Kodi mungakhale ndi testosterone yotsika?
Testosterone ndi hormone yopangidwa ndi machende. Ndikofunikira pagulu lachiwerewere la mamuna komanso mawonekedwe akuthupi.
Matenda ena, mankhwala, kapena kuvulala kumatha kubweretsa testosterone (low-T). Mulingo wa testosterone nawonso umatsika mwachilengedwe ndi msinkhu. Testosterone yotsika imatha kukhudza kuyendetsa kugonana, kusinthasintha, komanso kusintha kwa minofu ndi mafuta.
Kuchiza ndi mankhwala a testosterone kungathandize kuchepetsa zizindikilo.
Testosterone imamupangitsa munthu kuwoneka ndikumverera ngati mwamuna. Mwa munthu, hormone iyi imathandiza:
- Sungani mafupa ndi minofu mwamphamvu
- Dziwani kukula kwa tsitsi ndi komwe mafuta ali mthupi
- Pangani umuna
- Sungani zoyendetsa zogonana ndi zosokoneza
- Pangani maselo ofiira
- Limbikitsani mphamvu ndi malingaliro
Kuyambira zaka 30 mpaka 40, kuchuluka kwa testosterone kumatha kuyamba kuchepa pang'ono. Izi zimachitika mwachilengedwe.
Zina mwazifukwa za testosterone yotsika ndi izi:
- Zotsatira zamankhwala, monga chemotherapy
- Kuvulala kwamatenda kapena khansa
- Mavuto ndi zopangitsa mu ubongo (hypothalamus ndi pituitary) zomwe zimayang'anira kupanga mahomoni
- Ntchito yotsika ya chithokomiro
- Mafuta ochuluka kwambiri amthupi (kunenepa kwambiri)
- Matenda ena, matenda osachiritsika, chithandizo chamankhwala, kapena matenda
Amuna ena omwe ali ndi testosterone otsika alibe zisonyezo. Ena atha kukhala:
- Kuyendetsa kotsika
- Mavuto okhala ndi erection
- Kuchuluka kwa umuna
- Matenda ogona monga kusowa tulo
- Kuchepetsa kukula kwa minofu ndi nyonga
- Kutaya mafupa
- Wonjezerani mafuta amthupi
- Matenda okhumudwa
- Kuvuta kulingalira
Zizindikiro zina zitha kukhala gawo lakukalamba. Mwachitsanzo, si zachilendo kuti munthu asamakonde kugonana akamakula. Koma, si zachilendo kukhala opanda chidwi ndi zogonana.
Zizindikiro zimayambanso chifukwa cha zinthu zina, monga kuthamanga kwa magazi kapena matenda ashuga. Ngati zina mwazizindikirozi zikukuvutitsani, kambiranani ndi omwe akukuthandizani.
Wothandizira anu atha kukayezetsa magazi kuti muwone kuchuluka kwa testosterone. Muyang'ananso zina mwazomwe zimayambitsa matenda anu. Izi zimaphatikizapo zovuta zamankhwala, mavuto a chithokomiro, kapena kukhumudwa.
Ngati muli ndi testosterone wochepa, chithandizo cha mahomoni chitha kuthandiza. Mankhwala omwe amagwiritsidwa ntchito ndi testosterone yopangidwa ndi anthu. Mankhwalawa amatchedwa testosterone replacement therapy, kapena TRT. TRT itha kuperekedwa ngati mapiritsi, gel, chigamba, jakisoni, kapena kuyika.
TRT itha kuthetsa kapena kusintha zizindikiritso mwa amuna ena. Zingathandize kuti mafupa ndi minofu ikhale yolimba. TRT ikuwoneka ngati yothandiza kwambiri mwa anyamata omwe ali ndi ma testosterone otsika kwambiri. TRT itha kuthandizanso amuna okalamba.
TRT ili ndi zoopsa. Izi zingaphatikizepo:
- Kusabereka
- Kukulitsa prostate kumabweretsa zovuta kukodza
- Kuundana kwamagazi
- Kukulitsa mtima kulephera
- Mavuto ogona
- Mavuto a cholesterol
Pakadali pano, sizikudziwika ngati TRT imawonjezera chiopsezo cha matenda a mtima, sitiroko, kapena khansa ya prostate.
Lankhulani ndi omwe amakupatsani ngati TRT ikuyenererani. Ngati simukuwona kusintha kulikonse mukalandira chithandizo kwa miyezi itatu, ndizochepa kuti chithandizo cha TRT chikuthandizireni.
Ngati mungaganize zoyambira TRT, onetsetsani kuti mwawona omwe amakupatsani kuti akapimidwe pafupipafupi.
Itanani omwe akukuthandizani ngati:
- Muli ndi zizindikiro za testosterone yotsika
- Muli ndi mafunso kapena nkhawa zamankhwala
Kusamba kwa amuna; Andropause; Kulephera kwa testosterone; Otsika-T; Kuperewera kwa Androgen wamwamuna wokalamba; Hypogonadism yochedwa mochedwa
Allan CA, McLachlin RI. Matenda a Androgen akusowa. Mu: Jameson JL, De Groot LJ, de Kretser DM, et al, olemba. Endocrinology: Akuluakulu ndi Ana. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier Saunders; 2016: chap 139.
Morgentaler A, Zitzmann M, Traish AM, ndi al. Malingaliro oyambira okhudzana ndi kusowa kwa testosterone ndi chithandizo: malingaliro apadziko lonse lapansi ogwirizana. Chipatala cha Mayo. 2016; 91 (7): 881-896. PMID: 27313122 www.ncbi.nlm.nih.gov/pubmed/27313122. (Adasankhidwa)
Tsamba la U.S. Food and Drug Administration. Kuyankhulana kwachitetezo cha mankhwala a FDA: FDA imachenjeza za kugwiritsa ntchito mankhwala a testosterone a testosterone chifukwa cha ukalamba; Pamafunika kusintha kwa zilembo kuti zidziwitse za chiwopsezo chowonjezeka cha matenda amtima ndi sitiroko ndikugwiritsa ntchito. www.fda.gov/drugs/drugsafety/ucm436259.htm. Idasinthidwa pa February 26, 2018. Idapezeka pa Meyi 20, 2019.
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