Jekeseni wa Irinotecan

Zamkati

• Asanalandire irinotecan,
• Irinotecan imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo:

Jekeseni wa Irinotecan uyenera kuperekedwa moyang'aniridwa ndi dokotala yemwe amadziwa bwino kupereka mankhwala a chemotherapy a khansa.

Mutha kukhala ndi zizindikiro zotsatirazi mukalandira mankhwala a irinotecan kapena kwa maola 24 pambuyo pake: mphuno yothamanga, malovu owonjezera, ana akuchepa (mabwalo akuda pakati pa maso), maso amadzi, thukuta, kutuluka m'mimba, kutsekula m'mimba ( Nthawi zina amatchedwa 'kutsegula m'mimba msanga'), ndi kukokana m'mimba. Uzani dokotala wanu ngati mukukumana ndi izi. Dokotala wanu akhoza kukupatsani mankhwala kuti muchepetse kapena kuchiza izi.

Muthanso kukhala ndi matenda otsekula m'mimba (omwe nthawi zina amatchedwa '' kutsegula m'mimba mochedwa '') patadutsa maola 24 mutalandira irinotecan. Kutsekula kwamtunduwu kumatha kuopseza moyo chifukwa kumatha kukhala nthawi yayitali ndikupangitsa kuti madzi asowe m'thupi, matenda, kufooka kwa impso, ndi mavuto ena. Uzani dokotala wanu ngati mwakhalapo ndi zotsekeka m'matumbo (kutsekeka m'matumbo mwanu). Uzani dokotala ndi wamankhwala ngati mukumwa mankhwala aliwonse awa: mankhwala ena a chemotherapy a khansa; okodzetsa ('mapiritsi amadzi'); kapena mankhwala ofewetsa tuvi tolimba monga bisacodyl (Dulcolax) kapena senna (ku Correctol, Ex-Lax, Peri-Colace, Senokot).

Musanayambe kumwa mankhwala ndi irinotecan, lankhulani ndi dokotala wanu zomwe muyenera kuchita ngati mwachedwa kutsegula m'mimba. Dokotala wanu angakuuzeni kuti muzisunga loperamide (Imodium AD) pafupi kuti muthe kuyitenga nthawi yomweyo mukayamba kutsekula m'mimba mochedwa. Dokotala wanu angakuuzeni kuti mutenge loperamide pafupipafupi usana ndi usiku. Onetsetsani kuti mukutsatira malangizo a dokotala kuti mutenge loperamide; izi zidzakhala zosiyana ndi malangizo omwe adzasindikizidwe phukusi la loperamide. Dokotala wanu adzakuuzaninso zakudya zomwe muyenera kudya komanso zakudya zomwe muyenera kupewa kupewa kutsekula m'mimba mukamalandira chithandizo. Imwani zamadzi ambiri ndikutsatira mosamala izi.

Itanani dokotala wanu nthawi yoyamba mukakhala ndi matenda otsekula m'mimba mukamalandira chithandizo. Itanani dokotala wanu nthawi yomweyo ngati mukukumana ndi izi: malungo (kutentha kwambiri kuposa 100.4 ° F); kugwedeza kuzizira; chimbudzi chakuda kapena chamagazi; kutsegula m'mimba komwe sikutha mkati mwa maola 24; mutu wopepuka, chizungulire, kapena kukomoka; kapena kusanza kwambiri ndi kusanza komwe kumakulepheretsani kumwa chilichonse. Dokotala wanu amakuyang'anirani mosamala ndipo akhoza kukuchitirani zamadzimadzi kapena maantibayotiki ngati kuli kofunikira.

Irinotecan imatha kuchepa kwama cell am'magazi omwe amapangidwa ndi mafupa anu. Uzani dokotala wanu ngati mwakhalapo ndi matenda amwazi kapena matenda a Gilbert (kuchepa kwa mphamvu yowononga bilirubin, chinthu chachilengedwe mthupi) komanso ngati mukuchiritsidwa ndi radiation kumimba kapena m'chiuno (dera pakati pa mafupa amchiuno ) kapena ngati mwalandirapo mankhwala amtunduwu. Ngati mukumane ndi izi, pitani kuchipatala nthawi yomweyo: malungo, kuzizira, chifuwa, kapena zizindikilo zina za matenda; kupuma movutikira; kugunda kwamtima; mutu; chizungulire; khungu lotumbululuka; chisokonezo; kutopa kwambiri, kapena kutuluka magazi kapena kuvulala kwachilendo.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti aone momwe thupi lanu likuyankhira irinotecan.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito irinotecan.

Irinotecan imagwiritsidwa ntchito yokha kapena kuphatikiza mankhwala ena kuti athetse khansa ya m'matumbo kapena yam'mbali (khansa yomwe imayamba m'matumbo akulu). Irinotecan ali mgulu la mankhwala opatsirana m'mimba otchedwa topoisomerase I inhibitors. Zimagwira ntchito poletsa kukula kwa maselo a khansa.

Irinotecan amabwera ngati madzi kuti apatsidwe mphindi 90 mkati mwa mtsempha (ndi mtsempha) ndi dokotala kapena namwino. Nthawi zambiri samaperekedwa kamodzi pamlungu, malinga ndi ndandanda yomwe imasinthira sabata limodzi kapena kupitilira apo mukalandira irinotecan ndi sabata limodzi kapena angapo musamalandire mankhwala. Dokotala wanu amasankha nthawi yomwe ingakuthandizeni kwambiri.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu ndikusintha mulingo wanu mukakumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira mankhwala a irinotecan.

Dokotala wanu akhoza kukupatsani mankhwala oletsa kunyansidwa, kusanza musanalandire mlingo uliwonse wa irinotecan. Dokotala wanu amathanso kukupatsani mankhwala ena kuti muchepetse kapena kuthandizira zovuta zina.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Irinotecan nthawi zina imagwiritsidwanso ntchito limodzi ndi mankhwala ena kuti athetse khansa yaying'ono yamapapo yamapapo. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire irinotecan,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi irinotecan, sorbitol, kapena mankhwala aliwonse.
• Uzani dokotala wanu ngati mukumwa ketoconazole (Nizoral). Dokotala wanu angakuuzeni kuti musamwe ketoconazole kwa sabata imodzi musanayambe mankhwala anu ndi irinotecan kapena mukamalandira chithandizo.
• uzani dokotala wanu ngati mukumwa wort ya St. Musamamwe wort wa St. John kwa milungu iwiri musanayambe mankhwala anu ndi irinotecan kapena mukamamwa mankhwala.
• auzeni adotolo ndi asayansi yanu mankhwala ena omwe mungalandire kapena osakulemberani, mavitamini, zowonjezera zakudya ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: atazanavir (Reyataz); gemfibrozil (Lopid); mankhwala a khunyu monga carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal), phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); ndi rifampin (Rifadin, Rimactane, ku Rifamate ndi Rifater). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda ashuga; tsankho la fructose (kulephera kugaya shuga wachilengedwe wopezeka mu zipatso); kapena chiwindi, mapapo, kapena matenda a impso.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena konzekerani kukhala ndi mwana. Inu kapena mnzanu simuyenera kutenga pakati pomwe mukulandira irinotecan. Muyenera kukhala ndi mayeso olimbana ndi mimba musanalandire mankhwalawa. Ngati ndinu wamkazi, gwiritsani ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi 6 mutatha kumwa mankhwala. Ngati ndinu wamwamuna ndipo mnzanu atha kukhala ndi pakati, muyenera kugwiritsa ntchito makondomu mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Ngati inu kapena mnzanu muli ndi pakati mukalandira irinotecan, itanani dokotala wanu. Irinotecan ikhoza kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukalandira jekeseni wa irinotecan, komanso masiku asanu ndi awiri mutatha kumwa mankhwala omaliza.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kolandila jakisoni wa irinotecan.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukulandira irinotecan.
• muyenera kudziwa kuti irinotecan imatha kukupangitsani kukhala ozunguzika kapena kusokoneza masomphenya anu, makamaka patadutsa maola 24 mutalandira mankhwala. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• lankhulani ndi dokotala musanalandire katemera aliyense mukamamwa mankhwala a irinotecan.

Dokotala wanu angakuuzeni zakudya zapadera zomwe mungatsatire kuti muthane ndi kutsegula m'mimba mukamalandira chithandizo. Tsatirani malangizowa mosamala.

Lankhulani ndi dokotala wanu zakudya mphesa ndi kumwa madzi amphesa pamene mukulandira mankhwalawa.

Irinotecan imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kudzimbidwa
• kutupa ndi zilonda mkamwa
• kutentha pa chifuwa
• kusowa chilakolako
• kuonda
• kutayika tsitsi
• kufooka
• kugona
• ululu, makamaka kupweteka kwa msana

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

• kupweteka pachifuwa
• chikasu cha khungu kapena maso
• kutupa m'mimba
• kulemera kosayembekezereka kapena kosazolowereka
• kutupa kwa mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
• zidzolo
• ming'oma
• kuyabwa
• kuvuta kupuma kapena kumeza

Anthu ena omwe adalandira irinotecan adayamba kuundana m'miyendo, m'mapapu, muubongo, kapena m'mitima. Palibe chidziwitso chokwanira chodziwitsa ngati irinotecan idapangitsa magazi kuundana. Lankhulani ndi dokotala wanu za kuopsa kolandira irinotecan.

Irinotecan imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• zilonda zapakhosi, malungo, kuzizira, chifuwa ndi zizindikiro zina za matenda
• kutsegula m'mimba kwambiri

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Camptosar^®

• CPT-11