Mayeso a Coombs

Mayeso a Coombs amayang'ana ma antibodies omwe amatha kumamatira m'maselo anu ofiira am'magazi ndikupangitsa kuti maselo ofiira afe msanga.

Muyenera kuyesa magazi.

Palibe kukonzekera kwapadera komwe kuyenera kuyesedwa.

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Pali mitundu iwiri ya mayeso a Coombs:

• Mwachindunji
• Osalunjika

Kuyesa kwachindunji kwa Coombs kumagwiritsidwa ntchito kuzindikira ma antibodies omwe amamatira pamwamba pamaselo ofiira amwazi. Matenda ndi mankhwala ambiri amatha kuyambitsa izi. Ma antibodies nthawi zina amawononga maselo ofiira am'magazi ndikupangitsa kuchepa kwa magazi. Wothandizira zaumoyo wanu angakulimbikitseni kuyesa uku ngati muli ndi zizindikilo za kuchepa kwa magazi m'thupi kapena jaundice (chikasu chachikopa kapena maso).

Kuyesa kosalunjika kwa Coombs kumayang'ana ma antibodies omwe akuyandama m'magazi. Ma antibodieswa amatha kumenyana ndi maselo ofiira amwazi. Kuyesaku kumachitika nthawi zambiri kuti mudziwe ngati mungayankhe magazi.

Zotsatira zabwinobwino zimatchedwa zotsatira zoyipa. Zimatanthawuza kuti panalibe kuwundana kwa maselo ndipo mulibe ma antibodies m'maselo ofiira ofiira.

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Kuyesa kwachilendo (koyenera) kwa Coombs kumatanthauza kuti muli ndi ma antibodies omwe amatsutsana ndi maselo ofiira amwazi. Izi zitha kuchitika chifukwa cha:

• Kutulutsa magazi m'thupi mwakachetechete
• Matenda a m'magazi a lymphocytic kapena matenda ofanana
• Matenda a m'magazi mwa ana obadwa kumene otchedwa erythroblastosis fetalis (amatchedwanso matenda a hemolytic a wakhanda)
• Matenda opatsirana mononucleosis
• Matenda a Mycoplasma
• Chindoko
• Njira lupus erythematosus
• Kuikidwa magazi, monga m'modzi chifukwa chamagulu osagwirizana a magazi

Zotsatira zakumayeso zitha kukhalanso zachilendo popanda chifukwa chomveka, makamaka pakati pa okalamba.

Kuyezetsa kozolowereka kosadziwika bwino kwa Coombs kumatanthauza kuti muli ndi ma antibodies omwe angalimbane ndi maselo ofiira omwe thupi lanu limawawona ngati lachilendo. Izi zitha kunena kuti:

• Erythroblastosis fetalis
• Masewera osagwirizana amwazi (mukamagwiritsa ntchito malo osungira magazi)

Pali chiopsezo chochepa chotenga magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kutenga magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zomwe zimakoka magazi ndi zochepa, koma mwina ndi izi:

• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi omanga pansi pa khungu)
• Kutaya magazi kwambiri
  
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Mayeso a antiglobulin mwachindunji; Mayeso antiglobulin osadziwika; Kuchepa magazi - hemolytic

Elghetany MT, Schexneider KI, mavuto a Banki K. Erythrocytic. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 32.

Michel M. Autoimmune ndi intravascular hemolytic anemias. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 151.