwambiri mbali ina yaubongo.
Kufotokozera ndi kutanthauzira kutengeka
Kukhazikika kwa PD kumatha kupangitsa minofu ya nkhope "kuzizira." Izi zimabweretsa mawu ngati chigoba. Zotsatira zake, odwala omwe ali ndi PD amavutika kufotokoza mawonekedwe awo ndi nkhope zawo. Nawonso atha kukhala ndi zovuta kumasulira nkhope ya ena.
Kafukufuku wina akuwonetsa kuti amuna ndi akazi omwe ali ndi PD amatha kukhala ndi vuto lotanthauzira mkwiyo ndi kudabwitsidwa, ndikuti amuna atha kutaya kutanthauzira mantha.
Komabe, azimayi atha kukhumudwa kwambiri chifukwa cholephera kumasulira zomwe akumva. Odwala onse a PD atha kupindula ndi kulankhula ndi chithandizo chamankhwala kuti athandizire chizindikirochi.
Kusiyana kogona
Matenda ofulumira kuyenda kwamaso (RBD) ndi vuto la kugona lomwe limachitika panthawi yogona ya REM.
Nthawi zambiri, munthu amene wagona alibe minofu ndipo samasuntha atagona. Mu RBD, munthu amatha kusuntha miyendo ndikuwoneka kuti akuchita maloto awo.
RBD imachitika kawirikawiri, koma nthawi zambiri mwa anthu omwe ali ndi matenda amanjenje. Pafupifupi 15 peresenti ya anthu omwe ali ndi PD alinso ndi RBD, malinga ndi Internal Review of Psychiatry. Amuna nthawi zambiri amakhala ndi vutoli kuposa akazi.
Kuteteza kwa Estrogen
Chifukwa chiyani pali kusiyana pakati pazizindikiro za PD pakati pa abambo ndi amai? Zikuwoneka kuti kutulutsa kwa estrogen kumateteza azimayi ku kupita patsogolo kwa PD.
Kafukufuku wofalitsidwa kuti anapeza kuti mayi yemwe amakumana ndi kusintha kwa msambo, kapena amakhala ndi ana ambiri, amatha kuchedwa kuyamba kwa zizindikilo za PD. Izi zonse ndizizindikiro zakuwonetsedwa kwa estrogen m'moyo wake wonse.
Zomwe sizinafotokozeredwe bwino ndichifukwa chake estrogen ili ndi izi. Kafukufuku ku American Journal of Psychiatry awonetsa kuti azimayi ali ndi dopamine yochulukirapo m'malo ofunikira aubongo. Estrogen itha kukhala ngati neuroprotectant yantchito ya dopamine.
Mavuto azithandizo
Amayi omwe ali ndi PD amatha kukumana ndi mavuto ambiri akamachiza matenda awo a PD kuposa amuna.
Amayi amachitidwa maopareshoni pafupipafupi kuposa momwe amachitira amuna, ndipo zizindikilo zawo zimakhala zovuta kwambiri nthawi yomwe amachitidwa opaleshoni. Komanso, kusintha komwe kwachitika chifukwa cha opaleshoni sikungakhale kwakukulu.
Mankhwala osokoneza bongo amathandizanso azimayi mosiyanasiyana. Chifukwa chochepa thupi, amayi nthawi zambiri amakhala ndi mankhwala owonjezera. Ili lakhala vuto ndi levodopa, mankhwala omwe amapezeka kwambiri ku PD.
Kuwonetsedwa kwapamwamba kumatha kubweretsa kuchuluka kwa zovuta zoyipa, monga dyskinesia. Dyskinesia ndizovuta kuchita kuyenda mwaufulu.
Kulimbana ndi PD
Amuna ndi akazi nthawi zambiri amakhala ndi mayankho osiyanasiyana pazomwe amakhala ndi PD.
Amayi omwe ali ndi PD amakonda kukhumudwa kwambiri kuposa amuna omwe ali ndi PD. Chifukwa chake amalandira mankhwala ochepetsa nkhawa nthawi zambiri.
Amuna atha kukhala ndimavuto azikhalidwe komanso nkhwidzi, monga chiopsezo chachikulu choyendayenda komanso machitidwe osayenera kapena ozunza. Amuna amatha kulandira mankhwala a antipsychotic kuti athetse vutoli.