Mlembi: Clyde Lopez
Tsiku La Chilengedwe: 22 Kulayi 2021
Sinthani Tsiku: 19 Novembala 2024
Anonim
Efficacy and safety of adjunctive lacosamide in the treatment of PGTCS
Kanema: Efficacy and safety of adjunctive lacosamide in the treatment of PGTCS

Zamkati

Lacosamide imagwiritsidwa ntchito poletsa kugwa pang'ono (khunyu komwe kumangokhudza gawo limodzi lokha laubongo) mwa akulu ndi ana azaka 4 kapena kupitirira. Lacosamide imagwiritsidwanso ntchito limodzi ndi mankhwala ena kuti athetse kugwidwa kwapadera kwa tonic-clonic (komwe kumadziwika kuti kulanda kwakukulu; kulanda komwe kumakhudza thupi lonse) mwa akulu ndi ana azaka 4 zakubadwa kapena kupitilira apo. Lacosamide ali mgulu la mankhwala otchedwa anticonvulsants. Zimagwira ntchito pochepetsa magwiridwe antchito amagetsi muubongo.

Lacosamide imabwera ngati piritsi komanso ngati yankho (madzi) kuti mutenge pakamwa. Nthawi zambiri amatengedwa kawiri patsiku kapena wopanda chakudya. Tengani lacosamide mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani lacosamide ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osatafuna, gawanika kapena kuwaphwanya.


Ngati mukumwa yankho la m'kamwa, gwiritsani ntchito muyeso wa supuni kapena syringe yapakamwa kuti muyese kuchuluka kwa madzi omwe amafunikira pa mulingo uliwonse. Osagwiritsa ntchito supuni yanyumba yokhazikika. Ngati muli ndi nasogastric (NG) kapena chubu cha m'mimba, dokotala wanu kapena wamankhwala akufotokozerani momwe mungakonzekerere lacosamide kuti ayipereke.

Dokotala wanu angayambe ndi mlingo wochepa wa lacosamide ndipo pang'onopang'ono muwonjezere mlingo wanu, osati kangapo kamodzi pa sabata.

Lacosamide itha kuthandizira kuwongolera matenda anu koma sangachiritse. Zitha kutenga milungu ingapo kapena kupitilira apo kuti mumve bwino lacosamide. Pitirizani kumwa lacosamide ngakhale mukumva bwino. Osasiya kumwa lacosamide osalankhula ndi dokotala, ngakhale mutakhala ndi zovuta zina monga kusintha kosasintha kwamakhalidwe kapena malingaliro. Ngati mwasiya mwadzidzidzi kumwa lacosamide, kugwidwa kwanu kumatha kuchitika pafupipafupi. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.


Musanatenge lacosamide,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la lacosamide, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a lacosamide kapena yankho lamlomo. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: beta blockers monga atenolol (Tenormin, mu Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), ndi propranolol (Hemangeol, Inderal); calcium blockers monga amlodipine (Norvasc, ku Caduet, ku Lotrel, ku Exforge, ena), diltiazem (Cardizem, Cartia, Tiazac, ena), felodipine, isradipine, nicardipine, nifedipine (Procardia), nimodipine (Nymalize), nisoldipine ( Sular), ndi verapamil (Calan, Verelan, ku Tarka); ndi mankhwala a kugunda kwamtima mosasinthasintha monga amiodarone (Nexterone, Pacerone), digoxin (Lanoxin), dronedarone (Multaq), flecainide (Tambocor), propafenone (Rythmol), quinidine (ku Nuedexta), ndi sotalol (Betapace, Sorine, Sotylize). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi lacosamide, chifukwa chake onetsetsani kuti mumauza dokotala za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • uzani dokotala wanu ngati pakadali pano kapena mudamwa mowa wambiri, kugwiritsa ntchito mankhwala osokoneza bongo, kapena mankhwala osokoneza bongo omwe mumamwa. Komanso muuzeni dokotala ngati mwakhalapo ndi vuto lakukhumudwa, mavuto amisala, malingaliro ofuna kudzipha kapena machitidwe; kugunda kwamtima mosasinthasintha, matenda a mtima, kupumira pacemaker, kulephera kwa mtima, kapena mavuto ena amtima; matenda ashuga (kuwonongeka kwa mitsempha yoyambitsidwa ndi matenda ashuga); kapena chiwindi kapena matenda a impso.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga lacosamide, itanani dokotala wanu.
  • Muyenera kudziwa kuti lacosamide imatha kukupangitsani kukhala ozunguzika kapena kuwodzera ndipo itha kuyambitsa kusawona bwino kapena mavuto chifukwa chogwirizana. Osayendetsa galimoto, kugwiritsa ntchito makina, kapena kuchita nawo zinthu zomwe zimafunikira kukhala tcheru kapena kulumikizana mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
  • muyenera kudziwa kuti thanzi lanu lingasinthe m'njira zosayembekezereka ndipo mutha kudzipha (kuganiza zodzipweteka kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero) mukamamwa lacosamide. Chiwerengero chochepa cha achikulire ndi ana azaka 5 zakubadwa kapena kupitilira (pafupifupi 1 mwa anthu 500) omwe adatenga ma anticonvulsants ngati lacosamide kuti athetse zovuta zosiyanasiyana panthawi yamaphunziro azachipatala adadzipha panthawi yomwe amalandira chithandizo. Ena mwa anthuwa adayamba kudzipha pakangotha ​​sabata limodzi atayamba kumwa mankhwalawo. Pali chiopsezo kuti mutha kusintha thanzi lanu lam'mutu mukamamwa mankhwala a anticonvulsant monga lacosamide, koma pakhoza kukhalanso pachiwopsezo kuti musinthe m'maganizo anu ngati matenda anu sakuchiritsidwa. Inu ndi dokotala wanu muwona ngati kuopsa kokumwa mankhwala a anticonvulsant ndiokulirapo kuposa kuopsa kosamwa mankhwalawo. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: mantha; kusakhazikika kapena kusakhazikika; kukwiya kwatsopano kapena kukulira, nkhawa, kapena kukhumudwa; kuchita zofuna zawo; zovuta kugona kapena kugona; aukali, aukali, kapena achiwawa; mania (kukwiya, kusangalala modabwitsa); kuyankhula kapena kuganiza zofuna kudzipweteka kapena kudzipha; kapena kusintha kwina kulikonse pamakhalidwe kapena malingaliro. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.
  • Muyenera kudziwa kuti lacosamide imatha kuyambitsa chizungulire, kupepuka mutu, kukomoka, kapena kugunda kwamtima, makamaka mukadzuka msanga pamalo abodza. Mukayamba kukhala ndi zizindikilozi, gonani ndi miyendo yanu mutakweza mpaka mumve bwino, ndipo itanani dokotala nthawi yomweyo.
  • ngati muli ndi phenylketonuria (PKU, mkhalidwe wobadwa nawo momwe muyenera kudya chakudya chapadera kuti muchepetse kuchepa kwamaganizidwe), muyenera kudziwa kuti lacosamide solution solution ili ndi aspartame yomwe imapanga phenylalanine.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Lacosamide angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • nseru
  • kusanza
  • kutsegula m'mimba
  • kusawona bwino kapena masomphenya awiri
  • mayendedwe osalamulirika amaso
  • chizungulire
  • mutu
  • Kusinza
  • kugwedezeka kosalamulirika kwa gawo lina la thupi
  • mavuto ndi mgwirizano, kulimbitsa thupi, kapena kuyenda
  • kufooka
  • kuyabwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

  • kuthamanga kapena kugunda kwamtima kapena kugunda
  • kupuma movutikira
  • kugunda kochedwa mtima
  • kupweteka pachifuwa
  • kukomoka
  • kutupa kwa nkhope, mmero, lilime, milomo, ndi maso
  • malungo
  • zidzolo
  • kutopa
  • chikasu cha khungu kapena maso
  • mkodzo wakuda

Lacosamide angayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Musamaimitse yankho lakumlomo. Chotsani njira iliyonse yosagwiritsidwa ntchito pakamwa patatha milungu 7 mutatsegula botolo.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Lacosamide ndi mankhwala olamulidwa. Malangizo amatha kudzazidwanso kangapo; funsani wamankhwala wanu ngati muli ndi mafunso.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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