Chithandizo ndi Chithandizo cha ADPKD

Zamkati

• Mankhwala
• Kukula kwa impso
• Kuthamanga kwa magazi
• Matenda
• Ululu
• Zakudya ndi madzi
• Opaleshoni yochiza zovuta
• Dialysis kapena impso kumuika
• Mankhwala othandizira
• Kutenga

Matenda a impso a Autosomal opatsirana kwambiri a polycystic (ADPKD) ndi omwe amapezeka kwambiri pamatenda a impso a polycystic (PKD).

Zitha kubweretsa zovuta zosiyanasiyana, monga:

• ululu
• kuthamanga kwa magazi
• impso kulephera

Palibe mankhwala a ADPKD panobe. Dokotala wanu akhoza kukupatsani mankhwala, kusintha kwa moyo wanu, ndi zina zomwe mungachite kuti muchepetse zizindikilo ndikupewa zovuta.

Werengani kuti mudziwe zambiri zamankhwala ndi chithandizo cha APDKD.

Mankhwala

Dokotala wanu akhoza kukupatsani mankhwala angapo kutengera zomwe mumakumana nazo kapena zovuta za ADPKD.

Kukula kwa impso

Mu 2018, Food and Drug Administration (FDA) idavomereza mankhwala tolvaptan (Jynarque) kuti athetse ADPKD.

Mankhwalawa amathandiza kuchepetsa kukula kwa zotupa zomwe zimachitika ndi ADPKD. Izi zimathandiza kuchepetsa kuwonongeka kwa impso ndikuchepetsa chiopsezo cha impso.

Pali chiopsezo chovulala pachiwindi kapena kugwiritsa ntchito mankhwala mukamamwa tolvaptan. Gwiritsani ntchito ndi dokotala yemwe amaganizira zaumoyo wa impso kuti zinthu zikuyendereni bwino.

Tolvaptan itha kugwiritsidwa ntchito kwa akulu omwe ali ndi:

• Gawo lachiwiri kapena lachitatu la matenda a impso koyambirira koyambira
• umboni wakukula kwa matenda a impso

Zotsatira zoyipa za tolvaptan (Jynarque) ndizo:

• kusawona bwino
• kuvuta kupuma kapena kupuma movutikira
• pakamwa pouma kapena khungu louma
• kukodza pafupipafupi
• fungo lokhala ngati zipatso
• kuchuluka kwa njala kapena ludzu
• kuchuluka kukodza kapena kuchuluka kwa mkodzo wosungunuka
• nseru, kusanza, kapena kupweteka m'mimba
• thukuta
• kuonda kosadziwika
• kufooka kapena kutopa kwachilendo

Kuthamanga kwa magazi

Kuthamanga kwa magazi kumathandizira kukulira kwa matendawa.

Dokotala wanu angakulimbikitseni kusintha kwa moyo wanu komanso mankhwala omwe angakhale ngati angiotensin-converting enzyme (ACE) inhibitors kapena angiotensin II receptor blockers (ARBs) kuti akuthandizeni kuthana ndi kuthamanga kwa magazi.

Matenda

Matenda a m'mitsempha (UTIs), monga chikhodzodzo kapena matenda a impso, okhudzana ndi ADPKD amatha kuchiritsidwa ndi maantibayotiki. Chithandizo chotalikirapo chitha kufunikira ngati matendawa ndi ovuta kuposa matenda a chikhodzodzo.

Ululu

Mankhwala ochiritsira monga acetaminophen angathandize kuthetsa ululu uliwonse wokhudzana ndi:

• zotupa mu impso
• matenda
• impso miyala

Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs), monga ibuprofen, samalimbikitsidwa chifukwa chokhoza kusokoneza magazi ndi ntchito ya impso.

Mankhwala oletsa kulanda amathanso kugwiritsidwa ntchito pothandiza kuchepetsa ululu womwe umayambitsidwa ndi mitsempha. Izi zikuphatikizapo pregabalin (Lyrica) ndi gabapentin (Neurontin).

Ngati ululu sungathe kuwongoleredwa ndi njirazi, dokotala wanu angaganize zopereka mankhwala ena opweteka monga ma opioid. Opioids ali ndi zovuta zoyipa komanso kuthekera kodalira, chifukwa chake gwirani ntchito ndi dokotala kuti mupeze mlingo wotsikitsitsa wofunikira kuti muthane ndi ululu wanu.

Nthawi zonse lankhulani ndi dokotala musanamwe mankhwala amtundu wina, kuphatikiza ocheperako. Mankhwala ena ochepetsa ululu ndi mankhwala ena atha kuvulaza impso zanu.

Zakudya ndi madzi

Zomwe mumadya zitha kukhala ndi thanzi labwino impso zanu, komanso kuthamanga kwa magazi. Kukhala ndi hydrated yabwino kumathandizanso, ndipo kungathandizenso kupititsa miyala ya impso komanso kupewa ma UTIs.

Pofuna kukuthandizani kukhala ndi zizolowezi zodyera zomwe zimakwaniritsa zosowa zanu zaumoyo, adokotala angakutumizireni kwa katswiri wazakudya. Amatha kukuthandizani kuti muphunzire zakudya zomwe muyenera kudya ndi zomwe muyenera kupewa kapena kupewa.

Mwachitsanzo, akhoza kukulimbikitsani kuti:

• kuchepetsa mchere, kapena sodium, mu zakudya zanu momwe mungathere kuti muchepetse kuthamanga kwa magazi
• idyani magawo ang'onoang'ono a mapuloteni apamwamba kuti muteteze impso zanu
• kuchepetsa kumwa mafuta osinthasintha komanso okhutira momwe mungathere wathanzi
• pewani kudya potaziyamu kapena phosphorous kwambiri
• kuchepetsa kumwa mowa

Ndikofunikanso kumwa madzi okwanira kuti akhalebe ndi madzi okwanira. Ofufuzawa akuphunzira momwe hydration imakhudzira vutoli.

Opaleshoni yochiza zovuta

Ngati mukukhala ndi zovuta za ADPKD, dokotala wanu angakulimbikitseni kuchitidwa opaleshoni ngati gawo la njira yanu yothandizira.

Mwachitsanzo, atha kukupatsani opaleshoni ngati mutakula:

• zotupa mu impso zanu kapena ziwalo zina zomwe zimapweteka kwambiri zomwe sizingatheke ndi mankhwala
• diverticulitis yovuta kapena yabwinobwino, yomwe ingakhudze khoma la colon yanu
• aneurysm yaubongo, yomwe imatha kukhudza mitsempha yamagazi muubongo wanu

Mitundu ya zosankha za ADPKD ndi monga:

• Ngalande ya opaleshoni. Matenda opatsirana omwe samayankha mankhwala a maantibayotiki amatha kutulutsa madzi ndi singano.
• Opaleshoni yotseguka kapena ya fiberoptic. Izi zimatha kutulutsa makoma akunja a zotupa kuti athetse ululu.
• Kuchotsa impso (nephrectomy). Kuchotsa gawo kapena impso zonse kungakhale njira yowopsya kwambiri kwa ziphuphu zomwe sizingasunthike kapena kuchotsedwa kudzera njira zina.
• Kuchotsa pang'ono chiwindi (hepatectomy) kapena kumuika. Pakukulitsa chiwindi kapena zovuta zina zokhudzana ndi chiwindi, kuchotsedwa pang'ono kwa chiwindi kapena kumuwonjezera chiwindi kungalimbikitsidwe.

Opaleshoni ingathandize kuthana ndi zovuta zina za vutoli. Komabe, sizingachedwetse chitukuko chonse cha ADPKD.

Dialysis kapena impso kumuika

Impso zanu zimagwira ntchito yofunikira pochepetsa zonyansa ndi madzi owonjezera m'magazi anu.

Mukayamba kulephera kwa impso, mufunika dialysis kapena kumuika impso kuti mupulumuke.

Pali mitundu iwiri yayikulu ya dialysis:

• kusanthula magazi
• peritoneal dialysis

Mu hemodialysis, makina akunja amagwiritsidwa ntchito kusefa magazi anu kunja kwa thupi lanu. Mu peritoneal dialysis, m'mimba mwanu mumadzaza ndi dialysate (dialyzing fluid) kusefa magazi anu mkati mwa thupi lanu.

Mukalandira impso, dokotalayo amaika impso kuchokera kwa munthu wina kulowa m'thupi lanu. Zitha kutenga zaka kuti mupeze machesi abwino a impso opereka.

Mankhwala othandizira

Mankhwala ena othandizira angakuthandizeni kuchepetsa kupsinjika kapena kupweteka kwanu. Izi zitha kuthandiza kuchepetsa kuthamanga kwa magazi ndikulimbikitsa moyo wabwino ndi ADPKD.

Zochita zomwe zitha kuthandizira kupsinjika kapena kupweteka zimaphatikizapo:

• kutikita
• kutema mphini
• kusinkhasinkha
• yoga
• tai chi

Kukhala ndi moyo wathanzi ndikofunikanso pakuthana ndi kuthamanga kwa magazi ndikulimbikitsa thanzi labwino la impso. Mwachitsanzo, yesani:

• kugona mokwanira
• kuchita masewera olimbitsa thupi nthawi zonse
• pewani kusuta

Nthawi zonse lankhulani ndi dokotala musanayesere mankhwala othandizira kapena musinthe kwambiri moyo wanu. Amatha kukuthandizani kudziwa ngati mankhwalawa kapena kusintha kwake kuli bwino kwa inu.

Musamamwe mankhwala azitsamba kapena mavitamini osalankhula ndi dokotala kuti mudziwe ngati ali otetezeka. Mankhwala ambiri azitsamba komanso mavitamini owonjezera amawononga impso zanu.

Kutenga

Ngakhale ADPKD ilibe mankhwala, dokotala akhoza kukulangizani zamankhwala, chithandizo chamankhwala, njira zamoyo, ndipo nthawi zina, opaleshoni kuti muthane ndi vutoli.

Adziwitseni dokotala ngati mukukula ndi zachilendo kapena zosintha zina paumoyo wanu. Angakulimbikitseni kusintha kwa dongosolo lanu la mankhwala.

Lankhulani ndi dokotala wanu kuti mudziwe zambiri zamaubwino ake, zoopsa zake, ndi mtengo wake wosankha mankhwala osiyanasiyana.