Pegloticase jekeseni

Zamkati

• Asanalandire jakisoni wa pegloticase,
• Pegloticase jekeseni imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

Jekeseni wa Pegloticase imatha kuyambitsa mavuto akulu kapena owopsa. Izi zimachitika kwambiri pakadutsa maola awiri mutalandira kulowetsedwa koma zimatha kuchitika nthawi iliyonse mukalandira chithandizo. Kulowetsedwa kuyenera kuperekedwa ndi dokotala kapena namwino pamalo azisamaliro pomwe izi zitha kuchiritsidwa. Muthanso kulandira mankhwala ena musanalowetsedwe ndi pegloticase kuti muthe kupewa kuyankha. Dokotala wanu kapena namwino adzakuyang'anirani mosamala mukalandira jakisoni wa pegloticase komanso kwakanthawi pambuyo pake. Uzani dokotala wanu ngati mukukumana ndi izi mwa izi kapena mukamakulowetsani: zovuta kumeza kapena kupuma; kupuma; ukali; kutupa kwa nkhope, mmero, lilime kapena milomo; ming'oma; kufiira mwadzidzidzi kwa nkhope, khosi kapena chifuwa chapamwamba; zidzolo; kuyabwa; khungu lofiira; kukomoka; chizungulire; kupweteka pachifuwa; kapena zolimba pachifuwa. Ngati mukumva kanthu, dokotala wanu akhoza kuchepetsa kapena kusiya kulowetsedwa.

Pegloticase jekeseni imatha kubweretsa mavuto akulu amwazi. Uzani dokotala wanu ngati muli ndi vuto la glucose-6-phosphate dehydrogenase (G6PD) (matenda obadwa nawo amwazi). Dokotala wanu angakuyeseni ngati muli ndi vuto la G6PD musanayambe kulandira jakisoni wa pegloticase. Ngati muli ndi vuto la G6PD, dokotala wanu angakuuzeni kuti simungalandire jakisoni wa pegloticase. Komanso muuzeni dokotala ngati muli ochokera ku Africa, Mediterranean (kuphatikiza Kumwera kwa Europe ndi Middle East), kapena ochokera ku Southern Asia.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti muwone momwe thupi lanu limayankhira jakisoni wa pegloticase ndipo akhoza kuyimitsa chithandizo chanu ngati mankhwalawa sakugwira ntchito.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wa pegloticase ndipo nthawi iliyonse yomwe mumalandira mankhwalawo. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Jekeseni wa pegloticase amagwiritsidwa ntchito pochizira gout (mwadzidzidzi, kupweteka kwambiri, kufiira, ndi kutupa pachilumikizo chimodzi kapena zingapo zomwe zimayambitsidwa ndi chinthu chambiri chotchedwa uric acid m'magazi) mwa achikulire omwe sangamwe kapena sanayankhe mankhwala ena . Pegloticase jakisoni ali mgulu la mankhwala otchedwa PEGylated uric acid ma enzyme. Zimagwira ntchito pochepetsa uric acid m'thupi. Jekeseni wa Pegloticase amagwiritsidwa ntchito popewa kuukira kwa gout koma osawachiza akachitika.

Jekeseni wa Pegloticase imabwera ngati yankho (madzi) kuti alowe jakisoni (mumtsempha) ndi dokotala kapena namwino kuofesi yazachipatala kapena kuchipatala. Nthawi zambiri amaperekedwa kamodzi pamasabata awiri. Zingatenge osachepera maola 2 kuti mulandire jakisoni wa pegloticase.

Zitha kutenga miyezi ingapo jekeseni wa pegloticase isanayambe kupewa matenda a gout. Jekeseni wa Pegloticase itha kukulitsa kuchuluka kwa ziwopsezo za gout m'miyezi itatu yoyamba yamankhwala anu. Dokotala wanu akhoza kukupatsirani mankhwala ena monga colchicine kapena anti-steroidal anti-inflammatory drug (NSAID) kuti muteteze kuukira kwa gout m'miyezi isanu ndi umodzi yoyamba yamankhwala anu. Pitirizani kulandira jakisoni wa pegloticase ngakhale mutakumana ndi gout mukamalandira chithandizo.

Pegloticase jakisoni amalamulira gout koma samachiritsa. Pitirizani kulandira jakisoni wa pegloticase ngakhale mukumva bwino. Osasiya kulandira jakisoni wa pegloticase osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa pegloticase,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la pegloticase, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jakisoni wa pegloticase. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: allopurinol (Aloprim, Lopurin, Zyloprim) ndi febuxostat (Uloric). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati mwakhala mukulephera mtima, kuthamanga kwa magazi, kapena matenda amtima.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa pegloticase, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Pegloticase jekeseni imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kudzimbidwa
• kuvulaza
• chikhure

Pegloticase jekeseni ingayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Funsani wamankhwala wanu mafunso aliwonse omwe ali nawo okhudza pegloticase jekeseni.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Alireza^®