Mapuloteni alveolar proteinosis

Pulmonary alveolar proteinosis (PAP) ndi matenda osowa omwe mtundu wamapuloteni umamangirira m'matumba am'mapapo (alveoli) m'mapapu, ndikupangitsa kupuma kukhala kovuta. Njira zamapapu zokhudzana ndi mapapu.

Nthawi zina, chifukwa cha PAP sichidziwika. Kwa ena, zimachitika ndi matenda am'mapapo kapena vuto la chitetezo chamthupi. Zitha kuchitika ndi khansa ya m'magazi, komanso mutakumana ndi zinthu zambiri zachilengedwe, monga silika kapena fumbi la aluminium.

Anthu azaka zapakati pa 30 ndi 50 amakhudzidwa nthawi zambiri. PAP imawonekera mwa amuna nthawi zambiri kuposa azimayi. Mawonekedwe amtunduwu amapezeka pakubadwa (kobadwa nako).

Zizindikiro za PAP zitha kuphatikizira izi:

• Kupuma pang'ono
• Tsokomola
• Kutopa
• Malungo, ngati pali matenda am'mapapo
• Khungu Bluish (cyanosis) woopsa milandu
• Kuchepetsa thupi

Nthawi zina, palibe zizindikiro.

Wothandizira zaumoyo amamvetsera m'mapapu ndi stethoscope ndipo amatha kumva maphokoso m'mapapu. Nthawi zambiri, kuyezetsa thupi kumakhala kwachilendo.

Mayesero otsatirawa akhoza kuchitika:

• Bronchoscopy yokhala ndi mchere wosamba m'mapapu (kutsuka)
• X-ray pachifuwa
• Kujambula kwa CT pachifuwa
• Kuyesa kwa mapapo
• Tsegulani biopsy yamapapu (biopsy ya opaleshoni)

Kuchiza kumaphatikizapo kutsuka mapuloteni kuchokera m'mapapo (kupukutira m'mapapo) nthawi ndi nthawi. Anthu ena angafunike kumuika m'mapapo. Kupewera fumbi lomwe lingayambitse vutoli ndikulimbikitsidwanso.

Mankhwala ena omwe angayesedwe ndi mankhwala osokoneza bongo otchedwa granulocyte-macrophage colony stimulating factor (GM-CSF), omwe akusowa mwa anthu ena omwe ali ndi alveolar proteinosis.

Izi zitha kupereka zambiri pa PAP:

• National Organisation for Rare Disways - rarediseases.org/rare-diseases/pulmonary-alveolar-proteinosis
• PAP Foundation - www.papfoundation.org

Anthu ena omwe ali ndi PAP amapita kukhululukidwa. Ena ali ndi kuchepa kwa matenda am'mapapu (kulephera kupuma) komwe kumakulirakulira, ndipo angafunikire kumuika m'mapapo.

Itanani omwe akukuthandizani ngati mukukhala ndi vuto lakupuma. Kupuma pang'ono komwe kumakulirakulira pakapita nthawi kumatha kuwonetsa kuti matenda anu akukula mwadzidzidzi.

PAP; Alveolar proteinosis; M'mapapo mwanga alveolar phospholipoproteinosis; Alveolar lipoproteinosis phospholipidosis

• Matenda am'mapapo - akulu - amatulutsa

• Dongosolo kupuma

Mlembi SM. Matenda odzaza minyewa. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 85.

Trapnell BC, Luisetti M. Pulmonary alveolar proteinosis matenda. Mu: Broaddus VC, Mason RJ, Ernst JD, et al, olemba. Murray ndi Nadel's Bookbook of Respiratory Medicine. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier Saunders; 2016: chap 70.