R-CHOP Chemotherapy: Zotsatira zoyipa, Mlingo, ndi Zambiri

Zamkati

• Kodi R-CHOP imachiza chiyani?
• Kodi R-CHOP imagwira ntchito bwanji?
• Rituximab (Rituxan)
• Cyclophosphamide (Cytoxan)
• Doxorubicin hydrochloride (Adriamycin, Rubex)
• Vincristine (Oncovin, Vincasar PFS, Vincrex)
• Zamgululi
• Amapatsidwa bwanji?
• Kodi zotsatira zake zingakhale zotani?
• Kodi muyenera kudziwa chiyani musanayambe kumwa mankhwala?
• Ndi chiyani china chomwe muyenera kudziwa?

Kodi R-CHOP chemotherapy ndi chiyani?

Mankhwala a chemotherapy amatha kuchepetsa zotupa kapena kupha ma cell a khansa omwe amasokera pambuyo pochita opaleshoni kapena radiation. Ndi machiritso amachitidwe, kutanthauza kuti cholinga chake ndikupha ma cell a khansa mthupi lanu lonse.

Mankhwala onse a chemotherapy amagwira ntchito kupha ma cell a khansa, koma amachita m'njira zosiyanasiyana. Ichi ndichifukwa chake oncologists nthawi zambiri amasankha kuphatikiza mankhwala. Amatengera zisankho zawo pazinthu monga mtundu wa khansa yomwe muli nayo, momwe yafalikira, komanso thanzi lanu lonse.

R-CHOP imaphatikizapo mankhwala asanu a chemotherapy:

• rituximab (Rituxan)
• cyclophosphamide
• doxorubicin hydrochloride
• vincristine (Oncovin, Vincasar PFS)
• chibadul

Mutha kupeza R-CHOP popanda kapena mankhwala ena monga opaleshoni ndi mankhwala a radiation.

Kodi R-CHOP imachiza chiyani?

Madokotala amagwiritsa ntchito R-CHOP kuchiza non-Hodgkin lymphoma (NHL) ndi ma lymphomas ena. Lymphoma ndi khansa yomwe imayamba m'mitsempha.

R-CHOP amathanso kuchiza mitundu ina ya khansa.

Kodi R-CHOP imagwira ntchito bwanji?

Mankhwala atatu mu R-CHOP ndi cytotoxics yamphamvu, zomwe zikutanthauza kuti amapha maselo. Imodzi ndi mtundu wa immunotherapy ndipo womaliza ndi steroid, yomwe yawonetsa kuti ili ndi zotsatira za anticancer.

Rituximab (Rituxan)

Rituximab imagwiritsidwa ntchito pochiza NHL. Ndi antioclonal antibody. Imalowera puloteni yotchedwa CD20 pamwamba pamaselo oyera amwazi omwe amatchedwa "B maselo. Mankhwalawo akangolumikizana ndi ma B, chitetezo chamthupi chanu chimawaukira ndikuwapha.

Cyclophosphamide (Cytoxan)

Mankhwalawa amatha kuchiza khansa zosiyanasiyana, kuphatikizapo lymphoma ndi khansa ya m'mawere ndi m'mapapo. Cyclophosphamide imayang'ana DNA yamaselo a khansa ndikuwadziwitsa kuti asiye kugawa.

Doxorubicin hydrochloride (Adriamycin, Rubex)

Mankhwalawa ndi anthracycline omwe amatha kuchiza mitundu yambiri ya khansa, kuphatikiza khansa ya m'mawere, m'mapapo, komanso yamchiberekero. Doxorubicin amateteza maselo a khansa ya enzyme amafunika kukula ndikubala. Ndi mtundu wofiira wowala womwe watcha dzina lake "satana wofiira."

Vincristine (Oncovin, Vincasar PFS, Vincrex)

Vincristine ndi alkaloid yomwe imatha kuchiza mitundu yambiri ya khansa, kuphatikiza khansa ya m'mawere, ma lymphomas, ndi leukemia. Zimasokoneza majini kuti zisiwonekere. Mankhwalawa ndi owopsa, kutanthauza kuti amatha kuwononga minofu ndi zotengera.

Zamgululi

Mankhwalawa ndi corticosteroid yomwe imapezeka pansi pa mayina osiyanasiyana. Mosiyana ndi enawo, awa ndi mankhwala akumwa. Zimagwira ntchito ndi chitetezo cha mthupi lanu kuti muchepetse:

• kutupa
• nseru
• kusanza
• thupi lawo siligwirizana
• magulu otsika a mapiritsi, kapena thrombocytopenia
• kuchuluka kwa calcium, kapena hypercalcemia

Pamodzi, mankhwalawa amapanga malo omenyera khansa.

Amapatsidwa bwanji?

Mlingo wokhazikika umatengera kutalika ndi kulemera. Dokotala wanu adzaganiziranso zaumoyo wina uliwonse womwe muli nawo, msinkhu wanu, komanso momwe amayembekezera kuti mungalekerere mankhwalawa mukamazindikira kuchuluka kwa kuchuluka kwa mayendedwe.

Anthu nthawi zambiri amalandira mankhwalawa milungu iwiri kapena itatu iliyonse. Nthawi zambiri, madotolo amapereka mitundu isanu ndi umodzi kapena mizere isanu ndi umodzi. Chithandizo chimatenga masabata 18 kapena kupitilira apo ngati muli ndi zozungulira zina.

Musanalandire chithandizo chilichonse, mufunika kuyezetsa magazi kuti muwone kuchuluka kwa magazi ndikuwona ngati chiwindi ndi impso zanu zikugwira ntchito mokwanira. Ngati iwo sali, dokotala wanu angafunikire kuchedwetsa chithandizo chanu kapena kuchepetsa mlingo wanu.

Chithandizo cha munthu aliyense chimatha kutenga maola angapo, ndipo wothandizira zaumoyo amakupatsani mankhwalawa kudzera m'mitsempha, kutanthauza kudzera mumitsempha ya m'manja mwanu. Muthanso kudutsa pa doko lomwe dokotalayo amatha kuliyika m'chifuwa mwanu. Mungafunike kukhala mchipatala kuti mulandire chithandizo chanu, koma anthu amatha kuchipatala nthawi zambiri.

Mudzayang'anitsitsa nthawi zonse. Mukalandira chithandizo choyamba, omwe amakuthandizani pa zaumoyo adzakuyang'anirani mosamala ngati pali zizindikiro zilizonse zomwe zingayambitse matenda ena kapena matenda ena a khansa otchedwa tumor lysis syndrome.

Prednisolone ndi mankhwala akumwa omwe mumamwa kunyumba kwa masiku angapo mutalandira mankhwala ena.

Kodi zotsatira zake zingakhale zotani?

Mankhwala a chemotherapy amalimbana ndi maselo a khansa. Zitha kuwonongera maselo athanzi pochita izi. Ndicho chifukwa chake pali zovuta zambiri zomwe zingachitike. Ndizokayikitsa kuti mudzakhala nawo onse.

Chemotherapy imakhudza aliyense mosiyanasiyana. Zotsatira zoyipa zimatha kusintha mukamakhala ndi mankhwalawa, koma nthawi zambiri amakhala osakhalitsa. Gulu lanu lazachipatala lingakupatseni chidziwitso cha momwe mungachitire nawo.

Zotsatira zoyipa kwambiri ndi izi:

• kukwiya mozungulira malo olumikizira kapena olondera
• mkodzo wofiira kapena pinki masiku angapo chifukwa cha doxorubicin
• chilakolako kusintha
• kulemera kumasintha
• kudzimbidwa
• nseru
• kusanza
• kutopa
• mavuto ogona
• magazi ochepa
• kuchepa kwa magazi m'thupi
• mphuno kutuluka magazi
• mphuno yothamanga
• nkhama zotuluka magazi
• zilonda mkamwa
• Zilonda zam'kamwa
• kutayika tsitsi
• Kutaya msambo, kapena amenorrhea
• kutaya chonde
• kusamba msanga
• kudziwa khungu
• mavuto amitsempha, kapena matenda amitsempha

Zotsatira zoyipa zochepa zingaphatikizepo:

• totupa pakhungu chifukwa cha kusagwirizana
• kutentha kapena kukodza kopweteka
• kusintha kwa kukoma
• kusintha kwa zikhadabo ndi zikhadabo zazikazi
• kusintha kwa minofu ya mtima
• kutsegula m'mimba

Zotsatira zoyipa zimaphatikizapo kusintha kwa minofu yam'mapapo ndikupanga khansa yamtsogolo mtsogolo.

Kodi muyenera kudziwa chiyani musanayambe kumwa mankhwala?

Musanayambe chemotherapy, mudzakumana ndi oncologist wanu. Ino ndi nthawi yofunsa mafunso pazomwe mungayembekezere mukalandira chithandizo komanso mukalandira chithandizo. Tsatirani malangizo awa:

• Uzani dokotala wanu ngati mukumwa mapiritsi oletsa kubereka, mankhwala ena, kapena zowonjezera zakudya. Zina mwazinthuzi, ngakhale zomwe zili pakauntala, zitha kuyambitsa mavuto.
• Ngati mukuyamwitsa pakali pano, muyenera kusiya chifukwa mankhwalawa amatha kudutsa mkaka wa m'mawere kupita kwa mwana wanu.
• Uzani dokotala wanu ngati mukuganiza kuti mutha kutenga pakati. Mankhwalawa amatha kuvulaza mwana wanu ndikupangitsa kupunduka.
• Mankhwala a chemotherapy amatha kusokoneza kubereka kwanu ndikupangitsa kuti musambe msambo. Ngati mukukonzekera banja, lankhulani ndi adokotala za njira zakulera ndipo mwina mungakumane ndi katswiri wa chonde ngati pakufunika musanalandire chithandizo choyamba.
• Mankhwala a chemotherapy amakhudza chitetezo cha m'thupi lanu. Musalandire katemera uliwonse pa chemotherapy, ndipo funsani dokotala nthawi yomwe zingakhale bwino kutero.
• Zotsatira zoyipa zochokera ku chemotherapy zikuyembekezeredwa, koma zimatha kusamalidwa ndi mankhwala, zithandizo zapakhomo, ndi othandizira othandizira. Musazengereze kulankhula ndi dokotala wanu za zovuta zomwe zimayambitsa mavuto.

Ndi chiyani china chomwe muyenera kudziwa?

Pamene masabata akudutsa, mumayamba kuzolowera ndandanda ya chithandizo, koma zotsatirapo zake zimapitilira. Mutha kutopa kwambiri. Ndibwino kuti wina azikuthamangitsani kupita ku chemotherapy ndikukuthandizani munjira zina mukamalandira chithandizo.

Malangizo awa atha kukuthandizani kuti mukhale ndi chemotherapy bwino komanso kuti musapanikizike:

• Valani zovala zabwino ndipo mubweretse juzi kapena bulangeti. Anthu ena amabwera ndi mtsamiro kapena ma slippers omwe amakonda.
• Bweretsani zinthu zowerengera kapena masewera kuti mudutse nthawiyo.
• Ngati mwatopa, ziloleni kuti mugone mukamalandira chithandizo.
• Uzani namwino kapena dokotala wanu ngati muli ndi zizindikiro zosazolowereka.

Pambuyo pa chemotherapy, ndikofunikanso kuchita izi:

• Pitirizani kudya chakudya chopatsa thanzi, ngakhale mutakhala kuti mulibe njala.
• Imwani madzi ambiri ndikukhala opanda madzi.
• Muzipuma mokwanira.
• Chitani nawo masewera olimbitsa thupi nthawi zonse momwe mungathere.
• Yesetsani kuthandizidwa ndi ntchito zapakhomo.
• Pewani kukhala pafupi ndi anthu omwe ali ndi matenda opatsirana chifukwa chitetezo chanu chamthupi chimakhala chofooka.
• Khalani ocheza ndi abale anu komanso anzanu, koma khalani ndi nthawi yanokha pamene mukufunikira kutero.