Makina owerengera a Gleason

Khansa ya Prostate imapezeka pambuyo poti biopsy. Mtundu umodzi kapena zingapo zamatenda zimatengedwa kuchokera ku prostate ndikuyesedwa pansi pa microscope.

Dongosolo la Gleason grading limatanthawuza momwe ma cell anu a khansa ya Prostate amawonekera komanso momwe khansa imafalikira komanso kufalikira. Kalasi yotsika ya Gleason imatanthauza kuti khansara ikukula pang'onopang'ono osati mwamphamvu.

Njira yoyamba yodziwira kalasi ya Gleason ndiyo kudziwa kuchuluka kwa Gleason.

1. Poyang'ana maselo omwe ali pansi pa microscope, adotolo amapereka nambala (kapena kalasi) kumaselo a khansa ya prostate pakati pa 1 ndi 5.
2. Kalasi iyi imadalira momwe maselo amawonekera modabwitsa. Gawo 1 limatanthauza kuti maselo amawoneka ngati maselo abwinobwino a prostate. Gawo 5 limatanthauza kuti maselo amawoneka osiyana kwambiri ndi maselo abwinobwino a prostate.
3. Khansa zambiri za prostate zimakhala ndimaselo osiyanasiyana. Chifukwa chake magiredi ofala kwambiri amagwiritsidwa ntchito.
4. Chiwerengero cha Gleason chatsimikizika powonjezera magawo awiri omwe amapezeka kwambiri. Mwachitsanzo, magulu ofala kwambiri amtundu wa minofu amatha kukhala magawo atatu, otsatiridwa ndi magulu 4. Malingaliro a Gleason achitsanzo ichi ndi 7.

Manambala apamwamba akuwonetsa khansa yomwe ikukula mwachangu yomwe imafalikira.

Pakadali pano omaliza kwambiri omwe amatumizidwa ndi chotupa ndi giredi 3. Magiredi pansipa 3 amawonetsa zachilendo pafupi ndi maselo abwinobwino. Khansa yambiri imakhala ndi mphotho ya Gleason (kuchuluka kwa magiredi awiri omwe amapezeka kwambiri) pakati pa 6 (Gleason ambiri a 3 + 3) ndi 7 (Gleason ambiri a 3 + 4 kapena 4 + 3).

Nthawi zina, zimakhala zovuta kuneneratu momwe anthu adzachitire bwino kutengera zolemba zawo zokha za Gleason.

• Mwachitsanzo, chotupa chanu chimatha kupatsidwa mphotho ya Gleason ya 7 ngati magiredi awiri omwe anali odziwika kwambiri anali 3 ndi 4. Omwe 7 atha kubwera chifukwa chowonjezera 3 + 4 kapena powonjezerapo 4 + 3.
• Zonsezi, wina yemwe ali ndi chiwerengero cha Gleason cha 7 chomwe chimabwera chifukwa chowonjezera 3 + 4 amamverera kuti ali ndi khansara yocheperako kuposa munthu yemwe ali ndi mphotho ya Gleason ya 7 yomwe imabwera chifukwa chowonjezera 4 + 3. Izi ndichifukwa choti munthu yemwe ali ndi 4 + 3 = 7 kalasi ili ndi maselo 4 owerengeka kuposa magulu atatu. Maselo a Gulu la 4 ndi achilendo ndipo amatha kufalikira kuposa ma cell 3.

Gulu Latsopano la Gulu la 5 lapangidwa posachedwa. Njirayi ndi njira yabwinoko yofotokozera momwe khansa imakhalira ndikulabadira chithandizo.

• Gulu la Gulu 1: Gleason 6 kapena kuchepera (khansa yotsika)
• Gulu la 2: Gulu la Gleason 3 + 4 = 7 (khansa yapakatikati)
• Gulu la 3: Gulu la Gleason 4 + 3 = 7 (khansa yapakatikati)
• Gulu la 4: Gulu la Gleason 8 (khansa yayikulu)
• Gulu la Gulu 5: Gleason mphambu 9 mpaka 10 (khansa yayikulu)

Gulu locheperako likuwonetsa mwayi wabwino wothandizidwa bwino kuposa gulu lokwera. Gulu lapamwamba limatanthauza kuti maselo ambiri a khansa amawoneka osiyana ndi maselo abwinobwino. Gulu lapamwamba limatanthauzanso kuti chotupacho chitha kufalikira mwamphamvu.

Kulemba kumakuthandizani inu ndi dokotala kudziwa zomwe mungachite, komanso:

• Gawo la khansa, lomwe likuwonetsa kuchuluka kwa khansara
• Zotsatira zoyeserera za PSA
• Thanzi lanu lonse
• Chikhumbo chanu chochitidwa opareshoni, radiation, kapena mankhwala a mahomoni, kapena osalandira chithandizo chilichonse

Khansa ya prostate - Gleason; Prostate ya Adenocarcinoma - Gleason; Kalasi ya Gleason; Chiwerengero cha Gleason; Gulu la Gleason; Khansa ya prostate - gulu la 5 kalasi

Bostwick DG, Cheng L. Zotupa za prostate. Mu: Cheng L, MacLennan GT, Bostwick DG, olemba., Eds. Matenda Opangira Urologic. Wolemba 4. Philadelphia, PA: Elsevier; 2020: chap 9.

Epstein JI. Matenda a prostatic neoplasia.Mu: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, olemba. Campbell-Walsh-Wein Urology. Wolemba 12. Philadelphia, PA: Elsevier; 2021: chap 151.

Tsamba la National Cancer Institute. Chithandizo cha khansa ya Prostate (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/types/prostate/hp/prostate-kuchiza-pdq#_2097_toc. Idasinthidwa pa Julayi 22, 2020. Idapezeka pa Ogasiti 10, 2020.

• Khansa ya Prostate