Levodopa ndi Carbidopa

Zamkati

• Musanatenge levodopa ndi carbidopa,
• Levodopa ndi carbidopa zingayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa mu gawo la MAWONEKEDWE, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Kuphatikiza kwa levodopa ndi carbidopa kumagwiritsidwa ntchito pochiza zizindikilo za matenda a Parkinson komanso zisonyezo ngati za Parkinson zomwe zimatha kuchitika pambuyo pa encephalitis (kutupa kwa ubongo) kapena kuvulala kwamanjenje komwe kumayambitsa poyizoni wa carbon monoxide kapena poyizoni wa manganese. Zizindikiro za Parkinson, kuphatikiza kunjenjemera (kunjenjemera), kuuma, komanso kuyenda pang'onopang'ono, zimachitika chifukwa chosowa dopamine, chinthu chachilengedwe chomwe chimapezeka nthawi zambiri muubongo. Levodopa ali mgulu la mankhwala otchedwa central system system agents. Zimagwira ntchito potembenuzidwa kukhala dopamine muubongo. Carbidopa ali mgulu la mankhwala otchedwa decarboxylase inhibitors. Zimagwira ntchito popewa levodopa kuti isadafike isanafike kuubongo. Izi zimathandizira kuchepa kwa levodopa, komwe kumayambitsa nseru komanso kusanza.

Kuphatikiza kwa levodopa ndi carbidopa kumabwera ngati piritsi lokhazikika, piritsi losweka pakamwa, piritsi lotulutsa (lotenga nthawi yayitali), ndi kapisozi wautali (wotenga nthawi yayitali) woti atenge pakamwa. Kuphatikiza kwa levodopa ndi carbidopa kumabweranso ngati kuyimitsidwa (madzi) kuti mupatse m'mimba mwanu kudzera mu chubu cha PEG-J (chubu cholowetsedwa kudzera pakhungu ndi m'mimba) kapena nthawi zina kudzera pa chubu cha naso-jejunal (NJ; a chubu cholowetsedwa m'mphuno ndi m'mimba mwanu) pogwiritsa ntchito mpope wapadera. Mapiritsi omwe amadzaza pakamwa nthawi zambiri amatengedwa katatu kapena kanayi patsiku. Piritsi lotulutsira nthawi zambiri limatengedwa kawiri kapena kanayi patsiku. Kapsule womasulidwa nthawi zambiri amatengedwa katatu kapena kasanu patsiku. Kuyimitsidwa nthawi zambiri kumaperekedwa ngati mlingo wam'mawa (woperekedwa ndi kulowetsedwa kwa mphindi 10 mpaka 30) kenako ngati mlingo wopitilira (woperekedwa ndi kulowetsedwa kwa maola 16), ndikuwonjezeka kopitilira kamodzi kokha maola awiri aliwonse pakufunika kuwongolera zizindikiro. Tengani levodopa ndi carbidopa mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani levodopa ndi carbidopa monga momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi otulutsidwa otalikiratu; musatafune kapena kuwaphwanya.

Kumeza lonse makapisozi kumasulidwa lonse; osazitafuna, kuzigawa, kapena kuziphwanya. Tengani mlingo woyamba wamasamba 1 mpaka 2 musanadye. Ngati zikukuvutani kumeza, mutha kutsegula mosamala kapule yotulutsidwayo, ndi kumwaza zonsezo mu supuni 1 mpaka 2 (15 mpaka 30 mL) msuzi wa apulo, ndikudya msanganizo nthawi yomweyo. Osasunga chisakanizocho kuti mugwiritse ntchito mtsogolo.

Kuti mutenge piritsi lomwe limasweka pakamwa, chotsani piritsi mu botolo pogwiritsa ntchito manja ouma ndikuyika pakamwa panu.Piritsi limasungunuka mwachangu ndipo limatha kumezedwa ndi malovu. Palibe madzi omwe amafunikira kuti amezere mapiritsi omwe amafa.

Ngati mukusintha kuchokera ku levodopa (Dopar kapena Larodopa; sichikupezeka ku US) ndikuphatikiza levodopa ndi carbidopa, tsatirani malangizo a dokotala wanu. Mwinamwake mudzauzidwa kudikirira osachepera maola 12 mutatha mlingo wanu wotsiriza wa levodopa kuti mutenge mlingo wanu woyamba wa levodopa ndi carbidopa.

Dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa levodopa ndi carbidopa ndipo pang'onopang'ono muwonjezere kuchuluka kwanu kwa piritsi lomwe limagawanika nthawi zonse kapena pakamwa tsiku lililonse kapena tsiku lililonse ngati pakufunika kutero. Dokotala wanu akhoza kuwonjezera pang'onopang'ono mlingo wanu wa piritsi lotulutsidwa kapena kapisozi pakatha masiku atatu pakufunika kutero.

Kuti muyimitse, dokotala wanu kapena wamankhwala akuwonetsani momwe mungagwiritsire ntchito pampu popereka mankhwala anu. Werengani malangizo olembedwa omwe amabwera ndi pampu ndi mankhwala. Yang'anani zithunzizo mosamala ndipo onetsetsani kuti mukuzindikira magawo onse a pampu ndikufotokozera mafungulo. Funsani dokotala wanu kapena wamankhwala kuti afotokoze gawo lirilonse lomwe simukumvetsa.

Kuyimitsidwa kwa Levodopa ndi carbidopa kumabwera mu kaseti yogwiritsira ntchito kamodzi kuti mugwirizane ndi pampu yomwe idzawongolera kuchuluka kwa mankhwala omwe mungalandire mukamulowetsedwa. Musanagwiritse ntchito, chotsani makaseti okhala ndi mankhwalawo mufiriji ndikuwalola kuti azikhala kutentha kwa mphindi 20. Musagwiritsenso ntchito kaseti kapena kuyigwiritsa ntchito kwa maola 16. Tayani kaseti kumapeto kwa kulowetsedwa ngakhale mutakhala ndi mankhwala.

Mukayamba kumwa levodopa ndi carbidopa kuyimitsidwa, dokotala wanu amasintha mmawa wanu komanso kuchuluka kwa kulowetsedwa kwaposachedwa ndipo mwina mayeza a mankhwala ena a Parkinson kuti athetse matenda anu. Zimatengera pafupifupi masiku asanu kuti mufike poyimitsa, koma mayendedwe anu angafunike kusinthidwa kanthawi kutengera kuyankha kwanu kwa mankhwala. Muyeso wanu woyimitsidwa adzakulowetsani pampu yanu ndi dokotala. Musasinthe mlingo kapena zosintha pampu yanu pokhapokha mukauzidwa ndi dokotala wanu. Samalani kuti muwonetsetse kuti chubu chanu cha PEG-J sichikhala cholumikizidwa, chopindika, kapena kutsekedwa chifukwa izi zingakhudze kuchuluka kwa mankhwala omwe mumalandira.

Levodopa ndi carbidopa amawongolera matenda a Parkinson koma samachiritsa. Zitha kutenga miyezi ingapo musanapindule ndi levodopa ndi carbidopa. Pitirizani kumwa levodopa ndi carbidopa ngakhale mukumva bwino. Osasiya kumwa levodopa ndi carbidopa osalankhula ndi dokotala. Ngati mwasiya mwadzidzidzi kumwa levodopa ndi carbidopa, mutha kukhala ndi matenda oyambitsa malungo, minofu yolimba, mayendedwe achilendo a thupi, ndi chisokonezo. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono. Ngati dokotala atakuwuzani kuti musiye kuyimitsidwa kwa levodopa ndi carbidopa, katswiri wazachipatala adzachotsa chubu chanu cha PEG-J; musachotse chubu nokha.

Funsani wamankhwala kapena dokotala wanu kuti akupatseni pepala lazidziwitso zaopanga za levodopa ndi carbidopa komanso Buku la Medication la levodopa ndi kuyimitsidwa kwa carbidopa.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge levodopa ndi carbidopa,

• Uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la levodopa ndi carbidopa mankhwala aliwonse, kapena zosakaniza zilizonse m'mapiritsi a levodopa ndi carbidopa, makapisozi, kapena kuyimitsidwa. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo ngati mukumwa phenelzine (Nardil) kapena tranylcypromine (Parnate) kapena ngati mwasiya kuwamwa m'masabata awiri apitawa. Dokotala wanu angakuuzeni kuti musatenge levodopa ndi carbidopa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: antidepressants ('mood lifters') monga amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), ndi trimipramine (Surmontil); mankhwala; haloperidol (Haldol); ipratropium (Atrovent); chitsulo mapiritsi ndi mavitamini munali chitsulo; isocarboxazid (Marplan); isoniazid (INH, Nydrazid); mankhwala a kuthamanga kwa magazi, matenda opweteka m'mimba, matenda amisala, kuyenda koyenda, nseru, zilonda zam'mimba, kapena mavuto amikodzo; metoclopramide (Reglan); mankhwala ena a matenda a Parkinson; papaverine (Pavabid); phenytoin (Dilantin); rasagiline (Azilect); risperidone (Risperdal); mankhwala ogonetsa; selegiline (Emsam, Eldepryl, Zelapar); mapiritsi ogona; tetrabenazine (Xenazine); ndi zotontholetsa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mwakhalapo ndi glaucoma, khansa ya pakhungu (khansa yapakhungu), kapena kukula kwa khungu komwe sikunapezeke. Dokotala wanu angakuuzeni kuti musatenge levodopa ndi carbidopa.
• uzani dokotala wanu ngati mwakhalapo kapena mwakhalapo ndi vuto la mahomoni; mphumu; emphysema; matenda amisala; matenda ashuga; zilonda zam'mimba; matenda a mtima; kugunda kwamtima kosasintha; kapena chotengera chamagazi, mtima, impso, chiwindi kapena matenda am'mapapo. Ngati mukugwiritsa ntchito kuyimitsidwa kwa levodopa ndi carbidopa, uzani dokotala wanu ngati mwachitidwapo opaleshoni yam'mimba, mavuto amitsempha, kuthamanga kwa magazi, kapena kukomoka.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga levodopa ndi carbidopa, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa levodopa ndi carbidopa.
• muyenera kudziwa kuti levodopa ndi carbidopa zitha kukupangitsani kugona kapena zingakupangitseni kuti mugone modzidzimutsa mukamagwira ntchito tsiku ndi tsiku. Mwina simungamve kugona kapena kukhala ndi zizindikiro zina musanagone mwadzidzidzi. Osayendetsa galimoto, kugwiritsa ntchito makina, kugwira ntchito pamalo okwera, kapena kuchita nawo zoopsa pachiyambi cha chithandizo chanu mpaka mutadziwa momwe mankhwalawo amakukhudzirani. Ngati mumagona modzidzimutsa pamene mukuchita zinthu monga kuonera TV, kulankhula, kudya, kapena kukwera galimoto, kapena ngati mutagona kwambiri, makamaka masana, itanani dokotala wanu. Osayendetsa, kugwira ntchito m'malo okwezeka, kapena kugwiritsa ntchito makina mpaka mutalankhula ndi dokotala wanu.
• Funsani dokotala wanu za zakumwa zoledzeretsa pamene mukumwa levodopa ndi carbidopa. Mowa umatha kukulitsa mavuto obwera chifukwa cha levodopa ndi carbidopa.
• muyenera kudziwa kuti anthu ena omwe amamwa mankhwala monga levodopa ndi carbidopa adayamba kutchova juga kapena zolakalaka zina kapena zikhalidwe zomwe zinali zovuta kapena zachilendo kwa iwo, monga zilakolako zakugonana kapena zizolowezi zina. Palibe chidziwitso chokwanira chodziwitsa ngati anthu adayamba chifukwa cha kumwa mankhwalawo kapena pazifukwa zina. Itanani dokotala wanu ngati muli ndi chidwi chofuna kutchova juga komwe kuli kovuta kuletsa, muli ndi chidwi chachikulu, kapena simutha kudziletsa. Uzani achibale anu za chiopsezo ichi kuti athe kuyimbira adokotala ngakhale simukuzindikira kuti kutchova juga kwanu kapena zina zilizonse zolimbikitsa kapena zikhalidwe zina zasanduka vuto.
• muyenera kudziwa kuti mukamamwa levodopa ndi carbidopa, malovu anu, mkodzo wanu, kapena thukuta lanu limatha kukhala lakuda (lofiira, lofiirira, kapena lakuda). Izi ndizopanda vuto, koma zovala zanu zimatha kudetsedwa.
• muyenera kudziwa kuti levodopa ndi carbidopa zimatha kuyambitsa chizungulire, mutu wopepuka, komanso kukomoka mukadzuka mwachangu pamalo abodza. Izi ndizofala kwambiri mukayamba kumwa levodopa ndi carbidopa. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire.
• ngati muli ndi phenylketonuria (PKU, mkhalidwe wobadwa nawo momwe muyenera kudya chakudya chapadera kuti muchepetse kuchepa kwamaganizidwe), muyenera kudziwa kuti mapiritsi omwe amawonongeka pakamwa amakhala ndi aspartame yomwe imapanga phenylalanine.

Lankhulani ndi dokotala ngati mukufuna kusintha zakudya zanu kukhala zakudya zomwe zili ndi zomanga thupi zambiri, monga nyama, nkhuku, ndi mkaka.

Tengani mlingo womwe umasowa piritsi lokhazikika, piritsi losweka pakamwa, piritsi yotulutsa nthawi yayitali, kapena kapisozi wokulitsa (wautali) mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Ngati mukugwiritsa ntchito levodopa ndi carbidopa kulowetsedwa mkati ndikuchotsa pampu yolowetsedwa kwakanthawi kochepa (ochepera maola 2), kupatula kusiyanitsa koyenera usiku, funsani dokotala ngati mungagwiritse ntchito mlingo wowonjezera musanatulutse pampu. Ngati mpope wolowetsedwa udzawonongeka kwa nthawi yayitali kuposa maola 2, itanani dokotala wanu; mwina mudzalangizidwa kutenga levodopa ndi carbidopa pakamwa pomwe simukugwiritsa ntchito kuyimitsidwa.

Levodopa ndi carbidopa zingayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• chizungulire
• kusowa chilakolako
• kutsegula m'mimba
• pakamwa pouma
• kupweteka mkamwa ndi mmero
• kudzimbidwa
• sinthani tanthauzo la kukoma
• kuyiwala kapena kusokonezeka
• manjenje
• maloto olakwika
• kuvuta kugona kapena kugona
• mutu
• kufooka

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa mu gawo la MAWONEKEDWE, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kusuntha kosazolowereka kapena kosalamulirika pakamwa, lilime, nkhope, mutu, khosi, mikono, ndi miyendo
• kuthamanga, kusasinthasintha, kapena kugunda kwamtima
• thukuta lowonjezeka
• kupweteka pachifuwa
• kukhumudwa
• malingaliro a imfa kapena kudzipha
• kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• zovuta kumeza kapena kupuma
• ming'oma
• kufooka, dzanzi, kapena kutayika kwa zala kapena mapazi
• ngalande, kufiira, kutupa, kupweteka, kapena kutentha kumadera ozungulira chubu lanu la PEG-J (ngati mukumitsa levodopa ndi kuyimitsidwa kwa carbidopa)
• mipando yakuda ndi yodikira
• magazi ofiira m'mipando
• malungo
• kupweteka m'mimba
• nseru
• kusanza
• masanzi amagazi
• kusanza komwe kumawoneka ngati malo a khofi

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Sungani makaseti okhala ndi levodopa ndi kuyimitsidwa kwa carbidopa mufiriji mu katoni yawo yoyambirira, yotetezedwa ku kuwala. Osazizira kuyimitsidwa.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone yankho lanu ku levodopa ndi carbidopa.

Musanayesedwe mu labotale, auzeni adotolo ndi ogwira nawo ntchito kuti mukumwa levodopa ndi carbidopa.

Levodopa ndi carbidopa zimatha kutha nthawi yayitali kapena munthawi zina masana. Itanani dokotala wanu ngati matenda anu a Parkinson (kugwedezeka, kuuma, ndi kuchepa kwa kuyenda) kumakulirakulira kapena kusiyanasiyana.

Pamene thanzi lanu likuyenda bwino ndipo ndikosavuta kuti musamuke, samalani kuti musapitilize kuchita masewera olimbitsa thupi. Wonjezerani zochita zanu pang'onopang'ono kuti mupewe kugwa ndi kuvulala.

Levodopa ndi carbidopa zimatha kubweretsa zotsatira zabodza mumayeso amkodzo a shuga (Clinistix, Clinitest, ndi Tes-Tape) ndi ketoni (Acetest, Ketostix, ndi Labstix).

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Duopa^®
• Parcopa^®¶
• Zosintha^®
• Sinemet^®

• Stalevo^® (okhala ndi Carbidopa, Entacapone, Levodopa)

^¶ Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.