Simvastatin vs. Atorvastatin: Zomwe Muyenera Kudziwa

Zamkati

• Zotsatira zoyipa
• Kupweteka kwa minofu
• Kutopa
• Kukhumudwa m'mimba ndi kutsegula m'mimba
• Chiwindi ndi matenda a impso
• Sitiroko
• Shuga wamagazi komanso matenda ashuga
• Kuyanjana
• Kupezeka ndi mtengo
• Chotengera

Za ma statins

Simvastatin (Zocor) ndi atorvastatin (Lipitor) ndi mitundu iwiri yazikhalidwe zomwe dokotala angakupatseni. Ma Statins nthawi zambiri amaperekedwa kuti athandize kuchepetsa cholesterol yanu. Malinga ndi American College of Cardiology, ma statins amatha kukuthandizani ngati:

• khalani ndi cholesterol yambiri m'mitsempha mwanu
• muli ndi LDL, yomwe imadziwikanso kuti cholesterol yoyipa, yayikulu kuposa mamiligalamu 190 pa deciliter (mg / dL)
• ali ndi matenda ashuga, ali pakati pa 40 ndi 75 wazaka, ndipo ali ndi mulingo wa LDL pakati pa 70 ndi 189 mg / dL, ngakhale osakhala ndi cholesterol m'mitsempha mwanu
• muli ndi LDL pakati pa 70 mg / dL ndi 189 mg / dL, ali ndi zaka zapakati pa 40 ndi 75, ndipo ali ndi chiwopsezo chotsika 7.5 peresenti kuti cholesterol ingamange m'mitsempha mwanu

Mankhwalawa ndi ofanana, ndimasiyana pang'ono. Onani momwe amadzikundikira.

Zotsatira zoyipa

Onse simvastatin ndi atorvastatin amatha kuyambitsa zovuta zosiyanasiyana. Zotsatira zina zoyipa zimatha kuchitika ndi simvastatin, ndipo zina zimakhala ndi atorvastatin.

Kupweteka kwa minofu

Ma statin onse amatha kupweteketsa minofu, koma izi ndizotheka kugwiritsa ntchito simvastatin. Kupweteka kwa minofu kumatha kukula pang'onopang'ono. Ikhoza kumverera ngati minofu yokoka kapena kutopa kuchokera ku masewera olimbitsa thupi. Itanani dokotala wanu za ululu uliwonse watsopano mukakhala ndi statin, makamaka simvastatin. Kupweteka kwa minofu kungakhale chizindikiro cha kukhala ndi mavuto a impso kapena kuwonongeka.

Kutopa

Zotsatira zoyipa zomwe zingachitike ndi mankhwala aliwonse ndikutopa. Kafukufuku woperekedwa ndi (NIH) anayerekezera kutopa kwa odwala omwe amamwa pang'ono simvastatin ndi mankhwala ena otchedwa pravastatin. Amayi, makamaka, ali pachiwopsezo chachikulu chotopa kuchokera kuma statins, ngakhale ali ochokera ku simvastatin.

Kukhumudwa m'mimba ndi kutsegula m'mimba

Mankhwala onsewa amatha kukhumudwitsa m'mimba komanso kutsegula m'mimba. Zotsatirazi nthawi zambiri zimatha pakatha milungu ingapo.

Chiwindi ndi matenda a impso

Ngati muli ndi matenda a impso, atorvastatin ikhoza kukhala chisankho chabwino kwa inu chifukwa palibe chifukwa chosinthira mlingo. Kumbali inayi, simvastatin imatha kukhudza impso zanu zikagwiritsidwa ntchito kwambiri (80 mg patsiku). Ikhoza kuchepetsa impso zanu. Simvastatin imamangidwanso m'dongosolo lanu pakapita nthawi. Izi zikutanthauza kuti ngati mutamwa kwa nthawi yayitali, kuchuluka kwa mankhwala omwe ali m'dongosolo lanu kumatha kuwonjezera. Dokotala wanu ayenera kusintha mlingo wanu.

Komabe, kutengera zotsatira za kafukufuku wa 2014 wa, sipangakhale chiwopsezo chowonjezeka chovulala kwa impso pakati pa simvastatin wa mlingo waukulu ndi atorvastatin. Kuphatikiza apo, mankhwala a simvastatin okwera mpaka 80 mg patsiku salinso wamba.

Anthu ochepa omwe amatenga ma statins amakhala ndi matenda a chiwindi. Ngati mwadetsa mkodzo kapena kupweteka mbali yanu mukamamwa mankhwalawa, itanani dokotala wanu mwachangu.

Sitiroko

Mlingo waukulu wa atorvastatin (80 mg patsiku) umalumikizidwa ndi chiopsezo chachikulu cha kukha magazi ngati mwadwala matenda a ischemic kapena a ischemic attack (TIA, omwe nthawi zina amatchedwa mini stroke), m'miyezi isanu ndi umodzi yapitayi.

Shuga wamagazi komanso matenda ashuga

Simvastatin onse ndi atorvastatin amatha kuwonjezera shuga m'magazi komanso chiopsezo chokhala ndi matenda ashuga. Ma statin onse amatha kukulitsa mulingo wa hemoglobin A1C, womwe ndi mulingo wa shuga wanthawi yayitali wamagazi.

Kuyanjana

Ngakhale mphesa si mankhwala, madokotala amalangiza kuti mupewe kumwa zipatso zambiri zam'madzi kapena zipatso za manyumwa ngati mutenga ma statins. Ndi chifukwa chakuti mankhwala omwe ali mumtengowo amatha kusokoneza kuwonongeka kwa ma statin ena mthupi lanu. Izi zitha kukulitsa kuchuluka kwa ma statins m'magazi anu ndikuwonjezera mwayi wanu wamavuto.

Simvastatin onse ndi atorvastatin amatha kulumikizana ndi mankhwala ena. Mutha kupeza mndandanda wazomwe amachita muzolemba za Healthline pa simvastatin ndi atorvastatin. Makamaka, atorvastatin imatha kulumikizana ndi mapiritsi oletsa kubereka.

Kupezeka ndi mtengo

Simvastatin onse ndi atorvastatin ndi mapiritsi okutidwa ndi kanema omwe mumamwa, nthawi zambiri kamodzi patsiku. Simvastatin amatchedwa Zocor, pomwe Lipitor ndiye dzina la atorvastatin. Iliyonse imapezeka ngati mankhwala achibadwa, komanso. Mutha kugula mankhwala m'masitolo ambiri ndi mankhwala ochokera kwa dokotala.

Mankhwalawa amapezeka motere:

• Simvastatin: 5 mg, 10 mg, 20 mg, 40 mg, ndi 80 mg
• Atorvastatin: 10 mg, 20 mg, 40 mg, ndi 80 mg

Mtengo wa generic simvastatin ndi atorvastatin onse ndi otsika kwambiri, ndipo generic simvastatin imakhala yotsika mtengo pang'ono. Amabwera pafupifupi $ 10-15 pamwezi. Atorvastatin nthawi zambiri amakhala $ 25-40 pamwezi.

Mankhwala odziwika ndi okwera mtengo kwambiri kuposa ma generic awo. Zocor, mtundu wa simvastatin, ili pafupifupi $ 200-250 pamwezi. Lipitor, mtundu wa atorvastatin, nthawi zambiri imakhala $ 150-200 pamwezi.

Chifukwa chake ngati mukugula generic, simvastatin ndi wotsika mtengo. Koma zikafika pamitundu yamaina, atorvastatin ndiotsika mtengo.

Chotengera

Dokotala wanu adzawona zambiri povomereza chithandizo ndi statin monga simvastatin ndi atorvastatin. Nthawi zambiri, kusankha mankhwala oyenera sikungafanane ndi mankhwalawo ndikufanana ndi zomwe zingachitike ndi zotsatirapo za mankhwalawa ndi mbiri yanu yazachipatala ndi mankhwala ena omwe mumamwa.

Ngati mukumwa simvastatin kapena atorvastatin, funsani dokotala mafunso otsatirawa:

• Chifukwa chiyani ndikumwa mankhwalawa?
• Kodi mankhwalawa amandigwira ntchito bwanji?

Ngati mukukumana ndi zovuta monga kupweteka kwa minofu kapena mkodzo wamdima, lankhulani ndi dokotala nthawi yomweyo. Komabe, musaleke kutenga statin yanu osalankhula ndi dokotala wanu. Statins amangogwira ntchito ngati atengedwa tsiku lililonse.