Kusowa kwa IgA

Kuperewera kwa IgA ndiye vuto lomwe limafala kwambiri mthupi. Anthu omwe ali ndi vutoli ali ndi puloteni yocheperako kapena yopanda magazi yotchedwa immunoglobulin A.

Kuperewera kwa IgA nthawi zambiri kumachokera, zomwe zikutanthauza kuti zimadutsa m'mabanja. Komabe, palinso milandu yakusowa kwa mankhwala a IgA.

Itha kubadwa ngati njira yayikulu kwambiri yama autosomal kapena autosomal. Nthawi zambiri amapezeka mwa anthu ochokera ku Europe. Sizachilendo kwa anthu amitundu ina.

Anthu ambiri omwe ali ndi vuto la IgA yosankha alibe zisonyezo.

Ngati munthu ali ndi zizindikilo, atha kuphatikizanso magawo a:

• Bronchitis (matenda opita pandege)
• Kutsekula m'mimba
• Conjunctivitis (matenda amaso)
• Kutupa m'mimba, kuphatikizapo ulcerative colitis, matenda a Crohn, ndi matenda ngati sprue
• Matenda apakamwa
• Otitis media (matenda akumakutu apakati)
• Chibayo (matenda am'mapapu)
• Sinusitis (matenda a sinus)
• Matenda a khungu
• Matenda opatsirana apamwamba

Zizindikiro zina ndizo:

• Bronchiectasis (matenda omwe timapweya tating'onoting'ono m'mapapu timawonongeka ndikukula)
• Mphumu popanda chifukwa chodziwika

Pakhoza kukhala mbiri yabanja yakusowa kwa IgA. Mayeso omwe angachitike ndi awa:

• Miyeso yamagulu a IgG
• Kuchuluka kwa ma immunoglobulins
• Seramu immunoelectrophoresis

Palibe mankhwala enieni omwe akupezeka. Anthu ena pang'onopang'ono amakula milingo ya IgA popanda chithandizo.

Chithandizochi chimaphatikizapo kutenga njira zochepetsera kuchuluka kwa matenda. Maantibayotiki nthawi zambiri amafunikira kuti athetse matenda opatsirana ndi bakiteriya.

Ma immunoglobulins amaperekedwa kudzera mumitsempha kapena jakisoni kuti chitetezo chamthupi chitetezeke.

Chithandizo chamankhwala chodziletsa chimatengera vuto.

Chidziwitso: Anthu omwe ali ndi vuto lokwanira la IgA atha kupanga ma anti-IgA antibodies akapatsidwa mankhwala amwazi ndi ma immunoglobulins. Izi zitha kubweretsa chifuwa kapena kuwopsa kwa anaphylactic. Komabe, atha kupatsidwa chitetezo chokwanira cha IgA.

Kuperewera kwa IgA posankha sikovulaza kuposa matenda ena ambiri amthupi.

Anthu ena omwe ali ndi vuto la IgA adzachira pawokha ndikupanga IgA zochulukirapo kwazaka zambiri.

Matenda osokoneza bongo monga nyamakazi ya nyamakazi, systemic lupus erythematosus, ndi celiac sprue zitha kuyamba.

Anthu omwe ali ndi vuto la IgA amatha kupanga ma antibodies ku IgA. Zotsatira zake, amatha kukhala ndi zotulukapo zoopsa, ngakhale zowopsa pamoyo wokaika magazi ndi zinthu zamagazi.

Ngati muli ndi vuto la IgA, onetsetsani kuti mumatchula za omwe akukuthandizani ngati ma immunoglobulin kapena kuthiridwa magazi kumapangidwira ngati chithandizo chamtundu uliwonse.

Upangiri wa chibadwa ungakhale wofunikira kwa oyembekezera kukhala makolo omwe ali ndi mbiri yakubadwa kusowa kwa IgA.

Kuperewera kwa IgA; Kutetezedwa - kusowa kwa IgA; Kutetezedwa ndi chitetezo chamthupi - kusowa kwa IgA; Hypogammaglobulinemia - kusowa kwa IgA; Agammaglobulinemia - Kuperewera kwa IgA

• Ma antibodies

Cunningham-Rundles C. Matenda oyambira m'thupi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 236.

Sullivan KE, Buckley RH. Zolakwika zoyambirira zopanga ma antibody. Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 150.