Zamgululi

Zamkati

• Musanatenge sonidegib,
• Sonidegib itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kumwa sonidegib ndikuimbira dokotala nthawi yomweyo:

Kwa odwala onse:

Sonidegib sayenera kutengedwa ndi amayi omwe ali ndi pakati kapena omwe angakhale ndi pakati. Pali chiopsezo chachikulu kuti sonidegib isokoneze mimba kapena ipangitse mwanayo kubadwa ndi zolemala zobadwa (zovuta zomwe zimakhalapo pobadwa).

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi sonidegib ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena pitani patsamba la wopanga kuti mupeze Medication Guide.

Osapereka magazi kapena zopangira magazi mukamamwa sonidegib komanso kwa miyezi 20 mutalandira chithandizo.

Lankhulani ndi dokotala wanu za kuopsa kotenga sonidegib.

Kwa odwala achikazi:

Ngati mutha kutenga pakati, muyenera kupewa kutenga mimba mukamalandira sonidegib. Muyenera kukhala ndi mayeso olakwika okhudzana ndi mimba musanamwe mankhwala. Muyenera kugwiritsa ntchito njira zovomerezeka zolerera mukamalandira chithandizo komanso kwa miyezi yosachepera 20 chithandizo chanu chitamalizidwa. Dokotala wanu angakuuzeni mitundu ya njira zolerera zovomerezeka.

Ngati mukuganiza kuti muli ndi pakati, simusowa msambo, kapena kugonana musanagwiritse ntchito njira zakulera mukamamwa sonidegib kapena patatha miyezi 20 mutalandira chithandizo, pitani kuchipatala msanga.

Kwa odwala amuna:

Muyenera kugwiritsa ntchito kondomu, ngakhale mutakhala ndi vasectomy (opareshoni yoletsa umuna kuti usatuluke mthupi lanu ndikupangitsani kutenga pakati), nthawi iliyonse mukamagonana ndi mayi yemwe ali ndi pakati kapena wokhoza kutenga pakati mukatenga sonidegib, komanso kwa miyezi yosachepera 8 mutalandira chithandizo. Uzani dokotala wanu nthawi yomweyo ngati mwagonana mosadziteteza ndi mayi yemwe angatenge pakati kapena ngati mukuganiza pazifukwa zilizonse kuti mnzanu ali ndi pakati. Osapereka umuna mukamamwa sonidegib kapena pakatha miyezi 8 mutalandira chithandizo.

Sonidegib imagwiritsidwa ntchito pochizira basal cell carcinoma (BCC; mtundu wa khansa yapakhungu) mwa akulu omwe ali ndi khansa yomwe yabwerera pambuyo pa opaleshoni kapena radiation, kapena kwa achikulire omwe sangachiritsidwe ndi opaleshoni kapena radiation. Sonidegib ali mgulu la mankhwala otchedwa hedgehog pathway inhibitors. Zimagwira ntchito poletsa ntchito ya puloteni yomwe imafotokoza kuti maselo a khansa achulukane. Izi zimathandiza kuletsa kapena kuchepetsa kufalikira kwa maselo a khansa ndipo zitha kuthandiza kuchepa kwa zotupa.

Sonidegib amabwera ngati kapisozi woti amutenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku wopanda kanthu, osachepera ola limodzi musanadye kapena maola awiri mutadya. Tengani sonidegib nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani sonidegib ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu angafunike kusokoneza kapena kuyimitsa chithandizo chanu kutengera kuyankha kwanu ku sonidegib ndi zovuta zilizonse zomwe mungakumane nazo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge sonidegib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la sonidegib, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a sonidegib. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: atazanavir (Reyataz); maantifungal ena monga fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, posaconazole (Noxafil), ndi voriconazole (Vfend); diltiazem (Cardizem, Cartia, Tiazac, ena); efavirenz (Sustiva, ku Atripla); modafinil (Provigil); nefazodone; rifabutin (Mycobutin); rifampin (Rifadin, Rifamate, Rifater, Rimactane); saquinavir (Invirase); mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, ndi phenytoin (Dilantin, Phenytek); ndi telithromycin (Ketek). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi sonidegib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St. Dokotala wanu mwina angakuuzeni kuti musatenge wort ya St. John mukamamwa sonidegib.
• uzani dokotala wanu ngati mwakhalapo kapena munakhalapo ndi matenda aminyewa.
• Uzani dokotala wanu ngati mukuyamwitsa. Dokotala wanu akhoza kukuwuzani kuti musamamwe mkaka mukamamwa sonidegib komanso kwa miyezi 20 mutalandira chithandizo.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Sonidegib itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kupweteka m'mimba
• kusowa chilakolako
• kuonda
• nseru
• kusanza
• kusintha kwa kulawa chakudya
• kutayika tsitsi
• kuyabwa
• kufooka
• kutopa kwambiri
• kupweteka
• anasiya kusamba

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kumwa sonidegib ndikuimbira dokotala nthawi yomweyo:

• kutuluka kwa minofu
• kupweteka kwa minofu, kufatsa kapena kufooka
• mkodzo wamdima kapena wa kola
• kuchepa pokodza
• kulephera kukodza

Sonidegib ikhoza kuchepetsa kubala mwa amayi. Lankhulani ndi dokotala wanu za kuopsa kotenga sonidegib ngati muli ndi nkhawa zokhudzana ndi chonde.

Sonidegib itha kuyambitsa kukula kuyima koyambirira kwa ana. Izi mankhwala ali osavomerezeka ntchito ana.

Sonidegib itha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Odomzo^®