Boceprevir

Zamkati

• Musanatenge boceprevir,
• Boceprevir itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Boceprevir imagwiritsidwa ntchito limodzi ndi mankhwala ena awiri (ribavirin [Copegus, Rebetol] ndi peginterferon alfa [Pegasys]) kuchiza matenda otupa chiwindi a C (matenda opatsirana omwe amawononga chiwindi) mwa anthu omwe sanalandire chithandizo cha matendawa kapena omwe Matendawa sanasinthe pomwe amathandizidwa ndi ribavirin ndi peginterferon alfa okha. Boceprevir ali mgulu la mankhwala otchedwa protease inhibitors. Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka hepatitis C (HCV) mthupi. Boceprevir sangalepheretse kufalikira kwa matenda a chiwindi a C kwa anthu ena.

Boceprevir imabwera ngati kapisozi woti atenge pakamwa. Nthawi zambiri amatengedwa ndi chakudya kapena chotupitsa katatu patsiku (maola 7 kapena 9 aliwonse). Tengani boceprevir mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani boceprevir ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Mutenga peginterferon alfa ndi ribavirin kwa milungu inayi musanayambe kumwa mankhwala ndi boceprevir. Kenako mutenga mankhwala onse atatu kwa milungu 12 mpaka 44. Pambuyo panthawiyi, musiya kumwa boceprevir, koma mutha kupitiriza kumwa peginterferon alfa ndi ribavirin kwa milungu ingapo. Kutalika kwa chithandizo chanu kumadalira momwe mulili, momwe mumayankhira mankhwalawo, komanso ngati mukukumana ndi zovuta zina. Pitirizani kumwa boceprevir, peginterferon alfa, ndi ribavirin malinga ngati akupatsani dokotala. Osasiya kumwa mankhwalawa osalankhula ndi dokotala ngakhale mukumva bwino.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba kulandira mankhwala ndi boceprevir ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge boceprevir,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi matupi awo sagwirizana ndi boceprevir, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a boceprevir. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala ngati mukumwa mankhwala aliwonse otsatirawa kapena mankhwala azitsamba: alfuzosin (Uroxatral); mankhwala a ergot monga dihydroergotamine (DHE 45, Migranal), ergonovine, ergotamine (Ergomar, ku Cafergot, ku Migergot) kapena methylergonovine; cisapride (Propulsid) (sikupezeka ku U.S.); drospirenone (m'miyamwa ina monga Beyaz, Gianvi, Ocella, Safyral, Yasmin, Yaz, ndi Zarah); lovastatin (Altoprev, Mevacor); mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, kapena phenytoin (Dilantin); midazolam yotengedwa pakamwa; pimozide (Orap); rifampin (Rifadin, Rimactane, ku IsonaRif, ku Rifamate, ku Rifater); sildenafil (mtundu wa Revatio wokha womwe umagwiritsidwa ntchito matenda am'mapapo); simvastatin (Simcor, ku Vytorin); tadalafil (mtundu wa Adcirca wokha womwe umagwiritsidwa ntchito matenda am'mapapo); Chingwe cha St. kapena triazolam (Halcion). Dokotala wanu angakuuzeni kuti musatenge boceprevir ngati mukumwa mankhwala amodzi kapena angapo.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: alprazolam (Niravam, Xanax); anticoagulants ('magazi ochepetsa magazi') monga warfarin (Coumadin); mankhwala oletsa mafungal monga itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), ndi voriconazole (Vfend); atorvastatin (Lipitor, mu Caduet); chifuwa (Tracleer); budesonide (Pulmicort, Rhinocort, Symbicort); buprenorphine (Buprenex, Butrans, Subutex, Suboxone); zotsekemera za calcium monga felodipine (Plendil), nicardipine (Cardene), ndi nifedipine (Adalat, Afeditab, Procardia); clarithromycin (Biaxin); colchicine (Colcrys, mu Col-Probenecid); cyclosporine (Gengraf, Neoral, Sandimmune); desipramine (Norpramin); dexamethasone; mankhwala ena osagwira erectile monga sildenafil (Viagra), tadalafil (Cialis), ndi vardenafil (Levitra, Staxyn); mankhwala ena a HIV monga atazanavir otengedwa ndi ritonavir, darunavir otengedwa ndi ritonavir, efavirenz (Sustiva, ku Atripla), lopinavir yotengedwa ndi ritonavir, ndi ritonavir (Norvir, ku Kaletra); mankhwala ena osagunda pamtima monga amiodarone (Cordarone, Pacerone), digoxin (Lanoxin), flecainide (Tambocor), propafenone (Rythmol), ndi quinidine; methadone (Dolophine, Methadose); midazolam amapatsidwa kudzera m'mitsempha (mumtsempha); rifabutin (Mycobutin); salmeterol (Serevent, ku Advair); mankhwala (Rapamune); tacrolimus (Prograf); ndi trazodone. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati mudadalitsidwapo ziwalo, ndipo ngati mudakhalapo kapena mudakhalapo ndi kuchepa kwa magazi (osakwanira magazi ofiira okwanira mumwazi kuti anyamule mpweya mthupi lonse), kachilombo koyambitsa matenda a chitetezo cha mthupi (HIV), adapeza chitetezo m'thupi syndrome (Edzi), matenda ena aliwonse omwe amakhudza chitetezo chamthupi anu, kapena hepatitis B (matenda omwe amawononga chiwindi) kapena mtundu uliwonse wa matenda a chiwindi kupatula hepatitis C.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa boceprevir.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mutha kutenga pakati. Ngati ndinu wamwamuna, auzeni dokotala ngati mnzanu ali ndi pakati, akukonzekera kutenga pakati, kapena atha kutenga pakati. Boceprevir iyenera kutengedwa ndi ribavirin yomwe imatha kuvulaza mwanayo. Muyenera kugwiritsa ntchito njira ziwiri zakulera kuti muchepetse mimba mwa inu kapena mnzanu mukamalandira mankhwalawa komanso kwa miyezi 6 mutalandira chithandizo. Lankhulani ndi dokotala wanu za njira zomwe muyenera kugwiritsa ntchito; Njira zolerera za mahomoni (mapiritsi oletsa kubereka, zigamba, ma implants, mphete, kapena jakisoni) sizingagwire bwino ntchito kwa amayi omwe akumwa mankhwalawa. Inu kapena mnzanu muyenera kuyesedwa ngati muli ndi pakati mwezi uliwonse mukamalandira chithandizo komanso kwa miyezi 6 mutalandira chithandizo. Ngati inu kapena mnzanu mumakhala ndi pakati mukamamwa mankhwalawa, itanani dokotala wanu mwachangu.
• uzani dokotala wanu ngati mukuyamwitsa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo wosowa ndi chakudya mukangokumbukira. Komabe, ngati kutangotsala maola 2 kapena ochepa isanakwane nthawi yanu yotsatira, tulukani mlingo womwe mwaphonyawo ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Boceprevir itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• sinthani kuti mulawe
• kusowa chilakolako
• kutopa kwambiri
• kuvuta kugona kapena kugona
• kupsa mtima
• kutayika tsitsi
• khungu lowuma
• zidzolo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kupuma movutikira
• chizungulire
• kukomoka
• kufooka
• zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda

Boceprevir ingayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Mutha kusunga makapisozi kutentha kwapakati komanso kutentha kwambiri ndi chinyezi (osati kubafa) kwa miyezi itatu. Muthanso kusungira makapisozi mufiriji mpaka tsiku lomaliza lolemba palemba litadutsa. Tayani mankhwala aliwonse omwe ndi achikale kapena osafunikanso. Lankhulani ndi wamankhwala wanu za momwe mungagwiritsire ntchito mankhwala anu.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone kuyankha kwa thupi lanu ku boceprevir.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Wopambana^®