Seramu globulin electrophoresis

Chiyeso cha serum globulin electrophoresis chimayeza kuchuluka kwa mapuloteni otchedwa globulins mgulu lamadzi m'magazi. Amadzimadzi amenewa amatchedwa seramu.

Muyenera kuyesa magazi.

Labu, waluso amaika magazi ake papepala lapadera ndikugwiritsa ntchito magetsi. Mapuloteni amapita papepala ndikupanga magulu omwe amawonetsa kuchuluka kwa protein iliyonse.

Tsatirani malangizo ngati muyenera kusala kudya musanayesedwe.

Mankhwala ena angakhudze zotsatira za kuyesaku. Wothandizira zaumoyo wanu angakuuzeni ngati mukufuna kusiya kumwa mankhwala aliwonse. Osayimitsa mankhwala aliwonse musanalankhule ndi omwe amakupatsani.

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Kuyesaku kumachitika kuti tione mapuloteni a globulin m'magazi. Kudziwa mitundu ya ma globulini kumatha kuthandizira kuzindikira zovuta zina zamankhwala.

Maglobulini amagawika m'magulu atatu: alpha, beta, ndi gamma globulins. Gamma globulins amaphatikizapo mitundu yambiri ya ma antibodies monga ma immunoglobulins (Ig) M, G, ndi A.

Matenda ena amathandizidwa ndikupanga ma immunoglobulins ambiri. Mwachitsanzo, Waldenstrom macroglobulinemia ndi khansa yamagazi ena oyera. Amalumikizidwa ndikupanga ma antibodies ambiri a IgM.

Mitundu yofanana yamtengo wapatali ndi iyi:

• Serum globulin: 2.0 mpaka 3.5 magalamu pa deciliter (g / dL) kapena magalamu 20 mpaka 35 pa lita (g / L)
• Gawo la IgM: mamiligalamu 75 mpaka 300 pa desilita (mg / dL) kapena mamiligalamu 750 mpaka 3,000 pa lita (mg / L)
• Gawo la IgG: 650 mpaka 1,850 mg / dL kapena 6.5 mpaka 18.50 g / L.
• Gawo la IgA: 90 mpaka 350 mg / dL kapena 900 mpaka 3,500 mg / L.

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Kuchuluka kwa gamma globulin mapuloteni atha kuwonetsa:

• Matenda oopsa
• Khansa yamagazi yamagazi ndi mafupa kuphatikiza ma myeloma angapo, ndi ma lymphomas ndi leukemias
• Matenda osowa chitetezo mthupi
• Matenda a kutupa kwanthawi yayitali (mwachitsanzo, nyamakazi ya nyamakazi ndi systemic lupus erythematosus)
• Waldenström macroglobulinemia

Pali chiopsezo chochepa kwambiri chokhudzidwa ndi magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina, komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kutenga magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zomwe zimakoka magazi ndi zochepa, koma mwina ndi izi:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi omanga pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Kuchuluka kwa ma immunoglobulins

• Kuyezetsa magazi

Chernecky CC, Berger BJ. Immunoelectrophoresis - seramu ndi mkodzo. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 667-692.

Dominiczak MH, Fraser WD. Mapuloteni amwazi ndi plasma. Mu: Baynes JW, Dominiczak MH, olemba., Eds. Sayansi Yachipatala Yamankhwala. 5th ed. Philadelphia, PA: Elsevier; 2019: mutu 40.