Phatikizani gawo 3 (C3)

Wowonjezera C3 ndi kuyezetsa magazi komwe kumayeza ntchito ya protein inayake.

Puloteni iyi ndi gawo limodzi lamagulu othandizira. Njira yothandizirayi ndi gulu la mapuloteni pafupifupi 60 omwe ali m'madzi am'magazi kapena pamaselo ena. Mapuloteniwa amagwira ntchito ndi chitetezo cha mthupi lanu ndipo amatenga gawo limodzi kuteteza thupi ku matenda, ndikuchotsa maselo akufa ndi zinthu zakunja. Nthawi zambiri, anthu amatha kulandira kuchepa kwa mapuloteni ena othandizira. Anthuwa amatha kudwala matenda ena kapena matenda omwe amadzichitira okha.

Pali mapuloteni asanu ndi anayi akulu othandizira. Amatchedwa C1 kudzera C9. Nkhaniyi ikufotokoza mayeso omwe amayesa C3.

Magazi amatengedwa kuchokera mumtsempha. Nthawi zambiri, mtsempha wochokera mkatikati mwa chigongono kapena kumbuyo kwa dzanja umagwiritsidwa ntchito.

Njirayi ndi iyi:

• Tsambali limatsukidwa ndi mankhwala opha tizilombo.
• Wothandizira zaumoyo amakulunga kansalu kotanuka kumanja kumtunda kuti apanikizire malowa ndikupangitsa mtsempha kutupika ndi magazi.
• Woperekayo amalowetsa singano mumtambo.
• Mwazi umasonkhanitsa mu chotengera chotsitsimula kapena chubu cholumikizidwa ndi singano. Lamba womata wachotsedwa m'manja mwanu.
• Magazi akangotoleredwa, singano imachotsedwa. Malo obowola amafundidwa kuti asiye magazi.

Kwa makanda kapena ana aang'ono, chida chakuthwa chotchedwa lancet chitha kugwiritsidwa ntchito kuboola khungu ndikuthira magazi.Mwazi umasonkhanitsa mu chubu chaching'ono chagalasi chotchedwa pipette, kapena pagawo loyeserera kapena loyesa. Bandeji itha kuyikidwa pamalopo ngati pali magazi.

Palibe kukonzekera kwapadera kofunikira.

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kuti amangobaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupindika.

C3 ndi C4 ndizomwe zimayeza kwambiri zowonjezera.

Mayeso othandizira amatha kugwiritsidwa ntchito kuwunika anthu omwe ali ndi vuto lodziyimira palokha. Zachitika kuti muwone ngati chithandizo cha matenda awo chikugwira ntchito. Makina othandizira akamatsegulidwa panthawi yotupa, milingo yamapuloteni othandizira imatha kutsika. Mwachitsanzo, anthu omwe ali ndi lupus erythematosus yogwira akhoza kukhala ndi zochepera kuposa zachilendo zama protein othandizira a C3 ndi C4.

Ntchito zowonjezera zimasiyana mthupi lonse. Mwachitsanzo, mwa anthu omwe ali ndi nyamakazi ya nyamakazi, ntchito yothandizirana m'magazi imatha kukhala yachilendo kapena yayikulu kuposa yachibadwa, koma yotsika kwambiri kuposa yachibadwa mumadzimadzi olowa.

Mayesowo amathanso kuchitidwa pazifukwa izi:

• Matenda a fungal
• Galamu alibe septicemia
• Matenda opatsirana pogonana, monga malungo
• Paroxysmal usiku wotchedwa hemoglobinuria (PNH)
• Chodabwitsa

Mulingo woyenera ndi mamiligalamu 88 mpaka 201 pa desilita imodzi (mg / dL) (0.88 mpaka 2.01 g / L).

Chidziwitso: Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pama laboratories osiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Zitsanzo pamwambapa zikuwonetsa muyeso wamba wazotsatira zamayesowa. Ma labotale ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana.

Ntchito zowonjezera zowonjezera zitha kuwoneka mu:

• Khansa
• Zilonda zam'mimba

Kuchepetsa ntchito zowonjezera kumawoneka mu:

• Matenda a bakiteriya (makamaka Neisseria)
• Matenda a chiwindi
• Glomerulonephritis
• Chiwindi
• Cholowa cholowa angioedema
• Kukaniza kukweza impso
• Lupus nephritis
• Kusowa zakudya m'thupi
• Njira lupus erythematosus
• Kawirikawiri timakwaniritsa zoperewera
  
  

Zowopsa zomwe zimakhudza kukoka magazi ndizochepa, koma zimatha kuphatikiza:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Hematoma (magazi akuchuluka pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Chowonjezeracho chimakhala chosiyanasiyana chomwe chimachitika m'magazi. Kutuluka kumatsegulira mapuloteni othandizira. Zotsatira zake ndi zida zowukira zomwe zimapanga mabowo m'mimba mwa mabakiteriya, ndikuwapha. C3 imamangirira mabakiteriya ndikuwapha mwachindunji.

C3

• Kuyezetsa magazi

Chernecky CC, Berger BJ. C3 wothandizira (beta-1c-globulin) - seramu. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 267-268.

Holers VM. Kuphatikiza ndi omwe amalandila: kuzindikira kwatsopano ku matenda amunthu. Annu Rev Immunol. 2014; 32: 433-459. PMID: 24499275 www.ncbi.nlm.nih.gov/pubmed/24499275. (Adasankhidwa)

Massey HD, McPherson RA, Huber SA, Jenny NS. Amkhalapakati otupa: wothandizira. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 47.

Merle NS, Mpingo SE, Fremeaux-Bacchi V, Roumenina LT. Onjezerani dongosolo gawo I - njira zoyeserera ndi kuwongolera. Kutsogolo Immunol. 2015; 6: 262. PMID: 26082779 www.ncbi.nlm.nih.gov/pubmed/26082779.

Pezani nkhaniyi pa intaneti Merle NS, Noe R, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT. Kuthandizira gawo lachiwiri: gawo loteteza chitetezo. Kutsogolo Immunol. 2015; 6: 257. PMID: 26074922 www.ncbi.nlm.nih.gov/pubmed/26074922. (Adasankhidwa)

Morgan BP, Harris CL. Kuphatikizana, cholinga chothandizira matenda opatsirana komanso otupa. Nat Rev Mankhwala Osokoneza bongo. 2015; 14 (12): 857-877. PMID: 26493766 www.ncbi.nlm.nih.gov/pubmed/26493766. (Adasankhidwa)