Mlembi: Gregory Harris
Tsiku La Chilengedwe: 13 Epulo 2021
Sinthani Tsiku: 19 Novembala 2024
Anonim
Paritaprevir/ritonavir/ombitasvir/dasabuvir for HCV GT1 - Video abstract 80226
Kanema: Paritaprevir/ritonavir/ombitasvir/dasabuvir for HCV GT1 - Video abstract 80226

Zamkati

Dasabuvir, ombitasvir, paritaprevir, ndi ritonavir sichikupezeka ku United States.

Mutha kukhala ndi kachilombo ka hepatitis B (kachilombo kamene kamagwira chiwindi ndipo kakhoza kuwononga chiwindi kwambiri) koma osakhala ndi zisonyezo za matendawa. Poterepa, kutenga dasabuvir, ombitasvir, paritaprevir, ndi ritonavir kumatha kuwonjezera chiopsezo kuti matenda anu akhoza kukhala owopsa kapena owopseza moyo ndipo mudzakhala ndi zizindikiro. Uzani dokotala wanu ngati mwakhalapo ndi kachilombo ka hepatitis B. Dokotala wanu amalamula kuti mukayezetse magazi kuti muwone ngati mwadwala matenda a hepatitis B. Dokotala wanu adzakuyang'anirani ngati muli ndi matenda a chiwindi cha B mkati ndi miyezi ingapo mutalandira chithandizo. Ngati ndi kotheka, dokotala wanu akhoza kukupatsani mankhwala ochizira matendawa musanachitike komanso mukamamwa mankhwalawa kuphatikiza dasabuvir, ombitasvir, paritaprevir, ndi ritonavir. Ngati mukumane ndi zizindikiro izi mukamalandira chithandizo kapena mutalandira chithandizo, itanani dokotala wanu mwachangu: kutopa kwambiri, khungu lachikaso kapena maso, kusowa chilakolako, kunyoza kapena kusanza, mipando yotuwa, kupweteka m'mimba, kapena mkodzo wakuda.


Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena musanadye, nthawi, komanso mutalandira chithandizo kuti muwone momwe thupi lanu lingayankhire pophatikiza dasabuvir, ombitasvir, paritaprevir, ndi ritonavir.

Lankhulani ndi dokotala wanu za chiopsezo chotenga dasabuvir, ombitasvir, paritaprevir, ndi ritonavir.

Dasabuvir, ombitasvir, paritaprevir, ndi ritonavir amagwiritsidwa ntchito paokha kapena kuphatikiza ndi ribavirin (Copegus, Rebetol, Ribasphere) kuchiza matenda a chiwindi (C) a nthawi yayitali (kutupa kwa chiwindi choyambitsidwa ndi kachilombo). Dasabuvir ndi non-nucleoside NS5B polymerase inhibitor. Zimagwira ntchito pochepetsa kuchuluka kwa HCV mthupi. Ombitasvir ndi kachilombo ka hepatitis C (HCV) NS5A inhibitor. Zimagwira ntchito poletsa kachilombo kamene kamayambitsa matenda a chiwindi a C kufalikira m'thupi. Paritaprevir ndi protease inhibitor. Zimagwira ntchito pochepetsa kuchuluka kwa HCV mthupi. Ritonavir ndi protease inhibitor. Zimathandizira kuwonjezera kuchuluka kwa paritaprevir mthupi kuti mankhwala azikhala ndi gawo lalikulu.


Kuphatikiza kwa dasabuvir, ombitasvir, paritaprevir, ndi ritonavir kumabwera ngati mapiritsi otalikitsa (otenga nthawi yayitali) oti atenge pakamwa. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani dasabuvir, ombitasvir, paritaprevir, ndi ritonavir mozungulira nthawi yomweyo tsiku lililonse. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Mapiritsi omasuliridwa amakhala mu phukusi lokhala ndi masiku 28 azamankhwala. Phukusi lililonse la tsiku lililonse limakhala ndi mapiritsi atatu omwe ali ndi dasabuvir, ombitasvir, paritaprevir, ndi ritonavir. Tengani dasabuvir, ombitasvir, paritaprevir, ndi ritonavir (mapiritsi 3) m'mawa uliwonse ndi chakudya. Tsatirani malangizo phukusi lililonse la tsiku lililonse la momwe mungachotsere mapiritsi.

Kumeza mapiritsi otulutsidwa otalikiratu; osagawana, kutafuna, kapena kuwaphwanya.

Pitirizani kumwa dasabuvir, ombitasvir, paritaprevir, ndi ritonavir ngakhale mukumva bwino. Kutalika kwa chithandizo chanu (masabata 12 mpaka 24) kumadalira momwe mulili, momwe mumayankhira mankhwalawo, komanso ngati mukukumana ndi zovuta zina. Osasiya kumwa dasabuvir, ombitasvir, paritaprevir, ndi ritonavir osalankhula ndi dokotala wanu.


Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge dasabuvir, ombitasvir, paritaprevir, ndi ritonavir,

  • uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi dasabuvir, ombitasvir, paritaprevir, ndi ritonavir, mankhwala ena aliwonse, kapena chilichonse chopezeka mu dasabuvir, ombitasvir, paritaprevir, ndi mapiritsi otulutsa ritonavir. Ngati mwakhala mukukumana ndi vuto lalikulu kapena lakuwopseza moyo pa ritonavir (kuthamanga, kuphulika kapena khungu), dokotala wanu angakuuzeni kuti musatenge dasabuvir, ombitasvir, paritaprevir, ndi ritonavir. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
  • Uzani dokotala ngati mukumwa alfuzosin (Uroxatral); apalutamide (Erleada); atorvastatin (Lipitor, mu Caduet); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol); cisapride (Propulsid; sichikupezeka ku U.S.); dronearone (Multaq); efavirenz (Sustiva, ku Atripla); mankhwala okhala ndi ergot monga dihydroergotamine mesylate (DHE 45, Migranal), ergotamine (Ergomar, ku Cafergot, ku Migergot), ndi methylergonovine (Methergine); ethinyl estradiol njira zolerera zamkamwa monga zina ('mapiritsi oletsa kubereka'), zigamba, mphete za nyini, ndi zinthu zina za ethinyl estradiol; everolimus (Wothandizira, Zortress); gemfibrozil (Lopid); lomitapide (Wowonjezera); lovastatin (Altoprev); lurasidone (Latuda); midazolam (pakamwa); phenytoin (Dilantin, Phenytek); phenobarbital; pimozide (Orap); ranolazine (Ranexa); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); sildenafil (Revatio) yothandizira matenda oopsa am'mapapo mwanga; simvastatin (Flolipid, Zocor, ku Vytorin); mankhwala (Rapamune); Chingwe cha St. tacrolimus (Astagraf XL, Envarsus XR, Prograf); kapena triazolam (Halcion). Komanso, uzani dokotala ngati mukumwa colchicine (Colcrys, Mitigare) ndipo muli ndi chiwindi kapena matenda a impso. Dokotala wanu angakuuzeni kuti musamwe dasabuvir, ombitasvir, paritaprevir, ndi ritonavir ngati mukumwa mankhwala amodzi kapena angapo.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: acetaminophen ndi hydrocodone (Anexsia, Zyfrel); alprazolam (Xanax); angiotensin receptor blockers (ARBs) monga candesartan (Atacand, ku Atacand HCT), losartan (Cozaar, ku Hyzaar), kapena valsartan (Diovan, ku Diovan HCT, ku Exforge); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); buprenorphine ndi naloxone (Suboxone, Zubsolv); calcium blockers monga amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, ena), nifedipine (Adalat, Procardia), kapena verapamil (Calan, Verelan, ena); carisoprodol (Soma); cyclobenzaprine (Amrix); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); elagolix (Orilissa); encorafenib (Braftovi); fostamatinib (Tavalisse); fluticasone (Flonase, Flovent, ku Advair); furosemide (Lasix); ibrutinib (Imbruvica); ivosidenib (Tibsovo); ketoconazole; mankhwala a kugunda kwamtima mosasinthasintha monga amiodarone (Nexterone, Pacerone), bepridil (sakupezekanso ku US), disopyramide (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), kapena quinidine (ku Nuedexta); metformin (Glucophage, Riomet, ena); omeprazole (Prilosec); pravastatin (Pravachol); quetiapine (Seroquel); rilpivirine (Edurant; ku Complera, ku Odefsey); ritonavir (Norvir, ku Kaletra) amagwiritsidwa ntchito limodzi ndi HIV protease inhibitors monga atazanavir (Reyataz), darunavir (Prezista), ndi lopinavir (ku Kaletra); rosuvastatin (Crestor); salmeterol (Serevent, ku Advair); ndi voriconazole (Vfend). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • auzeni adotolo ngati muli ndi matenda amtundu wa chiwindi kupatula hepatitis C. Dokotala wanu angakuuzeni kuti musamwe dasabuvir, ombitasvir, paritaprevir, ndi ritonavir.
  • auzeni adotolo ngati mudalandilidwa chiwindi, matenda ashuga, kapena kachilombo ka HIV.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga dasabuvir, ombitasvir, paritaprevir, ndi ritonavir, itanani dokotala wanu.
  • Muyenera kudziwa kuti dasabuvir, ombitasvir, paritaprevir, ndi ritonavir zitha kuchepetsa mphamvu yolerera yapa mahomoni (mapiritsi oletsa kubala, zigamba, mphete, zopangira, jakisoni, ndi zida za intrauterine). Gwiritsani ntchito njira ina yolerera pamene mukumwa dasabuvir, ombitasvir, paritaprevir, ndi ritonavir komanso kwa masabata awiri mutatha kumwa. Lankhulani ndi dokotala wanu za mitundu yoletsa yomwe ingakuthandizireni mukamalandira chithandizo cha dasabuvir, ombitasvir, paritaprevir, ndi ritonavir.
  • kumbukirani kuti musamamwe mowa pasanathe maola 4 mutatenga dasabuvir, ombitasvir, paritaprevir, ndi mapiritsi otulutsa ritonavir.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ndikofunika kuti musaphonye kapena kudumpha mlingo uliwonse. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Dasabuvir, ombitasvir, paritaprevir, ndi ritonavir zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kuvuta kugona kapena kugona
  • chifuwa
  • kupsa mtima
  • mutu
  • kutsegula m'mimba
  • kutuluka kwa minofu

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu

  • zidzolo
  • kufiira kwa khungu
  • kuyabwa
  • ming'oma
  • kutopa kapena kusowa mphamvu
  • kufooka
  • chisokonezo

Dasabuvir, ombitasvir, paritaprevir, ndi ritonavir zitha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwalawa mu katoni yomwe idabwera, yotsekedwa mwamphamvu, komanso kuti ana asafikire. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Musachotse mapiritsi kuchokera paketi ya tsiku ndi tsiku yopangidwa ndi wopanga mpaka atakonzeka kuwamwa.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Viekira XR® (monga chinthu chophatikiza chophatikiza Dasabuvir, Ombitasvir, Paritaprevir, ndi Ritonavir)
Idasinthidwa Komaliza - 08/15/2020

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