Chilichonse Chimene Mumafuna Kudziwa Zokhudza SGLT2 Inhibitors

Zamkati

• Kodi mitundu yosiyanasiyana ya SGLT2 inhibitors ndi iti?
• Kodi mankhwalawa amatengedwa bwanji?
• Kodi maubwino otenga SGLT2 inhibitor ndi ati?
• Kodi ndi zoopsa zotani zomwe zingachitike ndikumwa mankhwalawa?
• Kodi ndizotheka kuphatikiza mankhwala amtundu uwu ndi mankhwala ena?
• Kutenga

Chidule

SGLT2 inhibitors ndi gulu la mankhwala omwe amagwiritsidwa ntchito pochizira matenda amtundu wa 2. Amatchedwanso sodium-glucose transport protein 2 inhibitors kapena gliflozins.

SGLT2 inhibitors imalepheretsa kubwezeretsanso shuga m'magazi omwe amasankhidwa kudzera mu impso zanu, motero kumathandizira kutulutsa kwa glucose mkodzo. Izi zimathandiza kuchepetsa kuchuluka kwa shuga m'magazi anu.

Pemphani kuti mudziwe zambiri zamitundu yosiyanasiyana ya SGLT2 inhibitors, komanso maubwino ndi zoopsa zomwe zingachitike pakuwonjezera mtundu uwu wa mankhwala kuchipatala.

Kodi mitundu yosiyanasiyana ya SGLT2 inhibitors ndi iti?

Mpaka pano, US Food and Drug Administration (FDA) yavomereza mitundu inayi ya SGLT2 inhibitors yothandizira matenda amtundu wa 2:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• ertugliflozin (Steglatro)

Mitundu ina ya SGLT2 inhibitors ikupangidwa ndikuyesedwa m'mayesero azachipatala.

Kodi mankhwalawa amatengedwa bwanji?

SGLT2 inhibitors ndi mankhwala akumwa. Amapezeka pamapiritsi.

Ngati dokotala wanu akuwonjezera choletsa SGLT2 ku dongosolo lanu la mankhwala, angakulimbikitseni kuti muzimwa kamodzi kapena kawiri patsiku.

Nthawi zina, dokotala akhoza kukupatsani mankhwala oletsa SGLT2 pamodzi ndi mankhwala ena a shuga. Mwachitsanzo, gulu la mankhwalawa limatha kuphatikizidwa ndi metformin.

Kuphatikiza kwa mankhwala ashuga kungakuthandizeni kuti shuga yanu yamagazi isamayende bwino. Ndikofunika kumwa mlingo woyenera wa mankhwala aliwonse kuti muchepetse kuchuluka kwa shuga m'magazi anu kuti asatsike kwambiri.

Kodi maubwino otenga SGLT2 inhibitor ndi ati?

Mukamamwa nokha kapena ndi mankhwala ena ashuga, SGLT2 inhibitors itha kukuthandizani kuti muchepetse shuga. Izi zimachepetsa mwayi wanu wopeza zovuta kuchokera ku mtundu wachiwiri wa shuga.

Malinga ndi kafukufuku wa 2018 wofalitsidwa mu nyuzipepala ya Diabetes Care, asayansi akuti SGLT2 inhibitors itha kulimbikitsanso kuchepa kwa thupi komanso kusintha pang'ono pagazi lanu komanso m'magazi a cholesterol.

Ndemanga ya 2019 idapeza kuti SGLT2 inhibitors adalumikizidwa ndi chiopsezo chochepa cha sitiroko, matenda amtima, komanso kufa ndi matenda amtima mwa anthu omwe ali ndi matenda a shuga amtundu wa 2 komanso mitsempha yolimba.

Kuwunikanso komweku kunapeza kuti SGLT2 inhibitors itha kuchepetsa kukula kwa matenda a impso.

Kumbukirani, zabwino zomwe SGLT2 inhibitors imasiyana zimasiyana malinga ndi mbiri ya zamankhwala.

Kuti mudziwe zambiri za mtundu uwu wa mankhwala, komanso ngati ndi oyenera dongosolo lanu la mankhwala, lankhulani ndi dokotala wanu.

Kodi ndi zoopsa zotani zomwe zingachitike ndikumwa mankhwalawa?

SGLT2 inhibitors amadziwika kuti ndi otetezeka, koma nthawi zina, amatha kuyambitsa zovuta.

Mwachitsanzo, kumwa mtundu uwu wa mankhwala kumatha kubweretsa chiopsezo chotenga:

• matenda opatsirana mumkodzo
• matenda opatsirana pogonana osagonana, monga matenda a yisiti
• ketoacidosis ya shuga, yomwe imapangitsa magazi anu kukhala acidic
• hypoglycemia, kapena shuga wotsika magazi

Nthawi zambiri, matenda opatsirana pogonana akhala ali mwa anthu omwe amatenga SGLT2 inhibitors. Matenda amtunduwu amadziwika kuti necrotizing fasciitis kapena chotupa cha Fournier.

Kafukufuku wina akuwonetsanso kuti canagliflozin itha kuwonjezera chiopsezo cha mafupa. Zotsatira zoyipazi sizinagwirizane ndi zoletsa zina za SGLT2.

Dokotala wanu akhoza kukudziwitsani zambiri za kuopsa kotenga SGLT2 inhibitors. Angakuthandizeninso kudziwa momwe mungazindikirire ndikuwongolera zovuta zilizonse zomwe zingachitike.

Ngati mukuganiza kuti mwina mukukumana ndi zovuta zamankhwala, funsani dokotala nthawi yomweyo.

Kodi ndizotheka kuphatikiza mankhwala amtundu uwu ndi mankhwala ena?

Mukamawonjezera mankhwala atsopano ku mapulani anu, ndikofunikira kuganizira momwe zingagwirizane ndi mankhwala omwe mumamwa kale.

Ngati mumamwa mankhwala ena ashuga kuti muchepetse shuga, kuwonjezera SGLT2 inhibitor kumawonjezera chiopsezo chokhala ndi shuga wotsika magazi.

Kuphatikiza apo, ngati mukumwa mitundu ina ya okodzetsa, SGLT2 inhibitors imatha kukulitsa mphamvu ya mankhwala okodzetsa, kukupangitsani kukodza pafupipafupi. Izi zitha kukulitsa chiopsezo chotaya madzi m'thupi komanso kuthamanga magazi.

Musanayambe kumwa mankhwala atsopano, funsani dokotala ngati angagwirizane ndi chilichonse chomwe mungapeze.

Nthawi zina, dokotala wanu amatha kusintha mankhwala omwe mwalandira kuti muchepetse kuyanjana ndi mankhwala osokoneza bongo.

Kutenga

SGLT2 inhibitors adapangidwa kuti azithandizira kusamalira shuga wamagazi mwa anthu omwe ali ndi matenda amtundu wa 2.

Kuphatikiza pa kuchepetsa kuchuluka kwa shuga m'magazi, mankhwala amtunduwu apezeka kuti ali ndi maubwino amtima ndi impso. Ngakhale kuti nthawi zambiri amadziwika kuti ndi otetezeka, ma SGLT2 inhibitors nthawi zina amayambitsa zoyipa kapena mayendedwe olakwika ndi mankhwala ena.

Dokotala wanu angakuuzeni zambiri za zabwino zomwe zingachitike komanso zoopsa zowonjezerapo mankhwala amtunduwu kuchipatala.