Choriocarcinoma

Choriocarcinoma ndi khansa yomwe imakula mwachangu yomwe imapezeka mchiberekero cha mayi (m'mimba). Maselo achilendo amayamba m'minyewa yomwe nthawi zambiri imadzakhala placenta. Ichi ndi chiwalo chomwe chimakula panthawi yoyembekezera kudyetsa mwana wosabadwayo.

Choriocarcinoma ndi mtundu wa matenda opatsirana pogonana.

Choriocarcinoma ndi khansa yosowa yomwe imachitika ngati mimba yachilendo. Mwana atha kukhala ndi mimba yamtunduwu kapena ayi.

Khansara imathanso kupezeka pambuyo pathupi labwinobwino. Koma nthawi zambiri imachitika ndi mole yathunthu ya hydatidiform. Kukula kumeneku kumachitika m'mimba koyambirira kwa mimba. Minofu yachilendo yochokera ku mole imatha kupitilirabe kukula ngakhale itayesedwa kuchotsedwa, ndipo imatha kukhala khansa. Pafupifupi theka la azimayi onse omwe ali ndi choriocarcinoma anali ndi mole ya hydatidiform, kapena mimba yam'mimba.

Ma Choriocarcinomas amathanso kuchitika atakhala ndi pakati pomwe samapitilira (kupita padera). Zitha kupezekanso pambuyo pa ectopic pregnancy kapena chotupa chakumaliseche.

Chizindikiro chotheka ndikutuluka magazi mwachilendo mwa mayi mwa mayi yemwe posachedwa anali ndi mole ya hydatidiform kapena mimba.

Zizindikiro zina zitha kuphatikiza:

• Kutuluka magazi mosakhazikika
• Ululu, womwe ungagwirizane ndi kutuluka kwa magazi, kapena chifukwa chokulitsa thumba losunga mazira lomwe limakonda kupezeka ndi choriocarcinoma

Kuyezetsa mimba kumakhala koyenera, ngakhale simuli ndi pakati. Mulingo wa mahomoni apakati (HCG) udzakhala wokwera.

Kuyesedwa kwa m'chiuno kungapeze chiberekero chokulitsa ndi mazira ambiri.

Kuyezetsa magazi komwe kungachitike ndi monga:

• Zowonjezera seramu HCG
• Kuwerengera kwathunthu kwa magazi
• Ntchito ya impso
• Kuyesa kwa chiwindi

Kuyerekeza mayeso omwe angachitike ndi awa:

• Kujambula kwa CT
• MRI
• Pelvic ultrasound
• X-ray pachifuwa

Muyenera kuyang'aniridwa mosamala pambuyo pa mole ya hydatidiform kapena kumapeto kwa mimba. Kuzindikira koyambirira kwa choriocarcinoma kumatha kusintha zotsatira zake.

Mukapezeka, mudzayesedwa mosamala ndikuwunika kuti khansara siyinafalikire ziwalo zina. Chemotherapy ndiye mtundu waukulu wa chithandizo.

Hysterectomy kuchotsa chiberekero ndi chithandizo cha radiation sizofunikira kwenikweni.

Mutha kuchepetsa nkhawa zamankhwala ndikulowa nawo gulu lothandizira khansa. Kugawana ndi ena omwe akumana ndi mavuto omwe akukumana nawo kungakuthandizeni kuti musamve nokha.

Amayi ambiri omwe khansa yawo siyinafalikire amatha kuchira ndipo azitha kubereka. Choriocarcinoma imatha kubwerera mkati mwa miyezi ingapo mpaka zaka zitatu mutalandira chithandizo.

Vutoli ndi lovuta kuchiza ngati khansara yafalikira ndipo chimodzi kapena zingapo zotsatirazi zichitika:

• Matenda amafalikira mpaka pachiwindi kapena muubongo
• Mulingo wa mahomoni apakati (HCG) ndiwokwera kuposa 40,000 mIU / mL chithandizo chikayamba
• Khansa imabweranso mutalandira mankhwala a chemotherapy
• Zizindikiro kapena kutenga mimba kumachitika kwa miyezi yopitilira 4 mankhwala asanayambe
• Choriocarcinoma idachitika pambuyo pathupi zomwe zidabweretsa kubadwa kwa mwana

Amayi ambiri (pafupifupi 70%) omwe amakhala ndi malingaliro oyipa poyamba amapita kukakhululukidwa (boma lopanda matenda).

Itanani kuti mudzakumane ndi wothandizira zaumoyo wanu mukayamba kukhala ndi zizindikilo pasanathe chaka chimodzi mutakhala ndi hydatidiform mole kapena mimba.

Chorioblastoma; Chotupa cha trophoblastic; Chorioepithelioma; Gestational trophoblastic neoplasia; Khansa - choriocarcinoma

Tsamba la National Cancer Institute. Gestational trophoblastic disease treatment (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/cancertopics/pdq/treatment/gestationaltrophoblastic/HealthProfessional. Idasinthidwa pa Disembala 17, 2019. Idapezeka pa June 25, 2020.

Salani R, Bixel K, Copeland LJ. Matenda owopsa ndi mimba. Mu: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Obstetrics a Gabbe: Mimba Yachibadwa ndi Mavuto. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2021: chap 55.