Eosinophilic esophagitis

Eosinophilic esophagitis imaphatikizapo kuchuluka kwa maselo oyera am'magazi, otchedwa eosinophils, m'mbali mwa khosi lanu. M'mero ​​ndi chubu chomwe chimanyamula chakudya kuchokera pakamwa panu kupita kumimba kwanu. Kuchuluka kwa maselo oyera am'magazi kumachitika chifukwa cha zakudya, ma allergen, kapena asidi Reflux.

Zomwe zimayambitsa eosinophilic esophagitis sizidziwika. Amakhulupirira kuti chitetezo chamthupi pachakudya china chimadzetsa ma eosinophil. Zotsatira zake, akalowa am'mimbamo amatupa ndikutupa.

Anthu ambiri omwe ali ndi vutoli ali ndi mabanja kapena mbiri yakale ya chifuwa kapena mphumu. Zomwe zimayambitsa monga nkhungu, mungu ndi fumbi zimathandizanso.

Eosinophilic esophagitis imatha kukhudza ana ndi akulu omwe.

Zizindikiro mwa ana ndi izi:

• Mavuto kudyetsa kapena kudya
• Kupweteka m'mimba
• Kusanza
• Mavuto kumeza
• Chakudya chikukakamira pammero
• Kuchepetsa kunenepa kapena kuwonda, kukula kosauka, ndi kuperewera kwa zakudya m'thupi

Zizindikiro mwa akulu ndizo:

• Chakudya chimakanirira mukameza (dysphagia)
• Kupweteka pachifuwa
• Kutentha pa chifuwa
• Kumva kupweteka m'mimba
• Kubwerera m'mbuyo kwa chakudya chosagwiritsidwa ntchito (kubwezeretsanso)
• Reflux yomwe siyikhala bwino ndi mankhwala

Wothandizira zaumoyo wanu adzalemba mbiri yakale ndikuwunika. Izi zimachitika kuti muwone ngati ali ndi vuto la chakudya komanso kuti athetse zina, monga gastroesophageal Reflux matenda (GERD).

Mayeso omwe angachitike ndi awa:

• Kuyesa magazi
• Mayeso a khungu la ziwengo
• Pamwamba endoscopy
• Chiwombankhanga cha chikhomo

Palibe mankhwala kapena chithandizo chilichonse cha eosinophilic esophagitis. Chithandizo chimaphatikizapo kusamalira zakudya zanu komanso kumwa mankhwala.

Ngati mutapezeka kuti muli ndi vuto la chakudya, mungauzidwe kuti mupewe zakudya zimenezo. Kapena mungapewe zakudya zonse zomwe zimayambitsa vuto ili. Zakudya zomwe anthu ambiri amafunika kupewa monga nsomba, mazira, mtedza, soya, tirigu, ndi mkaka. Kuyesa kwa ziwengo kumatha kupeza zakudya zoyenera kupewa.

Proton pump inhibitors amatha kuthandizira kuwongolera zizindikilo, koma sizithandiza vuto lomwe limayambitsa zizindikilo.

Wothandizira anu akhoza kukupatsani mankhwala otchedwa steroids omwe amatengedwa pakamwa kapena kupuma. Muthanso kumwa ma steroids kwakanthawi kochepa. Ma steroids am'mutu samakhala ndi zovuta zofananira ngati ma oral steroids.

Mukayamba kuchepa kapena kupindika, njira yotsegulira kapena kutambasula dera lingafunike.

Inu ndi omwe akukuthandizani mugwirira ntchito limodzi kuti mupeze dongosolo lamankhwala lomwe lingakuthandizeni kwambiri.

Magulu othandizira monga American Partnership for Eosinophilic Disorders angakuthandizeni kumvetsetsa zambiri za eosinophilic esophagitis. Muthanso kuphunzira njira zokuthandizani kuthana ndi matendawa.

Eosinophilic esophagitis ndi matenda a nthawi yayitali (osachiritsika) omwe amabwera ndikupita m'moyo wamunthu.

Zovuta zomwe zingakhalepo zingaphatikizepo:

• Kuchepetsa kwa kholingo (kukhazikika)
• Chakudya chimakakamira m'mimba (chofala mwa ana ndi akulu omwe)
• Kutupa kwakukulu ndi kukwiya kwa mimbayo

Lumikizanani ndi omwe amakupatsani ngati muli ndi zizindikilo za eosinophilic esophagitis.

• Minyewa
• Matupi awo sagwirizana pakhungu kapena poyambira
• Zochita zapakati pazomwe zimayesedwa

Chen JW, Kao JY. Eosinophilic esophagitis: zosintha pamayendedwe ndi mikangano. BMJ. 2017; 359: j4482. PMID: 29133286 pubmed.ncbi.nlm.nih.gov/29133286/.

Falk GW, Katzka DA. Matenda am'mimba. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 129.

Groetch M, Venter C, Skypala I, et al; (Adasankhidwa) Eosinophilic Gastrointestinal Disorders Committee ya American Academy of Allergy, Phumu ndi Immunology. Mankhwala opatsirana ndi kasamalidwe kabwino ka eosinophilic esophagitis: lipoti la gulu la American Academy of Allergy, Asthma, and Immunology. J Allergy Clin Immunol Pract. 2017; 5 (2): 312-324.e29. (Adasankhidwa) PMID: 28283156 pubed.ncbi.nlm.nih.gov/28283156/.

Khan S. Eosinophilic esophagitis, mapiritsi esophagitis, ndi matenda opatsirana opatsirana. Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 350.